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ARVO Annual Meeting Abstract June 2024

OpRegen retinal pigment epithelial (RPE) cell therapy engrafts within the RPE of Gottingen mini-pigs by 4-weeks post-administration via subretinal delivery

Rachel Nicole Andrews; Henry E Wiley; Yuichiro Ogura; Amy Shelton; Tammy Tam; Ryan Boyd; Victoria Stevenson; Tracy Carlson; Colin Jennings; Kyle DePlancke; Vladimir Bantseev

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5416.

Retina October 2022

Direct Tie2 Agonists Stabilize Vasculature for the Treatment of Diabetic Macular Edema

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Nicholas J. Agard; Gu Zhang; John Ridgeway; Danielle M. Dicara; Phillip Y. Chu; Rachana Ohri; Sarah Sanowar; Jean-Michel Vernes; Hannah Chi; Jiameng Zhang; Emily Holz; Maciej Paluch; Guannan He; Yingjia Benson; Jianhuan Zhang; Pamela Chan; Nga Tang; Prachi Javale; Blair Wilson; Kathy Barrett; Rebecca K. Rowntree; Julie Hang; Y. Gloria Meng; Phil Hass; Germaine Fuh; Robert Piskol; Vladimir Bantseev; Kelly M. Loyet; John C. Tran; Cong Wu; Vahan B. Indjeian; Vittal Shivva; Minhong Yan
TAGS: agonists, diabetic macular edema, vasculature, antibodies
Trans. Vis. Sci. Tech.. 2022; 11(10):27. https://doi.org/10.1167/tvst.11.10.27

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Determination of a No Observed Effect Level (NOEL) for Beta Glucans following a Single Intravitreal Administration to Female Dutch Belted Rabbits

Vladimir Bantseev; Sara Parker; Roxanne Andaya; Chris Schuetz; Brian Christian; Paul E Miller; Helen Booler; Melissa Schutten

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):201.

ARVO Annual Meeting Abstract June 2020

Nonclinical toxicology and biocompatibility program supporting clinical development and registration of the Port Delivery System with ranibizumab

Vladimir Bantseev; Joshua Horvath; Giulio Barteselli; Shrirang Ranade; Maia Mauricio; Daniela Bumbaca; Chris Schuetz; Amy Shelton; Helen Booler

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2966.

Physiology and Pharmacology October 2019

Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow

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Evan A. Thackaberry; Yi Zhou; Christina L. Zuch de Zafra; Germaine Fuh; Chingwei V. Lee; Sarah Sanowar; John B. Ridgway; Aija M. Kusi; Cindy Farman; Helen Booler; Daniel Sheinson; Carol A. Rasmussen; Paul E. Miller; Eric Wakshull; Minhong Yan; Vladimir Bantseev
TAGS: antibodies, anti-vascular endothelial growth factor therapy, aqueous humor, eye, glaucoma, intraocular pressure, macaca fascicularis, primates, signal transduction, mice
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4097-4108. https://doi.org/10.1167/iovs.18-26349

ARVO Annual Meeting Abstract July 2019

Functional and Ultrastructural Assessment of Novel OCT Findings in the Cynomolgus Monkey

Helen Booler; Aija M. Kusi; Nardos Tassew; Christopher Frantz; Matthew Holdren; Phillip Lai; T. Michael Nork; Carol Rasmussen; William Meier; Vladimir Bantseev

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):186.

ARVO Annual Meeting Abstract July 2018

In vivo Effects of CCFD9260S Following Intravitreal Administration to Cynomolgus Monkeys

Helen S Booler; Nardos Tassew; Aija MacKenzie; Hong Liu; Deborah O'Connor; Florence Lorget; Paul E Miller; Tim Streit; T Michael Nork; James N Ver Hoeve; Cinzia Stella; Yanqiu Liu; Daniela Bumbaca; Vladimir Bantseev

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):80.

ARVO Annual Meeting Abstract July 2018

The Presence of Protein in Formulation Ameliorates Retinal Changes Observed on OCT Following Intravitreal Administration of Hyperosmotic Solution in Cynomolgus Monkeys

Nardos Tassew; Vladimir Bantseev; Aija McKenzie; Roxanne Andaya; Debbie O'Connor; Daniel Sheinson; Carol A Rasmussen; T Michael Nork; Tim Streit; Helen S Booler; Florence Lorget

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5828.

ARVO Annual Meeting Abstract July 2018

Development of Minipigs Surgical Model: Cauterization of the Choroid Following Scleral Dissection Mitigates Risk of Post-Operative Vitreous Hemorrhage Following Ocular Implantation of RPDS

Vladimir Bantseev; Giulio Barteselli; Chris Schuetz; Josh Horvath; Kristof Hovaten; Signe R Erickson; Jay M Stewart; Ellison Bentley; Paul E Miller; Brittney Dwyer; Jeffery J Prusakiewicz; T Michael Nork; Helen S Booler

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5929.

Physiology and Pharmacology August 2017

Evaluation of the Toxicity of Intravitreally Injected PLGA Microspheres and Rods in Monkeys and Rabbits: Effects of Depot Size on Inflammatory Response

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Evan A. Thackaberry; Cindy Farman; Fiona Zhong; Florence Lorget; Karin Staflin; Angelique Cercillieux; Paul E. Miller; Chris Schuetz; Debby Chang; Amin Famili; Ann L. Daugherty; Karthik Rajagopal; Vladimir Bantseev
TAGS: microspheres, oryctolagus cuniculus, rod photoreceptors, toxic effect, inflammatory response
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):4274-4285. https://doi.org/10.1167/iovs.16-21334

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

A Novel Perfusion System for Predicting Intraocular Ocular Drug Disposition In The Human Eye

Jeremy M Sivak; Darren Chan; Gah-Jone Won; Evan A Thackaberry; Vladimir Bantseev

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4453.

ARVO Annual Meeting Abstract June 2017

Determination of a No Observable Effect Level (NOEL) for Endotoxin following a Single Intravitreal Administration to Cynomolgus Macaques

Brian J Christian; Paul Miller; T Michael Nork; Carol A Rasmussen; Thomas Larsen; Evan A Thackaberry; Helen Booler; Vladimir Bantseev

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5164.

ARVO Annual Meeting Abstract June 2017

D-Arginine as a Novel Excipient Resulted in Retinal Degeneration Following Intravitreal Administration to Male New Zealand White Rabbits

Roxanne Andaya; Helen Booler; Charly Sioson; Vladimir Bantseev

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5183.

Anatomy and Pathology/Oncology March 2017

Determination of a No-Observable Effect Level for Endotoxin Following a Single Intravitreal Administration to Dutch Belted Rabbits

PDF

Vladimir Bantseev; Paul E. Miller; Ellison Bentley; Chris Schuetz; Tim M. Streit; Brian J. Christian; Cindy Farman; Helen Booler; Evan A. Thackaberry
TAGS: dutch, endotoxins, eye, intravitreal injections, no-observed-effect level, oryctolagus cuniculus
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1545-1552. https://doi.org/10.1167/iovs.16-21356

ARVO Annual Meeting Abstract June 2015

Characterization of the pH and Temperature in the Rabbit Vitreous: Key Parameters for the Development of Long Acting Delivery of Drugs to the Posterior Segment of the Eye

Florence LORGET; Chris Schuetz; Simon Authier; Michel Carrier; Audrey Parenteau; Ann Daughety; Vladimir Bantseev; Evan A. Thackaberry

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):146.

ARVO Annual Meeting Abstract June 2015

Determination of a No Observable Effect Level (NOEL) for Endotoxin following a Single Intravitreal Administration to Male Dutch Belted Rabbits

Tim Streit; Paul E. Miller; Ellison Bentley; Evan A. Thackaberry; Chris Schuetz; Peter Sonnentag; Cindy Farman; Brian J Christian; Vladimir Bantseev

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3368.

ARVO Annual Meeting Abstract April 2014

Development of Pseudophakic Model in Young Non-Human Primates

Ewa Budzynski; Vladimir Bantseev; Chris Schuetz; Fiona Zhong; Cindy Farman; Leandro B C Teixeira; Richard R Dubielzig; Michael Struck; Ellison Bentley; Evan Thackaberry

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1218.

ARVO Annual Meeting Abstract April 2011

Safety And Tolerability Of Retinostat®, A Lentiviral-vector Based Gene Therapy Product For The Treatment Of Wet Age-related Macular Degeneration, In Rabbits And Monkeys

Scott Ellis; Peter Widdowson; Katie Binley; T. Michael Nork; Paul Miller; Vlad Bantseev; Brian Christian; Kyriacos Mitrophanous; Stuart Naylor

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):488.

ARVO Annual Meeting Abstract April 2011

Anti-Factor D Fab: In vivo Effects Following Intravitreous Administration to Cynomolgus Monkeys

Vladimir Bantseev; Rebecca Erickson; Melissa Cheu; Caroline Amaya; Consuelo Alcalde; Yi Zhang; Joseph Beyer

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5657.

ARVO Annual Meeting Abstract April 2010

Spectral Domain OCT Segmentation Accuracy in Monkeys

K. B. McIntyre; C. A. Rasmussen; A. K. Goulding; V. Bantseev; J. N. Ver Hoeve; P. L. Kaufman; B. J. Christian; T. M. Nork

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):4401.

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OpRegen retinal pigment epithelial (RPE) cell therapy engrafts within the RPE of Gottingen mini-pigs by 4-weeks post-administration via subretinal delivery

Direct Tie2 Agonists Stabilize Vasculature for the Treatment of Diabetic Macular Edema

Determination of a No Observed Effect Level (NOEL) for Beta Glucans following a Single Intravitreal Administration to Female Dutch Belted Rabbits

Nonclinical toxicology and biocompatibility program supporting clinical development and registration of the Port Delivery System with ranibizumab

Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow

Functional and Ultrastructural Assessment of Novel OCT Findings in the Cynomolgus Monkey

In vivo Effects of CCFD9260S Following Intravitreal Administration to Cynomolgus Monkeys

The Presence of Protein in Formulation Ameliorates Retinal Changes Observed on OCT Following Intravitreal Administration of Hyperosmotic Solution in Cynomolgus Monkeys

Development of Minipigs Surgical Model: Cauterization of the Choroid Following Scleral Dissection Mitigates Risk of Post-Operative Vitreous Hemorrhage Following Ocular Implantation of RPDS

Evaluation of the Toxicity of Intravitreally Injected PLGA Microspheres and Rods in Monkeys and Rabbits: Effects of Depot Size on Inflammatory Response

A Novel Perfusion System for Predicting Intraocular Ocular Drug Disposition In The Human Eye

Determination of a No Observable Effect Level (NOEL) for Endotoxin following a Single Intravitreal Administration to Cynomolgus Macaques

D-Arginine as a Novel Excipient Resulted in Retinal Degeneration Following Intravitreal Administration to Male New Zealand White Rabbits

Determination of a No-Observable Effect Level for Endotoxin Following a Single Intravitreal Administration to Dutch Belted Rabbits

Characterization of the pH and Temperature in the Rabbit Vitreous: Key Parameters for the Development of Long Acting Delivery of Drugs to the Posterior Segment of the Eye

Determination of a No Observable Effect Level (NOEL) for Endotoxin following a Single Intravitreal Administration to Male Dutch Belted Rabbits

Development of Pseudophakic Model in Young Non-Human Primates

Safety And Tolerability Of Retinostat®, A Lentiviral-vector Based Gene Therapy Product For The Treatment Of Wet Age-related Macular Degeneration, In Rabbits And Monkeys

Anti-Factor D Fab: In vivo Effects Following Intravitreous Administration to Cynomolgus Monkeys

Spectral Domain OCT Segmentation Accuracy in Monkeys

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