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ARVO Annual Meeting Abstract June 2023

Suprachoroidal delivery of CLS-301, a potent small molecule integrin antagonist, offers multimonth durability and high bioavailability in the chorioretina

Viral Kansara; Leroy Muya; Thomas A Ciulla

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2611.

ARVO Annual Meeting Abstract June 2022

Targeting, Compartmentalization and Durability of Suprachoroidally Injected Small Molecule Suspensions in Multiple Preclinical Models

Viral Kansara; Leroy Muya; Cherry Wan; Shelley Hancock; Thomas A Ciulla

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4168 – F0160.

ARVO Annual Meeting Abstract June 2021

Suprachoroidally delivered DNA nanoparticles produce human Myosin7A protein in RPE-choroid in rabbits

Viral Kansara; Mark J Cooper; Leroy Muya; Robert Moen; Thomas A Ciulla

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1200.

ARVO Annual Meeting Abstract June 2021

Long-acting potential of suprachoroidally delivered BCX4161, a selective plasma kallikrein inhibitor, for diabetic macular edema

Leroy Muya; Yahya El-Kattan; Viral Kansara; Yarlagadda Babu; Thomas A Ciulla

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2194.

Articles June 2021

Evaluation of Long-Lasting Potential of Suprachoroidal Axitinib Suspension Via Ocular and Systemic Disposition in Rabbits

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Viral S. Kansara; Leroy W. Muya; Thomas A. Ciulla
TAGS: axitinib, oryctolagus cuniculus, subcutaneous injections, patient disposition, eye
Trans. Vis. Sci. Tech.. 2021; 10(7):19. https://doi.org/10.1167/tvst.10.7.19

Includes: Supplemental Content

Articles December 2020

Suprachoroidally Delivered DNA Nanoparticles Transfect Retina and Retinal Pigment Epithelium/Choroid in Rabbits

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Viral S. Kansara; Mark Cooper; Ozge Sesenoglu-Laird; Leroy Muya; Robert Moen; Thomas A. Ciulla

Trans. Vis. Sci. Tech.. 2020; 9(13):21. https://doi.org/10.1167/tvst.9.13.21

ARVO Annual Meeting Abstract June 2020

Ocular Pharmacokinetics and Safety of Suprachoroidal A01017, Small Molecule Complement Inhibitor, Injectable Suspension in Rabbits

Shelley E Hancock; Avinash Phadke; Viral Kansara; David Boyer; Jose Rivera; Christopher Marlor; Steven Podos; Jason Wiles; Rick McElheny; Thomas A Ciulla; Mingjun Huang; Mark Cartwright

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3694.

ARVO Annual Meeting Abstract June 2020

Suprachoroidal CLS-AX (axitinib injectable suspension), as a Potential Long-Acting Therapy for Neovascular Age-Related Macular Degeneration (nAMD)

Peter K Kaiser; Thomas Ciulla; Viral Kansara

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3977.

ARVO Annual Meeting Abstract June 2020

Pharmacokinetics and Ocular Tolerability of Suprachoroidal CLS-AX (axitinib injectable suspension) in rabbits

Leroy Muya; Viral Kansara; Thomas Ciulla

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4925.

ARVO Annual Meeting Abstract June 2020

Gene therapy biofactory: Mathematical modeling of pharmacokinetics

Lucia Carichino; Giovanna Guidoboni; Viral Kansara; Thomas Ciulla; Alon Harris

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2872.

ARVO Annual Meeting Abstract July 2019

Suprachoroidally delivered non-viral DNA nanoparticles transfect chorioretinal cells in non-human primates and rabbits

Viral Kansara; Jesse Yoo; Mark J Cooper; Ozge Sensenoglu Laird; Donna Taraborelli; Robert Moen; Glenn Noronha

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2909.

ARVO Annual Meeting Abstract July 2018

The hierarchy of pro-inflammatory cytokines in ocular inflammation

Xiaoqiu Wu; Andre Cunha; Qin Zhang; Melissa Prentiss; Vanessa Kainz; YongYao Xu; Joanna Vrouvlianis; Hui Li; Nalini Rangaswamy; Barrett Leehy; Terri McGee; Christie Bell; Chad E Bigelow; Viral Kansara; Qian Huang; Henry Wu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2532.

ARVO Annual Meeting Abstract July 2018

Inflammatory cytokines combined with hyperglycemia induces retinopathy phenotypes in Ins2 Akita mice

Melissa Prentiss; Joanna Vrouvlianis; Andre Cunha; Xiaoqiu Wu; Terri McGee; Timothy Drew; Rosemarie Cepeda; Qian Huang; Viral Kansara

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3544.

ARVO Annual Meeting Abstract September 2016

Non-invasive in vivo fluorescence imaging method enables ocular pharmacokinetics assessment of intravitreally administered biologics in rabbits

Viral Kansara; Debby Long; Timothy Drew; Farid Sari-Sarraf; Radhika Sharma; Hidetomo Imase; Qiying Hu; Bruce D Jaffee

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2209.

ARVO Annual Meeting Abstract September 2016

The Ins2 Akita diabetic mouse lacks advanced retinopathy complications

Melissa J Prentiss; Timothy Drew; Joanna Vrouvlianis; John Demirs; Hui Li; Natasha Buchanan; Bruce D Jaffee; Viral Kansara

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5427.

ARVO Annual Meeting Abstract March 2012

Activation of the Wnt Pathway in a Corneal Neovascularization Model

Sassan Azarian; Rosemarie Cepeda; Jun Liu; Shifeng Pan; Nicholas Ng; Bijan Etemad-Gilbertson; Shelby Giza; Jimmy Elliott; Viral Kansara; Bruce Jaffee

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2405.

ARVO Annual Meeting Abstract May 2008

Ocular Tissue Uptake of Mannitol and DiazepamFollowing Subconjunctival Injection

R. Gaudana; V. Kansara; Y. Hao; A. Mitra

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):1830.

ARVO Annual Meeting Abstract May 2007

Uptake Mechanism and Intracellular Regulation of Folic Acid in Human Retinoblastoma Cells: Role of High Affinity Folate Carrier Mediated System

Y. Hao; V. Kansara; D. Paturi; A. K. Mitra

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):47.

ARVO Annual Meeting Abstract May 2006

Administration of Anecortave Acetate in a Finite Element Physiologic Ocular Pharmacokinetic Model

A.L. Weiner; P.J. Missel; J.E. Chastain; Y. Yaacobi; A.K. Mitra; U.B. Kompella; V. Kansara; S. Duvvuri; A. Amrite; N. Cheruvu

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):5084.

ARVO Annual Meeting Abstract May 2006

A Role of Human Sodium Dependant Multivitamin Transporter (hSMVT) System for Biotin Uptake and Cellular Translocation in Human Derived Retinoblastoma Cells (Y–79)

V. Kansara; B. Balasubrahmanyam; N. Sabates; A. Mitra

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):3816.

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