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ARVO Annual Meeting Abstract June 2021

Macrophage Ontogeny and Distribution within the Conventional Outflow Tract

Katy Liu; Darren Schuman; Guorong Li; W. Daniel Stamer; Daniel R Saban

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2247. doi:

ARVO Annual Meeting Abstract June 2021

Identification of ESR1 in aqueous humor outflow pathway tissues

Hannah Youngblood; Jingwen Cai; Kristin Perkumas; Hongfang Yu; Michael A Hauser; W. Daniel Stamer; Yutao Liu

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1497. doi:

ARVO Annual Meeting Abstract June 2021

Chronic Oxidative Stress in Primary Retinal Pigmented Epithelium Monolayers Increases Basolateral Exosome Release and Changes Both Exosome and Extracellular Matrix Proteomes

Belinda Hernandez; Mikael Klingeborn; Nikolai Skiba; Daniel Grigsby; Una Kelly; Martha Caday; Arvydas Maminishkis; TeddiJo Watkins; Sheldon S Miller; W. Daniel Stamer; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):256. doi:

ARVO Annual Meeting Abstract June 2021

Vasoregulator Effects on Outflow Resistance, Flow Patterns and Distal Vessels in the Conventional Outflow Pathway of Mouse and Human Eyes

Fiona S McDonnell; Todd Fleming; Megan Kuhn; Heather Schmitt; Kristin Perkumas; Joseph van Batenburg-Sherwood; Alex S Huang; Darryl R Overby; Daniel W Stamer

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):469. doi:

ARVO Annual Meeting Abstract June 2021

Genetic susceptibility to Loxl1 knockout-induced elastosis in a mouse model

Heather Schmitt; TeddiJo Watkins; Kristyn Hake; Megan Kuhn; Guorong Li; Daniel W Stamer; Michael A Hauser

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):468. doi:

ARVO Annual Meeting Abstract June 2021

Elevated IOP stimulates NO-mediated IOP homeostasis in mice

Ester Reina Torres; Jason YH Chang; Joseph van Batenburg-Sherwood; Daniel W Stamer; Darryl R Overby

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2781. doi:

ARVO Annual Meeting Abstract June 2021

Calcium-Dependent Transcellular Pore Formation in Schlemm’s Canal Endothelial Cells

Jacques Bertrand; Daniel W Stamer; Darryl R Overby

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):484. doi:

ARVO Annual Meeting Abstract June 2021

LOXL1-AS1 regulates extracellular matrix remodeling, mechanotransduction responses, and cellular morphology in human outflow cells.

Kristyn Hake; Heather Schmitt; William Johnson; Maria Gomez-Caraballo; Kristin Perkumas; Michael A Hauser; Daniel W Stamer

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):558. doi:

ARVO Annual Meeting Abstract June 2021

Differential Responses of Human Juxtacanalicular and Trabecular Meshwork Beam Cells to Mechanical Stretch

Haven Roberts; Michael Lucio De Ieso; Daniel W Stamer

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):552. doi:

ARVO Annual Meeting Abstract June 2021

Differential effects of bimatoprost vs. bimatoprost free acid on outflow cell MMPs

Kristin Perkumas; Douglas J Rhee; Daniel W Stamer

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):551. doi:

ARVO Annual Meeting Abstract June 2021

Effects of phenylephrine on proximal and distal conventional outflow vessels in living animals

Guorong Li; Kevin Choy; Kristyn Hake; Sina Farsiu; C Ross Ethier; Daniel W Stamer

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):550. doi:

ARVO Annual Meeting Abstract June 2021

Role for Arg1 and Arg2 in Age-related Intraocular Pressure Homeostasis

Jingwen Cai; Hongfang Yu; Michelle Drewry; Daniel W Stamer; Robert W Caldwell; Ruth B Caldwell; Yutao Liu

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1492. doi:

ARVO Annual Meeting Abstract June 2021

TGFβ2 modulates YAP/TAZ activity in human trabecular meshwork cells through ERK and ROCK signaling pathways

Haiyan Li; Haven Roberts; Daniel W Stamer; Preethi S Ganapathy; Samuel Herberg

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1657. doi:

ARVO Annual Meeting Abstract June 2021

Targeting YAP/TAZ mechanoregulation with statins to reverse glaucomatous trabecular meshwork stiffening

Hannah Yoo; Haiyan Li; Ana N Strat; Haven Roberts; Daniel W Stamer; Alison Patteson; Robert W Weisenthal; Preethi S Ganapathy; Samuel Herberg

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1647. doi:

ARVO Annual Meeting Abstract June 2021

The Role of Thrombospondin-1 in Rho-kinase Inhibitor Mediated Changes in Outflow Facility

Sze Wan Shan; Chi-wai Do; Chuen Thomas Lam; Hoi Lam Li; Daniel W Stamer; Chi Ho To

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1631. doi:

ARVO Annual Meeting Abstract June 2021

Caveolin-1 mediates relaxation of trabecular meshwork cells to chronic mechanical stretch via protein kinase C

Michael Lucio De Ieso; Megan Kuhn; Michael H Elliott; Daniel W Stamer

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):467. doi:

Articles May 2021

Optogenetic Modulation of Intraocular Pressure in a Glucocorticoid-Induced Ocular Hypertension Mouse Model

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Tia J. Kowal; Philipp P. Prosseda; Ke Ning; Biao Wang; Jorge Alvarado; Brent E. Sendayen; Sayena Jabbehdari; W. Daniel Stamer; Yang Hu; Yang Sun
TAGS: dexamethasone, glucocorticoids, intraocular pressure, mice, ocular hypertension, oculocerebrorenal syndrome, optogenetics, eye
Trans. Vis. Sci. Tech.. 2021; 10(6):10. doi: https://doi.org/10.1167/tvst.10.6.10

Physiology and Pharmacology December 2020

A Small Molecule Inhibitor of VE-PTP Activates Tie2 in Schlemm's Canal Increasing Outflow Facility and Reducing Intraocular Pressure

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Guorong Li; Astrid F. Nottebaum; Mitchell Brigell; Iris D. Navarro; Ute Ipe; Sarthak Mishra; Maria Gomez-Caraballo; Heather Schmitt; Brandi Soldo; Steve Pakola; Barbara Withers; Kevin G. Peters; Dietmar Vestweber; W. Daniel Stamer

Invest. Ophthalmol. Vis. Sci.. 2020; 61(14):12. doi: https://doi.org/10.1167/iovs.61.14.12

Includes: Supplemental Content

Glaucoma November 2020

Reduced Oxidative Phosphorylation and Increased Glycolysis in Human Glaucoma Lamina Cribrosa Cells

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Khalid Kamel; Colm J. O'Brien; Alexander V. Zhdanov; Dmitri B. Papkovsky; Abbot F. Clark; W. Daniel Stamer; Mustapha Irnaten

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):4. doi: https://doi.org/10.1167/iovs.61.13.4

Physiology and Pharmacology September 2020

Physiologic Consequences of Caveolin-1 Ablation in Conventional Outflow Endothelia

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Michael L. De Ieso; Jami M. Gurley; Mark E. McClellan; Xiaowu Gu; Iris Navarro; Guorong Li; Maria Gomez-Caraballo; Eric Enyong; W. Daniel Stamer; Michael H. Elliott
TAGS: ablation, caveolins, endothelium, intraocular pressure, mice, nitric oxide synthase, body tissue, eye
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):32. doi: https://doi.org/10.1167/iovs.61.11.32

Includes: Supplemental Content

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Macrophage Ontogeny and Distribution within the Conventional Outflow Tract

Identification of ESR1 in aqueous humor outflow pathway tissues

Chronic Oxidative Stress in Primary Retinal Pigmented Epithelium Monolayers Increases Basolateral Exosome Release and Changes Both Exosome and Extracellular Matrix Proteomes

Vasoregulator Effects on Outflow Resistance, Flow Patterns and Distal Vessels in the Conventional Outflow Pathway of Mouse and Human Eyes

Genetic susceptibility to Loxl1 knockout-induced elastosis in a mouse model

Elevated IOP stimulates NO-mediated IOP homeostasis in mice

Calcium-Dependent Transcellular Pore Formation in Schlemm’s Canal Endothelial Cells

LOXL1-AS1 regulates extracellular matrix remodeling, mechanotransduction responses, and cellular morphology in human outflow cells.

Differential Responses of Human Juxtacanalicular and Trabecular Meshwork Beam Cells to Mechanical Stretch

Differential effects of bimatoprost vs. bimatoprost free acid on outflow cell MMPs

Effects of phenylephrine on proximal and distal conventional outflow vessels in living animals

Role for Arg1 and Arg2 in Age-related Intraocular Pressure Homeostasis

TGFβ2 modulates YAP/TAZ activity in human trabecular meshwork cells through ERK and ROCK signaling pathways

Targeting YAP/TAZ mechanoregulation with statins to reverse glaucomatous trabecular meshwork stiffening

The Role of Thrombospondin-1 in Rho-kinase Inhibitor Mediated Changes in Outflow Facility

Caveolin-1 mediates relaxation of trabecular meshwork cells to chronic mechanical stretch via protein kinase C

Optogenetic Modulation of Intraocular Pressure in a Glucocorticoid-Induced Ocular Hypertension Mouse Model

A Small Molecule Inhibitor of VE-PTP Activates Tie2 in Schlemm's Canal Increasing Outflow Facility and Reducing Intraocular Pressure

Reduced Oxidative Phosphorylation and Increased Glycolysis in Human Glaucoma Lamina Cribrosa Cells

Physiologic Consequences of Caveolin-1 Ablation in Conventional Outflow Endothelia

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