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ARVO Annual Meeting Abstract June 2024

Interspecies comparison of ocular pharmacokinetics of a dexamethasone implant

Kayla Rudeen; Valerie S Acuna; Robert Jewell; Werhner Orilla; Alireza Abdolvahabi; Vishard Ragoonanan; Mitalee Tamhane; Jie Shen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3160.

ARVO Annual Meeting Abstract July 2019

Intraocular pressure (IOP) lowering efficacy of Bimatoprost Sustained Release (BimSR) in dogs pretreated with selective laser trabeculoplasty (SLT)

Corine Ghosn; Michael Engles; Lakshmi Rajagopalan; Sveti Ugarte; Shruti Mistry; Werhner Orilla; Goodkin Margot; Michael R Robinson; Mohammed Dibas

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3779.

ARVO Annual Meeting Abstract July 2019

The effects of selective laser trabeculoplasty (SLT) in normotensive beagle dogs

Michael Engles; Corine Ghosn; Sveti Ugarte; Shruti Mistry; Werhner Orilla; Goodkin Margot; Mohammed Dibas; Michael R Robinson

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3796.

ARVO Annual Meeting Abstract July 2018

Intravitreal Brimonidine Drug Delivery System (Brimo DDS Generation 1) Enhances Spatial Sweep Visual Evoked Potential (sVEP) in a Non-human Primate Model of Chronic Glaucoma

James A Burke; Kai-Ming Zhang; Werhner Orilla; Corine Ghosn; Larry A Wheeler

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1246.

ARVO Annual Meeting Abstract July 2018

In Vivo Angiographic Study of Rabbit Aqueous Outflow following Ab Interno Gelatin Stent Implantation

Susan S Lee; Saumya Nagar; Lakshmi Rajagopalan; Werhner Orilla; Karl G Csaky; Alex Huang; Alexandra Almazan; James A Burke; Michael R Robinson

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1653.

ARVO Annual Meeting Abstract July 2018

Visualization of conjunctival lymphatic vessels in normotensive rabbits

Lakshmi Rajagopalan; Saumya Nagar; Werhner Orilla; Karl G Csaky; Alexandra Almazan; James A Burke; Michael R Robinson; Susan S Lee

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1654.

ARVO Annual Meeting Abstract July 2018

A Rabbit Model for Glaucoma Filtration Surgery

Saumya Nagar; Alexandra Almazan; Lakshmi Rajagopalan; Susan S Lee; Werhner Orilla; James A Burke; Michael R Robinson

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):492.

ARVO Annual Meeting Abstract June 2017

Interspecies Comparison of Small Molecule Distribution Into the Anterior Chamber Following Intravitreal Administration

Jennifer Seal; Werhner Orilla; Edward Chow; James A Burke; Jie Shen

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):439.

ARVO Annual Meeting Abstract June 2013

Ocular bioavailability of brimonidine 0.1% BID in non-human primates

Chinatsu Tosha; Sherri Decker; Guadalupe Ruiz; Octavio Avalos; Werhner Orilla; Larry Gruber; Ton Lin; Alexandra Almazan; Daniel Gil; James Burke

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5072.

Retina June 2011

Pharmacokinetics of a Sustained-Release Dexamethasone Intravitreal Implant in Vitrectomized and Nonvitrectomized Eyes

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Joan-En Chang-Lin; James A. Burke; Qing Peng; Ton Lin; Werhner C. Orilla; Corine R. Ghosn; Kai-Ming Zhang; Baruch D. Kuppermann; Michael R. Robinson; Scott M. Whitcup; Devin F. Welty
TAGS: dexamethasone, eye, implants, intravitreal implants, pharmacokinetics, vitrectomy, vitreous body, retina
Invest. Ophthalmol. Vis. Sci.. 2011; 52(7):4605-4609. https://doi.org/10.1167/iovs.10-6387

Physiology and Pharmacology May 2011

Treatment of Experimental Anterior and Intermediate Uveitis by a Dexamethasone Intravitreal Implant

PDF

Corine R. Ghosn; Yong Li; Werhner C. Orilla; Ton Lin; Larry Wheeler; James A. Burke; Michael R. Robinson; Scott M. Whitcup
TAGS: dexamethasone, eye, histopathology tests, implants, inflammation, inflammatory markers, intravitreal implants, uveitis, uveitis, intermediate, immune reconstitution inflammatory syndrome
Invest. Ophthalmol. Vis. Sci.. 2011; 52(6):2917-2923. https://doi.org/10.1167/iovs.10-5939

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2011

The Role Of Ocular Pigmentation In The Intraocular Pressure Response To Brimonidine In Rabbits

James A. Burke; Lupe Ruiz; Barbara Feldmann; Werhner Orilla; Corine Ghosn; Louis Lo; Jinsong NI; Jie Shen; Larry Wheeler

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2466.

Physiology and Pharmacology February 2011

Effects of Vitreous Liquefaction on the Intravitreal Distribution of Sodium Fluorescein, Fluorescein Dextran, and Fluorescent Microparticles

PDF

Lay Ean Tan; Werhner Orilla; Patrick M. Hughes; Susan Tsai; James A. Burke; Clive G. Wilson
TAGS: dextran, fluorescein, liquefaction, sodium fluorescein, vitreous body, cell-derived microparticles, hyaluronidase, angiogram
Invest. Ophthalmol. Vis. Sci.. 2011; 52(2):1111-1118. https://doi.org/10.1167/iovs.10-5813

ARVO Annual Meeting Abstract April 2010

Pharmacokinetics, Pharmacodynamics, and Visual Dissolution Rates of Three Forms of Triamcinolone Acetonide (TA) in Rabbits

R. Migon; T. Lin; L. Zacharias; C. Ghosn; W. Orilla; B. Feldmann; G. Ruiz; Y. Li; J. A. Burke; B. D. Kuppermann

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):4504.

ARVO Annual Meeting Abstract April 2009

Uveal Melanoma in a Non-Human Primate

M. Ramos; D. Albert; R. Dubielzig; A. Neekhra; S. Salamat; T. Lin; W. Orilla; Y. Li; J. Burke

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):3395.

ARVO Annual Meeting Abstract May 2008

Structural Changes Revealed by High Resolution OCT in a Monkey Model of Chronic Experimental Glaucoma

A. S. Vilupuru; K.-M. Zhang; T. Lin; G. Ruiz; B. Feldmann; W. Orilla; Y. Li; C. Ghosn; J. Burke

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):4640.

ARVO Annual Meeting Abstract May 2008

Dexamethasone in an Intravitreal Drug Delivery System (Posurdex®) Decreases Levels of Inflammatory Mediators in a Model of Experimental Uveitis

C. Ghosn; Y. Li; W. Orilla; T. Lin; L. Wheeler; S. Whitcup; J. Burke

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):5632.

ARVO Annual Meeting Abstract May 2008

Transient Ocular Hypertension Results in Persistent Retinal Structural and Functional Changes in Pigmented Rabbits

G. Ruiz; K.-M. Zhang; A. S. Vilupuru; B. Feldmann; W. Orilla; T. Lin; C. Spada; M. Escobar; C. Ghosn; J. Burke

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):718.

ARVO Annual Meeting Abstract May 2008

A Functional and Anatomical Evaluation of Chronic BRVO in Primates

J. A. Burke; K.-M. Zhang; T. Lin; Y. Li; M. Escobar; W. Orilla; C. Ghosn; L. Wheeler

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):2696.

ARVO Annual Meeting Abstract May 2007

The Efficacy of Posurdex® (Dexamethasone in a Slow Release Biodegradable Device), in the Treatment of Experimental Anterior Uveitis

C. Ghosn; Y. Li; W. Orilla; T. Lin; N. Linke; B. DeBrosse; M. Robinson; L. Wheeler; S. Whitcup; J. Burke

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):5154.

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Interspecies comparison of ocular pharmacokinetics of a dexamethasone implant

Intraocular pressure (IOP) lowering efficacy of Bimatoprost Sustained Release (BimSR) in dogs pretreated with selective laser trabeculoplasty (SLT)

The effects of selective laser trabeculoplasty (SLT) in normotensive beagle dogs

Intravitreal Brimonidine Drug Delivery System (Brimo DDS Generation 1) Enhances Spatial Sweep Visual Evoked Potential (sVEP) in a Non-human Primate Model of Chronic Glaucoma

In Vivo Angiographic Study of Rabbit Aqueous Outflow following Ab Interno Gelatin Stent Implantation

Visualization of conjunctival lymphatic vessels in normotensive rabbits

A Rabbit Model for Glaucoma Filtration Surgery

Interspecies Comparison of Small Molecule Distribution Into the Anterior Chamber Following Intravitreal Administration

Ocular bioavailability of brimonidine 0.1% BID in non-human primates

Pharmacokinetics of a Sustained-Release Dexamethasone Intravitreal Implant in Vitrectomized and Nonvitrectomized Eyes

Treatment of Experimental Anterior and Intermediate Uveitis by a Dexamethasone Intravitreal Implant

The Role Of Ocular Pigmentation In The Intraocular Pressure Response To Brimonidine In Rabbits

Effects of Vitreous Liquefaction on the Intravitreal Distribution of Sodium Fluorescein, Fluorescein Dextran, and Fluorescent Microparticles

Pharmacokinetics, Pharmacodynamics, and Visual Dissolution Rates of Three Forms of Triamcinolone Acetonide (TA) in Rabbits

Uveal Melanoma in a Non-Human Primate

Structural Changes Revealed by High Resolution OCT in a Monkey Model of Chronic Experimental Glaucoma

Dexamethasone in an Intravitreal Drug Delivery System (Posurdex®) Decreases Levels of Inflammatory Mediators in a Model of Experimental Uveitis

Transient Ocular Hypertension Results in Persistent Retinal Structural and Functional Changes in Pigmented Rabbits

A Functional and Anatomical Evaluation of Chronic BRVO in Primates

The Efficacy of Posurdex® (Dexamethasone in a Slow Release Biodegradable Device), in the Treatment of Experimental Anterior Uveitis

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