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ARVO Annual Meeting Abstract June 2022

Characterization of cone structure and function in a mouse model for blue cone monochromacy patients with a C203R mutation

Emily Sechrest; Xiajie Ma; Wen-Tao Deng

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1789 – F0338. doi:

ARVO Annual Meeting Abstract June 2021

Disease mechanisms of X-linked cone dystrophy caused by missense mutations in the red and green cone opsins

Wen-Tao Deng; Ping Zhu; Frank M Dyka; Wolfgang Baehr; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1554. doi:

ARVO Annual Meeting Abstract June 2020

Rescue of cone structure and function in Opn1mw/sw double knockout mice

Wen-Tao Deng; Ping Zhu; Tiffanie Dahl; Wolfgang Baehr; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2456. doi:

Retina August 2019

Rescue of M-cone Function in Aged Opn1mw −/− Mice, a Model for Late-Stage Blue Cone Monochromacy

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Wen-Tao Deng; Jie Li; Ping Zhu; Beau Freedman; W. Clay Smith; Wolfgang Baehr; William W. Hauswirth
TAGS: gene therapy, mice, retinal cone, opsin
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3644-3651. doi: https://doi.org/10.1167/iovs.19-27079

ARVO Annual Meeting Abstract July 2019

Successful rescue of M-cone function in aged M-opsin knock-out mice, a model for blue cone monochromacy

Wen-Tao Deng; Jie Li; Ping Zhu; Wolfgang Baehr; William Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3419. doi:

ARVO Annual Meeting Abstract September 2016

Gene therapy in the Opn1mw Knock-out mouse, a model for blue cone monochromacy, leads to long-term M-cone restoration

Ji-Jing Pang; Yuxin Zhang; Ping Zhu; Wen-Tao Deng; Jie Li; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1166. doi:

ARVO Annual Meeting Abstract September 2016

Long term restoration of cone function following AAV-mediated gene therapy in CNGA3 -/- Nrl -/- Mice

Yuxin Zhang; Wei Du; Ping Zhu; Jie Li; Wen-Tao Deng; Chen Zhao; William Hauswirth; Ji-Jing Pang

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1175. doi:

Retina October 2015

Pathological Effects of Mutant C1QTNF5 (S163R) Expression in Murine Retinal Pigment Epithelium

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Astra Dinculescu; Seok-Hong Min; Frank M. Dyka; Wen-Tao Deng; Rachel M. Stupay; Vince Chiodo; W. Clay Smith; William W. Hauswirth
TAGS: antibodies, eye, immunohistochemistry, injections, mice, photoreceptors, proteins, retinal pigment epithelium, spatial vectors, tissue membrane
Invest. Ophthalmol. Vis. Sci.. 2015; 56(11):6971-6980. doi: https://doi.org/10.1167/iovs.15-17166

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Localization of Clarin-1 in Photoreceptor Cells and Optimized AAV Gene Delivery of Clarin-1 to the Mouse Retina

William W Hauswirth; Rachel M Stupay; Ping Zhu; Wen-Tao Deng; Vince Chiodo; Sanford L Boye; Qiuhong Li; Astra Dinculescu

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3630. doi:

ARVO Annual Meeting Abstract June 2015

AAV-mediated Long Term Rescue of Cone Function in the CNGA3 -/- Nrl -/- Mice Following Intravitreal Injection

Yuxin Zhang; Wei Du; Ping Zhu; Jie Li; Wen-Tao Deng; Sanford L Boye; Xi-Qin Ding; Shannon Elizabeth Boye; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5468. doi:

ARVO Annual Meeting Abstract April 2014

AAV-mediated Gene Therapy Restores Cone Function in the Cnga3/Nrl Double Knockout Mouse following intravitreous injection

Ji-Jing Pang; Ye Tao; Wei Du; Sanford L Boye; Jie Li; Wen-tao Deng; William W Hauswirth; Shannon Boye

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3317. doi:

ARVO Annual Meeting Abstract April 2014

AAV-mediated Gene Therapy Restores M-Cone Function in S-opsin only Thrb Knockout Mouse

Wei Du; Wen-tao Deng; Sanford L Boye; Jie Li; Wei Li; William W Hauswirth; Ji-Jing Pang

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3318. doi:

ARVO Annual Meeting Abstract April 2014

Optimization of Clarin-1 AAV Gene Delivery Vectors to the Mouse Retina

Rachel M Stupay; Ping Zhu; Wen-tao Deng; Vince Chiodo; Sanford L Boye; Qiuhong Li; William W Hauswirth; Astra Dinculescu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3324. doi:

ARVO Annual Meeting Abstract April 2014

The neuroprotection of Angiotensin-(1-7) in Tg(RHO P347S) and rd10 mice

Ping Zhu; Pollob Kumar Shil; Wen-tao Deng; Jie Li; Amrisha Verma; Tuhina Prasad; Qiuhong Li

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6187. doi:

Retina March 2014

AAV-Mediated Lysophosphatidylcholine Acyltransferase 1 ( Lpcat1 ) Gene Replacement Therapy Rescues Retinal Degeneration in rd11 Mice

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Xufeng Dai; Juanjuan Han; Yan Qi; Hua Zhang; Lue Xiang; Jineng Lv; Jie Li; Wen-Tao Deng; Bo Chang; William W. Hauswirth; Ji-jing Pang
TAGS: gene therapy, mice, retinal degeneration, eye, 1-acylglycerophosphocholine o-acyltransferase, did not receive therapy or drug, retinal cone, retina
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1724-1734. doi: https://doi.org/10.1167/iovs.13-13654

ARVO Annual Meeting Abstract June 2013

AAV-mediated Lpcat1 gene replacement therapy rescues retinal degeneration in rd11 mice

Xufeng Dai; Juanjuan Han; Zi-Bing Jin; Yan Qi; Jie Li; Wen-Tao Deng; Bo Chang; William Hauswirth; Ji-Jing Pang

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2715. doi:

ARVO Annual Meeting Abstract June 2013

AAV-mediated gene therapy restores cone function in the Cnga3/Nrl double knockout mouse

Ji-Jing Pang; Ye Tao; Sanford Boye; Jie Li; Wen-Tao Deng; Xi-Qin Ding; Stylianos Michalakis; Martin Biel; Shannon Boye; William Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2723. doi:

ARVO Annual Meeting Abstract June 2013

A retinal phenotype in Usher IIIA mouse models

Rachel Stupay; W Clay Smith; Wen-Tao Deng; Ping Zhu; William Hauswirth; Astra Dinculescu

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):298. doi:

ARVO Annual Meeting Abstract June 2013

CTRP5 over-expression in RPE cells leads to loss of RPE cell adhesion and retinal degeneration in wild-type mice

Astra Dinculescu; Seok-Hong Min; Wen-Tao Deng; Jie Li; Renee Ryals; Rachel Stupay; Ping Zhu; Bhubanananda Sahu; Radha Ayyagari; William Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4594. doi:

Retina April 2012

Tyrosine-Mutant AAV8 Delivery of Human MERTK Provides Long-Term Retinal Preservation in RCS Rats

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Wen-Tao Deng; Astra Dinculescu; Qiuhong Li; Sanford L. Boye; Jie Li; Marina S. Gorbatyuk; Jijing Pang; Vince A. Chiodo; Michael T. Matthes; Douglas Yasumura; Li Liu; Fowzan S. Alkuraya; Kang Zhang; Douglas Vollrath; Matthew M. LaVail; William W. Hauswirth
TAGS: eye, mertk gene, rats, tyrosine, retina, photoreceptors, spatial vectors, did not receive therapy or drug
Invest. Ophthalmol. Vis. Sci.. 2012; 53(4):1895-1904. doi: https://doi.org/10.1167/iovs.11-8831

Includes: Supplemental Content

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Characterization of cone structure and function in a mouse model for blue cone monochromacy patients with a C203R mutation

Disease mechanisms of X-linked cone dystrophy caused by missense mutations in the red and green cone opsins

Rescue of cone structure and function in Opn1mw/sw double knockout mice

Rescue of M-cone Function in Aged Opn1mw −/− Mice, a Model for Late-Stage Blue Cone Monochromacy

Successful rescue of M-cone function in aged M-opsin knock-out mice, a model for blue cone monochromacy

Gene therapy in the Opn1mw Knock-out mouse, a model for blue cone monochromacy, leads to long-term M-cone restoration

Long term restoration of cone function following AAV-mediated gene therapy in CNGA3 -/- Nrl -/- Mice

Pathological Effects of Mutant C1QTNF5 (S163R) Expression in Murine Retinal Pigment Epithelium

Localization of Clarin-1 in Photoreceptor Cells and Optimized AAV Gene Delivery of Clarin-1 to the Mouse Retina

AAV-mediated Long Term Rescue of Cone Function in the CNGA3 -/- Nrl -/- Mice Following Intravitreal Injection

AAV-mediated Gene Therapy Restores Cone Function in the Cnga3/Nrl Double Knockout Mouse following intravitreous injection

AAV-mediated Gene Therapy Restores M-Cone Function in S-opsin only Thrb Knockout Mouse

Optimization of Clarin-1 AAV Gene Delivery Vectors to the Mouse Retina

The neuroprotection of Angiotensin-(1-7) in Tg(RHO P347S) and rd10 mice

AAV-Mediated Lysophosphatidylcholine Acyltransferase 1 ( Lpcat1 ) Gene Replacement Therapy Rescues Retinal Degeneration in rd11 Mice

AAV-mediated Lpcat1 gene replacement therapy rescues retinal degeneration in rd11 mice

AAV-mediated gene therapy restores cone function in the Cnga3/Nrl double knockout mouse

A retinal phenotype in Usher IIIA mouse models

CTRP5 over-expression in RPE cells leads to loss of RPE cell adhesion and retinal degeneration in wild-type mice

Tyrosine-Mutant AAV8 Delivery of Human MERTK Provides Long-Term Retinal Preservation in RCS Rats

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