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ARVO Annual Meeting Abstract June 2025

Moxifloxacin release from polycaprolactone microneedles for ocular drug delivery

Yongdeok Jo; William F Mieler; Jennifer J Kang-Mieler

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5989.

ARVO Annual Meeting Abstract June 2025

Profiling the molecular landscape of the anti-VEGF target cell type in patients with proliferative diabetic retinopathy

Maximilian McCann; Basma Baccouche; Yueru Li; Priti Roy; Neil Sheth; Jennifer I Lim; William F Mieler; Felix Y Chau; Lawrence Joseph Ulanski; R.V. Paul Chan; Monique Monroe; Robert A Hyde; Michael Heiferman; Caitlin Berek; Anna Ong; Sudeshna De; Barbara Kitajewski; Ru-ik Chee; Yannek Isaac Leiderman; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):6333.

ARVO Annual Meeting Abstract June 2025

Fluorescein videoangiography-extracted retinal vascular permeability of diabetic subjects with no diabetic retinopathy (DMnoDR) and with mild non-proliferative diabetic retinopathy follow-up assessment

Sarah Rose Vavrek; Nicole Decker; Amani A Fawzi; William F Mieler; Kenneth Tichauer; Jennifer J Kang-Mieler

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4760.

ARVO Annual Meeting Abstract June 2025

Comparative Outcomes of Combined Phacovitrectomy for Proliferative Diabetic Retinopathy: Vitreous Hemorrhage vs. Traction Retinal Detachment

Yanliang li; Talisa E de Carlo Forest; Elmer Y Tu; William F Mieler

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2262.

ARVO Annual Meeting Abstract June 2025

Clinical Characteristics and Treatment Outcomes of Breakthrough Vitreous Hemorrhage in Peripheral Exudative Hemorrhagic Chorioretinopathy

Thanaporn Kritfuangfoo; William F Mieler; Yanliang li

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2257.

ARVO Annual Meeting Abstract June 2025

Improved visual and anatomic outcomes after surgery for proliferative sickle cell retinopathy

Jennifer I Lim; Hesham Gabr; Yannek Isaac Leiderman; Felix Y Chau; William F Mieler

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3257.

Retina June 2025

Treatment Efficacy of a Dual Release of Aflibercept and Dexamethasone From a Single Hydrogel Drug Delivery System in a Rodent Model

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Kayla M. Rudeen; Chryssa M. Maloney; Katherine L. Lydon; Leandro B. C. Teixeria; William F. Mieler; Jennifer J. Kang-Mieler
TAGS: aflibercept, choroidal neovascularization, dexamethasone, drug delivery systems, hydrogel, rodentia, treatment effectiveness, electroretinography, lasers, intraocular pressure
Trans. Vis. Sci. Tech.. 2025; 14(6):31. https://doi.org/10.1167/tvst.14.6.31

ARVO Annual Meeting Abstract June 2024

A one-year follow-up of retinal vascular permeability extracted from fluorescein videoangiographies (FVA) of diabetic subjects with no diabetic retinopathy (DMnoDR)

Sarah Rose Vavrek; Nicole Decker; Yanliang li; Amani A Fawzi; William F Mieler; Kenneth M. Tichauer; Jennifer J Kang-Mieler

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1753.

ARVO Annual Meeting Abstract June 2024

Combined Phacovitrectomy: Evaluating Clinical and Anatomic Outcomes in Vitreoretinal Diseases with Macular Indications

William F Mieler; Talisa E De Carlo; Elmer Y. Tu; Yanliang li

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4025.

ARVO Annual Meeting Abstract June 2024

Combined Phacovitrectomy Surgery in Proliferative Diabetic Retinopathy: Clinical Outcomes and Complication Rates

Yanliang li; Talisa E De Carlo; Elmer Y. Tu; William F Mieler

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4004.

ARVO Annual Meeting Abstract June 2023

Retinal vascular permeability as a preclinical biomarker for diabetic retinopathy

Sarah Vavrek; Elif Nalbant; Nicholas Konopek; Ghazi Bou Ghanem; Amani A Fawzi; William F Mieler; Kenneth Tichauer; Jennifer J Kang-Mieler

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):942.

ARVO Annual Meeting Abstract June 2023

Long-term safety and biocompatibility of a biodegradable, thermoresponsive aflibercept-loaded microsphere-hydrogel drug delivery system in nonhuman primates

Brett D Story; Sangwan Park; Karolina Roszak; Jaeho Shim; Monica Motta; Michelle Ferneding; Kayla M Rudeen; Glenn Yiu; William F Mieler; Sara M Thomasy; Jennifer J Kang-Mieler

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):737.

ARVO Annual Meeting Abstract June 2022

The influence of ultra-wide field fluorescein angiography on the diagnosis and management of diabetic retinopathy

Tala Al-Khaled; Nicole K Scripsema; Rawan Allozi Rupnow; Aziz A Khanifar; Thanos Papakostas; Christina Y. Weng; Ronald C Gentile; J. Peter Campbell; Jessica Lee; Felix Y. Chau; William F Mieler; Meenakashi Gupta; Amani A Fawzi; Judy E Kim; Jennifer I Lim; Robison Vernon Paul Chan

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1149.

ARVO Annual Meeting Abstract June 2021

Treatment Efficacy of Dual Release of Aflibercept and Dexamethasone from a Single Hydrogel Drug Delivery System in a Laser-induced Choroidal Neovascularization Model

Kayla Rudeen; Wenqiang Liu; Katherine L. Lydon; Sabrina J.K. Derwent; William F Mieler; Jennifer J Kang-Mieler

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):277.

Articles October 2020

Treatment Efficacy and Biocompatibility of a Biodegradable Aflibercept-Loaded Microsphere-Hydrogel Drug Delivery System

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Wenqiang Liu; Anessa Puskar Tawakol; Kayla M. Rudeen; William F. Mieler; Jennifer J. Kang-Mieler
TAGS: aflibercept, biocompatibility, choroidal neovascularization, drug delivery systems, hydrogel, injections, microspheres, treatment effectiveness, electroretinography, histopathology tests
Trans. Vis. Sci. Tech.. 2020; 9(11):13. https://doi.org/10.1167/tvst.9.11.13

ARVO Annual Meeting Abstract June 2020

Safety and Biocompatibility of a Biodegradable Microsphere-Hydrogel Drug Delivery System in Long-Evans Rats

Jennifer J Kang-Mieler; Wenqiang Liu; Anessa Puskar Tawakol; Kayla Rudeen; William F Mieler

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):322a.

ARVO Annual Meeting Abstract June 2020

Compartmental Model Analysis of Vitreal Drug Concentrations Following Administration of a Sustained Release Drug Delivery System

Emily Dosmar; Garet James Bailey; William F Mieler; Jennifer J Kang-Mieler

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2903.

Articles February 2020

Safety and Biocompatibility of Aflibercept-Loaded Microsphere Thermo-Responsive Hydrogel Drug Delivery System in a Nonhuman Primate Model

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Soohyun Kim; Jennifer J. Kang-Mieler; Wenqiang Liu; Zhe Wang; Glenn Yiu; Leandro B. C. Teixeira; William F. Mieler; Sara M. Thomasy
TAGS: aflibercept, hydrogel, microspheres, drug delivery systems, injections, primates
Trans. Vis. Sci. Tech.. 2020; 9(3):30. https://doi.org/10.1167/tvst.9.3.30

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Characterization of the Controlled and Extended Release of Dexamethasone-Loaded Nanoparticles and Aflibercept-Loaded Microspheres from a Hydrogel Drug Delivery System

Kayla Cascarilla; Wenqiang Liu; Anessa Puskar; Syed Hussain; William F Mieler; Jennifer J Kang-Mieler

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2985.

ARVO Annual Meeting Abstract July 2019

Study of Stability and Bioactivity of Aflibercept During Fabrication and Release from a Microsphere-Hydrogel Drug Delivery System

Wenqiang Liu; Kayla Cascarilla; Xi Li; Anessa Puskar; Syed Hussain; Shailee Shah; Bao-shiang Lee; William F Mieler; Jennifer J Kang-Mieler

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2987.

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Moxifloxacin release from polycaprolactone microneedles for ocular drug delivery

Profiling the molecular landscape of the anti-VEGF target cell type in patients with proliferative diabetic retinopathy

Fluorescein videoangiography-extracted retinal vascular permeability of diabetic subjects with no diabetic retinopathy (DMnoDR) and with mild non-proliferative diabetic retinopathy follow-up assessment

Comparative Outcomes of Combined Phacovitrectomy for Proliferative Diabetic Retinopathy: Vitreous Hemorrhage vs. Traction Retinal Detachment

Clinical Characteristics and Treatment Outcomes of Breakthrough Vitreous Hemorrhage in Peripheral Exudative Hemorrhagic Chorioretinopathy

Improved visual and anatomic outcomes after surgery for proliferative sickle cell retinopathy

Treatment Efficacy of a Dual Release of Aflibercept and Dexamethasone From a Single Hydrogel Drug Delivery System in a Rodent Model

A one-year follow-up of retinal vascular permeability extracted from fluorescein videoangiographies (FVA) of diabetic subjects with no diabetic retinopathy (DMnoDR)

Combined Phacovitrectomy: Evaluating Clinical and Anatomic Outcomes in Vitreoretinal Diseases with Macular Indications

Combined Phacovitrectomy Surgery in Proliferative Diabetic Retinopathy: Clinical Outcomes and Complication Rates

Retinal vascular permeability as a preclinical biomarker for diabetic retinopathy

Long-term safety and biocompatibility of a biodegradable, thermoresponsive aflibercept-loaded microsphere-hydrogel drug delivery system in nonhuman primates

The influence of ultra-wide field fluorescein angiography on the diagnosis and management of diabetic retinopathy

Treatment Efficacy of Dual Release of Aflibercept and Dexamethasone from a Single Hydrogel Drug Delivery System in a Laser-induced Choroidal Neovascularization Model

Treatment Efficacy and Biocompatibility of a Biodegradable Aflibercept-Loaded Microsphere-Hydrogel Drug Delivery System

Safety and Biocompatibility of a Biodegradable Microsphere-Hydrogel Drug Delivery System in Long-Evans Rats

Compartmental Model Analysis of Vitreal Drug Concentrations Following Administration of a Sustained Release Drug Delivery System

Safety and Biocompatibility of Aflibercept-Loaded Microsphere Thermo-Responsive Hydrogel Drug Delivery System in a Nonhuman Primate Model

Characterization of the Controlled and Extended Release of Dexamethasone-Loaded Nanoparticles and Aflibercept-Loaded Microspheres from a Hydrogel Drug Delivery System

Study of Stability and Bioactivity of Aflibercept During Fabrication and Release from a Microsphere-Hydrogel Drug Delivery System

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