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Articles January 2021

Optical Coherence Tomography Artifacts Are Associated With Adaptive Optics Scanning Light Ophthalmoscopy Success in Achromatopsia

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Katie M. Litts; Erica N. Woertz; Michalis Georgiou; Emily J. Patterson; Byron L. Lam; Gerald A. Fishman; Mark E. Pennesi; Christine N. Kay; William W. Hauswirth; Michel Michaelides; Joseph Carroll

Trans. Vis. Sci. Tech.. 2021; 10(1):11. doi: https://doi.org/10.1167/tvst.10.1.11

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology July 2020

XIAP Protects Retinal Ganglion Cells in the Mutant ND4 Mouse Model of Leber Hereditary Optic Neuropathy

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Sarah J. Wassmer; Yves De Repentigny; Derek Sheppard; Pamela S. Lagali; Lijun Fang; Stuart G. Coupland; Rashmi Kothary; John Guy; William W. Hauswirth; Catherine Tsilfidis
TAGS: birc4 gene, gene therapy, mice, optic atrophy, hereditary, leber, axon, retinal ganglion cells, optic nerve
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):49. doi: https://doi.org/10.1167/iovs.61.8.49

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Rescue of cone structure and function in Opn1mw/sw double knockout mice

Wen-Tao Deng; Ping Zhu; Tiffanie Dahl; Wolfgang Baehr; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2456. doi:

ARVO Annual Meeting Abstract June 2020

Development of an Allele-Independent Gene Replacement Therapy for Best Vitelliform Macular Dystrophy Using RNAi Technology

Brianna Bowman Young; Karina E Guziewicz; Alfred S Lewin; william W hauswirth; Cristhian Ildefonso

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2457. doi:

ARVO Annual Meeting Abstract June 2020

Serotype dependent Adeno-Associated Virus Hybrid Vector mediated gene therapy for Stargardt Disease

Frank M Dyka; Vince A. Chiodo; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2464. doi:

ARVO Annual Meeting Abstract June 2020

An Allele-Independent Gene Therapy Strategy Induces Rod Function in a Transgenic Swine Model of Autosomal Dominant Retinitis Pigmentosa

archana jalligampala; James Fransen; Jennifer Noel; Gobinda Pangeni; Maha Haleem Jabbar; William W Hauswirth; Alfred S Lewin; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4484. doi:

ARVO Annual Meeting Abstract June 2020

Optical coherence tomography artifacts predict adaptive optics scanning light ophthalmoscopy success in achromatopsia

Katie M Litts; Erica N. Woertz; Rachel E Linderman; Byron L Lam; Gerald A Fishman; Mark E Pennesi; Christine N Kay; William W Hauswirth; Joseph Carroll

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5271. doi:

Retina August 2019

Rescue of M-cone Function in Aged Opn1mw −/− Mice, a Model for Late-Stage Blue Cone Monochromacy

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Wen-Tao Deng; Jie Li; Ping Zhu; Beau Freedman; W. Clay Smith; Wolfgang Baehr; William W. Hauswirth
TAGS: gene therapy, mice, retinal cone, opsin
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3644-3651. doi: https://doi.org/10.1167/iovs.19-27079

ARVO Annual Meeting Abstract July 2019

Safety and long-term efficacy of AAV2- BEST1 gene augmentation therapy in canine model of Best vitelliform macular dystrophies

Karina E Guziewicz; Artur V Cideciyan; Brian T. Kendrick; Valerie L Dufour; Gordon Ruthel; Andras M Komaromy; Simone Iwabe; William Hauswirth; William A Beltran; Samuel G Jacobson; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5200. doi:

ARVO Annual Meeting Abstract July 2019

VMD2 Promoter-mediated Gene Therapy Optimizes Active Rap1a Expression in the Retinal Pigment Epithelium of Wild Type Mice

Haibo Wang; Aniket Ramshekar; Eric Kunz; William Hauswirth; M Elizabeth Hartnett

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1925. doi:

ARVO Annual Meeting Abstract July 2019

Dual Adeno-Associated Virus Vector mediated gene therapy for autosomal recessive Stargardt Disease

Frank M Dyka; Laurie L Molday; Vince A Chiodo; Robert S Molday; William Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3402. doi:

ARVO Annual Meeting Abstract July 2019

Successful rescue of M-cone function in aged M-opsin knock-out mice, a model for blue cone monochromacy

Wen-Tao Deng; Jie Li; Ping Zhu; Wolfgang Baehr; William Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3419. doi:

ARVO Annual Meeting Abstract July 2018

Long-term preservation of photoreceptor function and structure following early-stage treatment by AAV-mediated gene augmentation in canine model of NPHP5 Leber congenital amaurosis

Gustavo D Aguirre; Artur V Cideciyan; Sanford L Boye; Simone Iwabe; Valerie Dufour; Malgorzata Swider; Karolina Roszak; William W Hauswirth; Samuel G Jacobson; William A Beltran

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6006. doi:

ARVO Annual Meeting Abstract July 2018

Neuroprotection by overexpression of transcription factor Max in experimental glaucoma.

Rafael Lani; Mariana Santana Dias; Tabata Granja Araujo; William W Hauswirth; Adalmir Morterá Dantas; Mario Fiorani Junior; Hilda Petrs Silva; Rafael Linden

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6137. doi:

ARVO Annual Meeting Abstract July 2018

Interocular symmetry of foveal cone topography in achromatopsia (ACHM)

Katie M Litts; Christopher S Langlo; Emily J Patterson; Rebecca Mastey; Jenna A Cava; Patrick May; Byron L Lam; Gerald A Fishman; Mark E Pennesi; Christine N. Kay; Alfredo Dubra; William W Hauswirth; Kathleen N Beasley; Jeffrey D Chulay; Joseph Carroll

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4992. doi:

ARVO Annual Meeting Abstract July 2018

Very long chain ceramides production mediated by ELOVL4 stabilizes tight junctions and prevents diabetes-induced retinal vascular permeability

Julia V Busik; Nermin Kady; Xuwen Liu; Todd Lydic; Sergey S Seregin; Andrea Amalfitano; Vince A Chiodo; Sanford L Boye; William W Hauswirth; David A Antonetti

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3002. doi:

ARVO Annual Meeting Abstract July 2018

Phenotypic consequences of amino acid substitutions at the S163 position in C1QTNF5 protein following expression in murine RPE

Astra Dinculescu; Susan Bolch; Frank M Dyka; Manoj Kulkarni; Chiab Simpson; W Clay Smith; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3052. doi:

ARVO Annual Meeting Abstract July 2018

The expression pattern and pathological effects of CLRN1 mutant proteins in the mouse retina

Susan Bolch; Frank M Dyka; Manoj Kulkarni; Rachel Stupay; Chiab Simpson; W Clay Smith; William W Hauswirth; Astra Dinculescu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3053. doi:

ARVO Annual Meeting Abstract July 2018

Assessment of cone outer segment defects and rescue in the Opn1mw/sw double knockout mouse

Tiffanie M. Dahl; Michelle Reed; Cecilia D. Gerstner; Guoxin Ying; Wentao Deng; William W Hauswirth; Wolfgang Baehr

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3054. doi:

ARVO Annual Meeting Abstract July 2018

BEST1 gene augmentation therapy corrects light-modulated retinal micro-detachments

Karina E Guziewicz; Artur V Cideciyan; William A Beltran; Andras M Komaromy; Valerie Dufour; Malgorzata Swider; Simone Iwabe; Alexander Sumaroka; Brian T Kendrick; Gordon Ruthel; Vince A Chiodo; Elise Heon; William W Hauswirth; Samuel G Jacobson; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4522. doi:

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Optical Coherence Tomography Artifacts Are Associated With Adaptive Optics Scanning Light Ophthalmoscopy Success in Achromatopsia

XIAP Protects Retinal Ganglion Cells in the Mutant ND4 Mouse Model of Leber Hereditary Optic Neuropathy

Rescue of cone structure and function in Opn1mw/sw double knockout mice

Development of an Allele-Independent Gene Replacement Therapy for Best Vitelliform Macular Dystrophy Using RNAi Technology

Serotype dependent Adeno-Associated Virus Hybrid Vector mediated gene therapy for Stargardt Disease

An Allele-Independent Gene Therapy Strategy Induces Rod Function in a Transgenic Swine Model of Autosomal Dominant Retinitis Pigmentosa

Optical coherence tomography artifacts predict adaptive optics scanning light ophthalmoscopy success in achromatopsia

Rescue of M-cone Function in Aged Opn1mw −/− Mice, a Model for Late-Stage Blue Cone Monochromacy

Safety and long-term efficacy of AAV2- BEST1 gene augmentation therapy in canine model of Best vitelliform macular dystrophies

VMD2 Promoter-mediated Gene Therapy Optimizes Active Rap1a Expression in the Retinal Pigment Epithelium of Wild Type Mice

Dual Adeno-Associated Virus Vector mediated gene therapy for autosomal recessive Stargardt Disease

Successful rescue of M-cone function in aged M-opsin knock-out mice, a model for blue cone monochromacy

Long-term preservation of photoreceptor function and structure following early-stage treatment by AAV-mediated gene augmentation in canine model of NPHP5 Leber congenital amaurosis

Neuroprotection by overexpression of transcription factor Max in experimental glaucoma.

Interocular symmetry of foveal cone topography in achromatopsia (ACHM)

Very long chain ceramides production mediated by ELOVL4 stabilizes tight junctions and prevents diabetes-induced retinal vascular permeability

Phenotypic consequences of amino acid substitutions at the S163 position in C1QTNF5 protein following expression in murine RPE

The expression pattern and pathological effects of CLRN1 mutant proteins in the mouse retina

Assessment of cone outer segment defects and rescue in the Opn1mw/sw double knockout mouse

BEST1 gene augmentation therapy corrects light-modulated retinal micro-detachments

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