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ARVO Annual Meeting Abstract June 2023

Gene therapy restores vision to the all-cone Nrl -/- /Opn1mw -/- /Opn1sw -/- mouse model of blue cone monochromacy

Marion Cahill; Kathryn Chmelik; Emily R. Sechrest; Robert J. Barbera; Wolfgang Baehr; Wen-Tao Deng

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):769.

ARVO Annual Meeting Abstract June 2022

The cytoskeletal network and cellular function in rod and cone photoreceptors are disrupted in the absence of NUDC expression

Alecia K Gross; Mary Anne Garner; Evan Boitet; Anushree Gade; Nicholas J. Reish; Guoxin Ying; Wolfgang Baehr; Meredith Hubbard

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1927 – A0073.

ARVO Annual Meeting Abstract June 2022

Dynein Dysregulation Due to the Absence of NUDC leads to Mitochondrial Mislocalization and Dysfunction in Rod Photoreceptors

Hailey Jori Levi; Meredith Hubbard; Mary Anne Garner; TJ Hollingsworth; Ke Jiang; Nat Nelson; Anushree Gade; Drue Benefield; Guoxin Ying; Wolfgang Baehr; Bryan W. Jones; Anand Swaroop; Glenn Rowe; Alecia K Gross

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3878 – A0080.

Biochemistry and Molecular Biology November 2021

Conditional Deletion of Cytoplasmic Dynein Heavy Chain in Postnatal Photoreceptors

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Tiffanie M. Dahl; Michelle Reed; Cecilia D. Gerstner; Wolfgang Baehr
TAGS: cytoplasm, dynein atpase, electroretinography, mice, photoreceptors, retina, rod photoreceptors, tamoxifen, tissue degeneration, proteins
Invest. Ophthalmol. Vis. Sci.. 2021; 62(14):23. https://doi.org/10.1167/iovs.62.14.23

ARVO Annual Meeting Abstract June 2021

The cytoskeletal network in photoreceptors is dependent upon NUDC expression

Alecia K Gross; Evan R Boitet; Anushree Gade; Nicholas J Reish; Drue Benefield; Guoxin Yang; Wolfgang Baehr; Glenn C. Rowe; Meredith G. Hubbard

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2597.

ARVO Annual Meeting Abstract June 2021

Disease mechanisms of X-linked cone dystrophy caused by missense mutations in the red and green cone opsins

Wen-Tao Deng; Ping Zhu; Frank M Dyka; Wolfgang Baehr; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1554.

ARVO Annual Meeting Abstract June 2020

NUDC is critical for regulation of photoreceptor cytoskeletal network

Alecia K Gross; Evan R Boitet; Nicholas J Reish; Drue Benefield; Guoxin Ying; Wolfgang Baehr; Glenn C Rowe; Meredith Hubbard

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1121.

ARVO Annual Meeting Abstract June 2020

Rescue of cone structure and function in Opn1mw/sw double knockout mice

Wen-Tao Deng; Ping Zhu; Tiffanie Dahl; Wolfgang Baehr; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2456.

ARVO Annual Meeting Abstract June 2020

Retina- and rod-specific knockout of centrosomal protein CEP164

Michelle Reed; Ken-ichi Takemaru; Wolfgang Baehr

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3779.

ARVO Annual Meeting Abstract June 2020

Conditional Dync1h1 embryonic deletion and tamoxifen induced knockout in the adult mouse

Tiffanie Dahl; Michelle Reed; Cecilia Gerstner; Wolfgang Baehr

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3789.

Retina August 2019

Rescue of M-cone Function in Aged Opn1mw −/− Mice, a Model for Late-Stage Blue Cone Monochromacy

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Wen-Tao Deng; Jie Li; Ping Zhu; Beau Freedman; W. Clay Smith; Wolfgang Baehr; William W. Hauswirth
TAGS: gene therapy, mice, retinal cone, opsin
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3644-3651. https://doi.org/10.1167/iovs.19-27079

ARVO Annual Meeting Abstract July 2019

Successful rescue of M-cone function in aged M-opsin knock-out mice, a model for blue cone monochromacy

Wen-Tao Deng; Jie Li; Ping Zhu; Wolfgang Baehr; William Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3419.

ARVO Annual Meeting Abstract July 2019

Germline deletion of both CETN2 and CETN3 destabilizes the distal connecting cilium of mouse photoreceptors

Guoxin Ying; Jeanne M. Frederick; Wolfgang Baehr

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3977.

ARVO Annual Meeting Abstract July 2019

NudC is critical for outer segment disk size and photoreceptor cell viability

Meredith G. Hubbard; Evan R Boitet; Laurence M Black; Nicholas J Reish; Guoxin Ying; Wolfgang Baehr; Subhashini Bolisetty; Alecia K Gross

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3985.

ARVO Annual Meeting Abstract July 2018

Mouse cones expressing only S-opsin exhibit rod-like saturation

Gabriel Peinado; Kaitryn Ronning; Wolfgang Baehr; Marie E. Burns; Edward N. Pugh

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1978.

ARVO Annual Meeting Abstract July 2018

PDE6D dependent G olf subunit trafficking in olfactory epithelium

Michelle Reed; Guoxin Ying; Wolfgang Baehr

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2358.

ARVO Annual Meeting Abstract July 2018

Assessment of cone outer segment defects and rescue in the Opn1mw/sw double knockout mouse

Tiffanie M. Dahl; Michelle Reed; Cecilia D. Gerstner; Guoxin Ying; Wentao Deng; William W Hauswirth; Wolfgang Baehr

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3054.

ARVO Annual Meeting Abstract July 2018

Understanding the molecular mechanisms underlying retina degeneration in INPP5E-Joubert Syndrome

Ali Sakawa Sharif; Christin Hanke-Gogokhia; Jeanne M Frederick; Wolfgang Baehr

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3068.

ARVO Annual Meeting Abstract July 2018

cGMP/PKG Signaling Regulation of Endoplasmic Reticulum Calcium Channels in Cyclic Nucleotide-gated Channel-deficient Cones

Fan Yang; Hongwei Ma; Michael Butler; Wolfgang Baehr; Martin Biel; Stylianos Michalakis; Xi-Qin Ding

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4966.

ARVO Annual Meeting Abstract June 2017

ARL3-GTP and its GEF ARL13b regulate photoreceptor transition zone formation

Wolfgang Baehr; Christin Hanke-Gogokhia; Houbin Zhang; Jeanne M Frederick

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2056.

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Gene therapy restores vision to the all-cone Nrl -/- /Opn1mw -/- /Opn1sw -/- mouse model of blue cone monochromacy

The cytoskeletal network and cellular function in rod and cone photoreceptors are disrupted in the absence of NUDC expression

Dynein Dysregulation Due to the Absence of NUDC leads to Mitochondrial Mislocalization and Dysfunction in Rod Photoreceptors

Conditional Deletion of Cytoplasmic Dynein Heavy Chain in Postnatal Photoreceptors

The cytoskeletal network in photoreceptors is dependent upon NUDC expression

Disease mechanisms of X-linked cone dystrophy caused by missense mutations in the red and green cone opsins

NUDC is critical for regulation of photoreceptor cytoskeletal network

Rescue of cone structure and function in Opn1mw/sw double knockout mice

Retina- and rod-specific knockout of centrosomal protein CEP164

Conditional Dync1h1 embryonic deletion and tamoxifen induced knockout in the adult mouse

Rescue of M-cone Function in Aged Opn1mw −/− Mice, a Model for Late-Stage Blue Cone Monochromacy

Successful rescue of M-cone function in aged M-opsin knock-out mice, a model for blue cone monochromacy

Germline deletion of both CETN2 and CETN3 destabilizes the distal connecting cilium of mouse photoreceptors

NudC is critical for outer segment disk size and photoreceptor cell viability

Mouse cones expressing only S-opsin exhibit rod-like saturation

PDE6D dependent G olf subunit trafficking in olfactory epithelium

Assessment of cone outer segment defects and rescue in the Opn1mw/sw double knockout mouse

Understanding the molecular mechanisms underlying retina degeneration in INPP5E-Joubert Syndrome

cGMP/PKG Signaling Regulation of Endoplasmic Reticulum Calcium Channels in Cyclic Nucleotide-gated Channel-deficient Cones

ARL3-GTP and its GEF ARL13b regulate photoreceptor transition zone formation

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