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Refractive Intervention May 2025

Association Between Inflammatory Cytokines and Refractive Errors: A Bidirectional Mendelian Randomization Study

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Yue Xu; Xing-Xuan Dong; Yun Wang; Xin-Yu Zhuang; Ying-Jie Chen; Xiao-Feng Zhang; Chen-Wei Pan
TAGS: cytokine, mendelian randomization analysis, refractive errors, ciliary motility disorders
Trans. Vis. Sci. Tech.. 2025; 14(5):1. https://doi.org/10.1167/tvst.14.5.1

Includes: Supplemental Content

Cornea April 2025

Pax6 Directly Regulates the Raver2/sFlt-1 Expression in Corneal Epithelial Cells to Maintain the Cornea's Avascular Privilege

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Haiqi Xiao; Li Hu; Xiongshi Lin; Linchang Liu; Xing Dong; Liting Yang; Ying Liu; Zhichong Wang; Ying Tian; Shuangyong Wang
TAGS: pax6 transcription factor, soluble fms-like tyrosine kinase 1
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):52. https://doi.org/10.1167/iovs.66.4.52

Includes: Supplemental Content

Retinal Cell Biology November 2024

Single-Cell Multiomics Profiling Reveals Heterogeneity of Müller Cells in the Oxygen-Induced Retinopathy Model

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Xueming Yao; Ziqi Li; Yi Lei; Qiangyun Liu; Siyue Chen; Haokun Zhang; Xue Dong; Kai He; Ju Guo; Mulin Jun Li; Xiaohong Wang; Hua Yan
TAGS: astrocytes, genes, heterogeneity, mice, multiomics, oxygen, retinal diseases, small nuclear rna, cell communication, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):8. https://doi.org/10.1167/iovs.65.13.8

Includes: Supplemental Content

Cornea & External Disease September 2024

Drug-Related Keratitis: A Real-World FDA Adverse Event Reporting System Database Study

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Shi-Nan Wu; Xiao-Dong Chen; Qing-He Zhang; Yu-Qian Wang; Dan Yan; Chang-Sheng Xu; Shao-Pan Wang; Linfangzi Zhu; Dan-Yi Qin; Shu-Jia Guo; Lin Chen; Yu-Wen Liu; Caihong Huang; Jiaoyue Hu; Zuguo Liu
TAGS: keratitis, united states food and drug administration, incident reporting
Trans. Vis. Sci. Tech.. 2024; 13(9):17. https://doi.org/10.1167/tvst.13.9.17

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Smoking aggravates neovascular age-related macular degeneration via Sema4D-PlexinB1 axis-mediated activation of pericytes

Kai He; Xue Dong; Tianjing Yang; Ziqi Li; Xiaohong Wang; Hua Yan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4996.

ARVO Annual Meeting Abstract June 2024

Hotspots and trends of stem cell therapy in ocular diseases from 2013 to 2023: a bibliometric analysis

Xuran Dong; Sitong Pan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4182.

ARVO Annual Meeting Abstract June 2024

GLP-1RA eye drops suppress lacrimal gland inflammation in a murine model of type 1 diabetes

Yan Sun; Yue Zhang; Fan Shi; Congyao Wang; Xia Dong; Pengxia Wan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6530.

ARVO Annual Meeting Abstract June 2024

Delivering Integrated Eye Care through Social Franchising Model: An Implementation Science Study in Rural China

Jie Hao; Xiaodong Dong; Jing Fu; Xiaochen Ma

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6392.

ARVO Annual Meeting Abstract June 2024

World's First CRISPR/RNA-Targeting Therapy (HG202) for Patients with Neovascular Age-Related Macular Degeneration

Alvin Luk; Dongjun Xing; Boshi Liu; Weiwei Liu; Shuaishuai Zhang; Yuhan Jiang; Xuan Yao; Linyu Shi; Hui Yang; Yiqun Yuan; Xiaorong Li

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4357.

Immunology and Microbiology June 2024

A Novel Murine Model for Lupus-Like Ocular Chronic Graft-Versus-Host Disease

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Yan Sun; Yue Zhang; Jiani Shen; Fan Shi; Ye Li; Congyao Wang; Xia Dong; Tingting Chen; Fenfen Yu; Yi Zhou; Pengxia Wan
TAGS: discoid lupus erythematosus, graft-versus-host disease, chronic, lupus erythematosus, mice, systemic lupus erythematosus, cornea
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):20. https://doi.org/10.1167/iovs.65.6.20

Includes: Supplemental Content

Cornea & External Disease October 2023

Establishing a Mouse Model of Chlorpromazine-Induced Corneal Trigeminal Denervation

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Xiongshi Lin; Peipei Xu; Ying Tian; Haiqi Xiao; Xing Dong; Shuangyong Wang
TAGS: chlorpromazine, cornea, denervation, mice
Trans. Vis. Sci. Tech.. 2023; 12(10):21. https://doi.org/10.1167/tvst.12.10.21

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Natural killer cells cooperate with neutrophils to suppress pathological angiogenesis in neovascular age-related macular degeneration

Xue Dong; Yinting Song; Xiaohong Wang; Hua Yan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3908.

ARVO Annual Meeting Abstract June 2023

Effects of AMPK activator and inhibitor on penetrating Transplantation

Chen Ouyang; Lijie Xie; Chao Hou; Jing Wu; Xiaojuan Dong; Ting Huang

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4797.

Genetics February 2023

De Novo Mutations Contributes Approximately 7% of Pathogenicity in Inherited Eye Diseases

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Wei Li; Xiang-Dong He; Zheng-Tao Yang; Dong-Ming Han; Yan Sun; Yan-Xian Chen; Xiao-Tong Han; Si-Cheng Guo; Yu-Ting Ma; Xin Jin; Huan-Ming Yang; Ya Gao; Zhuo-Shi Wang; Jian-Kang Li; Wei He
TAGS: de novo mutation, epileptiform discharges, eye diseases, genes, improvised explosive devices, pathogenicity, proband, marfan syndrome, ectopia lentis, parent
Invest. Ophthalmol. Vis. Sci.. 2023; 64(2):5. https://doi.org/10.1167/iovs.64.2.5

Includes: Supplemental Content

Cornea June 2022

Lysozyme Protects Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Inflammation in Human Corneal Epithelial Cells

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Yinting Song; Haokun Zhang; Yanfang Zhu; Xiao Zhao; Yi Lei; Wei Zhou; Jinguo Yu; Xue Dong; Xiaohong Wang; Mei Du; Hua Yan
TAGS: covid-19, infections, inflammation, muramidase, proteins, severe acute respiratory syndrome, corneal epithelial cells, sars-cov-2, coronavirus
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):16. https://doi.org/10.1167/iovs.63.6.16

Retina May 2022

Identification of TPBG-Expressing Amacrine Cells in DAT-tdTomato Mouse

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Wanjing Huang; Qiang Xu; Feng Liu; Jing Su; Dongchang Xiao; Lei Tang; Zhao-Zhe Hao; Ruifeng Liu; Kangjian Xiang; Yalan Bi; Zhichao Miao; Xialin Liu; Yizhi Liu; Sheng Liu
TAGS: abdominal compartment syndrome, acute coronary syndromes, american cancer society, american college of surgeons, mice, retina, immunohistochemistry, amacrine cells
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):13. https://doi.org/10.1167/iovs.63.5.13

Includes: Supplemental Content

Retina September 2021

Vitreous M2 Macrophage-Derived Microparticles Promote RPE Cell Proliferation and Migration in Traumatic Proliferative Vitreoretinopathy

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Yinting Song; Mengyu Liao; Xiao Zhao; Han Han; Xue Dong; Xiaohong Wang; Mei Du; Hua Yan
TAGS: macrophages, massively-parallel genome sequencing, mucopolysaccharidoses, retinal pigment cell, vitreous body, cell-derived microparticles, vitreoretinopathy, proliferative
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):26. https://doi.org/10.1167/iovs.62.12.26

Includes: Supplemental Content

Retina July 2021

Activated Blood Coagulation Factor X (FXa) Contributes to the Development of Traumatic PVR Through Promoting RPE Epithelial-Mesenchymal Transition

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Han Han; Xiao Zhao; Mengyu Liao; Yinting Song; Caiyun You; Xue Dong; Xueli Yang; Xiaohong Wang; Bo Huang; Mei Du; Hua Yan
TAGS: epithelial to mesenchymal transition, eye, factor x, fibrosis, mice, ocular trauma, oryctolagus cuniculus, receptor, par-1, retinal pigment cell, vitreous body
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):29. https://doi.org/10.1167/iovs.62.9.29

Includes: Supplemental Content

Clinical and Epidemiologic Research July 2020

Retinal Neurovascular Impairment in Patients with Essential Hypertension: An Optical Coherence Tomography Angiography Study

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Qingsheng Peng; Yijun Hu; Manqing Huang; Ying Wu; Pingting Zhong; Xinran Dong; Qiaowei Wu; Baoyi Liu; Cong Li; Jinxian Xie; Yu Kuang; Danqing Yu; Honghua Yu; Xiaohong Yang
TAGS: angiogram, hypertension, hypertension, essential, optical coherence tomography, peripheral neurovascular compromise, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):42. https://doi.org/10.1167/iovs.61.8.42

Visual Neuroscience December 2019

CoPP-Induced-Induced HO-1 Overexpression Alleviates Photoreceptor Degeneration With Rapid Dynamics: A Therapeutic Molecular Against Retinopathy

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Ye Tao; Lun Cai; Dawei Zhou; Chunhui Wang; Zhao Ma; Xiaofei Dong; Guanghua Peng
TAGS: cyclophosphamide/prednisone/procarbazine/vincristine, photoreceptors, retina, tissue degeneration, retinal diseases, mice, protein overexpression, therapeutics
Invest. Ophthalmol. Vis. Sci.. 2019; 60(15):5080-5094. https://doi.org/10.1167/iovs.19-26876

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Association Between Inflammatory Cytokines and Refractive Errors: A Bidirectional Mendelian Randomization Study

Pax6 Directly Regulates the Raver2/sFlt-1 Expression in Corneal Epithelial Cells to Maintain the Cornea's Avascular Privilege

Single-Cell Multiomics Profiling Reveals Heterogeneity of Müller Cells in the Oxygen-Induced Retinopathy Model

Drug-Related Keratitis: A Real-World FDA Adverse Event Reporting System Database Study

Smoking aggravates neovascular age-related macular degeneration via Sema4D-PlexinB1 axis-mediated activation of pericytes

Hotspots and trends of stem cell therapy in ocular diseases from 2013 to 2023: a bibliometric analysis

GLP-1RA eye drops suppress lacrimal gland inflammation in a murine model of type 1 diabetes

Delivering Integrated Eye Care through Social Franchising Model: An Implementation Science Study in Rural China

World's First CRISPR/RNA-Targeting Therapy (HG202) for Patients with Neovascular Age-Related Macular Degeneration

A Novel Murine Model for Lupus-Like Ocular Chronic Graft-Versus-Host Disease

Establishing a Mouse Model of Chlorpromazine-Induced Corneal Trigeminal Denervation

Natural killer cells cooperate with neutrophils to suppress pathological angiogenesis in neovascular age-related macular degeneration

Effects of AMPK activator and inhibitor on penetrating Transplantation

De Novo Mutations Contributes Approximately 7% of Pathogenicity in Inherited Eye Diseases

Lysozyme Protects Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Inflammation in Human Corneal Epithelial Cells

Identification of TPBG-Expressing Amacrine Cells in DAT-tdTomato Mouse

Vitreous M2 Macrophage-Derived Microparticles Promote RPE Cell Proliferation and Migration in Traumatic Proliferative Vitreoretinopathy

Activated Blood Coagulation Factor X (FXa) Contributes to the Development of Traumatic PVR Through Promoting RPE Epithelial-Mesenchymal Transition

Retinal Neurovascular Impairment in Patients with Essential Hypertension: An Optical Coherence Tomography Angiography Study

CoPP-Induced-Induced HO-1 Overexpression Alleviates Photoreceptor Degeneration With Rapid Dynamics: A Therapeutic Molecular Against Retinopathy

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