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Anatomy and Pathology/Oncology April 2025

Novel OCT Angiography Features, von Hippel–Lindau Disease Association, and Genetic Characterization of Juxtapapillary Retinal Capillary Hemangiomas

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Xiaonan Zhuang; Fengjuan Gao; Yi Xuan; Zhongcui Sun; Xiaofeng Ye; Xin Huang; Rui Jiang; Jihong Wu; Min Wang; Qing Chang; Gezhi Xu; Wei Liu
TAGS: angiogram, atypical, eye, genetics, retinal capillary hemangioma, von hippel-lindau syndrome, follow-up
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):34. https://doi.org/10.1167/iovs.66.4.34

Includes: Supplemental Content

Cornea February 2025

Melatonin Alleviates Age-Related Lacrimal Gland Dysfunction Via SIRT-1/NLRP3 Pathway

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Chao Wang; Yu-Zhi Li; Huan Guo; Shi-Rui Zhou; Xi Peng; Jia-Song Wang; Hua-Tao Xie; Ming-Chang Zhang
TAGS: lacrimal gland, nlr family, pyrin domain-containing 3 protein, sirt1 gene, melatonin, pathophysiology, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):51. https://doi.org/10.1167/iovs.66.2.51

Includes: Supplemental Content

Cornea February 2025

Stiffness Regulates the Morphology and Stemness of Limbal Niche Cells Through Unique nYAP/cYAP Translocation

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Xiao Zhou; Lingjuan Xu; Yongyao Tan; Wei Wang; Xiaoyu Huang; Guigang Li
TAGS: language morphology, morphology, phenotype, translocation (genetics), diffuse idiopathic skeletal hyperostosis, cornea, stem cells, proteins, western blotting, patient isolation
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):43. https://doi.org/10.1167/iovs.66.2.43

Includes: Supplemental Content

Retina January 2025

Perfusion Capacity as a Predictive Index for Assessing Visual Functional Recovery in Patients With Idiopathic Epiretinal Membrane

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Jinlian Zhan; Chen Chen; Tong Wang; Qi Zhang; Xia Huang; Lin Lu; Xiujuan Zhao
TAGS: epiretinal membrane, perfusion, postoperative care, preoperative care, recovery of function, retinal vasculature, vision, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2025; 14(1):19. https://doi.org/10.1167/tvst.14.1.19

Includes: Supplemental Content

Cornea January 2025

Caspase 3/GSDME-Mediated Corneal Epithelial Pyroptosis Promotes Dry Eye Disease

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Ling Wang; Ye Tian; Hui Zhang; Yongxiao Dong; Xia Hua; Xiaoyong Yuan
TAGS: caspase-3, cornea, dry eye syndromes, epithelium, mice, proteins, pyroptosis, apoptosis, genes, western blotting
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):24. https://doi.org/10.1167/iovs.66.1.24

Includes: Supplemental Content

Retina November 2024

Midperipheral Microvascular Defects and Their Associations With Vitreoretinal Abnormalities in Early-Stage Familial Exudative Vitreoretinopathy

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Juan Zhang; Lu Ruan; Chen Jiang; Qian Yang; Qing Chang; Xin Huang
TAGS: familial exudative vitreoretinopathies
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):4. https://doi.org/10.1167/iovs.65.13.4

Includes: Supplemental Content

Retinal Cell Biology October 2024

Retinal Organoid Microenvironment Enhanced Bioactivities of Microglia-Like Cells Derived From HiPSCs

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Mei-Ling Gao; Tong-Yu Wang; Xin Lin; Chun Tang; Mengyao Li; Zhan-Pei Bai; Zhi-Cong Liu; Li-Jun Chen; Qing-Ran Kong; Shao-Hui Pan; Shan-Shan Zeng; Ya Guo; Jian-Qi Cai; Xiu-Feng Huang; Jun Zhang
TAGS: foreign medical graduates, microglia, organoids, coculture techniques
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):19. https://doi.org/10.1167/iovs.65.12.19

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

TRPV1-Targeted Hydrogel against Pyroptosis of Dry Eye Disease In Vitro and In Vivo

Xiangyu Ding; Xia Hua

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5745.

ARVO Annual Meeting Abstract June 2024

Caspase-1-Dependent Pyroptosis of Human Corneal Epithelial Cells Promotes RIP3/MLKL Mediated Necroptosis in the Pathogenesis of Dry Eye

Xia Hua; Xiangyu Ding; Jingqing Mu; Baoyue Mi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5744.

ARVO Annual Meeting Abstract June 2024

Reactive Oxygen Species-Responsive detachable Microneedle Patches for Intelligent Dry Eye Syndrome Management

Jingqing Mu; Xiangyu Ding; Yapeng Song; Baoyue Mi; Xia Hua

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5747.

ARVO Annual Meeting Abstract June 2024

Integration of vitreous metabolomics and lipidomics for vitreous-retina adhension in proliferative diabetic retinopathy

Ying Cui; Zhongning Huang; Lei Xi; Anyi Liang; Liang Zhang; Mingsi Chi; Tai Guo; Yue Liu; Xiaofeng Huang; Yuman Li; Zhixin Mo

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):OD66.

ARVO Annual Meeting Abstract June 2024

Characteristics of Vitreoretinal Lymphoma in B-scan Ultrasonography

Junxiang Gu; Qian Chen; Peijun Zhang; Ting Zhang; Tingting Jiang; Min Zhou; Xin Huang; Gezhi Xu; Qing Chang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):807.

ARVO Annual Meeting Abstract June 2024

Diagnosing Glaucoma Based on a Large Language Model Chatbot

Hina Raja; Xiaoqin Huang; Mohammad Delsoz; Yeganeh Madadi; Asma Poursoroush; Asim Munawar; Malik Kahook; Siamak Yousefi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1636.

ARVO Annual Meeting Abstract June 2024

Discovering novel glaucoma neural repair genes using computational approaches based on single-cell RNA-seq data

Yeganeh Madadi; Lu Lu; Hao Chen; Xiaoqin Huang; Hina Raja; Mohammad Delsoz; Robert W. Williams; Monica M Jablonski; Siamak Yousefi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):640.

ARVO Annual Meeting Abstract June 2024

Predicting glaucoma before onset using a large language model chatbot

Siamak Yousefi; Xiaoqin Huang; Hina Raja; Yeganeh Madadi; Mohammad Delsoz; Asma Poursoroush; Malik Kahook

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1643.

ARVO Annual Meeting Abstract June 2024

Forecasting glaucoma from multimodal data using deep learning models

Xiaoqin Huang; Asma Poursoroush; Yeganeh Madadi; Hina Raja; Mohammad Delsoz; Louis R. Pasquale; Michael V. Boland; Chris A Johnson; Nazlee Zebardast; Siamak Yousefi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):374.

ARVO Annual Meeting Abstract June 2024

Identification of a suptype of ocular hypertensive eyes with the best response to medications

Asma Poursoroush; Vida Abedi; Xiaoqin Huang; Mohammad Delsoz; Siamak Yousefi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1639.

ARVO Annual Meeting Abstract June 2024

Association between glaucoma and mental health disorders by race and ethnicity based on a large national database

Mohammad Delsoz; Hina Raja; Zain S Hussain; Vahid Mohammadzadeh; Yeganeh Madadi; Xiaoqin Huang; Asma Poursoroush; Jesse Wesberry; Brian Jerkins; Claire Wright; Elliott Kanner; Siamak Yousefi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2441.

ARVO Annual Meeting Abstract June 2024

Choroidal vascularity index (CVI) changes associated with lesion activity of polypoidal choroidal vasculopathy (PCV)

Qiyu Bo; Xiaoxu Huang; Jieqiong Chen; Fenghua Wang; Xiaodong Sun

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2304.

ARVO Annual Meeting Abstract June 2024

Optical biometry study of the human foveal isoplanatic patch

Xiaojing Huang; Aubrey Hargrave; Julie Bentley; Alfredo Dubra

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3378.

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Novel OCT Angiography Features, von Hippel–Lindau Disease Association, and Genetic Characterization of Juxtapapillary Retinal Capillary Hemangiomas

Melatonin Alleviates Age-Related Lacrimal Gland Dysfunction Via SIRT-1/NLRP3 Pathway

Stiffness Regulates the Morphology and Stemness of Limbal Niche Cells Through Unique nYAP/cYAP Translocation

Perfusion Capacity as a Predictive Index for Assessing Visual Functional Recovery in Patients With Idiopathic Epiretinal Membrane

Caspase 3/GSDME-Mediated Corneal Epithelial Pyroptosis Promotes Dry Eye Disease

Midperipheral Microvascular Defects and Their Associations With Vitreoretinal Abnormalities in Early-Stage Familial Exudative Vitreoretinopathy

Retinal Organoid Microenvironment Enhanced Bioactivities of Microglia-Like Cells Derived From HiPSCs

TRPV1-Targeted Hydrogel against Pyroptosis of Dry Eye Disease In Vitro and In Vivo

Caspase-1-Dependent Pyroptosis of Human Corneal Epithelial Cells Promotes RIP3/MLKL Mediated Necroptosis in the Pathogenesis of Dry Eye

Reactive Oxygen Species-Responsive detachable Microneedle Patches for Intelligent Dry Eye Syndrome Management

Integration of vitreous metabolomics and lipidomics for vitreous-retina adhension in proliferative diabetic retinopathy

Characteristics of Vitreoretinal Lymphoma in B-scan Ultrasonography

Diagnosing Glaucoma Based on a Large Language Model Chatbot

Discovering novel glaucoma neural repair genes using computational approaches based on single-cell RNA-seq data

Predicting glaucoma before onset using a large language model chatbot

Forecasting glaucoma from multimodal data using deep learning models

Identification of a suptype of ocular hypertensive eyes with the best response to medications

Association between glaucoma and mental health disorders by race and ethnicity based on a large national database

Choroidal vascularity index (CVI) changes associated with lesion activity of polypoidal choroidal vasculopathy (PCV)

Optical biometry study of the human foveal isoplanatic patch

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