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Cornea July 2025

DJ-1 Promotes Diabetic Corneal Epithelial Wound Healing by Attenuating Hyperglycemia-Induced Oxidative Stress Through Inhibiting PTEN

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Haoyu Li; Hanhan Peng; Benteng Ma; Xinyue Sun; Liwei Zhang; Baihua Chen
TAGS: cornea, diabetes mellitus, epithelium, hyperglycemia, oxidative stress, proteins, pten gene, wound healing, antioxidants, mitochondria
Invest. Ophthalmol. Vis. Sci.. 2025; 66(9):20. https://doi.org/10.1167/iovs.66.9.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2025

A normative cone photoreceptor database study using Adaptive Optics Scanning Light Ophthalmoscopy: insights from the Chinese population.

Weixiao Fan; Ji Ren; Yuan Zong; Jiaojiao Wei; Jiajie Zhao; Yuanyuan Liu; Xiaohan Wu; Haochen Wang; Jianchong Li; Chuanzhen Zheng; Tao Cai; Xiying Mao; Na Su; Nianfeng Tang; Tianyu Mao; Jianfeng Luo; Songtao Yuan; Yong Zeng; Wei Zhou; Chunhui Jiang; Qinghuai Liu; Zhengzheng Wu; Hua Yan; Xinghuai Sun; Jie Zhang

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1009.

ARVO Annual Meeting Abstract June 2025

Pre-clinical Evaluation of Ectoine-Based Binary Combinations in Alleviating Dry Eye

xin Sun; Ruijin Zhao; Botao Wang; Ruiyan Wang; Tianmeng Zhang; Haining Shi

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1569.

ARVO Annual Meeting Abstract June 2025

Faricimab for Polypoidal Choroidal Vasculopathy: Week 16 Results From the Phase 3b/4 SALWEEN Trial

Junyeop Lee; Gemmy Cheung; Shih-Jen Chen; Tomohiro Iida; Adrian Hock Chaun Koh; Won Ki Lee; Paisan Ruamviboonsuk; Xiaodong Sun; Yasuo Yanagi; Ruobing Bai; Philippe Margaron; Anh Nguyen Duc; Timothy Y Y Lai

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1859.

ARVO Annual Meeting Abstract June 2025

Intravitreal High-dose Efdamrofusp Alfa (IBI302) in Patients with Neovascular Age-related Macular Degeneration: A Randomized, Double-masked, Active-controlled, Phase 2 Study

Xiaodong Sun; Qinghuai Liu; Yanping Song; Jianping Dong; wenbin wei; Weiqi Chen; Hong Dai; Wei Wang; Miaoqin Wu; Guohong Zhou; Jinglin Zhang; Xuan Xiao; Rongrong Zhu; Ying Wen; Jilong Hao; Chaopeng Li; Haoyu Li; Li Li; Yafang Wang; Xiaoyu Chen; Shujie Lu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):443.

ARVO Annual Meeting Abstract June 2025

Enhancing Ophthalmic Admission Reports with Multi-Agent Large Language Models

Yupeng Xu; Junxiang Fan; Maolin Wang; Jie Feng; Xiaodong Sun

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4639.

ARVO Annual Meeting Abstract June 2025

Comprehensive Genotype-Phenotype Analysis of Rhodopsin Variants in a Chinese Cohort: Correlating Protein Functional Alterations with Disease Progression

Chenyue Hang; Tianyuan Zhao; Zhixuan Chen; Lin Chen; Ting Zhang; Xiaoling Wan; Jieqiong Chen; Xiaodong Sun

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):6051.

ARVO Annual Meeting Abstract June 2025

Association between grip strength and the risk of glaucoma: A population-based prospective cohort study

Guanran Zhang; Yanlin Qu; Huixun Jia; Xiaodong Sun

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1654.

ARVO Annual Meeting Abstract June 2025

Multi-Wavelength Photobiomodulation Mitigates Retinal Ganglion Cell Degeneration

Yuening Shen; Jianguo Sun; Xinghuai Sun

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):OD71.

ARVO Annual Meeting Abstract June 2025

tRNA U34 modification regulates endothelial cell fate and angiogenesis via coordinated protein synthesis and energy metabolism

Tianyuan Zhao; Bo Yu; Xiaodong Sun

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5554.

ARVO Annual Meeting Abstract June 2025

Foveal Sparing on SD-OCT: An Imaging Marker for Predicting Inherited Retinal Degeneration Progression

Zilin Wang; Tong Li; Shuoyang Wang; Lei Zhang; Junran Sun; Xiaodong Sun

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1435.

ARVO Annual Meeting Abstract June 2025

Development of a Novel Recombinant AAV Gene Therapy rAAV-AIPL1 for Leber’s Congenital Amaurosis 4 (LCA4) Disease

Tong Li; Zhuoyu NI; Fenghua Wang; Xiaodong Sun

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4273.

Cornea June 2025

Pyroptosis Mediated by ROS/Caspase-3/GSDME Pathway in Aspergillus fumigatus –Induced Fungal Keratitis

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Jingze Kan; Shiqi Song; Mengzhu Liu; Qiang Xu; Jieun Lee; Jintao Sun; Shasha Xue; Xiaoyan Sun; Chengye Che
TAGS: aspergillus fumigatus, caspase-3, cornea, fungal keratitis, infections, inflammation, keratitis, mice, pyroptosis, rna, small interfering
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):52. https://doi.org/10.1167/iovs.66.6.52

Cornea June 2025

HIF-1α Promotes Inflammatory Responses in Aspergillus Fumigatus Keratitis by Activating Pyroptosis Through Caspase-8/GSDMD Pathway

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Hua Yang; Mengzhu Liu; Shiqi Song; Qiang Xu; Jieun Lee; Jintao Sun; Shasha Xue; Xiaoyan Sun; Chengye Che
TAGS: aspergillus fumigatus, caspase-8, cornea, inflammatory response, keratitis, macrophages, mice, pyroptosis, infections, proteins
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):32. https://doi.org/10.1167/iovs.66.6.32

Retina September 2024

Preoperative OCT-Derived Nasal Perifoveal Retinal Nerve Fiber Layer Thickness Predictively Correlates Long-Term Visual Acuity Post Oil Removal Surgery

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Shuoyang Wang; Zilin Wang; Huixun Jia; Hong Wang; Tong Li; Junran Sun; Xiaodong Sun
TAGS: nose, preoperative care, retinal nerve fiber layer, silicone oils, surgical procedures, operative, visual acuity, risk factors
Trans. Vis. Sci. Tech.. 2024; 13(9):16. https://doi.org/10.1167/tvst.13.9.16

Includes: Supplemental Content

Artificial Intelligence July 2024

Deep Learning-Based Vascular Aging Prediction From Retinal Fundus Images

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Ruohong Wang; Yuhe Tan; Zheng Zhong; Suyun Rao; Ziqing Zhou; Lisha Zhang; Cuntai Zhang; Wei Chen; Lei Ruan; Xufang Sun

Trans. Vis. Sci. Tech.. 2024; 13(7):10. https://doi.org/10.1167/tvst.13.7.10

ARVO Annual Meeting Abstract June 2024

CRISPR-Cas9 correction of the PRPF6 c.2699G>A variant in retinitis pigmentosa patient-derived iPSCs rescues photoreceptor loss in retinal organoids

Yuqin Liang; Xihao Sun; Duan Chunwen; Zekai Cui; Shengru Mao; Shibo Tang; Jiansu Chen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3823.

ARVO Annual Meeting Abstract June 2024

Aberrant RP patient hiPSCs-derived RPE cells and base editing for repair

Xihao Sun; Yuqin Liang; Duan Chunwen; Shengru Mao; Jiansu Chen; Shibo Tang; Zekai Cui

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1577.

ARVO Annual Meeting Abstract June 2024

Retinal organoids with X-linked Retinoschisis RS1 (E72K) mutation exhibit photoreceptor developmental delay and are rescued by gene augmentation therapy

Duan Chunwen; Chengcheng Ding; Xihao Sun; Shengru Mao; Jiansu Chen; Shibo Tang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1547.

ARVO Annual Meeting Abstract June 2024

Gender differences in response to standardized unilateral optic nerve crush

Yuening Shen; Yadan Quan; Jianguo Sun; Xinghuai Sun

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6756.

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DJ-1 Promotes Diabetic Corneal Epithelial Wound Healing by Attenuating Hyperglycemia-Induced Oxidative Stress Through Inhibiting PTEN

A normative cone photoreceptor database study using Adaptive Optics Scanning Light Ophthalmoscopy: insights from the Chinese population.

Pre-clinical Evaluation of Ectoine-Based Binary Combinations in Alleviating Dry Eye

Faricimab for Polypoidal Choroidal Vasculopathy: Week 16 Results From the Phase 3b/4 SALWEEN Trial

Intravitreal High-dose Efdamrofusp Alfa (IBI302) in Patients with Neovascular Age-related Macular Degeneration: A Randomized, Double-masked, Active-controlled, Phase 2 Study

Enhancing Ophthalmic Admission Reports with Multi-Agent Large Language Models

Comprehensive Genotype-Phenotype Analysis of Rhodopsin Variants in a Chinese Cohort: Correlating Protein Functional Alterations with Disease Progression

Association between grip strength and the risk of glaucoma: A population-based prospective cohort study

Multi-Wavelength Photobiomodulation Mitigates Retinal Ganglion Cell Degeneration

tRNA U34 modification regulates endothelial cell fate and angiogenesis via coordinated protein synthesis and energy metabolism

Foveal Sparing on SD-OCT: An Imaging Marker for Predicting Inherited Retinal Degeneration Progression

Development of a Novel Recombinant AAV Gene Therapy rAAV-AIPL1 for Leber’s Congenital Amaurosis 4 (LCA4) Disease

Pyroptosis Mediated by ROS/Caspase-3/GSDME Pathway in Aspergillus fumigatus –Induced Fungal Keratitis

HIF-1α Promotes Inflammatory Responses in Aspergillus Fumigatus Keratitis by Activating Pyroptosis Through Caspase-8/GSDMD Pathway

Preoperative OCT-Derived Nasal Perifoveal Retinal Nerve Fiber Layer Thickness Predictively Correlates Long-Term Visual Acuity Post Oil Removal Surgery

Deep Learning-Based Vascular Aging Prediction From Retinal Fundus Images

CRISPR-Cas9 correction of the PRPF6 c.2699G>A variant in retinitis pigmentosa patient-derived iPSCs rescues photoreceptor loss in retinal organoids

Aberrant RP patient hiPSCs-derived RPE cells and base editing for repair

Retinal organoids with X-linked Retinoschisis RS1 (E72K) mutation exhibit photoreceptor developmental delay and are rescued by gene augmentation therapy

Gender differences in response to standardized unilateral optic nerve crush

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