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Articles June 2022

Two-Year Choroidal Thickness Attenuation and Its Associations in Healthy Chinese Adults

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Wenjia Cai; Xiao Guo; Wei Wang; Kun Xiong; Xiaotong Han; Xia Gong; Meng Yuan; Yuting Li; Xiaoling Liang; Yizhi Liu; Wenyong Huang
TAGS: adult, attenuation, chinese (other dialects), chinese people, eye, longitudinal studies
Trans. Vis. Sci. Tech.. 2022; 11(6):21. doi: https://doi.org/10.1167/tvst.11.6.21

Includes: Supplemental Content

Physiology and Pharmacology June 2022

Sleep Loss Causes Dysfunction in Murine Extraorbital Lacrimal Glands

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Shenzhen Huang; Hongli Si; Jiangman Liu; Di Qi; Xiaoting Pei; Dingli Lu; Sen Zou; Zhijie Li
TAGS: genes, mice, pathophysiology, rhythm, sleep deprivation, bodily secretions
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):19. doi: https://doi.org/10.1167/iovs.63.6.19

Includes: Supplemental Content

Retina June 2022

Characteristics of the Optic Nerve Head in Myopic Eyes Using Swept-Source Optical Coherence Tomography

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Dan Cheng; Kaiming Ruan; Minhui Wu; Yilin Qiao; Weiqian Gao; Hengli Lian; Meixiao Shen; Fangjun Bao; Yizeng Yang; Jun Zhu; Haiying Huang; Xianwei Meng; Lijun Shen; Yufeng Ye
TAGS: eye, myopia, optic disk, optical coherence tomography, microvascular network
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):20. doi: https://doi.org/10.1167/iovs.63.6.20

Cornea June 2022

Lysozyme Protects Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Inflammation in Human Corneal Epithelial Cells

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Yinting Song; Haokun Zhang; Yanfang Zhu; Xiao Zhao; Yi Lei; Wei Zhou; Jinguo Yu; Xue Dong; Xiaohong Wang; Mei Du; Hua Yan
TAGS: covid-19, infections, inflammation, muramidase, proteins, severe acute respiratory syndrome, corneal epithelial cells, sars-cov-2, coronavirus
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):16. doi: https://doi.org/10.1167/iovs.63.6.16

Retina June 2022

The Association of Fluid Volatility With Subretinal Hyperreflective Material and Ellipsoid Zone Integrity in Neovascular AMD

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Justis P. Ehlers; Nikhil Patel; Peter K. Kaiser; Jeffrey S. Heier; David M. Brown; Xiangyi Meng; Jamie Reese; Leina Lunasco; Thuy K. Le; Ming Hu; Sunil K. Srivastava
TAGS: exudative age-related macular degeneration, eye, personal integrity, volume, attenuation
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):17. doi: https://doi.org/10.1167/iovs.63.6.17

Includes: Supplemental Content

Articles June 2022

Correlation Between Laser Speckle Flowgraphy and OCT-Derived Retinal and Choroidal Metrics in Healthy Human Eye

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Yiming Lu; Hao Zhou; Xiao Zhou; Yuxuan Chen; Ruikang K. Wang
TAGS: cortical blindness, eye, lasers, retina, retinal vessels, correlation studies, maps, choroid
Trans. Vis. Sci. Tech.. 2022; 11(6):15. doi: https://doi.org/10.1167/tvst.11.6.15

Retina June 2022

A Novel Hypoxia-inducible Factor 1α Inhibitor KC7F2 Attenuates Oxygen-induced Retinal Neovascularization

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Xiaoyu Tang; Kaixuan Cui; Xi Lu; Peiqi Wu; Shanshan Yu; Boyu Yang; Yue Xu; Xiaoling Liang
TAGS: hypoxia, mice, oxygen, retina, retinal neovascularization, vascular endothelial growth factor a, western blotting, proteins, endothelial cells, attenuation
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):13. doi: https://doi.org/10.1167/iovs.63.6.13

Includes: Supplemental Content

Articles June 2022

Characteristics of Pupil Offset in Young Asian Adults With Mild-Moderate and High Myopia

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Shengshu Sun; Zhanglin Liu; Yuan Wu; Xiaowen Sun; Shaozhen Zhao; Yue Huang
TAGS: myopia, pupil, young adult, adult, asian
Trans. Vis. Sci. Tech.. 2022; 11(6):13. doi: https://doi.org/10.1167/tvst.11.6.13

Articles June 2022

Quantitative Assessment of Biomechanical Properties of the Human Keratoconus Cornea Using Acoustic Radiation Force Optical Coherence Elastography

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Yanzhi Zhao; Hongwei Yang; Yingjie Li; Yongbo Wang; Xiao Han; Yirui Zhu; Yubao Zhang; Guofu Huang
TAGS: cornea, elasticity imaging techniques, keratoconus, acoustics, optics, radiation, elasticity
Trans. Vis. Sci. Tech.. 2022; 11(6):4. doi: https://doi.org/10.1167/tvst.11.6.4

Genetics June 2022

Phenotype-Based Genetic Analysis Reveals Missing Heritability of ABCA4 -Related Retinopathy: Deep Intronic Variants and Copy Number Variations

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Lu Tian; Chunjie Chen; Yuning Song; Xiaohui Zhang; Ke Xu; Yue Xie; Zi-Bing Jin; Yang Li
TAGS: abca4 gene, alleles, copy number polymorphism, genetic analysis, introns, phenotype, retinal diseases
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):5. doi: https://doi.org/10.1167/iovs.63.6.5

Includes: Supplemental Content

Articles June 2022

Associations Among Outdoor Time, Skin Tanning, and the Risk of Surgically Treated Cataract for Australians 45 to 65 Years of Age

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Xiaotong Han; Jiaqing Zhang; Wei Wang; Zhenzhen Liu; Xuhua Tan; Xianwen Shang; Lei Zhang; Mingguang He; Lixia Luo
TAGS: cataract, cataract surgery, skin tanning, surgical procedures, operative, follow-up, sun exposure
Trans. Vis. Sci. Tech.. 2022; 11(6):3. doi: https://doi.org/10.1167/tvst.11.6.3

ARVO Annual Meeting Abstract June 2022

BDNF and cAMP promote retinal ganglion cell survival and function in a porcine model of traumatic optic neuropathy

Kathleen Heng; BaoXiang Li; Xin Xia; Rain Wen; Ashley Nies; Albert Y. Wu; Jeffrey L Goldberg

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):973 – F0370. doi:

ARVO Annual Meeting Abstract June 2022

Nuclear localized HDAC4 increases retinal ganglion cell survival after optic nerve crush injury

Ying Zhu; Jinliang Li; Minjuan Bian; Xin Xia; Michael Nahmou; Catalina Sun; Jeffrey L Goldberg; Michael Kapiloff

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):861. doi:

ARVO Annual Meeting Abstract June 2022

Aldose reductase inhibition promotes retinal ganglion cell survival after optic nerve injury

Mishal Rao; Yu-Kai Huang; Chandler Meadows; Chia-Chun Liu; Hui-Chun Cheng; Mengli Zhou; Yu-Chih Cheng; Xin Xia; Jeffrey L Goldberg; Takaaki Kuwajima; Kun-Che Chang

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1603 – A0426. doi:

ARVO Annual Meeting Abstract June 2022

Impact of Neurofibromatosis type 1 (NF1) heterozygosity on RGC death after optic nerve injury

Xin Xia; Catalina Sun; Ziming Luo; Saishravan Shyamsundar; Kristina Russano; Jeffrey L Goldberg

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):990 – F0387. doi:

Cornea June 2022

Corneal Epithelium–Derived Netrin-1 Alleviates Dry Eye Disease via Regulating Dendritic Cell Activation

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Chaoqun Yu; Peng Chen; Jing Xu; Susu Wei; Qilong Cao; Chuanlong Guo; Xianggen Wu; Guohu Di
TAGS: cornea, corneal epithelium, dendritic cells, dry eye syndromes, mice, netrin-1, regulation, antibodies
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):1. doi: https://doi.org/10.1167/iovs.63.6.1

ARVO Annual Meeting Abstract June 2022

From phenotype to genotype: glaucoma and psychiatric disorders

Xiayin Zhang; Xueli Zhang; Yu Huang; Xianwen Shang; Shunming Liu; Zhuoting Zhu; Xiaohong Yang; Mingguang He; Honghua Yu

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4016 – A0358. doi:

ARVO Annual Meeting Abstract June 2022

Intelligent Quantification of Retinal Ganglion Cells in the Entire Mouse Retina Based on Improved YOLOv5

Houbin Zhang; Jing Zhang; Yibo Huo; Jialiang Yang; Xiangzhou Wang; Boyun Yan; Xiaohui Du; Fang Yang; Juanxiu Liu; Lin Liu; Yong Liu

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2034 – A0475. doi:

ARVO Annual Meeting Abstract June 2022

Functional interaction between connexin 46 and periaxin in cataractogenesis

Xiaohua Gong; Vasantha Rao; Chun-hong Xia

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):19. doi:

ARVO Annual Meeting Abstract June 2022

Sumoylated Pax6 Regulates Lens Stalk Regression During Lens Development

David W Li; Jialing Fu; Fangyuan Liu; Shuyu Zheng; Yan Wang; Jingmiao Wang; yuan xiao; Jiawen Xiang; Yuwen Gan; Xingmiao Liang

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):836. doi:

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Two-Year Choroidal Thickness Attenuation and Its Associations in Healthy Chinese Adults

Sleep Loss Causes Dysfunction in Murine Extraorbital Lacrimal Glands

Characteristics of the Optic Nerve Head in Myopic Eyes Using Swept-Source Optical Coherence Tomography

Lysozyme Protects Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Inflammation in Human Corneal Epithelial Cells

The Association of Fluid Volatility With Subretinal Hyperreflective Material and Ellipsoid Zone Integrity in Neovascular AMD

Correlation Between Laser Speckle Flowgraphy and OCT-Derived Retinal and Choroidal Metrics in Healthy Human Eye

A Novel Hypoxia-inducible Factor 1α Inhibitor KC7F2 Attenuates Oxygen-induced Retinal Neovascularization

Characteristics of Pupil Offset in Young Asian Adults With Mild-Moderate and High Myopia

Quantitative Assessment of Biomechanical Properties of the Human Keratoconus Cornea Using Acoustic Radiation Force Optical Coherence Elastography

Phenotype-Based Genetic Analysis Reveals Missing Heritability of ABCA4 -Related Retinopathy: Deep Intronic Variants and Copy Number Variations

Associations Among Outdoor Time, Skin Tanning, and the Risk of Surgically Treated Cataract for Australians 45 to 65 Years of Age

BDNF and cAMP promote retinal ganglion cell survival and function in a porcine model of traumatic optic neuropathy

Nuclear localized HDAC4 increases retinal ganglion cell survival after optic nerve crush injury

Aldose reductase inhibition promotes retinal ganglion cell survival after optic nerve injury

Impact of Neurofibromatosis type 1 (NF1) heterozygosity on RGC death after optic nerve injury

Corneal Epithelium–Derived Netrin-1 Alleviates Dry Eye Disease via Regulating Dendritic Cell Activation

From phenotype to genotype: glaucoma and psychiatric disorders

Intelligent Quantification of Retinal Ganglion Cells in the Entire Mouse Retina Based on Improved YOLOv5

Functional interaction between connexin 46 and periaxin in cataractogenesis

Sumoylated Pax6 Regulates Lens Stalk Regression During Lens Development

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