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Genetics June 2022

Phenotype-Based Genetic Analysis Reveals Missing Heritability of ABCA4 -Related Retinopathy: Deep Intronic Variants and Copy Number Variations

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Lu Tian; Chunjie Chen; Yuning Song; Xiaohui Zhang; Ke Xu; Yue Xie; Zi-Bing Jin; Yang Li
TAGS: abca4 gene, alleles, copy number polymorphism, genetic analysis, introns, phenotype, retinal diseases
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):5. doi: https://doi.org/10.1167/iovs.63.6.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Gene knockdown of Col8a2 in mouse corneal endothelium by non-homologous end joint repair using adenovirus-mediated Crispr/Cas9

Hironori Uehara; Xiaohui Zhang; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1899 – A0045. doi:

ARVO Annual Meeting Abstract June 2022

Phenotype-Based Genetic Analysis Reveals Missing Heritability of ABCA4 -Related Retinopathy: Deep Intronic Variants and Copy Number Variations

tian lu; chunjie chen; yuning song; xiaohui zhang; ke xu; Yue Xie; Zi-Bing Jin; Yang Li

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2624. doi:

ARVO Annual Meeting Abstract June 2020

Subretinal Injection of AAVBR1 Targets the RPE and Outer Retina

Lara Carroll; Hironori Uehara; Xiaohui Zhang; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2901. doi:

Cornea January 2020

Topical Pergolide Enhance Corneal Nerve Regrowth Following Induced Corneal Abrasion

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Xiaohui Zhang; Santosh Muddana; Sangeetha Ravi Kumar; Joshua Nelson Burton; Pratima Labroo; Jill Shea; Parker Stocking; Cornelia Siegl; Bonnie Archer; Jayant Agarwal; Balamurali K. Ambati
TAGS: cornea, pergolide, corneal abrasions, neurons
Invest. Ophthalmol. Vis. Sci.. 2020; 61(1):4. doi: https://doi.org/10.1167/iovs.61.1.4

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Systemic Delivery Of Endothelial Colony Forming Cells Enables Vascular Integration Into Diabetic Mouse retinas, But Not Diabetic Mouse Retinas Treated With AAV2.COMP-Ang1

Lara Carroll; Xiaohui Zhang; Yufeng Huang; Yuanyuan Wu; Alan W Stitt; Tim M Curtis; Reinhold J. Medina; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2724. doi:

ARVO Annual Meeting Abstract July 2019

Gene therapy targeting PDGF-B for neovascular AMD

Xiaohui Zhang; Hironori Uehara; Lara Carroll; Bonnie Archer; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2981. doi:

ARVO Annual Meeting Abstract July 2019

TTR mutations and clinical characteristics of patients with vitreous amyloidosis

Xiaohui Zhang; Ke Xu; Xiaolin Xu; Yang Li

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):405. doi:

ARVO Annual Meeting Abstract July 2019

Mutation Screening of OPA1 in a cohort Chinese patients with Suspected Autosomal Dominant Optic Atrophy

YUE XIE; Ting Xiao; Ke Xu; Xiaohui Zhang; Yang Li

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):414. doi:

Retina June 2019

Intravitreal AAV2.COMP-Ang1 Attenuates Deep Capillary Plexus Expansion in the Aged Diabetic Mouse Retina

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Lara S. Carroll; Hironori Uehara; Daniel Fang; Susie Choi; Xiaohui Zhang; Malkit Singh; Zoya Sandhu; Philip M. Cummins; Tim M. Curtis; Alan W. Stitt; Bonnie J. Archer; Balamurali K. Ambati
TAGS: angiotensin i, blood capillaries, diabetes mellitus, mice, retina
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2494-2502. doi: https://doi.org/10.1167/iovs.18-26182

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Sector Retinitis Pigmentosa caused by mutations of the RHO gene

Yang Li; Ke Xu; Ting Xiao; Xiaohui Zhang; Yue Xie

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5422. doi:

ARVO Annual Meeting Abstract July 2018

Efficacy and Safety of AAV2.Flt23k Intraceptor Compared to AAV2.sFlt01

Xiaohui Zhang; Hironori Uehara; Lara S Carroll; Bonnie Archer; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1449. doi:

ARVO Annual Meeting Abstract July 2018

Comprehensive Molecular Screening in a Large Chinese Cohort with Usher Syndrome

Tengyang Sun; Ke Xu; Xiaohui Zhang; Yang Li

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2342. doi:

Genetics March 2018

Comprehensive Molecular Screening in Chinese Usher Syndrome Patients

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Tengyang Sun; Ke Xu; Yanfan Ren; Yue Xie; Xiaohui Zhang; Lu Tian; Yang Li
TAGS: chinese (other dialects), chinese people, genes, mutation, screening, usher syndrome, hearing loss, transanal endoscopic surgery, family, polymerase chain reaction
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1229-1237. doi: https://doi.org/10.1167/iovs.17-23312

Includes: Supplemental Content

Genetics July 2017

Screening of BEST1 Gene in a Chinese Cohort With Best Vitelliform Macular Dystrophy or Autosomal Recessive Bestrophinopathy

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Lu Tian; Tengyang Sun; Ke Xu; Xiaohui Zhang; Xiaoyan Peng; Yang Li
TAGS: autosomal recessive inheritance, chinese people, cohort studies, genes, mutation, screening, vitelliform dystrophy
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3366-3375. doi: https://doi.org/10.1167/iovs.17-21999

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Systemic Effects of AAV.COMPAng1 in the Ins2Akita Diabetic Mouse

Malkit Singh; Susie Choi; Petra Soininen; Zoya Sandhu; Daniel Fang; Deepti Vashist; Austin Bohner; Xiaohui Zhang; Yuanyuan Wu; Lara Carroll; Yufeng Huang; Hironori Uehara

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):190. doi:

Articles May 2017

Targeted Delivery of FLT-Morpholino Using Cyclic RGD Peptide

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Hironori Uehara; Santosh Kumar Muddana; Xiaohui Zhang; Subrata Kumar Das; Sai Bhuvanagiri; Jinlu Liu; Yuanyuan Wu; Susie Choi; Lara S. Carroll; Bonnie Archer; Balamurali K. Ambati

Trans. Vis. Sci. Tech.. 2017; 6(3):9. doi: https://doi.org/10.1167/tvst.6.3.9

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Comprehensive Molecular Screening in a cohort of Chinese patients with Leber Congenital Amaurosis or Severe early childhood onset retinal dystrophy

Yang Li; KE XU; Xiaohui Zhang; YUE XIE; FENG JIANG; LIJUAN LIU

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):666. doi:

ARVO Annual Meeting Abstract September 2016

Systemic Distribution of AAV10.COMPAng1 in the Ins2Akita mouse

Malkit Kaur Singh; Hironori Uehara; Xiaohui Zhang; Deepti Vashist; Lara Carroll; Bonnie Archer; Yufeng Huang; Balamurali Ambati

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5056. doi:

ARVO Annual Meeting Abstract September 2016

The Disruption of Collagen8A2 gene using CRISPR/CAS9 system to treat Fuch’s Dystrophy

Sai Santosh Kumar Bhuvanagiri; Balamurali Ambati; Hironori Uehara; Susie Choi; Xiaohui Zhang; Brain Bentley

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5298. doi:

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Phenotype-Based Genetic Analysis Reveals Missing Heritability of ABCA4 -Related Retinopathy: Deep Intronic Variants and Copy Number Variations

Gene knockdown of Col8a2 in mouse corneal endothelium by non-homologous end joint repair using adenovirus-mediated Crispr/Cas9

Phenotype-Based Genetic Analysis Reveals Missing Heritability of ABCA4 -Related Retinopathy: Deep Intronic Variants and Copy Number Variations

Subretinal Injection of AAVBR1 Targets the RPE and Outer Retina

Topical Pergolide Enhance Corneal Nerve Regrowth Following Induced Corneal Abrasion

Systemic Delivery Of Endothelial Colony Forming Cells Enables Vascular Integration Into Diabetic Mouse retinas, But Not Diabetic Mouse Retinas Treated With AAV2.COMP-Ang1

Gene therapy targeting PDGF-B for neovascular AMD

TTR mutations and clinical characteristics of patients with vitreous amyloidosis

Mutation Screening of OPA1 in a cohort Chinese patients with Suspected Autosomal Dominant Optic Atrophy

Intravitreal AAV2.COMP-Ang1 Attenuates Deep Capillary Plexus Expansion in the Aged Diabetic Mouse Retina

Sector Retinitis Pigmentosa caused by mutations of the RHO gene

Efficacy and Safety of AAV2.Flt23k Intraceptor Compared to AAV2.sFlt01

Comprehensive Molecular Screening in a Large Chinese Cohort with Usher Syndrome

Comprehensive Molecular Screening in Chinese Usher Syndrome Patients

Screening of BEST1 Gene in a Chinese Cohort With Best Vitelliform Macular Dystrophy or Autosomal Recessive Bestrophinopathy

Systemic Effects of AAV.COMPAng1 in the Ins2Akita Diabetic Mouse

Targeted Delivery of FLT-Morpholino Using Cyclic RGD Peptide

Comprehensive Molecular Screening in a cohort of Chinese patients with Leber Congenital Amaurosis or Severe early childhood onset retinal dystrophy

Systemic Distribution of AAV10.COMPAng1 in the Ins2Akita mouse

The Disruption of Collagen8A2 gene using CRISPR/CAS9 system to treat Fuch’s Dystrophy

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