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Lens April 2025

Elevated Inflammatory Cytokines Persist in the Aqueous Humor Years After Cataract Surgery

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Caili Hao; Emily Fan; Zongbo Wei; Kazi Rafsan Radeen; Neha Purohit; Kailin Li; Sharad Purohit; Xingjun Fan
TAGS: cataract, cataract surgery, chronic inflammation, cytokine, hypertension, surgical procedures, operative, aqueous humor, surgery specialty, donors
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):12. https://doi.org/10.1167/iovs.66.4.12

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Biodistribution of ovalbumin in the retina from a topical metal-organic framework-based drug delivery platform

Phillip Harding; Xin Fan; Ahmad Chaudhry; Morgan DiLeo

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3966.

ARVO Annual Meeting Abstract June 2024

A novel tear protein biomarker sampling method using a thermoresponsive ocular insert loaded with antibody-coated nanoparticles

Xin Fan; Morgan DiLeo

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6561.

ARVO Annual Meeting Abstract June 2024

Systemic exposure to UVB is sufficient to induce AMD: Characterization of a Novel Animal Model

Abdelhakim Mohamed Safwat Morsy; Valerie Harris; Yusra Zaidi; Xingjun Fan; Brian Stansfield

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):769.

ARVO Annual Meeting Abstract June 2024

Ultraviolet irradiation induces keratoconus-associated changes in the corneas of C57Bl/6J mice

Rachel Hadvina; Theresa Akoto; Skyler Jones; Xingjun Fan; Amy Estes; Yutao Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4553.

ARVO Annual Meeting Abstract June 2024

Glutathione Deficiency Alters Urea Efflux from the Lens

Elizabeth Rubeira; Billy Hayden; Alejandra Soto; David Sell; Zongbo WEI; Xingjun Fan; Vincent M Monnier; Jeremy A Whitson

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5046.

ARVO Annual Meeting Abstract June 2024

Lens epithelial cells mediated Wnt/b-catenin autocrine signaling promotes epithelium fibrosis

Xingjun Fan; Caili Hao; Zongbo WEI; Kazi Radeen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5020.

ARVO Annual Meeting Abstract June 2024

Deficiency in lipid peroxidation suppressor Gpx4 results in neonatal cataract formation in mice

Zongbo WEI; Caili Hao; Kazi Radeen; Xingjun Fan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):970.

ARVO Annual Meeting Abstract June 2023

Topically Gel/Microsphere System Loaded with Brimonidine/Timolol for Long-Term Glaucoma Treatment

Xin Fan; Morgan DiLeo

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2609.

ARVO Annual Meeting Abstract June 2023

Mouse deficiency with both gamma glutamate-cysteine ligase catalytic subunit (Gclc) and modifier subunit (Gclm) develops an early nuclear cataract

Zongbo WEI; Caili Hao; Vincent M Monnier; Xingjun Fan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1945.

ARVO Annual Meeting Abstract June 2023

Comparative whole transcriptome analysis of human lens epithelium with and without cataract surgery

Xingjun Fan; Zongbo WEI; Kazi Radeen; Xiang Zhang; Caili Hao

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4136.

Clinical and Epidemiologic Research November 2022

Vascular Changes of the Choroid and Their Correlations With Visual Acuity in Pathological Myopia

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Yiyi Wang; Sisi Chen; Jue Lin; Wen Chen; Huimin Huang; Xin Fan; Xinyuan Cao; Meixiao Shen; Jie Ye; Shuangqian Zhu; Anquan Xue; Fan Lu; Yilei Shao
TAGS: choroid, cortical blindness, myopia, visual acuity, eye
Invest. Ophthalmol. Vis. Sci.. 2022; 63(12):20. https://doi.org/10.1167/iovs.63.12.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

α-Crystallin chaperone mimetic small molecules as a paradigm for cataract prevention by inhibition of lens γ-crystallin aggregation

Vincent M Monnier; Sidra Islam; Michael Do; Brett Frank; Samuel G Wheeler; Xingjun Fan; Kirsten J Lampi; David R Sell

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):17.

ARVO Annual Meeting Abstract June 2022

Lipid peroxidation induces ferroptosis in the lens epithelium

Xingjun Fan; Zongbo Wei; Caili Hao; Jingru Huangfu; Ramkumar Srinivasagan; Xiang Zhang

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1146.

ARVO Annual Meeting Abstract June 2022

Mitotic Activation of Quiescent Lens Epithelial Cells Repairs UVB-Induced Capsular Cataracts

Zongbo WEI; Caili Hao; Xingjun Fan

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1143.

Lens December 2021

Mitotic Activation Around Wound Edges and Epithelialization Repair in UVB-Induced Capsular Cataracts

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Zongbo Wei; Caili Hao; Ramkumar Srinivasagan; Hongli Wu; Jian-Kang Chen; Xingjun Fan
TAGS: cataract, epithelialization, lens epithelial cell, ultraviolet b radiation, wounds and injuries, mice, lens capsule, crystalline, lens, crystalline, lens (device)
Invest. Ophthalmol. Vis. Sci.. 2021; 62(15):29. https://doi.org/10.1167/iovs.62.15.29

Includes: Supplemental Content

Glaucoma November 2021

Retinal Microcirculatory Responses to Hyperoxia in Primary Open-Angle Glaucoma Using Optical Coherence Tomography Angiography

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Xintong Fan; Huan Xu; Ruyi Zhai; Qilian Sheng; Xiangmei Kong
TAGS: angiogram, hyperoxia, open-angle glaucoma, optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2021; 62(14):4. https://doi.org/10.1167/iovs.62.14.4

Includes: Supplemental Content

Vision Sciences Society Annual Meeting Abstract September 2021

Configural processing in humans and deep convolutional neural networks

Shaiyan Keshvari; Xingye Fan; James H. Elder

Journal of Vision. 2021; 21(9):2887. https://doi.org/10.1167/jov.21.9.2887

ARVO Annual Meeting Abstract June 2021

Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells

Xingjun Fan; Jingru Huangfu; Cail Hao; Zongbo Wei; Michael Wormstone; Hong Yan

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2076.

ARVO Annual Meeting Abstract July 2019

ROS-mediated Wnt/β-catenin signaling in lens epithelial cells adaptation and posterior capsule opacification

Xingjun Fan; Zongbo Wei; Hong Yan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1124.

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Elevated Inflammatory Cytokines Persist in the Aqueous Humor Years After Cataract Surgery

Biodistribution of ovalbumin in the retina from a topical metal-organic framework-based drug delivery platform

A novel tear protein biomarker sampling method using a thermoresponsive ocular insert loaded with antibody-coated nanoparticles

Systemic exposure to UVB is sufficient to induce AMD: Characterization of a Novel Animal Model

Ultraviolet irradiation induces keratoconus-associated changes in the corneas of C57Bl/6J mice

Glutathione Deficiency Alters Urea Efflux from the Lens

Lens epithelial cells mediated Wnt/b-catenin autocrine signaling promotes epithelium fibrosis

Deficiency in lipid peroxidation suppressor Gpx4 results in neonatal cataract formation in mice

Topically Gel/Microsphere System Loaded with Brimonidine/Timolol for Long-Term Glaucoma Treatment

Mouse deficiency with both gamma glutamate-cysteine ligase catalytic subunit (Gclc) and modifier subunit (Gclm) develops an early nuclear cataract

Comparative whole transcriptome analysis of human lens epithelium with and without cataract surgery

Vascular Changes of the Choroid and Their Correlations With Visual Acuity in Pathological Myopia

α-Crystallin chaperone mimetic small molecules as a paradigm for cataract prevention by inhibition of lens γ-crystallin aggregation

Lipid peroxidation induces ferroptosis in the lens epithelium

Mitotic Activation of Quiescent Lens Epithelial Cells Repairs UVB-Induced Capsular Cataracts

Mitotic Activation Around Wound Edges and Epithelialization Repair in UVB-Induced Capsular Cataracts

Retinal Microcirculatory Responses to Hyperoxia in Primary Open-Angle Glaucoma Using Optical Coherence Tomography Angiography

Configural processing in humans and deep convolutional neural networks

Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells

ROS-mediated Wnt/β-catenin signaling in lens epithelial cells adaptation and posterior capsule opacification

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