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Retina August 2015

The Contribution of Genetic Architecture to the 10-Year Incidence of Age-Related Macular Degeneration in the Fellow Eye

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Masahiro Miyake; Kenji Yamashiro; Hiroshi Tamura; Kyoko Kumagai; Masaaki Saito; Masako Sugahara-Kuroda; Munemitsu Yoshikawa; Maho Oishi; Yumiko Akagi-Kurashige; Isao Nakata; Hideo Nakanishi; Norimoto Gotoh; Akio Oishi; Fumihiko Matsuda; Ryo Yamada; Chiea-Chuen Khor; Yasuo Kurimoto; Tetsuju Sekiryu; Akitaka Tsujikawa; Nagahisa Yoshimura
TAGS: age-related macular degeneration, eye, genes, genetics, incidence, genetic risk, cohort studies, single nucleotide polymorphism, cultural formulation interview, disease susceptibility
Invest. Ophthalmol. Vis. Sci.. 2015; 56(9):5353-5361. doi: https://doi.org/10.1167/iovs.14-16020

Includes: Supplemental Content

Genetics November 2014

Comprehensive Replication of the Relationship Between Myopia-Related Genes and Refractive Errors in a Large Japanese Cohort

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Munemitsu Yoshikawa; Kenji Yamashiro; Masahiro Miyake; Maho Oishi; Yumiko Akagi-Kurashige; Kyoko Kumagai; Isao Nakata; Hideo Nakanishi; Akio Oishi; Norimoto Gotoh; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura; for the Nagahama Study Group
TAGS: cohort studies, genes, japanese, myopia, refractive errors, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2014; 55(11):7343-7354. doi: https://doi.org/10.1167/iovs.14-15105

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

New Oral Therapy for Diabetic Macular Edema by Fidarestat

Atsushi Nakajima; Eiji Suzuki; Noriaki Kato; Takahito Jomori; Yoshio Akagi

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1065. doi:

ARVO Annual Meeting Abstract April 2014

Susceptibility genes for large drusen in Japanese

Kenji Yamashiro; Masahiro Miyake; Munemitsu Yoshikawa; Isao Nakata; Hideo Nakanishi; Yumiko Akagi; Kyoko Kumagai; Maho Oishi; Akitaka Tsujikawa; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2228. doi:

ARVO Annual Meeting Abstract April 2014

Genome-wide analysis for loci associated with the bilaterality of age-related macular degeneration

Kyoko Kumagai; Kenji Yamashiro; Masahiro Miyake; Munemitsu Yoshikawa; Isao Nakata; Yumiko Akagi-Kurashige; Akitaka Tsujikawa; Ching-Yu Cheng; Chiea chuen Khor; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2219. doi:

ARVO Annual Meeting Abstract April 2014

Replication analysis of myopia-associated genes in Japanese cohort and in highly myopic patients using genome-wide association study

Munemitsu Yoshikawa; Kenji Yamashiro; Masahiro Miyake; Maho Oishi; Yugo Kimura; Kyoko Kumagai; Yumiko Akagi-Kurashige; Hideo Nakanishi; Norimoto Gotoh; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3611. doi:

Retina March 2014

Three-Dimensional Optical Coherence Tomography Evaluation of Vascular Changes at Arteriovenous Crossings

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Kyoko Kumagai; Akitaka Tsujikawa; Yuki Muraoka; Yumiko Akagi-Kurashige; Tomoaki Murakami; Kazuaki Miyamoto; Ryo Yamada; Nagahisa Yoshimura
TAGS: diameter, fundus photography, optical coherence tomography, eye, hypertension, retinal vessels, compression
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1867-1875. doi: https://doi.org/10.1167/iovs.13-13303

Includes: Multimedia, Supplemental Content

Retina January 2014

Retinal Vessel Tortuosity Associated With Central Retinal Vein Occlusion: An Optical Coherence Tomography Study

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Yuki Muraoka; Akitaka Tsujikawa; Kyoko Kumagai; Yumiko Akagi-Kurashige; Ken Ogino; Tomoaki Murakami; Kazuaki Miyamoto; Nagahisa Yoshimura
TAGS: central retinal vein occlusion, eye, optical coherence tomography, retinal vessel tortuosity, retinal vessels, central retinal vein, retina, retinal vasculature
Invest. Ophthalmol. Vis. Sci.. 2014; 55(1):134-141. doi: https://doi.org/10.1167/iovs.13-13201

Genetics November 2013

Association Between ZIC2 , RASGRF1 , and SHISA6 Genes and High Myopia in Japanese Subjects

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Maho Oishi; Kenji Yamashiro; Masahiro Miyake; Yumiko Akagi-Kurashige; Kyoko Kumagai; Isao Nakata; Hideo Nakanishi; Munemitsu Yoshikawa; Akio Oishi; Norimoto Gotoh; Akitaka Tsujikawa; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura
TAGS: genes, japanese, myopia, ras protein specific guanine nucleotide releasing factor 1, single nucleotide polymorphism, choroidal neovascularization
Invest. Ophthalmol. Vis. Sci.. 2013; 54(12):7492-7497. doi: https://doi.org/10.1167/iovs.13-12825

Genetics September 2013

Association Between the Cholesteryl Ester Transfer Protein Gene and Polypoidal Choroidal Vasculopathy

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Isao Nakata; Kenji Yamashiro; Takahisa Kawaguchi; Norimoto Gotoh; Hideo Nakanishi; Yumiko Akagi-Kurashige; Masahiro Miyake; Akitaka Tsujikawa; Akio Oishi; Masaaki Saito; Tomohiro Iida; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura
TAGS: cholesterol ester transfer proteins, genes, vascular diseases, high density lipoprotein cholesterol
Invest. Ophthalmol. Vis. Sci.. 2013; 54(9):6068-6073. doi: https://doi.org/10.1167/iovs.13-11605

Retina June 2013

Evaluation of Pigment Epithelium–Derived Factor and Complement Factor I Polymorphisms as a Cause of Choroidal Neovascularization in Highly Myopic Eyes

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Masahiro Miyake; Kenji Yamashiro; Hideo Nakanishi; Isao Nakata; Yumiko Akagi-Kurashige; Kyoko Kumagai; Maho Oishi; Akitaka Tsujikawa; Muka Moriyama; Kyoko Ohno-Matsui; Manabu Mochizuki; Nagahisa Yoshimura
TAGS: choroidal neovascularization, complement factor i, cultural formulation interview, eye, pigment, polymorphism, epithelium, myopia, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2013; 54(6):4208-4212. doi: https://doi.org/10.1167/iovs.13-12280

ARVO Annual Meeting Abstract June 2013

Three-Dimensional Tomographic Features of Retinal Arteriovenous Crossings on Optical Coherence Tomography

Kyoko Kumagai; Akitaka Tsujikawa; Yuki Muraoka; Yumiko Akagi-Kurashige; Ken Ogino; Tomoaki Murakami; Kazuaki Miyamoto; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):25. doi:

ARVO Annual Meeting Abstract June 2013

Three-Dimensional Modeling of Highly Myopic Human Eyes Using Optical Coherence Tomography Imaging

Yumiko Akagi-Kurashige; Kenji Yamashiro; Masahiro Miyake; Akio Oishi; Akitaka Tsujikawa; Masanori Hangai; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5708. doi:

ARVO Annual Meeting Abstract June 2013

Heritability Estimation of Axial Length and Refractive Error Explained by Genome-Wide Single Nucleotide Polymorphisms

Masahiro Miyake; Kenji Yamashiro; Hideo Nakanishi; Isao Nakata; Yumiko Akagi-Kurashige; Kyoko Kumagai; Akitaka Tsujikawa; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura; Nagahama Study Group

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1734. doi:

Retina November 2012

Macular Choroidal Thickness Measured by Swept Source Optical Coherence Tomography in Eyes with Inferior Posterior Staphyloma

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Abdallah A. Ellabban; Akitaka Tsujikawa; Akiko Matsumoto; Kenji Yamashiro; Akio Oishi; Sotaro Ooto; Isao Nakata; Yumiko Akagi-Kurashige; Masahiro Miyake; Nagahisa Yoshimura
TAGS: choroid, eye, optical coherence tomography, staphyloma
Invest. Ophthalmol. Vis. Sci.. 2012; 53(12):7735-7745. doi: https://doi.org/10.1167/iovs.12-9952

Genetics September 2012

Association of Genetic Variants on 8p21 and 4q12 with Age-Related Macular Degeneration in Asian Populations

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Isao Nakata; Kenji Yamashiro; Yumiko Akagi-Kurashige; Masahiro Miyake; Kyoko Kumagai; Akitaka Tsujikawa; Ke Liu; Li Jia Chen; David T. L. Liu; Timothy Y. Y. Lai; Yoichi Sakurada; Seigo Yoneyama; Ching-Yu Cheng; Peter Cackett; Ian Y. Yeo; Wan Ting Tay; Belinda K. Cornes; Eranga N. Vithana; Tin Aung; Keitaro Matsuo; Fumihiko Matsuda; Tien-Yin Wong; Hiroyuki Iijima; Chi Pui Pang; Nagahisa Yoshimura
TAGS: age-related macular degeneration, asian, cohort studies, exudative age-related macular degeneration, genetics, japanese, chinese (other dialects), choroidal neovascularization, chinese people, meta-analysis
Invest. Ophthalmol. Vis. Sci.. 2012; 53(10):6576-6581. doi: https://doi.org/10.1167/iovs.12-10219

Retina April 2012

Vascular Endothelial Growth Factor Gene Polymorphisms and Choroidal Neovascularization in Highly Myopic Eyes

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Yumiko Akagi-Kurashige; Kyoko Kumagai; Kenji Yamashiro; Hideo Nakanishi; Isao Nakata; Masahiro Miyake; Akitaka Tsujikawa; Muka Moriyama; Kyoko Ohno-Matsui; Manabu Mochizuki; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura
TAGS: choroidal neovascularization, eye, genes, polymorphism, vascular endothelial growth factor a
Invest. Ophthalmol. Vis. Sci.. 2012; 53(4):2349-2353. doi: https://doi.org/10.1167/iovs.11-9405

ARVO Annual Meeting Abstract March 2012

Prevalence of AMD in the Japanese: The Nagahama Study

Isao Nakata; Kenji Yamashiro; Hideo Nakanishi; Hisako Hayashi; Masahiro Miyake; Yumiko Akagi-Kurashige; Akitaka Tsujikawa; Atsushi Otani; Fumihiko Matsuda; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3807. doi:

ARVO Annual Meeting Abstract March 2012

VEGF Polymorphisms And Choroidal Neovascularization In Highly Myopic Eyes

Kyoko Kumagai; Kenji Yamashiro; Masahiro Miyake; Yumiko Akagi-Kurashige; Isao Nakata; Akio Oishi; Akitaka Tsujikawa; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4440. doi:

ARVO Annual Meeting Abstract March 2012

Shapes of Posterior Pole Associated with Retinoschisis in Highly Myopic Eyes

Tatsuya Yoshitake; Kenji Yamashiro; Masahiro Miyake; Yumiko Akagi-Kurashige; Akio Oishi; Akitaka Tsujikawa; Masanori Hangai; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4455. doi:

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The Contribution of Genetic Architecture to the 10-Year Incidence of Age-Related Macular Degeneration in the Fellow Eye

Comprehensive Replication of the Relationship Between Myopia-Related Genes and Refractive Errors in a Large Japanese Cohort

New Oral Therapy for Diabetic Macular Edema by Fidarestat

Susceptibility genes for large drusen in Japanese

Genome-wide analysis for loci associated with the bilaterality of age-related macular degeneration

Replication analysis of myopia-associated genes in Japanese cohort and in highly myopic patients using genome-wide association study

Three-Dimensional Optical Coherence Tomography Evaluation of Vascular Changes at Arteriovenous Crossings

Retinal Vessel Tortuosity Associated With Central Retinal Vein Occlusion: An Optical Coherence Tomography Study

Association Between ZIC2 , RASGRF1 , and SHISA6 Genes and High Myopia in Japanese Subjects

Association Between the Cholesteryl Ester Transfer Protein Gene and Polypoidal Choroidal Vasculopathy

Evaluation of Pigment Epithelium–Derived Factor and Complement Factor I Polymorphisms as a Cause of Choroidal Neovascularization in Highly Myopic Eyes

Three-Dimensional Tomographic Features of Retinal Arteriovenous Crossings on Optical Coherence Tomography

Three-Dimensional Modeling of Highly Myopic Human Eyes Using Optical Coherence Tomography Imaging

Heritability Estimation of Axial Length and Refractive Error Explained by Genome-Wide Single Nucleotide Polymorphisms

Macular Choroidal Thickness Measured by Swept Source Optical Coherence Tomography in Eyes with Inferior Posterior Staphyloma

Association of Genetic Variants on 8p21 and 4q12 with Age-Related Macular Degeneration in Asian Populations

Vascular Endothelial Growth Factor Gene Polymorphisms and Choroidal Neovascularization in Highly Myopic Eyes

Prevalence of AMD in the Japanese: The Nagahama Study

VEGF Polymorphisms And Choroidal Neovascularization In Highly Myopic Eyes

Shapes of Posterior Pole Associated with Retinoschisis in Highly Myopic Eyes

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