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Articles June 2022

Two-Year Choroidal Thickness Attenuation and Its Associations in Healthy Chinese Adults

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Wenjia Cai; Xiao Guo; Wei Wang; Kun Xiong; Xiaotong Han; Xia Gong; Meng Yuan; Yuting Li; Xiaoling Liang; Yizhi Liu; Wenyong Huang
TAGS: adult, attenuation, chinese (other dialects), chinese people, eye, longitudinal studies
Trans. Vis. Sci. Tech.. 2022; 11(6):21. doi: https://doi.org/10.1167/tvst.11.6.21

Includes: Supplemental Content

Articles June 2022

An Artificial-Intelligence–Based Automated Grading and Lesions Segmentation System for Myopic Maculopathy Based on Color Fundus Photographs

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Jia Tang; Mingzhen Yuan; Kaibin Tian; Yuelin Wang; Dongyue Wang; Jingyuan Yang; Zhikun Yang; Xixi He; Yan Luo; Ying Li; Jie Xu; Xirong Li; Dayong Ding; Yanhan Ren; Youxin Chen; Srinivas R. Sadda; Weihong Yu
TAGS: artificial intelligence, color, fundus photography, grading system, macular disorders, atrophy, myopic macular degeneration
Trans. Vis. Sci. Tech.. 2022; 11(6):16. doi: https://doi.org/10.1167/tvst.11.6.16

Includes: Supplemental Content

Articles June 2022

Quantitative Assessment of Biomechanical Properties of the Human Keratoconus Cornea Using Acoustic Radiation Force Optical Coherence Elastography

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Yanzhi Zhao; Hongwei Yang; Yingjie Li; Yongbo Wang; Xiao Han; Yirui Zhu; Yubao Zhang; Guofu Huang
TAGS: cornea, elasticity imaging techniques, keratoconus, acoustics, optics, radiation, elasticity
Trans. Vis. Sci. Tech.. 2022; 11(6):4. doi: https://doi.org/10.1167/tvst.11.6.4

Genetics June 2022

Phenotype-Based Genetic Analysis Reveals Missing Heritability of ABCA4 -Related Retinopathy: Deep Intronic Variants and Copy Number Variations

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Lu Tian; Chunjie Chen; Yuning Song; Xiaohui Zhang; Ke Xu; Yue Xie; Zi-Bing Jin; Yang Li
TAGS: abca4 gene, alleles, copy number polymorphism, genetic analysis, introns, phenotype, retinal diseases
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):5. doi: https://doi.org/10.1167/iovs.63.6.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Discovery and preclinical development of VVN539，a novel ROCK and NO dual MOA agent for the treatment of glaucoma in normotensive rabbits model with minimal hyperemia.

Yong Li; Lili Yao; Kuifeng Dang; Qiao Han; Caroline Lu; Erning Xia; Wang Shen

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):150 – A0343. doi:

ARVO Annual Meeting Abstract June 2022

Deciphering non-coding genetic variants via integrative single cell multi-omics analysis

Rui Chen; Jun Wang; Xuesen Cheng; Qingnan Liang; Jun Wang; Margaret M DeAngelis; Yumei Li

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3. doi:

ARVO Annual Meeting Abstract June 2022

SZN-413, a monospecific Fzd4 Agonist as a Potential Novel Therapeutic for the Treatment of Diabetic Retinopathy

Huy Nguyen; Sungjin Lee; Elizabeth Whisler; Kelsey Logas; Hui Chen; Partha Sampathkumar; Jay Ye; Nick Suen; Yang Li; Wen-Chen Yeh

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):668 – F0122. doi:

ARVO Annual Meeting Abstract June 2022

Long-read high-throughput sequencing uncovers rare structural variations in syndromic optic atrophy

Ren-Juan Shen; Yang Li; Zi-Bing Jin

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):502 – A0079. doi:

ARVO Annual Meeting Abstract June 2022

Rhesus macaques with soft drusen share susceptibility genes with age-related macular degeneration in humans.

Glenn Yiu; Jun Wang; Yumei Li; Kevin Choy; Sina Farsiu; Leon Huynh; Karolina Paulina Roszak; Ala Moshiri; Sara M Thomasy; Rui Chen

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1493. doi:

ARVO Annual Meeting Abstract June 2022

Anterior topographic limbal demarcation with ultrawide-field OCT

Clara Llorens Quintana; Siyu Chen; JUNHONG Lin; James G Fujimoto; Yan Li; David Huang

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1195 – A0195. doi:

ARVO Annual Meeting Abstract June 2022

Development of Dual-PCDH15 AAV Gene Therapy for Usher Syndrome Type 1F Blindness and Deafness

Maryna Ivanchenko; Daniel Hathaway; Eric Mulhall; Mantian Wang; Alex Klein; Yaqiao Li; Bence György; David Corey

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1110. doi:

ARVO Annual Meeting Abstract June 2022

Lipid surface area, emulsion stability and clinical performance of Blink ® Triple Care lipid eye drop

Yongcheng Li; Meredith Bishop; Aliaksandr Zhuk; Jeffrey Martin

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1987 – A0317. doi:

ARVO Annual Meeting Abstract June 2022

Retinoblastoma Organoids Generated from Patient-derived Induced Pluripotent Stem cells.

Yanping Li; Li-Wen Jin; Ya-Ting Wang; Wen Wang; XIAO ZHANG; Kang-Xin Jin; Zi-Bing Jin

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2335 – A0004. doi:

ARVO Annual Meeting Abstract June 2022

Single-cell Multiomics Analysis of Human Retinal Development

Zhen Zuo; Xuesen Cheng; Yumei Li; Salma Ferdous; Jin Li; Antonio Jacobo Lopez; Ala Moshiri; Rui Chen

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2313. doi:

ARVO Annual Meeting Abstract June 2022

A single cell multi-omics atlas of the human retina

Xuesen Cheng; Qingnan Liang; Jun Wang; Leah A Owen; Yumei Li; Margaret M DeAngelis; Rui Chen

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2311. doi:

ARVO Annual Meeting Abstract June 2022

Phenotype-Based Genetic Analysis Reveals Missing Heritability of ABCA4 -Related Retinopathy: Deep Intronic Variants and Copy Number Variations

tian lu; chunjie chen; yuning song; xiaohui zhang; ke xu; Yue Xie; Zi-Bing Jin; Yang Li

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2624. doi:

ARVO Annual Meeting Abstract June 2022

The role of light in the pathogenesis of rhodopsin retinitis pigmentosa

Rosellina Guarascio; Kwan Hau; Rowan Asfahani; Kalliopi Ziaka; Hannah Poultney; Dimitra Athanasiou; Monica Aguila; Yumei Li; Rui Chen; Michael E Cheetham

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3816. doi:

ARVO Annual Meeting Abstract June 2022

A spontaneous nonhuman primate model of myopic foveoschisis.

Tzu-Ni Sin; Sangbae Kim; Yumei Li; Rui Chen; Sook Hyun Chung; Soohyun Kim; Isabel Casanova; Sangwan Park; Ori Pomerantz; Jeffrey Roberts; Sara M Thomasy; Ala Moshiri; Robert B. Hufnagel; Paul A Sieving; Glenn Yiu

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3754 – F0175. doi:

ARVO Annual Meeting Abstract June 2022

Activin A limits VEGF-induced permeability

Basma Baccouche; Lina Lietuvninkas; Yueru Li; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3602 – A0057. doi:

ARVO Annual Meeting Abstract June 2022

Hyperglycemia alters VEGF-induced permeability in retinal endothelial cells

Maximilian McCann; Yueru Li; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3594 – A0049. doi:

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Two-Year Choroidal Thickness Attenuation and Its Associations in Healthy Chinese Adults

An Artificial-Intelligence–Based Automated Grading and Lesions Segmentation System for Myopic Maculopathy Based on Color Fundus Photographs

Quantitative Assessment of Biomechanical Properties of the Human Keratoconus Cornea Using Acoustic Radiation Force Optical Coherence Elastography

Phenotype-Based Genetic Analysis Reveals Missing Heritability of ABCA4 -Related Retinopathy: Deep Intronic Variants and Copy Number Variations

Discovery and preclinical development of VVN539，a novel ROCK and NO dual MOA agent for the treatment of glaucoma in normotensive rabbits model with minimal hyperemia.

Deciphering non-coding genetic variants via integrative single cell multi-omics analysis

SZN-413, a monospecific Fzd4 Agonist as a Potential Novel Therapeutic for the Treatment of Diabetic Retinopathy

Long-read high-throughput sequencing uncovers rare structural variations in syndromic optic atrophy

Rhesus macaques with soft drusen share susceptibility genes with age-related macular degeneration in humans.

Anterior topographic limbal demarcation with ultrawide-field OCT

Development of Dual-PCDH15 AAV Gene Therapy for Usher Syndrome Type 1F Blindness and Deafness

Lipid surface area, emulsion stability and clinical performance of Blink ® Triple Care lipid eye drop

Retinoblastoma Organoids Generated from Patient-derived Induced Pluripotent Stem cells.

Single-cell Multiomics Analysis of Human Retinal Development

A single cell multi-omics atlas of the human retina

Phenotype-Based Genetic Analysis Reveals Missing Heritability of ABCA4 -Related Retinopathy: Deep Intronic Variants and Copy Number Variations

The role of light in the pathogenesis of rhodopsin retinitis pigmentosa

A spontaneous nonhuman primate model of myopic foveoschisis.

Activin A limits VEGF-induced permeability

Hyperglycemia alters VEGF-induced permeability in retinal endothelial cells

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