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Retinal Cell Biology June 2017

Vascular Adhesion Protein-1 Blockade Suppresses Ocular Inflammation After Retinal Laser Photocoagulation in Mice

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Takashi Matsuda; Kousuke Noda; Miyuki Murata; Akiko Kawasaki; Atsuhiro Kanda; Yukihiko Mashima; Susumu Ishida
TAGS: amine oxidase (copper-containing), lasers, light coagulation, proteins, adhesions, mice, eye inflammation
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3254-3261. doi: https://doi.org/10.1167/iovs.17-21555

Retina December 2016

Long-Term Protection of Genetically Ablated Rabbit Retinal Degeneration by Sustained Transscleral Unoprostone Delivery

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Nobuhiro Nagai; Eri Koyanagi; Yasuko Izumida; Junjun Liu; Aya Katsuyama; Hirokazu Kaji; Matsuhiko Nishizawa; Noriko Osumi; Mineo Kondo; Hiroko Terasaki; Yukihiko Mashima; Toru Nakazawa; Toshiaki Abe
TAGS: oryctolagus cuniculus, retinal degeneration, unoprostone isopropyl, electroretinography, retina, rna-directed dna polymerase, eye, polymerase chain reaction, in situ hybridization, placebos
Invest. Ophthalmol. Vis. Sci.. 2016; 57(15):6527-6538. doi: https://doi.org/10.1167/iovs.16-20453

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Protective Effects of Sustained Unoprostone Release Device in Rhodopsin Pro347Leu Transgenic Rabbits

Nobuhiro Nagai; Yasuko Izumida; Hirokazu Kaji; Matsuhiko Nishizawa; Aya Katsuyama; Shinji Yamada; Toru Nakazawa; Mineo Kondo; Hiroko Terasaki; Yukihiko Mashima; Toshiaki Abe

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4017. doi:

ARVO Annual Meeting Abstract June 2015

Pharmacokinetic and Safety Evaluation of a Transscleral Sustained Unoprostone Release Device

Nobuhiro Nagai; Yasuko Izumida; Eri Koyanagi; Hirokazu Kaji; Matsuhiko Nishizawa; Takahito Imagawa; Akiko Morikawa; Toru Nakazawa; Yukihiko Mashima; Toshiaki Abe

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4153. doi:

ARVO Annual Meeting Abstract April 2014

Controlled Transscleral Dual-drug Delivery by a Polymeric Device Reduces Light-induced Retinal Damage

Nobuhiro Nagai; Hirokazu Kaji; Zhaleh Kashkouli Nezhad; Kaori Sampei; Satoru Iwata; Matsuhiko Nishizawa; Yukihiko Mashima; Toshiaki Abe

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):446. doi:

ARVO Annual Meeting Abstract June 2013

Protective Effects of Transscleral Drug Delivery Device Against Photoreceptor Cell Death in S334ter Rhodopsin Mutant Rats

Nobuhiro Nagai; Hirokazu Kaji; Hideyuki Onami; Takuya Yamada; Yuki Katsukura; Yumi Ishikawa; Matsuhiko Nishizawa; Yukihiko Mashima; Toshiaki Abe

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5064. doi:

Retinal Cell Biology June 2012

Soluble Vascular Adhesion Protein-1 Accumulates in Proliferative Diabetic Retinopathy

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Miyuki Murata; Kousuke Noda; Junichi Fukuhara; Atsuhiro Kanda; Satoru Kase; Wataru Saito; Yoko Ozawa; Satsuki Mochizuki; Shioko Kimura; Yukihiko Mashima; Yasunori Okada; Susumu Ishida
TAGS: adhesions, blood capillaries, endothelial cells, glucose, proliferative diabetic retinopathy, proteins, cytokine, vitreous body, tumor necrosis factors
Invest. Ophthalmol. Vis. Sci.. 2012; 53(7):4055-4062. doi: https://doi.org/10.1167/iovs.12-9857

ARVO Annual Meeting Abstract April 2011

Microperimetry Shows Protection of Central Vision in Retinitis Pigmentosa Patients treated with UF-021: a Phase 2 Study (JapicCTI-090748)

Shuichi Yamamoto; Takeshi Sugawara; Mitsuru Nakazawa; Shigeki Machida; Akira Murakami; Nobuhisa Nao-i; Yuko Wada; Yozo Miyake; Yukihiko Mashima

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4992. doi:

ARVO Annual Meeting Abstract April 2011

Humphrey Perimetry 10-2 (JapicCTI-090748) assessment of Retinitis Pigmentosa Patients in Phase 2 Study of UF-021

Takeshi Sugawara; Shuichi Yamamoto; Mitsuru Nakazawa; Shigeki Machida; Akira Murakami; Nobuhisa Naoi; Yoko Wada; Yozo Miyake; Yukihiko Mashima

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4994. doi:

ARVO Annual Meeting Abstract April 2010

Role of Vascular Adhesion Protein-1 on Leukocyte Transmigration in Diabetic Retina

K. Noda; S. Nakao; S. Zandi; Y. Mashima; A. Hafezi-Moghadam

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):111. doi:

ARVO Annual Meeting Abstract April 2009

Vascular Adhesion Protein-1 Regulates Leukocyte Transmigration Rate in the Retina During Diabetes

K. Noda; S. Nakao; S. Zandi; Y. Mashima; A. Hafezi-Moghadam

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):5895. doi:

ARVO Annual Meeting Abstract May 2008

Vascular Adhesion Protein-1 Blockade Suppresses Choroidal Neovascularization

K. Noda; H. She; T. Nakazawa; T. Hisatomi; S. Nakao; L. Almulki; J. W. Miller; E. S. Gragoudas; Y. Mashima; A. Hafezi-Moghadam

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):539. doi:

ARVO Annual Meeting Abstract May 2008

Localization of Vascular Adhesion Protein-1 in Human Ocular Tissues

A. Hafezi-Moghadam; L. Almulki; K. Noda; T. Hisatomi; S. Nakao; Y. Mashima; S. Mallemadugula; F. Tayyari; N. Michaud; K. L. Thomas

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):950. doi:

ARVO Annual Meeting Abstract May 2008

Topical Administration of Unoprostone Provides Retinal Protection Against Retinal Degeneration of Rhodopsin P23h Rats by Inhibiting Apoptosis

T. Ito; M. Nakazawa; T. Metoki; H. Yamazaki; F. Ishikawa; K. Takeuchi; Y. Yokoi; H. Ohguro; Y. Mashima

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):2194. doi:

ARVO Annual Meeting Abstract May 2007

Expression of Vascular Adhesion Protein-1 in Ocular Tissues of Endotoxin-Induced Uveitis

K. L. Thomas; K. Noda; S. Miyahara; T. Nakazawa; T. Hisatomi; J. W. Miller; E. S. Gragoudas; Y. Kawai; Y. Mashima; A. Hafezi-Moghadam

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):5162. doi:

ARVO Annual Meeting Abstract May 2007

Screening for Candidate Genes for Open-angle Glaucoma on Chromosome 2

N. Fuse; Y. Mashima; M. Mengkegale; T. Funayama; A. Miyazawa; K. Nishida

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):5603. doi:

Glaucoma December 2006

SNPs and Interaction Analyses of Noelin 2, Myocilin, and Optineurin Genes in Japanese Patients with Open-Angle Glaucoma

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Tomoyo Funayama; Yukihiko Mashima; Yuichiro Ohtake; Karin Ishikawa; Nobuo Fuse; Noriko Yasuda; Takeo Fukuchi; Akira Murakami; Yoshihiro Hotta; Naoki Shimada; for The Glaucoma Gene Research Group
TAGS: genes, glaucoma, intraocular pressure, japanese, myoc gene, open-angle glaucoma, optn gene, raised intraocular pressure, single nucleotide polymorphism, gene interaction
Invest. Ophthalmol. Vis. Sci.. 2006; 47(12):5368-5375. doi: https://doi.org/10.1167/iovs.06-0196

ARVO Annual Meeting Abstract May 2006

Involvement of Insulin–Like Growth Factor–I and Insulin–Like Growth Factor Binding Protein–3 in Corneal Fibroblasts During Corneal Wound Healing

D. Kurosaka; K. Izumi; Y. Mashima; K. Tsubota

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):5030. doi:

Cornea February 2006

Involvement of Insulin-like Growth Factor-I and Insulin-like Growth Factor Binding Protein-3 in Corneal Fibroblasts during Corneal Wound Healing

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Kanako Izumi; Daijiro Kurosaka; Takeshi Iwata; Yoshihisa Oguchi; Yasuhiko Tanaka; Yukihiko Mashima; Kazuo Tsubota
TAGS: cornea, fibroblasts, insulin-like growth factor binding protein 3, insulin-like growth factor i, proteins, rna, messenger, wound healing, dna chemical synthesis
Invest. Ophthalmol. Vis. Sci.. 2006; 47(2):591-598. doi: https://doi.org/10.1167/iovs.05-0097

Glaucoma June 2005

Genetic Polymorphisms in the Angiotensin II Receptor Gene and Their Association with Open-Angle Glaucoma in a Japanese Population

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Kouhei Hashizume; Yukihiko Mashima; Tomoyo Fumayama; Yuichiro Ohtake; Itaru Kimura; Kazuhide Yoshida; Karin Ishikawa; Noriko Yasuda; Takuro Fujimaki; Ryo Asaoka; Takahisa Koga; Takashi Kanamoto; Takeo Fukuchi; Koichi Miyaki
TAGS: genes, genotype, glaucoma, intraocular pressure, japanese, open-angle glaucoma, polymorphism, receptor, angiotensin ii, angiotensin receptor antagonists
Invest. Ophthalmol. Vis. Sci.. 2005; 46(6):1993-2001. doi: https://doi.org/10.1167/iovs.04-1100

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Vascular Adhesion Protein-1 Blockade Suppresses Ocular Inflammation After Retinal Laser Photocoagulation in Mice

Long-Term Protection of Genetically Ablated Rabbit Retinal Degeneration by Sustained Transscleral Unoprostone Delivery

Protective Effects of Sustained Unoprostone Release Device in Rhodopsin Pro347Leu Transgenic Rabbits

Pharmacokinetic and Safety Evaluation of a Transscleral Sustained Unoprostone Release Device

Controlled Transscleral Dual-drug Delivery by a Polymeric Device Reduces Light-induced Retinal Damage

Protective Effects of Transscleral Drug Delivery Device Against Photoreceptor Cell Death in S334ter Rhodopsin Mutant Rats

Soluble Vascular Adhesion Protein-1 Accumulates in Proliferative Diabetic Retinopathy

Microperimetry Shows Protection of Central Vision in Retinitis Pigmentosa Patients treated with UF-021: a Phase 2 Study (JapicCTI-090748)

Humphrey Perimetry 10-2 (JapicCTI-090748) assessment of Retinitis Pigmentosa Patients in Phase 2 Study of UF-021

Role of Vascular Adhesion Protein-1 on Leukocyte Transmigration in Diabetic Retina

Vascular Adhesion Protein-1 Regulates Leukocyte Transmigration Rate in the Retina During Diabetes

Vascular Adhesion Protein-1 Blockade Suppresses Choroidal Neovascularization

Localization of Vascular Adhesion Protein-1 in Human Ocular Tissues

Topical Administration of Unoprostone Provides Retinal Protection Against Retinal Degeneration of Rhodopsin P23h Rats by Inhibiting Apoptosis

Expression of Vascular Adhesion Protein-1 in Ocular Tissues of Endotoxin-Induced Uveitis

Screening for Candidate Genes for Open-angle Glaucoma on Chromosome 2

SNPs and Interaction Analyses of Noelin 2, Myocilin, and Optineurin Genes in Japanese Patients with Open-Angle Glaucoma

Involvement of Insulin–Like Growth Factor–I and Insulin–Like Growth Factor Binding Protein–3 in Corneal Fibroblasts During Corneal Wound Healing

Involvement of Insulin-like Growth Factor-I and Insulin-like Growth Factor Binding Protein-3 in Corneal Fibroblasts during Corneal Wound Healing

Genetic Polymorphisms in the Angiotensin II Receptor Gene and Their Association with Open-Angle Glaucoma in a Japanese Population

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