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Immunology and Microbiology April 2025

Application of Metagenomic Long-Read Sequencing for the Diagnosis of Herpetic Uveitis

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Yoshito Koyanagi; Ai Fujita Sajiki; Kenya Yuki; Hiroaki Ushida; Kenichi Kawano; Kosuke Fujita; Hideyuki Shimizu; Daishi Okuda; Mitsuki Kosaka; Kazuhisa Yamada; Ayana Suzumura; Shu Kachi; Hiroki Kaneko; Hiroyuki Komatsu; Yoshihiko Usui; Hiroshi Goto; Koji M. Nishiguchi
TAGS: reading (activity), uveitis, metagenomic sequencing, nanopores, fluid flow
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):50. https://doi.org/10.1167/iovs.66.4.50

Includes: Supplemental Content

Immunology and Microbiology March 2025

An Approach to Predict Intraocular Diseases by Machine Learning Based on Vitreous Humor Immune Mediator Profile

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Risa Sugawara; Yoshihiko Usui; Akira Saito; Naoya Nezu; Hiroyuki Komatsu; Kinya Tsubota; Masaki Asakage; Naoyuki Yamakawa; Yoshihiro Wakabayashi; Masahiro Sugimoto; Masahiko Kuroda; Hiroshi Goto
TAGS: biological response modifiers, immune mediator, machine learning, vitreous body
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):38. https://doi.org/10.1167/iovs.66.3.38

ARVO Annual Meeting Abstract June 2024

MicroRNA Profiling in Extracellular Vesicles from Vitreous Humor and Serum of Patients with Ocular Sarcoidosis and Vitreoretinal Lymphoma

Hiroyuki Komatsu; Yoshihiko Usui; Yusuke Yoshioka; Masaki Asakage; Risa Sugawara; Kinya Tsubota; Ryo Wakita; Keiko Maruo; Takahiro Ochiya; Hiroshi Goto

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1473.

ARVO Annual Meeting Abstract June 2024

Clinical risk factors contributing to elongation of axial length in Vogt-Koyanagi-Harada disease

Sorano Tomimitsu; Kinya Tsubota; Mizuki Nakamura; Kazusa Koyama; Yoshihiko Usui; Yuto Kinoshita; Masaki Asakage; Chihiro Maehara; Ryota Nonaka; Risa Sugawara; Kei Wakatsuki; Hiroshi Goto

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3018.

ARVO Annual Meeting Abstract June 2024

Association of Merkel cell polyomavirus and clinicopathological findings in primary eyelid Merkel cell carcinomas

Yoshihiko Usui; Hiroyuki Komatsu; Yamamoto Yoshinari; Shinichiro Ohno; Keisuke Goto; Masahiko Kuroda; Toshitaka Nagao; Hiroshi Goto

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4092.

Anatomy and Pathology/Oncology December 2023

Vitreous Humor Proteomic Profile in Patients With Vitreoretinal Lymphoma

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Hiroyuki Komatsu; Yoshihiko Usui; Kinya Tsubota; Risa Fujii; Takefumi Yamaguchi; Kazuichi Maruyama; Ryo Wakita; Masaki Asakage; Kazuki Hamada; Naoyuki Yamakawa; Naoya Nezu; Koji Ueda; Hiroshi Goto
TAGS: primary vitreoretinal lymphoma, proteins, vitreous body, ocular sarcoidosis
Invest. Ophthalmol. Vis. Sci.. 2023; 64(15):2. https://doi.org/10.1167/iovs.64.15.2

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Clinical factors related to low prevalence of Fuchs’ uveitis syndrome in Japan

Yu yoneda; Yoshihiko Usui; Rie Tanaka; Kenichi Namba; Hiroshi Takase; Sentaro Kusuhara; Nobuyo Yawata; Yosuke Harada; Ryoji Yanai; Kazuichi Maruyama; Kei Nakai; Toshikatsu Kaburaki; Yujiro Fujino; Masaki Takeuchi; Masaru Takeuchi

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):OD5.

ARVO Annual Meeting Abstract June 2022

Adalimumab Treatment for Recurrence of Ocular Inflammation in Patients with Vogt-Koyanagi-Harada Disease: a multicenter study

Masaru Takeuchi; Shunsaku Nakai; Yoshihiko Usui; Kenichi Namba; Kayo Suzuki; Yosuke Harada; Sentaro Kusuhara; Toshikatsu Kaburaki; Rie Tanaka; Masaki Takeuchi; Nobuhisa Mizuki; Kei Nakai; Hiroshi Goto; Carl Herbort

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3192 – A0418.

Anatomy and Pathology/Oncology January 2021

Differential Tissue Metabolic Signatures in IgG4-Related Ophthalmic Disease and Orbital Mucosa-Associated Lymphoid Tissue Lymphoma

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Hiroyuki Shimizu; Yoshihiko Usui; Ryo Wakita; Yasuko Aita; Atsumi Tomita; Kinya Tsubota; Masaki Asakage; Naoya Nezu; Hiroyuki Komatsu; Kazuhiko Umazume; Masahiro Sugimoto; Hiroshi Goto

Invest. Ophthalmol. Vis. Sci.. 2021; 62(1):15. https://doi.org/10.1167/iovs.62.1.15

Includes: Supplemental Content

Immunology and Microbiology September 2020

Comprehensive miRNA Analysis Using Serum From Patients With Noninfectious Uveitis

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Masaki Asakage; Yoshihiko Usui; Naoya Nezu; Hiroyuki Shimizu; Kinya Tsubota; Naoyuki Yamakawa; Masakatsu Takanashi; Masahiko Kuroda; Hiroshi Goto
TAGS: micrornas, uveitis
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):4. https://doi.org/10.1167/iovs.61.11.4

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Role of microglia in the formation of subretinal neovascularization in Vldlr -/ - mice

Edith Aguilar; Ayumi Ouchi; Yoshihiko Usui; Toshihide Kurihara; Michael Dorrell; Yoichiro Ideguchi; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5403.

Multidisciplinary Ophthalmic Imaging August 2019

Evaluation of Retinal Pigment Epithelium Layer Change in Vogt-Koyanagi-Harada Disease With Multicontrast Optical Coherence Tomography

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Masahiro Miura; Shuichi Makita; Shinnosuke Azuma; Yoshiaki Yasuno; Satoshi Sugiyama; Toshihiro Mino; Tatsuo Yamaguchi; Tetsuya Agawa; Takuya Iwasaki; Yoshihiko Usui; Narsing A. Rao; Hiroshi Goto
TAGS: diagnostic imaging, eye, melanins, optical coherence tomography, retinal pigment epithelium, uveomeningoencephalitic syndrome, multimodal imaging
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3352-3362. https://doi.org/10.1167/iovs.19-27378

ARVO Annual Meeting Abstract July 2019

Cell population having a resistance to melanoma antigen specific T cell in uveal melanoma

Kinya Tsubota; Yoshihiko Usui; Hiroshi Goto

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):735.

ARVO Annual Meeting Abstract July 2019

Epidemiology of epiretinal membrane and macular edema in a large cohort of patients with uveitis

Chihiro Yanagida; Yoshihiko Usui; Ryosuke Mitsuhashi; Kinya Tsubota; naoya nezu; Takeshi Kezuka; Hiroshi Goto

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6679.

ARVO Annual Meeting Abstract July 2019

Association Between Axial Length and Uveitis

Marina Ogawa; Yoshihiko Usui; Kinya Tsubota; Jun-ichi Sakai; Hiroshi Goto

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6692.

ARVO Annual Meeting Abstract July 2019

TRPM2 gene deficiency promotes the growth of laser-induced choroidal neovascularization in mice.

KOSUKE NISHI; HIroki Iwanishi; Yuta Usui; Takayoshi Sumioka; Masayasu Miyajima; Yuka Okada; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1258.

ARVO Annual Meeting Abstract July 2019

Comprehensive genetic analysis of IgG4-related ophthalmic diseases by RNA sequencing

Masaki Asakage; Yoshihiko Usui; Marina Ogawa; Naoyuki Yamakawa; Kazuhiko Umazume; Rei Nemoto; Hiroshi Goto; Naoya Nezu; Masahiko Kuroda

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3434.

ARVO Annual Meeting Abstract July 2019

Efficacy of infliximab and adalimumab for macular edema associated with uveitis

Keiko Fujii; Yoshihiko Usui; Chihiro Maehara; Kinya Tsubota; Ryosuke Mitsuhashi; Akihiko Umazume; Takeshi Kezuka; Jun-ichi Sakai; Hiroshi Goto

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3521.

ARVO Annual Meeting Abstract July 2019

Outcome of vitrectomy for retinal hemangioma

Kazuhiko Umazume; Yoshihiro Wakabayashi; Yoshihiko Usui; Hiroshi Goto

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3549.

ARVO Annual Meeting Abstract July 2019

Differentiation of orbital lymphoproliferative diseases by metabolomics

Hiroyuki Shimizu; Hiroshi Goto; Yoshihiko Usui; Naoya Nezu; Kinya Tsubota; Marina Ogawa; Masaki Asakage

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3581.

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Application of Metagenomic Long-Read Sequencing for the Diagnosis of Herpetic Uveitis

An Approach to Predict Intraocular Diseases by Machine Learning Based on Vitreous Humor Immune Mediator Profile

MicroRNA Profiling in Extracellular Vesicles from Vitreous Humor and Serum of Patients with Ocular Sarcoidosis and Vitreoretinal Lymphoma

Clinical risk factors contributing to elongation of axial length in Vogt-Koyanagi-Harada disease

Association of Merkel cell polyomavirus and clinicopathological findings in primary eyelid Merkel cell carcinomas

Vitreous Humor Proteomic Profile in Patients With Vitreoretinal Lymphoma

Clinical factors related to low prevalence of Fuchs’ uveitis syndrome in Japan

Adalimumab Treatment for Recurrence of Ocular Inflammation in Patients with Vogt-Koyanagi-Harada Disease: a multicenter study

Differential Tissue Metabolic Signatures in IgG4-Related Ophthalmic Disease and Orbital Mucosa-Associated Lymphoid Tissue Lymphoma

Comprehensive miRNA Analysis Using Serum From Patients With Noninfectious Uveitis

Role of microglia in the formation of subretinal neovascularization in Vldlr -/ - mice

Evaluation of Retinal Pigment Epithelium Layer Change in Vogt-Koyanagi-Harada Disease With Multicontrast Optical Coherence Tomography

Cell population having a resistance to melanoma antigen specific T cell in uveal melanoma

Epidemiology of epiretinal membrane and macular edema in a large cohort of patients with uveitis

Association Between Axial Length and Uveitis

TRPM2 gene deficiency promotes the growth of laser-induced choroidal neovascularization in mice.

Comprehensive genetic analysis of IgG4-related ophthalmic diseases by RNA sequencing

Efficacy of infliximab and adalimumab for macular edema associated with uveitis

Outcome of vitrectomy for retinal hemangioma

Differentiation of orbital lymphoproliferative diseases by metabolomics

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