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Public Health March 2025

Visual Deficits in Type 2 Diabetes Mellitus Without Retinopathy: From Retinal Structure to Higher-Level Visual Functions

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Sha Luo; Lin Xia; Yue Wang; Yong Tang; Jiong Dong; Rong Liu; Lixia Feng
TAGS: diabetes mellitus, diabetes mellitus, type 2, retina, retinal diseases, vision, vision disorders
Trans. Vis. Sci. Tech.. 2025; 14(3):10. https://doi.org/10.1167/tvst.14.3.10

Includes: Supplemental Content

Retina March 2025

Characteristics of Retina, Choroid, and Retrobulbar Blood Flow in Myopes With Posterior Staphyloma Using Ultra-Widefield OCTA and CDI

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Fang Liu; Yunzhe Wang; Lingling Niu; Jing Zhao; Kang Xue; Xingtao Zhou
TAGS: choroid, retina, staphyloma, vascular flow, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):21. https://doi.org/10.1167/iovs.66.3.21

Genetics March 2025

Corneal Biomechanics Are Associated With FBN1 Mutations in Patients With Marfan Syndrome and Ectopia Lentis

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Qiu-Yi Huo; Rui-Zheng Zhang; Wan-Nan Jia; Ya-Lei Wang; Xin Shen; Xin-Yao Chen; Tian-Hui Chen; Yan Liu; Ling-Hao Song; Xinyue Wang; Yong Lv; Ze-Xu Chen; Yong-Xiang Jiang
TAGS: biomechanics, cornea, ectopia lentis, fibrillin-1, marfan syndrome, mutation, genotype
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):23. https://doi.org/10.1167/iovs.66.3.23

Includes: Supplemental Content

Cornea February 2025

Identification of Wnt-5a Receptors Important in Diabetic and Non-Diabetic Corneal Epithelial Wound Healing

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Ruchi Shah; Cynthia Amador; Adam J. Poe; Tanya M. Spektor; Priyanka Bhandary; Yizhou Wang; Zhiping Paul Wang; Daniel J. Weisenberger; Vanessa F. Borges; Onkar B. Sawant; Ezra Maguen; Pedram Hamrah; Andrei A. Kramerov; Mehrnoosh Saghizadeh; Alexander V. Ljubimov
TAGS: cornea, diabetes mellitus, receptors, wnt, wnt-5a protein, wound healing, epithelium, receptor tyrosine kinase-like orphan receptor 2
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):64. https://doi.org/10.1167/iovs.66.2.64

Includes: Supplemental Content

Clinical and Epidemiologic Research February 2025

Comprehensive Visualization of Choroidal Alterations in Thyroid Eye Disease With Ultra-Widefield OCT Angiography

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Yi Wang; Tengbo Rao; Jichao Zhou; Debo You; Jiarui Yang; Lingge Suo
TAGS: angiogram, eye, graves' ophthalmopathy, optic disk, cortical blindness, vascular flow, cardiovascular imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):25. https://doi.org/10.1167/iovs.66.2.25

Includes: Supplemental Content

Lens February 2025

Advanced Artificial-Intelligence-Based Jiang Formula for Intraocular Lens Power in Congenital Ectopia Lentis

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Yan Liu; Xinyue Wang; Linghao Song; Yang Sun; Zexu Chen; Wannan Jia; Xin Shen; Yalei Wang; Xinyao Chen; Qiuyi Huo; Pranav Prakash Edavi; Tianhui Chen; Yongxiang Jiang
TAGS: ectopia lentis, eye, intelligence, intraocular lens implant device, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2025; 14(2):5. https://doi.org/10.1167/tvst.14.2.5

Includes: Supplemental Content

Retina January 2025

ABCA4 Deep Intronic Variants Contributed to Nearly Half of Unsolved Stargardt Cases With a Milder Phenotype

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Yingwei Wang; Pangfeng Wang; Zhen Yi; Jiamin Ouyang; Yi Jiang; Shiqiang Li; Xiaoyun Jia; Xueshan Xiao; James Fielding Hejtmancik; Wenmin Sun; Qingjiong Zhang
TAGS: abca4 gene, introns, phenotype
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):65. https://doi.org/10.1167/iovs.66.1.65

Includes: Supplemental Content

Retina January 2025

Age- and Sex-Specific Regulation of Serine Racemase in the Retina of an Alzheimer's Disease Mouse

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Yan Wang; Dehuan Xu; Yuhang Zhao; Haiyu Zhu; Xiaoyu Xiu; Haiyan Jiang; Yimei Liu; Ge Shan; Shengzhou Wu
TAGS: mice, proteins, retina, serine, alzheimer's disease, regulation
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):36. https://doi.org/10.1167/iovs.66.1.36

Includes: Supplemental Content

Retinal Cell Biology January 2025

Retinal Müller Cell-Released Exosomal MiR-92a-3p Delivers Interleukin-17A Signal by Targeting Notch-1 to Promote Diabetic Retinopathy

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Ao-Wang Qiu; Ning-Yu Wang; Wen-Jie Yin; Zhao-Qi Zhu; Qing-Huai Liu; Wei-Wei Zhang
TAGS: cardiac support procedures, exosomes, interleukin-17, mast-cell sarcoma, millennium cohort study, minimally conscious state, diabetic retinopathy, interleukins, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):1. https://doi.org/10.1167/iovs.66.1.1

Glaucoma December 2024

A Pattern-Based OCT Metric for Glaucoma Detection

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Donald C. Hood; Sol La Bruna; Mary Durbin; Chris Lee; Anya Guzman; Tayna Gebhardt; Yujia Wang; Arin L. Stowman; Carlos Gustavo De Moraes; Michael Chaglasian; Emmanouil Tsamis
TAGS: eye, glaucoma, cohort studies
Trans. Vis. Sci. Tech.. 2024; 13(12):21. https://doi.org/10.1167/tvst.13.12.21

Includes: Supplemental Content

Retina December 2024

Early Diabetic Retinopathy Evaluation With OCTA: A Study on Vascular Branching and Fragmentation

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Yao Yu; Shiwei Cui; Yang He; Jiahao Zhang; Nan Lu; Yanqiu Yang; Jian Liu; Yi Wang; Zhenhe Ma
TAGS: diabetic retinopathy, human placental lactogen, embolic protection devices, diabetes mellitus, fovea centralis
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):21. https://doi.org/10.1167/iovs.65.14.21

Includes: Supplemental Content

Retina December 2024

Retinal Neurovascular Impairment in Full-Course Diabetic Retinopathy: The Guangdong Diabetic Retinopathy Multiple-Omics Study

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Chunran Lai; Ting Su; Jiahui Cao; Qinyi Li; Zijing Du; Yaxin Wang; Shan Wang; Qiaowei Wu; Yijun Hu; Ying Fang; Huiyi Liao; Zhuoting Zhu; Xianwen Shang; Mingguang He; Honghua Yu; Xiayin Zhang
TAGS: diabetes mellitus, type 2, diabetic retinopathy, electroretinography, nonproliferative diabetic retinopathy, peripheral neurovascular compromise, photopsia, retinal cone, optical coherence tomography, retina, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):20. https://doi.org/10.1167/iovs.65.14.20

Includes: Supplemental Content

Retina December 2024

Five-Year Incidence of Age-Related Macular Degeneration and Its Risk Factors in Adult Chinese Population: The Tongren Health Care Study

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Ying Cui; Jing Cui; Can Can Xue; Yu Mao; Jost B. Jonas; Ya Xing Wang; Dong Ning Chen
TAGS: adult, age-related macular degeneration, china, chinese people, health care, incidence, risk factors, diabetes mellitus
Trans. Vis. Sci. Tech.. 2024; 13(12):10. https://doi.org/10.1167/tvst.13.12.10

Includes: Supplemental Content

Cornea & External Disease November 2024

Efficacy of Terpinen-4-ol Combined With Eyelid Deep Cleaning for the Treatment of Demodex Blepharitis: A Randomized, Open-Label Trial

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Hao-Yu Wang; Dan Shen; Meng-Ying Qi; Chen Qiao; Lan Ke; Mingwu Wang; Qing-Yan Zeng
TAGS: blepharitis, eyelid, mites, ocular surfaces, eyelid margin, follow-up
Trans. Vis. Sci. Tech.. 2024; 13(11):22. https://doi.org/10.1167/tvst.13.11.22

Lens November 2024

In Utero/Childhood/ Adolescence Exposure to Tobacco Smoke and Elderly-Onset Cataract: A Large Prospective Cohort Study

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Chunran Lai; Yaxin Wang; Xiaomin Zeng; Zijing Du; Shan Wang; Zhanjie Lin; Yijun Hu; Ying Fang; Xiayin Zhang; Honghua Yu
TAGS: cataract, smoke, tobacco, adolescent, child, prospective studies, older adult
Trans. Vis. Sci. Tech.. 2024; 13(11):21. https://doi.org/10.1167/tvst.13.11.21

Includes: Supplemental Content

Genetics November 2024

Investigating Microperimetric Features in Bietti Crystalline Dystrophy Patients: A Cross-Sectional Longitudinal Study in a Large Cohort

PDF

Yufei Xu; Xiao Liu; Nan Wu; Yanling Long; Jiayun Ren; Yu Wang; Xinyi Su; Zengping Liu; Yu Fujinami-Yokokawa; Kaoru Fujinami; Fang Chen; Xiaohong Meng; Yong Liu
TAGS: cohort studies, crystal structure, disease progression, eye, fovea centralis, longitudinal studies, genotype, vision, blindness, mutation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):27. https://doi.org/10.1167/iovs.65.13.27

Includes: Supplemental Content

Retina November 2024

Choroidal Thickness and Visual Acuity in High Myopia Without Myopic Maculopathy: Insights From a Chinese Population Study

PDF

Yueye Wang; Decai Wang; Qiuxia Yin; Jiayong Li; Zhixi Li; Mingguang He
TAGS: macular disorders, myopia, population studies, vision, visual acuity, chinese (other dialects), chinese people
Trans. Vis. Sci. Tech.. 2024; 13(11):9. https://doi.org/10.1167/tvst.13.11.9

Includes: Supplemental Content

Retina October 2024

Automated Posterior Scleral Topography Assessment for Enhanced Staphyloma Visualization and Quantification With Improved Maculopathy Correlation

PDF

Ying Xiang Han; Xiao Xiao Guo; Ya Xing Wang; Jost B. Jonas; Xi Chen; Xiao Fei Wang
TAGS: sclera, staphyloma, macular disorders, eye, magnetic resonance imaging
Trans. Vis. Sci. Tech.. 2024; 13(10):41. https://doi.org/10.1167/tvst.13.10.41

Includes: Supplemental Content

Visual Neuroscience October 2024

The Short- and Long-Term Perceptual Learning of Clinical Dynamic Visual Acuity Test

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Xiaobing Wang; Mingxin Yan; Jingmin Li; Yuexin Wang
TAGS: learning, motion, perceptual learning, visual acuity testing
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):43. https://doi.org/10.1167/iovs.65.12.43

Review October 2024

Aberrant Lipid Metabolism and Complement Activation in Age-Related Macular Degeneration

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Siao Tang; Jiaqi Yang; Bingqing Xiao; Yani Wang; Yiou Lei; Dongwei Lai; Qinghua Qiu
TAGS: complement activation, complement system proteins, fat metabolism, lipoproteins, oxidized lipid, lipofuscin
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):20. https://doi.org/10.1167/iovs.65.12.20

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Visual Deficits in Type 2 Diabetes Mellitus Without Retinopathy: From Retinal Structure to Higher-Level Visual Functions

Characteristics of Retina, Choroid, and Retrobulbar Blood Flow in Myopes With Posterior Staphyloma Using Ultra-Widefield OCTA and CDI

Corneal Biomechanics Are Associated With FBN1 Mutations in Patients With Marfan Syndrome and Ectopia Lentis

Identification of Wnt-5a Receptors Important in Diabetic and Non-Diabetic Corneal Epithelial Wound Healing

Comprehensive Visualization of Choroidal Alterations in Thyroid Eye Disease With Ultra-Widefield OCT Angiography

Advanced Artificial-Intelligence-Based Jiang Formula for Intraocular Lens Power in Congenital Ectopia Lentis

ABCA4 Deep Intronic Variants Contributed to Nearly Half of Unsolved Stargardt Cases With a Milder Phenotype

Age- and Sex-Specific Regulation of Serine Racemase in the Retina of an Alzheimer's Disease Mouse

Retinal Müller Cell-Released Exosomal MiR-92a-3p Delivers Interleukin-17A Signal by Targeting Notch-1 to Promote Diabetic Retinopathy

A Pattern-Based OCT Metric for Glaucoma Detection

Early Diabetic Retinopathy Evaluation With OCTA: A Study on Vascular Branching and Fragmentation

Retinal Neurovascular Impairment in Full-Course Diabetic Retinopathy: The Guangdong Diabetic Retinopathy Multiple-Omics Study

Five-Year Incidence of Age-Related Macular Degeneration and Its Risk Factors in Adult Chinese Population: The Tongren Health Care Study

Efficacy of Terpinen-4-ol Combined With Eyelid Deep Cleaning for the Treatment of Demodex Blepharitis: A Randomized, Open-Label Trial

In Utero/Childhood/ Adolescence Exposure to Tobacco Smoke and Elderly-Onset Cataract: A Large Prospective Cohort Study

Investigating Microperimetric Features in Bietti Crystalline Dystrophy Patients: A Cross-Sectional Longitudinal Study in a Large Cohort

Choroidal Thickness and Visual Acuity in High Myopia Without Myopic Maculopathy: Insights From a Chinese Population Study

Automated Posterior Scleral Topography Assessment for Enhanced Staphyloma Visualization and Quantification With Improved Maculopathy Correlation

The Short- and Long-Term Perceptual Learning of Clinical Dynamic Visual Acuity Test

Aberrant Lipid Metabolism and Complement Activation in Age-Related Macular Degeneration

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