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Glaucoma June 2025

Cross-Tissue Transcriptome-Wide Association Study Identifies Novel Genes Associated With POAG

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Jianqi Chen; Xiaohua Zhuo; Yangjiani Li; Yingting Zhu; Zhidong Li; Xinyue Shen; Yehong Zhuo; Hongmei Tan; Lei Lei
TAGS: body tissue, genes, open-angle glaucoma
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):7. https://doi.org/10.1167/iovs.66.6.7

Includes: Supplemental Content

Glaucoma June 2025

Valproic Acid Application to Modify Post Surgical Fibrosis in a Model of Minimally Invasive Bleb Surgery

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Phey Feng Lo; Merry Gunawan; Zhu Li Yap; Carol Leong; Fuxuan Kwek; Jayasudha Varadarajan; Xiaomeng Wang; Masaaki Kageyama; Tina T. Wong
TAGS: blister, surgical procedures, operative, valproic acid, fibrosis, surgical procedures, minimally invasive, oryctolagus cuniculus
Trans. Vis. Sci. Tech.. 2025; 14(6):6. https://doi.org/10.1167/tvst.14.6.6

Includes: Supplemental Content

Refractive Intervention May 2025

Association Between Inflammatory Cytokines and Refractive Errors: A Bidirectional Mendelian Randomization Study

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Yue Xu; Xing-Xuan Dong; Yun Wang; Xin-Yu Zhuang; Ying-Jie Chen; Xiao-Feng Zhang; Chen-Wei Pan
TAGS: cytokine, mendelian randomization analysis, refractive errors, ciliary motility disorders
Trans. Vis. Sci. Tech.. 2025; 14(5):1. https://doi.org/10.1167/tvst.14.5.1

Includes: Supplemental Content

Glaucoma April 2025

Optic Nerve Morphology Influences Structure-Function Relationship in Early Glaucoma With and Without High Myopia

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Jinpeng Yang; Yangjiani Li; Qi Zhang; Simei Zeng; Haishun Huang; Caiqing Wu; Zhe Liu; Jiahui Tang; Siting Wu; Yuze Chen; Yehong Zhuo; Yangfan Yang; Yiqing Li
TAGS: glaucoma, language morphology, morphology, myopia, optic disk, optic nerve, eye
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):18. https://doi.org/10.1167/iovs.66.4.18

Includes: Supplemental Content

Retina February 2025

Association Between Hormone Levels and Retinopathy in Patients With Type 2 Diabetes: A Cross-Sectional Study

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Yu Meng; Xueli Yang; Yuxin Fan; Ming Liu; Fengqi Zhou; Qihua Wang; Yuezhu Lu; Yun Zhu; Hua Yan
TAGS: diabetes mellitus, type 2, gonadal hormones, hormones, retinal diseases, testosterone
Trans. Vis. Sci. Tech.. 2025; 14(2):17. https://doi.org/10.1167/tvst.14.2.17

Includes: Supplemental Content

Public Health February 2025

Associations Between Diabetic Retinopathy and Frailty: Insights From the National Health and Nutrition Examination Survey and Mendelian Randomization

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Jianqi Chen; Xuhao Chen; Xu Cao; Xiaohua Zhuo; Yuwen Wen; Guitong Ye; Yuan Zhang; Jinan Zhan; Hongmei Tan; Yingting Zhu; Yehong Zhuo
TAGS: frailty, national health and nutrition examination survey, diabetic retinopathy, mendelian randomization analysis
Trans. Vis. Sci. Tech.. 2025; 14(2):2. https://doi.org/10.1167/tvst.14.2.2

Includes: Supplemental Content

Glaucoma November 2024

The Mechanisms of Neuroprotection by Topical Rho Kinase Inhibition in Experimental Mouse Glaucoma and Optic Neuropathy

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Sarah E. Quillen; Elizabeth C. Kimball; Kelsey A. Ritter-Gordy; Liya Du; Zhuochen Yuan; Mary E. Pease; Salaheddine Madhoun; Thao D. Nguyen; Thomas V. Johnson; Harry A. Quigley; Ian F. Pitha
TAGS: astrocytes, did not receive therapy or drug, eye, glaucoma, mice, neuroprotection, optic nerve disorders, phosphotransferases, proteins, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):43. https://doi.org/10.1167/iovs.65.13.43

Includes: Supplemental Content

Glaucoma October 2024

Normative Profile of Retinal Nerve Fiber Layer Thickness and Lamina Cribrosa-Related Parameters in a Healthy Non-Glaucoma Cynomolgus Monkey Colony

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Jian Wu; Ruyue Li; Sirui Zhu; Kezhe Chen; Caixia Lin; Jiaxin Tian; Lijie Pan; Hongyi Liu; Xu Jia; Ziyu Yu; Zhidong Li; Yingting Zhu; Wei Liu; Chenlong Yang; Chiwai Wong; Ningli Wang; Yehong Zhuo; for the Non-Human Primate Eye Study Group
TAGS: glaucoma, macaca fascicularis, retinal nerve fiber layer, eye, cercopithecidae, intraocular pressure
Trans. Vis. Sci. Tech.. 2024; 13(10):6. https://doi.org/10.1167/tvst.13.10.6

Includes: Supplemental Content

Cornea October 2024

Mesenchymal Stem Cells-Derived Exosomal miR-223-3p Alleviates Ocular Surface Damage and Inflammation by Downregulating Fbxw7 in Dry Eye Models

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Guifang Wang; Yujie Zhu; Yuzhen Liu; Mulin Yang; Li Zeng
TAGS: bacterial artificial chromosomes, blood alcohol concentration, bronchioloalveolar carcinoma, dry eye syndromes, f-box-wd repeat-containing protein 7, fbxw7 gene, inflammation, mice, ocular surfaces, cornea
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):1. https://doi.org/10.1167/iovs.65.12.1

Includes: Supplemental Content

Retina September 2024

Peripapillary Retinal Nerve Fiber Layer and Macular Ganglion Cell-Inner Plexiform Layer Parameters and Their Associated Factors in Cynomolgus Macaques

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Yuan Zhang; Guitong Ye; Kezhe Chen; Shaofen Huang; Rui Xie; Jianqi Chen; Wei Liu; Zhiwei Wang; Ruiyu Luo; Jinan Zhan; Yehong Zhuo; Yiqing Li; Yingting Zhu
TAGS: ganglia, macaca fascicularis, retinal nerve fiber layer, cercopithecidae, nose
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):14. https://doi.org/10.1167/iovs.65.11.14

Includes: Supplemental Content

Lens September 2024

Lens Power and Associated Factors in Nonhuman Primate Subjects: A Cross-sectional Study

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Yingting Zhu; Rui Xie; Qi Zhang; Yuan Zhang; Guitong Ye; Liangzhi Xu; Simeng Hou; Wei Liu; Zhiwei Huang; Jian Wu; Yehong Zhuo
TAGS: cross-sectional studies, eye, lens, crystalline, primates, myopia
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):2. https://doi.org/10.1167/iovs.65.11.2

Includes: Supplemental Content

Retina July 2024

Longitudinal Assessment of Intraretinal Microvascular Abnormalities in Diabetic Retinopathy Using Swept-Source Optical Coherence Tomography Angiography

PDF

Xinyi Ding; Francesco Romano; Itika Garg; Jenny Gan; Katherine M. Overbey; Mauricio D. Garcia; Filippos Vingopoulos; Ying Cui; Ying Zhu; Grace Baldwin; Hanna Choi; Jocelyn M. Rodriguez; Matthew J. Finn; Peyman Razavi; Demetrios G. Vavvas; Deeba Husain; David M. Wu; Nimesh A. Patel; Leo A. Kim; Joan W. Miller; John B. Miller
TAGS: angiogram, diabetic retinopathy, immunoradiometric assays, optical coherence tomography, follow-up
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):29. https://doi.org/10.1167/iovs.65.8.29

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Comparison of Traction Forces in Ex-situ Vitrectomy Using 25-Ga 20000 CPM Dual Blade Vitrectomy Probes and 25-Ga 10000 CPM Single Blade Vitrectomy Probes

Brian McDonell; Ying Zhu; Kevin Phan; Vara Wuyyuru; Steve Charles

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):902.

ARVO Annual Meeting Abstract June 2024

Impact of parental myopia on myopia control efficacy of spectacle lenses with cylindrical annular refractive elements (CARE)

Christina Boeck-Maier; Padmaja Sankaridurg; Arne Ohlendorf; Katharina Rifai; Siegfried Wahl; Xiaoqin Chen; Cui Yu; Min Wu; Yi Zhu; Youhua Yang; Lihua Li

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):146.

ARVO Annual Meeting Abstract June 2024

Subjective acceptance of spectacle lenses with cylindrical annular refractive elements (CARE) in Chinese children with myopia

Katharina Rifai; Padmaja Sankaridurg; Arne Ohlendorf; Christina Boeck-Maier; Youhua Yang; Yi Zhu; Xiaoqin Chen; Min Wu; Cui Yu; Siegfried Wahl; Lihua Li

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):145.

ARVO Annual Meeting Abstract June 2024

Probability of surviving fast progression and eye growth reversal after 1-year of spectacle wear with cylindrical annular refractive elements

Padmaja Sankaridurg; Xiaoqin Chen; Katharina Rifai; Min Wu; Cui Yu; Arne Ohlendorf; Christina Boeck-Maier; Siegfried Wahl; Youhua Yang; Yi Zhu; Lihua Li

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):144.

ARVO Annual Meeting Abstract June 2024

Discovery and Analysis of Müller Cell-Originated Slow Spontaneous Voltage Fluctuations

Yan Zhu; Patrick Hunt; Benjamin J Frankfort; Zheng Jiang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2779.

ARVO Annual Meeting Abstract June 2024

Development of a Comprehensive Predictive Model for Primary Open-Angle Glaucoma in Individuals of African Ancestry

Shefali Setia Verma; Lannawill Caruth; Yuki Bradford; Yan Zhu; Rebecca Salowe; Tyler Kinzy; Chiea Chuen Khor; Michael A Hauser; Jessica Cooke Bailey; Marylyn D Ritchie; Joan M O'Brien

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2762.

ARVO Annual Meeting Abstract June 2024

Slowing myopia progression with cylindrical annular refractive elements (CARE) – 12-month interim results from a 2-year prospective multi-center trial

Xiaoqin Chen; Min Wu; Cui Yu; Arne Ohlendorf; Sankaridurg Padmaja; Katharina Rifai; Christina Boeck-Maier; Siegfried Wahl; Youhua Yang; Yi Zhu; Lihua Li

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2736.

ARVO Annual Meeting Abstract June 2024

PKG inhibition reduces rod and cone photoreceptor cell death in the new Rho I255del mouse model for autosomal dominant retinitis pigmentosa.

yu zhu; francois paquet-durand

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4742.

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Cross-Tissue Transcriptome-Wide Association Study Identifies Novel Genes Associated With POAG

Valproic Acid Application to Modify Post Surgical Fibrosis in a Model of Minimally Invasive Bleb Surgery

Association Between Inflammatory Cytokines and Refractive Errors: A Bidirectional Mendelian Randomization Study

Optic Nerve Morphology Influences Structure-Function Relationship in Early Glaucoma With and Without High Myopia

Association Between Hormone Levels and Retinopathy in Patients With Type 2 Diabetes: A Cross-Sectional Study

Associations Between Diabetic Retinopathy and Frailty: Insights From the National Health and Nutrition Examination Survey and Mendelian Randomization

The Mechanisms of Neuroprotection by Topical Rho Kinase Inhibition in Experimental Mouse Glaucoma and Optic Neuropathy

Normative Profile of Retinal Nerve Fiber Layer Thickness and Lamina Cribrosa-Related Parameters in a Healthy Non-Glaucoma Cynomolgus Monkey Colony

Mesenchymal Stem Cells-Derived Exosomal miR-223-3p Alleviates Ocular Surface Damage and Inflammation by Downregulating Fbxw7 in Dry Eye Models

Peripapillary Retinal Nerve Fiber Layer and Macular Ganglion Cell-Inner Plexiform Layer Parameters and Their Associated Factors in Cynomolgus Macaques

Lens Power and Associated Factors in Nonhuman Primate Subjects: A Cross-sectional Study

Longitudinal Assessment of Intraretinal Microvascular Abnormalities in Diabetic Retinopathy Using Swept-Source Optical Coherence Tomography Angiography

Comparison of Traction Forces in Ex-situ Vitrectomy Using 25-Ga 20000 CPM Dual Blade Vitrectomy Probes and 25-Ga 10000 CPM Single Blade Vitrectomy Probes

Impact of parental myopia on myopia control efficacy of spectacle lenses with cylindrical annular refractive elements (CARE)

Subjective acceptance of spectacle lenses with cylindrical annular refractive elements (CARE) in Chinese children with myopia

Probability of surviving fast progression and eye growth reversal after 1-year of spectacle wear with cylindrical annular refractive elements

Discovery and Analysis of Müller Cell-Originated Slow Spontaneous Voltage Fluctuations

Development of a Comprehensive Predictive Model for Primary Open-Angle Glaucoma in Individuals of African Ancestry

Slowing myopia progression with cylindrical annular refractive elements (CARE) – 12-month interim results from a 2-year prospective multi-center trial

PKG inhibition reduces rod and cone photoreceptor cell death in the new Rho I255del mouse model for autosomal dominant retinitis pigmentosa.

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