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Journal Articles (5)
Meeting Abstract (4)

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Investigative Ophthalmology & Visual Science (9)

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ARVO Annual Meeting Abstract (4)
Biochemistry and Molecular Biology (2)
Perspective (1)
Retinal Cell Biology (1)
Review (1)

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Biochemistry and Molecular Biology (3)
Eye Anatomy and Disorders (3)
Retina (3)
Genetics (2)
Imaging (2)
Retinal Imaging (2)
Multidisciplinary Ophthalmic Imaging (1)
Retinal Cell Biology (1)

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lipofuscin (3)
retinal pigment epithelium (2)
apoptosis (1)
autofluorescence (1)
caspase-1 (1)
cattle (1)
cell death (1)
dimers (1)
energy absorbance (1)
epithelium (1)

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ARVO Annual Meeting Abstract July 2019

NLRP3 inflammasome activation by all- trans -retinaldehyde underlies the degeneration of retinal pigment epithelial cells

Yi Liao; Yalin Wu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1929.

Retinal Cell Biology July 2019

Retinal Pigment Epithelium Cell Death Is Associated With NLRP3 Inflammasome Activation by All- trans Retinal

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Yi Liao; Houjian Zhang; Danxue He; Yan Wang; Binxiang Cai; Jingmeng Chen; Jianxing Ma; Zuguo Liu; Yalin Wu
TAGS: caspase-1, inflammasomes, nlr family, pyrin domain-containing 3 protein, retinal pigment epithelium, cell death, interleukin-18
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3034-3045. https://doi.org/10.1167/iovs.18-26360

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

All- trans -retinaldehyde participates in complement activation in retinal pigment epithelium by downregulating complement regulatory proteins

Yi Liao; Yalin Wu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3990.

ARVO Annual Meeting Abstract July 2018

The Visual Chromophore All- Trans -Retinaldehyde in Retinal Pigment Epithelial Cells: An Alternative Metabolic Pathway

Yalin Wu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4037.

Biochemistry and Molecular Biology February 2017

Aberrant Buildup of All- Trans -Retinal Dimer, a Nonpyridinium Bisretinoid Lipofuscin Fluorophore, Contributes to the Degeneration of the Retinal Pigment Epithelium

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Junli Zhao; Yi Liao; Jingmeng Chen; Xinran Dong; Zhan Gao; Houjian Zhang; Xiaodan Wu; Zuguo Liu; Yalin Wu
TAGS: dimers, lipofuscin, tissue degeneration, retinal pigment cell, apoptosis, retinal pigment epithelium, mice
Invest. Ophthalmol. Vis. Sci.. 2017; 58(2):1063-1075. https://doi.org/10.1167/iovs.16-20734

Includes: Supplemental Content

Review March 2016

Potential Therapeutic Agents Against Retinal Diseases Caused by Aberrant Metabolism of Retinoids

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Xin Liu; Jingmeng Chen; Zhe Liu; Jie Li; Ke Yao; Yalin Wu
TAGS: metabolism, retinal diseases, retinoids
Invest. Ophthalmol. Vis. Sci.. 2016; 57(3):1017-1030. https://doi.org/10.1167/iovs.15-18429

ARVO Annual Meeting Abstract June 2015

Autophagy inhibitor attenuated A2E induced inflammatory factors in ARPE-19 cells: implications for age-related macular degeneration

Yujing Bai; Jingjing Zhang; Yalin Wu; Xiaoxin Li

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2393.

Biochemistry and Molecular Biology December 2014

Preparative and Biosynthetic Insights Into pdA2E and iso pdA2E, Retinal-Derived Fluorophores of Retinal Pigment Epithelial Lipofuscin

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Junli Zhao; Ke Yao; Qiuxia Jin; Kezhi Jiang; Jingmeng Chen; Zhe Liu; Jie Li; Yalin Wu
TAGS: international organization for standardization, lipofuscin, pigment, epithelium, high pressure liquid chromatography procedure, energy absorbance, eye, cattle
Invest. Ophthalmol. Vis. Sci.. 2014; 55(12):8241-8250. https://doi.org/10.1167/iovs.14-15709

Includes: Supplemental Content

Perspective September 2010

Interpretations of Fundus Autofluorescence from Studies of the Bisretinoids of the Retina

PDF

Janet R. Sparrow; Kee Dong Yoon; Yalin Wu; Kazunori Yamamoto
TAGS: fundus autofluorescence imaging, lipofuscin, retina, autofluorescence, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2010; 51(9):4351-4357. https://doi.org/10.1167/iovs.10-5852

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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