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Articles January 2019

Gray Matter Volume Changes in Patients With Acute Eye Pain: A Voxel-Based Morphometry Study

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Dong-Yi Lan; Pei-Wen Zhu; Ying He; Qian-Hui Xu; Ting Su; Biao Li; Wen-Qing Shi; Qi Lin; Yan-Chang Yang; Qing Yuan; Jian-Wen Fang; Qing-Hai Li; Yi Shao
TAGS: limbic lobe, ocular pain, brain, roc curve, human placental lactogen, local area networks, voxel, insula of reil, gray matter, volume
Trans. Vis. Sci. Tech.. 2019; 8(1):1. doi: 10.1167/tvst.8.1.1

Biochemistry and Molecular Biology December 2018

Opposing Effects of PPARα Agonism and Antagonism on Refractive Development and Form Deprivation Myopia in Guinea Pigs

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Miaozhen Pan; Shiming Jiao; Peter S. Reinach; Jiaofeng Yan; Yanan Yang; Qihang Li; Nethrajeith Srinivasalu; Jia Qu; Xiangtian Zhou
TAGS: bezafibrate, caviidae, injections, myopia, apolipoprotein a-ii, eye, ppar alpha
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5803-5815. doi: 10.1167/iovs.17-22297

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

A negative regulator of neurite growth – Insulin-like growth factor binding protein 7

Yingqian Li; Kin-Sang Cho; Yanhui Yang; Hetian Lei; Dong Feng Chen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1861. doi:

ARVO Annual Meeting Abstract July 2018

The Sirtuin Inhibitor Tenovin-6 as a Novel Regulator of the TP53-MDM2 Signaling Pathway in Uveal Melanoma

Matthew W Wilson; Matthew W McEwen; Zachary K. Goldsmith; Kelley Yuan; Andrew Irvine; Benjamin King; Hua Yang Yang; Hans Grossniklaus; Vanessa Marie Morales-Tirado

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3175. doi:

ARVO Annual Meeting Abstract July 2018

The Impact of Short-term Play of Visual Reality Games on Ocular Surface, Tear Functions and Dioptric Status in College Students.

Zongyi Zhan; Yangfan Yang; Minbin Yu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4867. doi:

Biochemistry and Molecular Biology May 2018

Dopamine D1 Receptors Contribute Critically to the Apomorphine-Induced Inhibition of Form-Deprivation Myopia in Mice

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Furong Huang; Lishuai Zhang; Qiongsi Wang; Yanan Yang; Qihang Li; Yi Wu; Jiangfan Chen; Jia Qu; Xiangtian Zhou
TAGS: apomorphine, myopia, dopamine d1 receptor, mice
Invest. Ophthalmol. Vis. Sci.. 2018; 59(6):2623-2634. doi: 10.1167/iovs.17-22578

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Attenuation of myopia progression by aripiprazole is dependent on form deprivation

Furong Huang; Fen Wan; Yanan Yang; Jia Qu; Xiangtian Zhou

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5468. doi:

Visual Neuroscience November 2016

Electrically Evoked Responses in the Rabbit Cortex Induced by Current Steering With Penetrating Optic Nerve Electrodes

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Yan Yan; Yiliang Lu; Menghui Li; Zengguang Ma; Pengjia Cao; Yao Chen; Xiaodong Sun; Xinyu Chai; Qiushi Ren; Liming Li
TAGS: oryctolagus cuniculus, optic nerve
Invest. Ophthalmol. Vis. Sci.. 2016; 57(14):6327-6338. doi: 10.1167/iovs.15-17543

Glaucoma September 2016

Tetramethylpyrazine Attenuates Transdifferentiation of TGF-β2–Treated Human Tenon's Fibroblasts

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Xiaoxiao Cai; Yangfan Yang; Pei Chen; Yiming Ye; Xiao'an Liu; Kaili Wu; Minbin Yu
TAGS: actins, western blotting, fibroblasts, fibrosis, fluorescent antibody technique, tenon's capsule, attenuation, cell transdifferentiation
Invest. Ophthalmol. Vis. Sci.. 2016; 57(11):4740-4748. doi: 10.1167/iovs.16-19529

Glaucoma February 2016

Down-regulation of 14-3-3 Zeta Inhibits TGF-β1–Induced Actomyosin Contraction in Human Trabecular Meshwork Cells Through RhoA Signaling Pathway

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Yiming Ye; Yangfan Yang; Xiaoxiao Cai; Liling Liu; Kaili Wu; Minbin Yu
TAGS: actomyosin, cytoskeleton, down-regulation, phosphorylation, rhoa gtp-binding protein, trabecular meshwork, signal pathway, signal transduction pathways, rna, small interfering
Invest. Ophthalmol. Vis. Sci.. 2016; 57(2):719-730. doi: 10.1167/iovs.15-17438

ARVO Annual Meeting Abstract June 2015

Pharmacokinetics of Intravitreal Sirolimus in Non-infectious Uveitis (NIU) of the Posterior Segment: Results from a Subset of SAKURA Study 1 Subjects

Daniel Rosberger; Yang Yang; Masaaki Kageyama; Hidetoshi Mano; Hitomi Takenaga; Kenji Ueda; Lisa Lawrence-Miyasaki; SAKURA Study 1

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3114. doi:

ARVO Annual Meeting Abstract June 2015

Long-Term Safety of Intravitreal Sirolimus for the Treatment of Non-infectious Uveitis (NIU) of the Posterior Segment: 12-Month Results from SAKURA Study 1

Pauline T Merrill; Yang Yang

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5776. doi:

Visual Neuroscience August 2014

Optical Imaging of Visual Cortical Responses Evoked by Transcorneal Electrical Stimulation With Different Parameters

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Zengguang Ma; Pengjia Cao; Pengcheng Sun; Liming Li; Yiliang Lu; Yan Yan; Yao Chen; Xinyu Chai
TAGS: electric stimulation, optics, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2014; 55(8):5320-5331. doi: 10.1167/iovs.14-14600

ARVO Annual Meeting Abstract April 2014

Evaluation of Pirfenidone as a Postoperative Anti-proliferative Agent in Experimental Cataract Surgery: A Pilot Study

Yangfan Yang; Xianchai Lin; Kaili Wu; Minbin Yu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6308. doi:

ARVO Annual Meeting Abstract April 2014

The SAKURA Study, a Phase III, Multicenter, Randomized, Double-Masked, Study of Intravitreal Injections of DE-109 for the Treatment of Active, Noninfectious Uveitis of the Posterior Segment: Baseline Ocular Disease Characteristics

Pauline Merrill; Quan Dong Nguyen; W Lloyd Clark; Laura Wilson; Marye Ellen Valentine; Joel Naor; Naveed Shams; Afsheen Khwaja; Yang Yang; SAKURA Study Group

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):109. doi:

Immunology and Microbiology April 2014

Activation of Liver X Receptor Alleviates Ocular Inflammation in Experimental Autoimmune Uveitis

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Hongxia Yang; Shijie Zheng; Yiguo Qiu; Yan Yang; Chaokui Wang; Peizeng Yang; Qiuhong Li; Bo Lei
TAGS: cytokine, autoimmune diseases, autoimmunity, interleukin-17, lymphocyte, peptides, uveitis, mice, retina, prevention, liver x receptors, eye inflammation
Invest. Ophthalmol. Vis. Sci.. 2014; 55(4):2795-2804. doi: 10.1167/iovs.13-13323

Cornea October 2013

Morphologic Characteristics and Proliferation of Rabbit Corneal Stromal Cells Onto Complexes of Collagen–Chitosan–Sodium Hyaluronate Under Simulated Microgravity

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Xiaoxia Li; Yan Yang; Qinhua Li; Ying Dai; Chan Wang; Jiansu Chen
TAGS: collagen, oryctolagus cuniculus, stromal cells, cornea, sodium, microgravity, keratocytes, chitosan, complex
Invest. Ophthalmol. Vis. Sci.. 2013; 54(10):6877-6885. doi: 10.1167/iovs.13-12709

ARVO Annual Meeting Abstract June 2013

Regional variations in corneal and scleral mRNA expressions of MMP2, TIMP2, TGFβ2 in highly myopic-astigmatic chicks

Chea-Su Kee; Yan-yan Xi; Chin-Hung Geoffrey Chu; Shea Ping Yip; Jody Summers Rada

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3676. doi:

ARVO Annual Meeting Abstract June 2013

Simulating current focusing and steering in penetrative optic nerve stimulation: a computational model

Qiushi Ren; Menghui Li; Yan Yan; Liming Li

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1041. doi:

ARVO Annual Meeting Abstract June 2013

Spatial resolution of the Penetrative Optic Nerve Visual Prosthesis estimated by epidural cortical recording

Yao Chen; Yiliang Lu; Yan Yan; Liming Li; Xinyu Chai

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1060. doi:

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Gray Matter Volume Changes in Patients With Acute Eye Pain: A Voxel-Based Morphometry Study

Opposing Effects of PPARα Agonism and Antagonism on Refractive Development and Form Deprivation Myopia in Guinea Pigs

A negative regulator of neurite growth – Insulin-like growth factor binding protein 7

The Sirtuin Inhibitor Tenovin-6 as a Novel Regulator of the TP53-MDM2 Signaling Pathway in Uveal Melanoma

The Impact of Short-term Play of Visual Reality Games on Ocular Surface, Tear Functions and Dioptric Status in College Students.

Dopamine D1 Receptors Contribute Critically to the Apomorphine-Induced Inhibition of Form-Deprivation Myopia in Mice

Attenuation of myopia progression by aripiprazole is dependent on form deprivation

Electrically Evoked Responses in the Rabbit Cortex Induced by Current Steering With Penetrating Optic Nerve Electrodes

Tetramethylpyrazine Attenuates Transdifferentiation of TGF-β2–Treated Human Tenon's Fibroblasts

Down-regulation of 14-3-3 Zeta Inhibits TGF-β1–Induced Actomyosin Contraction in Human Trabecular Meshwork Cells Through RhoA Signaling Pathway

Pharmacokinetics of Intravitreal Sirolimus in Non-infectious Uveitis (NIU) of the Posterior Segment: Results from a Subset of SAKURA Study 1 Subjects

Long-Term Safety of Intravitreal Sirolimus for the Treatment of Non-infectious Uveitis (NIU) of the Posterior Segment: 12-Month Results from SAKURA Study 1

Optical Imaging of Visual Cortical Responses Evoked by Transcorneal Electrical Stimulation With Different Parameters

Evaluation of Pirfenidone as a Postoperative Anti-proliferative Agent in Experimental Cataract Surgery: A Pilot Study

The SAKURA Study, a Phase III, Multicenter, Randomized, Double-Masked, Study of Intravitreal Injections of DE-109 for the Treatment of Active, Noninfectious Uveitis of the Posterior Segment: Baseline Ocular Disease Characteristics

Activation of Liver X Receptor Alleviates Ocular Inflammation in Experimental Autoimmune Uveitis

Morphologic Characteristics and Proliferation of Rabbit Corneal Stromal Cells Onto Complexes of Collagen–Chitosan–Sodium Hyaluronate Under Simulated Microgravity

Regional variations in corneal and scleral mRNA expressions of MMP2, TIMP2, TGFβ2 in highly myopic-astigmatic chicks

Simulating current focusing and steering in penetrative optic nerve stimulation: a computational model

Spatial resolution of the Penetrative Optic Nerve Visual Prosthesis estimated by epidural cortical recording

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