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Glaucoma October 2020

Lamina Cribrosa Capillaries Straighten as Intraocular Pressure Increases

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Bryn L. Brazile; Bin Yang; Susannah Waxman; Po Lam; Andrew P. Voorhees; Yi Hua; Ralitsa T. Loewen; Nils A. Loewen; Joseph F. Rizzo, III; Tatjana Jakobs; Ian A. Sigal
TAGS: blood capillaries, cribriform plate, intraocular pressure, vasculature, eye
Invest. Ophthalmol. Vis. Sci.. 2020; 61(12):2. doi: https://doi.org/10.1167/iovs.61.12.2

Visual Neuroscience August 2020

Reduced Dendritic Spines in the Visual Cortex Contralateral to the Optic Nerve Crush Eye in Adult Mice

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Zongyi Zhan; Yali Wu; Zitian Liu; Yadan Quan; Deling Li; Yiru Huang; Shana Yang; Kaili Wu; Lianyan Huang; Minbin Yu
TAGS: adult, dendritic spines, eye, mice, optic nerve, primary visual cortex, visual cortex, neurotrophic tyrosine kinase receptor type 2, proteins
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):55. doi: https://doi.org/10.1167/iovs.61.10.55

Includes: Supplemental Content

Physiology and Pharmacology July 2020

Development of Animal Models for Lens and Corneal Diseases Using N-Methyl-N-Nitrosourea

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Yingxin Qu; Runpu Li; Xiaoqi Li; Qinghua Yang; Jianwen Chen; Yan Dong; Wentian Xiao; Shuo Zheng; Liqiang Wang; Ye Tao; Yifei Huang
TAGS: animal model, apoptosis, lens (device), lens, crystalline, cornea, methylnitrosourea, corneal diseases, rats, cataract
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):38. doi: https://doi.org/10.1167/iovs.61.8.38

Special Issue July 2020

Leveraging Multimodal Deep Learning Architecture with Retina Lesion Information to Detect Diabetic Retinopathy

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Vincent S. Tseng; Ching-Long Chen; Chang-Min Liang; Ming-Cheng Tai; Jung-Tzu Liu; Po-Yi Wu; Ming-Shan Deng; Ya-Wen Lee; Teng-Yi Huang; Yi-Hao Chen
TAGS: deep learning, diabetic retinopathy, retina, ophthalmologists
Trans. Vis. Sci. Tech.. 2020; 9(2):41. doi: https://doi.org/10.1167/tvst.9.2.41

ARVO Annual Meeting Abstract June 2020

Factors influencing oxygen concentration in the lamina cribrosa

Jason Arthur Walker; Yi Hua; Haiden McDonald; Pedro Pallares; Bryn Brazile; Ian A. Sigal

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):632. doi:

ARVO Annual Meeting Abstract June 2020

Local decreases in lamina cribrosa oxygen concentration under elevated IOP are not correlated with the degree of IOP-induced compression

Yi Hua; Haiden McDonald; Jason Walker; Pedro Pallares; Bryn Brazile; Ian A. Sigal

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3532. doi:

ARVO Annual Meeting Abstract June 2020

Characterization of lamina cribrosa beam insertion into the sclera canal in sheep, pig, monkey, and human

Fengting Ji; Bin Yang; Yi Hua; Po-Yi Lee; Ziyi Zhu; Ian A Sigal

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4782. doi:

ARVO Annual Meeting Abstract June 2020

Microstructural evidence that lamina cribrosa beams (LC), peripapillary sclera (PPS) and central retinal artery (CRA) have distinct mechanical behaviors when stretched

Po-Yi Lee; Bin Yang; Ziyi Zhu; Fengting Ji; Yi Hua; Ian A. Sigal

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4783. doi:

ARVO Annual Meeting Abstract June 2020

Adaptation and visual comfort in children with new spectacle lenses containing concentric rings of contiguous aspherical micro-lenses for myopia control

Bjorn Drobe; Adeline Yang; Yingying Huang; Jiawen Huo; Ee Woon Lim; XUE LI; Yiguo Pan; Jinhua Bao; Daniel P Spiegel; Hao Chen

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):94. doi:

ARVO Annual Meeting Abstract June 2020

Comparison of multi-retinal layer segmentation vs. existing segmentation in CIRRUS OCT images

Jan Marco Kost; Homayoun Bagherinia; Katherine Makedonsky; Yijun Huang; Jason Anderson; Roger A. Goldberg; Mary K Durbin; Ali Fard

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4575. doi:

Cornea May 2020

Agrin Promotes Limbal Stem Cell Proliferation and Corneal Wound Healing Through Hippo-Yap Signaling Pathway

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Lulu Hou; Wenbin Fu; Ying Liu; Qun Wang; Liqiang Wang; Yifei Huang
TAGS: agrin, cornea, stem cells, wound healing, signal pathway, signal transduction pathways
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):7. doi: https://doi.org/10.1167/iovs.61.5.7

ARVO Imaging in the Eye Conference Abstract August 2019

Real-time measurement of lamina cribrosa and sclera collagen architecture and mechanics at sub-micron resolution

Ian A Sigal; PoYi Lee; Bryn Brazile; Po Lam; Ziyi Zhu; Yi Hua; Bin Yang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(11):011. doi:

ARVO Imaging in the Eye Conference Abstract August 2019

Drusen Dynamics using Optical Coherence Tomography (OCT)

Jeong W Pak; Amitha Domalpally; Yijun Huang; Dawn Myers; Barbara Blodi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(11):PB0123. doi:

ARVO Annual Meeting Abstract July 2019

Collagen fiber interweaving strongly influences sclera stiffness, and likely plays a central role in globe mechanics

Ian A Sigal; Bingrui Wang; Bin Yang; Po-Yi Lee; Tian Yong Foong; Bryn Brazile; Yi Hua

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6177. doi:

ARVO Annual Meeting Abstract July 2019

OCT in Neonate Monkeys With and Without Maternal Zika Virus Exposure

Carol A Rasmussen; Seth Eaton; Nathan Diers; Peter Cueno; Emma L Mohr; David H O’Connor; Alexander W Katz; Michelle Schotzko; Christopher J Murphy; Yijun Huang; T Michael Nork

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):201. doi:

ARVO Annual Meeting Abstract July 2019

CNV lesion OCT segmentation in a clinical trial of wet AMD

Ronald P Danis; Yijun Huang; Courtney Konieczko; Jason Anderson; lydia garlie; David Bingaman; Kristine Curtiss; Paul Chaney; Martin Wax

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1209. doi:

ARVO Annual Meeting Abstract July 2019

Performance of a Novel OCT Segmentation Method for Determining Lesion Volume in the Assessment of a Non-Human Primate Model of Choroidal Neovascularization

Seth Eaton; Yijun Huang; Ronald P Danis; T. Michael Nork; Carol Rasmussen; Hugh Wabers; Michael Neider; Brian J Christian; Menno Van Lookeren Campagne; Christopher J Murphy

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1253. doi:

ARVO Annual Meeting Abstract July 2019

The Effect of Different Optical Corrections on Accommodation of Myopic Children

Jinhua Bao; Yunyun Chen; Chenglu Ding; Yingying Huang; Björn Drobe; Hao Chen

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1792. doi:

ARVO Annual Meeting Abstract July 2019

Performance evaluation of multi-retinal layer segmentation using SD-OCT

Ting Luo; Homayoun Bagherinia; Ali Fard; Jason Anderson; Yijun Huang; Katherine Makedonsky; Mary K Durbin

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):169. doi:

Immunology and Microbiology March 2019

Impaired Autophagic Degradation of Transforming Growth Factor-β-Induced Protein by Macrophages in Lattice Corneal Dystrophy

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Ji Han; Ming Zhang; Hai-Yan Lin; Feng-Ying Huang; Ying-Ying Lin; Guang-Hong Tan; Zhen-You Zheng
TAGS: autophagy, catabolism, hereditary corneal dystrophy, macrophages, proteins
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):978-989. doi: https://doi.org/10.1167/iovs.18-25838

Includes: Supplemental Content

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Lamina Cribrosa Capillaries Straighten as Intraocular Pressure Increases

Reduced Dendritic Spines in the Visual Cortex Contralateral to the Optic Nerve Crush Eye in Adult Mice

Development of Animal Models for Lens and Corneal Diseases Using N-Methyl-N-Nitrosourea

Leveraging Multimodal Deep Learning Architecture with Retina Lesion Information to Detect Diabetic Retinopathy

Factors influencing oxygen concentration in the lamina cribrosa

Local decreases in lamina cribrosa oxygen concentration under elevated IOP are not correlated with the degree of IOP-induced compression

Characterization of lamina cribrosa beam insertion into the sclera canal in sheep, pig, monkey, and human

Microstructural evidence that lamina cribrosa beams (LC), peripapillary sclera (PPS) and central retinal artery (CRA) have distinct mechanical behaviors when stretched

Adaptation and visual comfort in children with new spectacle lenses containing concentric rings of contiguous aspherical micro-lenses for myopia control

Comparison of multi-retinal layer segmentation vs. existing segmentation in CIRRUS OCT images

Agrin Promotes Limbal Stem Cell Proliferation and Corneal Wound Healing Through Hippo-Yap Signaling Pathway

Real-time measurement of lamina cribrosa and sclera collagen architecture and mechanics at sub-micron resolution

Drusen Dynamics using Optical Coherence Tomography (OCT)

Collagen fiber interweaving strongly influences sclera stiffness, and likely plays a central role in globe mechanics

OCT in Neonate Monkeys With and Without Maternal Zika Virus Exposure

CNV lesion OCT segmentation in a clinical trial of wet AMD

Performance of a Novel OCT Segmentation Method for Determining Lesion Volume in the Assessment of a Non-Human Primate Model of Choroidal Neovascularization

The Effect of Different Optical Corrections on Accommodation of Myopic Children

Performance evaluation of multi-retinal layer segmentation using SD-OCT

Impaired Autophagic Degradation of Transforming Growth Factor-β-Induced Protein by Macrophages in Lattice Corneal Dystrophy

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