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Retinal Cell Biology January 2025

DNA-Dependent Protein Kinase Catalytic Subunit Prevents Ferroptosis in Retinal Pigment Epithelial Cells

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Xueying Wang; Xi Wang; Zhenzhen Zhao; Qian Wang; Xiaoman Zhu; Qingjian Ou; Jing-Ying Xu; Lixia Lu; Furong Gao; Juan Wang; Yanlong Bi; Guo-Tong Xu; Caixia Jin; Haibin Tian
TAGS: ferroptosis, prkdc gene, retinal pigment cell, catalytic domain, dna damage, phosphorylation
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):50. https://doi.org/10.1167/iovs.66.1.50

Includes: Supplemental Content

Retina October 2024

Roflumilast Attenuates Microglial Senescence and Retinal Inflammatory Neurodegeneration Post Retinal Ischemia Reperfusion Injury Through Inhibiting NLRP3 Inflammasome

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Chunlian Ou; Yiwei Lin; Jing Wen; Hongyang Zhang; Ying Xu; Naiyuan Zhang; Qiong Liu; Yingzi Wu; Jing Xu; Jing Wu
TAGS: aging, inflammasomes, nerve degeneration, nlr family, pyrin domain-containing 3 protein, older adult, reperfusion injury, retinal ischemia, roflumilast, wounds and injuries, microglia
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):38. https://doi.org/10.1167/iovs.65.12.38

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Effective treatment of optic neuropathies by intraocular delivery of MSC-sEVs through augmenting the G-CSF-macrophage pathway

Wei Yi; Ying Xue; Wenjie Qing; Yingxue Cao; Lingli Zhou; Mingming Xu; Zehui Sun; Yuying Li; Xiaomei Mai; Le Shi; Chang He; Feng Zhang; Elia J Duh; Yihai Cao; Xialin Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):678.

ARVO Annual Meeting Abstract June 2024

A Spontaneous Nonhuman Primate Model of Best Vitelliform Macular Dystrophy

mingming Xu; Ying Xue; Yingxue Cao; Ziqi Yang; Zehui Sun; Xiaomei Mai; Le Shi; Wenjie Qing; Yuying Li; Wei Yi; Xialin Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6037.

ARVO Annual Meeting Abstract June 2024

Electroretinography with the RM Electrode: Normal Values, Variation with Age and Comparison with the Burian-Allen Electrode

Brett Jeffrey; Xueyang Ying; Christina Appleman; Suy Sobany; Anna Papadogiannis; Daniel Claus; Laryssa Huryn; Marisa P Boyle; Wadih M Zein; Brian Patrick Brooks

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5859.

Anatomy and Pathology/Oncology August 2023

Nonhuman Primate Eyes Display Variable Growth and Aging Rates in Alignment With Human Eyes

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Ying Xue; Yingxue Cao; Shuxin Fan; Mingming Xu; Ziqi Yang; Lingli Zhou; Le Shi; Lechun Ou; Yuying Li; Wenjie Qing; Zhicheng Zou; Fuxiang Mao; Ningli Wang; Elia J. Duh; Wei Yi; Xialin Liu
TAGS: aging, biometry, eye, lens (device), lens, crystalline, macaca, primates, regression analysis
Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):23. https://doi.org/10.1167/iovs.64.11.23

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Integrated genomics and proteomics analysis reveal the regulatory role of miR-10b targets in normal and diabetic human limbal epithelial cells

Nagendra Verma; Adam Poe; Andrew Fealy; Mariam Ebrahami; Anokhi Patel; Ying Song Xue; Santiskulvong Chintda; Alex Rajewski; Sun Ren; Kevin Tseng; Sungyong You; Alexander V. Ljubimov; Mehrnoosh Saghizadeh

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3101.

Artificial Intelligence January 2023

Deep Learning-Based System for Disease Screening and Pathologic Region Detection From Optical Coherence Tomography Images

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Xiaoming Chen; Ying Xue; Xiaoyan Wu; Yi Zhong; Huiying Rao; Heng Luo; Zuquan Weng
TAGS: deep learning, learning, optical coherence tomography, retinal diseases, screening
Trans. Vis. Sci. Tech.. 2023; 12(1):29. https://doi.org/10.1167/tvst.12.1.29

Includes: Supplemental Content

Special Issue December 2020

DeepRetina: Layer Segmentation of Retina in OCT Images Using Deep Learning

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Qiaoliang Li; Shiyu Li; Zhuoying He; Huimin Guan; Runmin Chen; Ying Xu; Tao Wang; Suwen Qi; Jun Mei; Wei Wang

Trans. Vis. Sci. Tech.. 2020; 9(2):61. https://doi.org/10.1167/tvst.9.2.61

Special Issue June 2020

Automated Recognition of Retinal Pigment Epithelium Cells on Limited Training Samples Using Neural Networks

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Qitong Gao; Ying Xu; Joshua Amason; Anna Loksztejn; Scott Cousins; Miroslav Pajic; Majda Hadziahmetovic
TAGS: retinal pigment cell, retinal pigment epithelium, training, cell culture techniques, datasets, mice, choroid
Trans. Vis. Sci. Tech.. 2020; 9(2):31. https://doi.org/10.1167/tvst.9.2.31

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Transplantation site affects the outcome of adipose-derived stem cell-based therapy for retinal degeneration

Haibin Tian; Furong Gao; Caixia Jin; Jing-Ying Xu; Juan Wang; Jieping Zhang; Jingfa Zhang; Lixia LYU; Guo-Tong Xu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):803.

ARVO Annual Meeting Abstract June 2020

Deep Learning Approach for Automated Recognition of Retinal Pigment Epithelium Cell

Majda Hadziahmetovic; Qitong Gao; Ying Xu; Joshua Amason; Anna Loksztejn; Scott W Cousins; Miroslav Pajic

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2030.

Articles March 2020

Angiopoietin-1 Knockout Mice as a Genetic Model of Open-Angle Glaucoma

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Benjamin R. Thomson; Marta Grannonico; Feng Liu; Mingna Liu; Parrykumar Mendapara; Ying Xu; Xiaorong Liu; Susan E. Quaggin
TAGS: angiopoietins, mice, mice, knockout, models, genetic, open-angle glaucoma, glaucoma, retina, intraocular pressure
Trans. Vis. Sci. Tech.. 2020; 9(4):16. https://doi.org/10.1167/tvst.9.4.16

Includes: Supplemental Content

Retinal Cell Biology February 2020

Protein Kinase A Inhibitor H89 Attenuates Experimental Proliferative Vitreoretinopathy

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Yali Lyu; Wei Xu; Jieping Zhang; Mengwen Li; Qingyi Xiang; Yao Li; Tianhao Tan; Qingjian Ou; Jingfa Zhang; Haibin Tian; Jing-Ying Xu; Caixia Jin; Furong Gao; Juan Wang; Weiye Li; Ao Rong; Lixia Lu; Guo-Tong Xu
TAGS: attenuation, cyclic amp-dependent protein kinases, epithelial to mesenchymal transition, gel, proteins, tissue membrane, vitreoretinopathy, proliferative, collagen, pathogenesis, rats
Invest. Ophthalmol. Vis. Sci.. 2020; 61(2):1. https://doi.org/10.1167/iovs.61.2.1

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

The population-based epidemiology of ocular diseases in multiple sclerosis

Sarah Chao Ying Xu; Eoin Flanagan; Feng Wang; Jacqueline Leavitt; John J Chen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):622.

ARVO Annual Meeting Abstract July 2018

A cell culture condition that induces the mesenchymal-epithelial transition of dedifferentiated porcine retinal pigment epithelial cells

Haibin Tian; Jing-Ying Xu; Caixia Jin; Furong Gao; Juan Wang; Jieping Zhang; Jingfa Zhang; Weiye Li; Lixia Lu; Guo-Tong Xu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3093.

ARVO Annual Meeting Abstract July 2018

Inhibition of non-NMDA ionotropic glutamate receptors delays the retinal degeneration in rd10 mouse

Ying Xu; Zongqin Xiang; Yiqin Bao; Jia Zhang; Jun Dong; Yibo Qu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5282.

ARVO Annual Meeting Abstract July 2018

ATF3 inhibiting ASNS expression Contributes to Naphthalene Induced Cataract Development

Jing-Ying Xu; Yiting YANG; Peng Shang; Chaoyang Zhang; qingjian Ou; Furong Gao; Haibin Tian; Caixia Jin; Lixia Lu; Guo-Tong Xu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5644.

ARVO Annual Meeting Abstract July 2018

Generating and Maintaining Retinal Progenitor Cells from Adult Mouse Retina

Caixia Jin; qingjian Ou; Haibin Tian; Juan Wang; Jing-Ying Xu; Lixia Lu; Guo-Tong Xu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4576.

Retina January 2018

Lycium Barbarum Polysaccharides Protect Retina in rd1 Mice During Photoreceptor Degeneration

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Feng Liu; Jia Zhang; Zongqin Xiang; Di Xu; Kwok-Fai So; Noga Vardi; Ying Xu
TAGS: mice, photoreceptors, polysaccharides, retina, tissue degeneration, painful bladder syndrome
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):597-611. https://doi.org/10.1167/iovs.17-22881

Includes: Supplemental Content

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DNA-Dependent Protein Kinase Catalytic Subunit Prevents Ferroptosis in Retinal Pigment Epithelial Cells

Roflumilast Attenuates Microglial Senescence and Retinal Inflammatory Neurodegeneration Post Retinal Ischemia Reperfusion Injury Through Inhibiting NLRP3 Inflammasome

Effective treatment of optic neuropathies by intraocular delivery of MSC-sEVs through augmenting the G-CSF-macrophage pathway

A Spontaneous Nonhuman Primate Model of Best Vitelliform Macular Dystrophy

Electroretinography with the RM Electrode: Normal Values, Variation with Age and Comparison with the Burian-Allen Electrode

Nonhuman Primate Eyes Display Variable Growth and Aging Rates in Alignment With Human Eyes

Integrated genomics and proteomics analysis reveal the regulatory role of miR-10b targets in normal and diabetic human limbal epithelial cells

Deep Learning-Based System for Disease Screening and Pathologic Region Detection From Optical Coherence Tomography Images

DeepRetina: Layer Segmentation of Retina in OCT Images Using Deep Learning

Automated Recognition of Retinal Pigment Epithelium Cells on Limited Training Samples Using Neural Networks

Transplantation site affects the outcome of adipose-derived stem cell-based therapy for retinal degeneration

Deep Learning Approach for Automated Recognition of Retinal Pigment Epithelium Cell

Angiopoietin-1 Knockout Mice as a Genetic Model of Open-Angle Glaucoma

Protein Kinase A Inhibitor H89 Attenuates Experimental Proliferative Vitreoretinopathy

The population-based epidemiology of ocular diseases in multiple sclerosis

A cell culture condition that induces the mesenchymal-epithelial transition of dedifferentiated porcine retinal pigment epithelial cells

Inhibition of non-NMDA ionotropic glutamate receptors delays the retinal degeneration in rd10 mouse

ATF3 inhibiting ASNS expression Contributes to Naphthalene Induced Cataract Development

Generating and Maintaining Retinal Progenitor Cells from Adult Mouse Retina

Lycium Barbarum Polysaccharides Protect Retina in rd1 Mice During Photoreceptor Degeneration

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