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ARVO Annual Meeting Abstract July 2019

Increased expression of IGFBP2 induces RPE and photoreceptor degeneration at senescence

Sandeep Kumar; Amrita Fnu; Mackenzie Parker; Glenwood G Gum; Vatsala Naageshwaran; Yingbin Fu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2969. doi:

ARVO Annual Meeting Abstract July 2019

AIBP suppresses choroidal neovascularization (CNV) by enhancing cholesterol efflux

Yingbin Fu; Mackenzie Parker; Ling-Ping Zhu; Qing Yan; Nduka Enemchukwu; Jun-dae Kim; Longhou Fang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3272. doi:

ARVO Annual Meeting Abstract July 2018

The pathogenesis of polypoidal choroidal vasculopathy proceeds via a two-stage process

Yingbin Fu; Sandeep Kumar; Hiroyuki Nakashizuka; Alex Jones; Alyssia Lambert; Xuchen Zhao; Megan Shen; Mackenzie Parker; Mark O M Tso; Jon Rainier

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):346. doi:

ARVO Annual Meeting Abstract July 2018

Elevated Intracranial Pressure in Mice Causes Retinal Ganglion Cell Loss, Dysfunction, and Hypoxia

Benjamin J Frankfort; Guofu Shen; Schuyler Link; Sandeep Kumar; Derek Nusbaum; Dennis Tse; Yingbin Fu; Samuel M Wu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2193. doi:

ARVO Annual Meeting Abstract June 2017

Genetic deletion of M-opsin prevents “M-cone” degeneration in a mouse model of Leber congenital amaurosis

HUI XU; Nduka Enemchukwu; Yingbin Fu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4516. doi:

ARVO Annual Meeting Abstract June 2017

Long term protection of cone photoreceptors in a mouse model of Leber congenital amaurosis-1 by deletion of S-opsin

Nduka Enemchukwu; HUI XU; Mackenzie Parker; Lynn Zhu; Yingbin Fu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4530. doi:

ARVO Annual Meeting Abstract September 2016

Genetic deletion of S-opsin prevents rapid cone photoreceptor degeneration in the Guanylate Cyclase-1 knockout model of Leber congenital amaurosis

Nduka Enemchukwu; Sam Ham; Yingbin Fu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):174. doi:

ARVO Annual Meeting Abstract September 2016

CRISPR/dCas9 to treat neovascular age-related macular degeneration

Katie L Pennington; Sandeep Kumar; Alex Jones; Margaret M DeAngelis; Yingbin Fu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4436. doi:

ARVO Annual Meeting Abstract September 2016

Focal ERG analysis on the impact of PCV lesions on retinal function

Sandeep Kumar; Stephanie VanBeuge; Zachary Berriochoa; Amrita .; Yingbin Fu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract June 2015

Efficient deletion of the IGFBP domain of multifunctional serine protease HTRA1 by CRISPR/Cas9

HUI XU; Sandeep Kumar; Yingbin Fu

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2363. doi:

ARVO Annual Meeting Abstract June 2015

Inflammation plays an important role in the pathogenesis of Polypoidal Choroidal Vasculopathy

Sandeep Kumar; Alex Jones; Shixian Wang; Zachary Berriochoa; Yingbin Fu

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4196. doi:

ARVO Annual Meeting Abstract June 2015

Genetic deletion of S-opsin provides long-term protection of cone photoreceptors in a mouse model of Leber congenital amaurosis

Nduka O Enemchukwu; Tao Zhang; Alex Jones; Shixian Wang; Emily Dennis; Carl B Watt; Edward Pugh; Yingbin Fu

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5478. doi:

Research Highlight October 2014

A Functional Approach to Examine the Role of HTRA1 Versus ARMS2 in AMD

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Yingbin Fu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(10):6524. doi: https://doi.org/10.1167/iovs.14-15670

Multidisciplinary Ophthalmic Imaging June 2014

Angiographic Features of Transgenic Mice With Increased Expression of Human Serine Protease HTRA1 in Retinal Pigment Epithelium

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Sandeep Kumar; Zachary Berriochoa; Balamurali K Ambati; Yingbin Fu
TAGS: angiogram, htra1 gene, mice, mice, transgenic, ophthalmoscopy, retinal pigment epithelium, serine endopeptidases, polyps, animal model, phenotype
Invest. Ophthalmol. Vis. Sci.. 2014; 55(6):3842-3850. doi: https://doi.org/10.1167/iovs.13-13111

ARVO Annual Meeting Abstract April 2014

Histopathological characterization of different lesion types of polypoidal choroidal vasculopathy in HTRA1 transgenic mice

Alex Jones; Sandeep Kumar; Shixian Wang; Zachary Berriochoa; Yingbin Fu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1184. doi:

ARVO Annual Meeting Abstract April 2014

Angiographic features of transgenic mice with increased expression of human serine protease HTRA1 in retinal pigment epithelium

Sandeep Kumar; Zachary Berriochoa; Alex Jones; Yingbin Fu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5237. doi:

ARVO Annual Meeting Abstract June 2013

Genetic deletion of S-opsin prevents rapid cone degeneration in a mouse model of Leber congenital amaurosis

Tao Zhang; Alex Jones; Shixian Wang Wang; Edward Pugh; Wolfgang Baehr; Yingbin Fu

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4190. doi:

ARVO Annual Meeting Abstract June 2013

The proteolytic activity of HTRA1 is responsible for its pathological role in polypoidal choroidal vasculopathy

Sandeep Kumar; Alex Jones; Zach Berriochoa; Shixian Wang Wang; Yingbin Fu

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4991. doi:

ARVO Annual Meeting Abstract June 2013

Conditional ablation of VEGFR-1 in photoreceptors induces retinal angiomatous proliferation: A transgenic mouse model of AMD

Ling Luo; Xiaohui Zhang; Subrata Das; Hironori Uehara; Tad Miya; Thomas Olsen; Bonnie Archer; Yingbin Fu; Wolfgang Baehr; Balamurali Ambati

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4995. doi:

Biochemistry and Molecular Biology June 2012

Chemical Chaperone TUDCA Preserves Cone Photoreceptors in a Mouse Model of Leber Congenital Amaurosis

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Tao Zhang; Wolfgang Baehr; Yingbin Fu
TAGS: leber's amaurosis, mice, molecular chaperones, retinal cone, retina, membrane proteins
Invest. Ophthalmol. Vis. Sci.. 2012; 53(7):3349-3356. doi: https://doi.org/10.1167/iovs.12-9851

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Increased expression of IGFBP2 induces RPE and photoreceptor degeneration at senescence

AIBP suppresses choroidal neovascularization (CNV) by enhancing cholesterol efflux

The pathogenesis of polypoidal choroidal vasculopathy proceeds via a two-stage process

Elevated Intracranial Pressure in Mice Causes Retinal Ganglion Cell Loss, Dysfunction, and Hypoxia

Genetic deletion of M-opsin prevents “M-cone” degeneration in a mouse model of Leber congenital amaurosis

Long term protection of cone photoreceptors in a mouse model of Leber congenital amaurosis-1 by deletion of S-opsin

Genetic deletion of S-opsin prevents rapid cone photoreceptor degeneration in the Guanylate Cyclase-1 knockout model of Leber congenital amaurosis

CRISPR/dCas9 to treat neovascular age-related macular degeneration

Focal ERG analysis on the impact of PCV lesions on retinal function

Efficient deletion of the IGFBP domain of multifunctional serine protease HTRA1 by CRISPR/Cas9

Inflammation plays an important role in the pathogenesis of Polypoidal Choroidal Vasculopathy

Genetic deletion of S-opsin provides long-term protection of cone photoreceptors in a mouse model of Leber congenital amaurosis

A Functional Approach to Examine the Role of HTRA1 Versus ARMS2 in AMD

Angiographic Features of Transgenic Mice With Increased Expression of Human Serine Protease HTRA1 in Retinal Pigment Epithelium

Histopathological characterization of different lesion types of polypoidal choroidal vasculopathy in HTRA1 transgenic mice

Angiographic features of transgenic mice with increased expression of human serine protease HTRA1 in retinal pigment epithelium

Genetic deletion of S-opsin prevents rapid cone degeneration in a mouse model of Leber congenital amaurosis

The proteolytic activity of HTRA1 is responsible for its pathological role in polypoidal choroidal vasculopathy

Conditional ablation of VEGFR-1 in photoreceptors induces retinal angiomatous proliferation: A transgenic mouse model of AMD

Chemical Chaperone TUDCA Preserves Cone Photoreceptors in a Mouse Model of Leber Congenital Amaurosis

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