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Retina December 2024

Multi-Omics Integration With Machine Learning Identified Early Diabetic Retinopathy, Diabetic Macula Edema and Anti-VEGF Treatment Response

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Yuhui Pang; Chaokun Luo; Qingruo Zhang; Xiongze Zhang; Nanying Liao; Yuying Ji; Lan Mi; Yuhong Gan; Yongyue Su; Feng Wen; Hui Chen
TAGS: anti-vascular endothelial growth factor therapy, diabetes mellitus, diabetic retinopathy, edema, machine learning, multiomics, macula lutea, hypertension, nonproliferative diabetic retinopathy, metabolomics
Trans. Vis. Sci. Tech.. 2024; 13(12):23. https://doi.org/10.1167/tvst.13.12.23

Includes: Supplemental Content

Retina August 2024

Molecular Responses of Anti-VEGF Therapy in Neovascular Age-Related Macular Degeneration: Integrative Insights From Multi-Omics and Clinical Imaging

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Xuenan Zhuang; Miaoling Li; Lan Mi; Xiongze Zhang; Jiaxin Pu; Guiqin He; Liang Zhang; Honghua Yu; Liwei Yao; Hui Chen; Yuying Ji; Chengguo Zuo; Yongyue Su; Yuhong Gan; Xinlei Hao; Yining Zhang; Xuelin Chen; Feng Wen
TAGS: anti-vascular endothelial growth factor therapy, exudative age-related macular degeneration, molecule, diagnostic imaging, hypertension, metabolites, metabolomics, multiomics, proteins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):24. https://doi.org/10.1167/iovs.65.10.24

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Translating Rodent Infrared Reflectance (IR) Fundus Image to Human IR Image using Generative Artificial Intelligence

Jennifer J Kang-Mieler; Xueshen Li; Mohammed Attia; Chaimae Gouya; Yu Gan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3752.

Retina May 2024

Diurnal Variation in Choroidal Parameters Among Healthy Subjects Using Wide-Field Swept-Source Optical Coherence Tomography Angiography

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Guiqin He; Xiongze Zhang; Xuenan Zhuang; Yunkao Zeng; Xuelin Chen; Yuhong Gan; Yongyue Su; Yining Zhang; Feng Wen
TAGS: angiogram, circadian rhythms, optical coherence tomography
Trans. Vis. Sci. Tech.. 2024; 13(5):16. https://doi.org/10.1167/tvst.13.5.16

Retina February 2024

A Novel Exploration of the Choroidal Vortex Vein System: Incidence and Characteristics of Posterior Vortex Veins in Healthy Eyes

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Guiqin He; Xiongze Zhang; Xuenan Zhuang; Yunkao Zeng; Yuhong Gan; Yongyue Su; Miaoling Li; Yuying Ji; Lan Mi; Xuelin Chen; Feng Wen
TAGS: eye, incidence
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):21. https://doi.org/10.1167/iovs.65.2.21

Includes: Supplemental Content

Retina August 2023

Choroidal Vein Alterations in Pachychoroid Disease With Choroidal Vascular Hyperpermeability: Evaluated by Wide-Field Indocyanine Green Angiography

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Guiqin He; Xiongze Zhang; Yuhong Gan; Miaoling Li; Xuenan Zhuang; Yunkao Zeng; Yongyue Su; Xuelin Chen; Feng Wen
TAGS: central serous chorioretinopathy, eye, indocyanine green angiography, anastomosis, surgical
Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):25. https://doi.org/10.1167/iovs.64.11.25

ARVO Annual Meeting Abstract June 2023

αA-Crystallin Interacts with TBK1 to Modulate NF-κB Pathway in Mediating Stress-Induced Changes of the Immune Microenvironment and Inflammatory Responses in the Ocular Lens

David W Li; Min Hou; Qian Nie; Jing-Miao Wang; Shuyu Zheng; Yan Wang; Jialing Fu; LAN ZHANG; Xuebin Hu; yuan xiao; Xingmiao Liang; yuwen gan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5117.

ARVO Annual Meeting Abstract June 2023

AlphaA-Crystallin Suppresses DBC1, A Negative Regulator of SIRT1 to Repress Stress-Induced Apoptosis of Lens Epithelial Cells

Yan Wang; Jialing Fu; Shuyu Zheng; Jingmiao Wang; yuan xiao; LAN ZHANG; Xuebin Hu; yuwen gan; Xingmiao Liang; David W Li

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):526.

ARVO Annual Meeting Abstract June 2023

S133A-CREB Acts As A Novel Transcription Factor to Regulate EMT in Lens Epithelial Cells

LAN ZHANG; Xuebin Hu; yuan xiao; Yueyue Bai; Jialing Fu; Yan Wang; Shuyu Zheng; Jingmiao Wang; yuwen gan; Xingmiao Liang; David W Li

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1947.

ARVO Annual Meeting Abstract June 2023

MYPT1 Dephosphorylates HMGA1a to Regulates p53-Mediated Apoptosis in Zebrafish Retina and Lens

Xuebin Hu; LAN ZHANG; Jialing Fu; Yan Wang; Shuyu Zheng; Jingmiao Wang; yuan xiao; Xinmiao Liang; yuwen gan; David W Li

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3638.

ARVO Annual Meeting Abstract June 2023

HSP90β Regulates Cell Proliferation through Interaction with the charged multivesicular body protein 4B (CHMP4B), A Novel Client Protein

Jialing Fu; Shuyu Zheng; Yan Wang; Jingmiao Wang; yuan xiao; LAN ZHANG; Xuebin Hu; yuwen gan; Xingmiao Liang; David W Li

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4134.

ARVO Annual Meeting Abstract June 2023

AlphaA-Crystallin Modulates cGAS/STING Pathway to Regulate the Immune Microenvironment in the Ocular Lens

Shuyu Zheng; Jialing Fu; Yan Wang; Jingmiao Wang; yuan xiao; LAN ZHANG; Xuebin Hu; yuwen gan; Xingmiao Liang; David W Li

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4133.

ARVO Annual Meeting Abstract June 2023

HSP90β Regulates the Inflammatory Response of the Ocular Lens through the NF-kB Pathway

Jingmiao Wang; Jialing Fu; Yan Wang; Shuyu Zheng; LAN ZHANG; Xuebin Hu; yuan xiao; Xingmiao Liang; yuwen gan; David W Li

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4132.

ARVO Annual Meeting Abstract June 2022

Sumoylated Pax6 Regulates Lens Stalk Regression During Lens Development

David W Li; Jialing Fu; Fangyuan Liu; Shuyu Zheng; Yan Wang; Jingmiao Wang; yuan xiao; Jiawen Xiang; Yuwen Gan; Xingmiao Liang

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):836.

ARVO Annual Meeting Abstract June 2022

The SP Family Transcription Factors Act As Major Regulators in the Transcription of the Major Heat Shock Protein, HSP90β in lens epithelial cells

Jialing Fu; Jingmiao Wang; yuan xiao; Yan Wang; Shuyu Zheng; Jiawen Xiang; Yuwen Gan; Xingmiao Liang; David W Li

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):651 – F0006.

ARVO Annual Meeting Abstract June 2022

Differential Expression of the SP Family Transcription Factors in Normal Human Lens and Cataract Patients

Jingmiao Wang; Jialing Fu; Yan Wang; Shuyu Zheng; yuan xiao; Jiawen Xiang; Yuwen Gan; Xingmiao Liang; David W Li

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4041 – F0005.

Retina November 2020

Identification of NLRP3 Inflammation-Related Gene Promoter Hypomethylation in Diabetic Retinopathy

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Hui Chen; Xiongze Zhang; Nanying Liao; Yuying Ji; Lan Mi; Yuhong Gan; Yongyue Su; Feng Wen

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):12. https://doi.org/10.1167/iovs.61.13.12

Includes: Supplemental Content

Retina October 2018

Drusen and Age-Related Scattered Hypofluorescent Spots on Late-Phase Indocyanine Green Angiography, a Candidate Correlate of Lipid Accumulation

PDF

Ling Chen; Xiongze Zhang; Miaoling Li; Yuhong Gan; Feng Wen
TAGS: drusen, indocyanine green angiography, lipids
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5237-5245. https://doi.org/10.1167/iovs.18-25124

Immunology and Microbiology September 2018

Disabled-2 (DAB2) Overexpression Inhibits Monocyte-Derived Dendritic Cells' Function in Vogt-Koyanagi-Harada Disease

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Shenglan Yi; Rui Chang; Jianping Hu; Yiguo Qiu; Qingfeng Wang; Qingfeng Cao; Gangxiang Yuan; Guannan Su; Chunjiang Zhou; Yao Wang; Aize Kijlstra; Peizeng Yang
TAGS: dendritic cells, disabled persons, monocytes, protein overexpression, proteins, uveomeningoencephalitic syndrome, interleukin-6, tumor necrosis factors
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4662-4669. https://doi.org/10.1167/iovs.18-24630

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Hypermethylation of Interferon Regulatory Factor 8 (IRF8) confers risk to Vogt-Koyanagi-Harada Disease

Yiguo Qiu; Hongsong Yu; Yunyun Zhu; Zi Ye; Jing Deng; Wencheng Su; Qingfeng Cao; Gangxiang Yuan; Aize Kijlstra; Peizeng Yang

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):506.

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Multi-Omics Integration With Machine Learning Identified Early Diabetic Retinopathy, Diabetic Macula Edema and Anti-VEGF Treatment Response

Molecular Responses of Anti-VEGF Therapy in Neovascular Age-Related Macular Degeneration: Integrative Insights From Multi-Omics and Clinical Imaging

Translating Rodent Infrared Reflectance (IR) Fundus Image to Human IR Image using Generative Artificial Intelligence

Diurnal Variation in Choroidal Parameters Among Healthy Subjects Using Wide-Field Swept-Source Optical Coherence Tomography Angiography

A Novel Exploration of the Choroidal Vortex Vein System: Incidence and Characteristics of Posterior Vortex Veins in Healthy Eyes

Choroidal Vein Alterations in Pachychoroid Disease With Choroidal Vascular Hyperpermeability: Evaluated by Wide-Field Indocyanine Green Angiography

αA-Crystallin Interacts with TBK1 to Modulate NF-κB Pathway in Mediating Stress-Induced Changes of the Immune Microenvironment and Inflammatory Responses in the Ocular Lens

AlphaA-Crystallin Suppresses DBC1, A Negative Regulator of SIRT1 to Repress Stress-Induced Apoptosis of Lens Epithelial Cells

S133A-CREB Acts As A Novel Transcription Factor to Regulate EMT in Lens Epithelial Cells

MYPT1 Dephosphorylates HMGA1a to Regulates p53-Mediated Apoptosis in Zebrafish Retina and Lens

HSP90β Regulates Cell Proliferation through Interaction with the charged multivesicular body protein 4B (CHMP4B), A Novel Client Protein

AlphaA-Crystallin Modulates cGAS/STING Pathway to Regulate the Immune Microenvironment in the Ocular Lens

HSP90β Regulates the Inflammatory Response of the Ocular Lens through the NF-kB Pathway

Sumoylated Pax6 Regulates Lens Stalk Regression During Lens Development

The SP Family Transcription Factors Act As Major Regulators in the Transcription of the Major Heat Shock Protein, HSP90β in lens epithelial cells

Differential Expression of the SP Family Transcription Factors in Normal Human Lens and Cataract Patients

Identification of NLRP3 Inflammation-Related Gene Promoter Hypomethylation in Diabetic Retinopathy

Drusen and Age-Related Scattered Hypofluorescent Spots on Late-Phase Indocyanine Green Angiography, a Candidate Correlate of Lipid Accumulation

Disabled-2 (DAB2) Overexpression Inhibits Monocyte-Derived Dendritic Cells' Function in Vogt-Koyanagi-Harada Disease

Hypermethylation of Interferon Regulatory Factor 8 (IRF8) confers risk to Vogt-Koyanagi-Harada Disease

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