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ARVO Annual Meeting Abstract June 2022

Granzyme B Proteolyzes Thrombospondin-1 in RPE Cells and Choroidal Neovascularization

Gideon Obasanmi; Matthew R Zeglinski; Erika Yuan Tian; Eleanor To; Jing Z Cui; David Granville; Joanne A Matsubara

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):473 – A0010. doi:

ARVO Annual Meeting Abstract June 2022

Preclinical evaluation of RTC-1119, a surface eroding intracameral implant composed entirely of a latanoprost acid prodrug, for long-term intraocular pressure control

Ike Ahmed; Kyle Battiston; Shadi Taghavi; Hans Fischer; Emily Baldwin; Matthew Statham; Jonathan Day; Adam Daley; Ben Muirhead; Emily Anne Hicks; Jennifer Jing Yuan Tian; Heather Sheardown; Ian Parrag; Wendy Naimark

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):442. doi:

ARVO Annual Meeting Abstract June 2022

Hyaluronic Acid based Therapeutic Bandage Contact Lenses for Corneal Wound Healing

Jennifer Jing Yuan Tian; Lina Liu; Mitchell Ross; Heather Sheardown

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3222 – A0257. doi:

ARVO Annual Meeting Abstract June 2021

Granzyme B degrades extracellular matrix and promotes choroidal neovascularization in an ex-vivo microvascular angiogenesis model

Gideon Obasanmi; Yuan Tian; Jing Z Cui; Christopher T Turner; Matthew R Zeglinski; David J Granville; Joanne A Matsubara

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2709. doi:

ARVO Annual Meeting Abstract June 2020

Granzyme B Promotes Early Stages of AMD by Degrading Extracellular Matrix and Cell-Cell Contact Proteins in Bruch’s Membrane and RPE

Joanne A Matsubara; Miranda Tsuyuki; Jacob Ng; Erika Yuan Tian; Chao Zhu; Jing Z Cui; Sho Hiroyasu; Christopher T. Turner; Matthew R. Zeglinski; Trevor J McGill; Martha Neuringer; David J. Granville

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2285. doi:

ARVO Annual Meeting Abstract July 2019

Phenylboronic Acid Based Mucoadhesive Polymeric Micelles for Anterior Drug Delivery

Jennifer Jing Yuan Tian; Heather Sheardown; Naveed Yasin; Talena Rambarran; Lina Liu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3375. doi:

ARVO Annual Meeting Abstract July 2019

How the genetic evolution happened in Bechet’s diseases along the Silk Route: China, Turkery and United Kingdom?

Yuan Tian; Ana Poveda Gallego; Mothith Shamdas; Hedayat Javidi; Saaeha Rauz; Philip Ian Murray; Peizeng Yang; Graham R Wallace

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):817. doi:

ARVO Annual Meeting Abstract July 2019

Potential Role of Extracellular Granzyme B in the Pathogenesis of Age-related Macular Degeneration (AMD)

Joanne A Matsubara; Yuan Tian; Jing Z Cui; Sijia Cao; Sho Hiroyasu; Chris Turner; Yue Shen; David J. Granville

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1234. doi:

ARVO Annual Meeting Abstract July 2019

Deep learning approach to improve the efficiency and effectiveness of optical coherence tomography (OCT) scans

Lingling Wang; Jianchun Zhao; Xuan Zou; Xuan Chen; Chunhui Jiang; Xing Liu; Hui Xiao; Xiaoli Song; Yao Zhang; Jun Wu; Jie Wang; Dayong Ding; Junfeng Tan; Yuan Tian; Ningjiang Chen

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1514. doi:

ARVO Annual Meeting Abstract July 2019

The essential role of gene GALC and CASC16-CHD9 in the pathogenesis of Ocular mucous membrane pemphigoid (OcMMP)

Yuan Tian; Kaki Tsang; Gibran Farook Butt; John Dart; Saleh Ibrahim; Misa Hirose; Saaeha Rauz

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6706. doi:

Genetics April 2017

miRNA Copy Number Variants Confer Susceptibility to Acute Anterior Uveitis With or Without Ankylosing Spondylitis

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Lu Yang; Liping Du; Yingying Yue; Yike Huang; Qingyun Zhou; Shuang Cao; Jian Qi; Liang Liang; Lili Wu; Chaokui Wang; Zi Ye; Yuan Tian; Aize Kijlstra; Shengping Hou; Peizeng Yang
TAGS: ankylosing spondylitis, copy number polymorphism, disease susceptibility, micrornas, uveitis, anterior, cytokine, interleukin-6, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2017; 58(4):1991-2001. doi: https://doi.org/10.1167/iovs.16-21047

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Lutein supplementation leads to a decreased level of the circulating complement membrane attack complex sC5b-9.

Aize Kijlstra; Yuan Tian; Rob van der Veen; Maria Makridaki; Ian Murray; Tos TJM Berendschot

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):73. doi:

ARVO Annual Meeting Abstract April 2014

Lutein leads to a decrease of complement factor D (CFD) secretion by in vitro cultured mature adipocytes

Yuan Tian; Aize Kijlstra; Johan Renes; Tos TJM Berendschot

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):74. doi:

ARVO Annual Meeting Abstract June 2013

Lutein supplementation leads to a decreased level of circulating complement factors

Tos TJM Berendschot; Yuan Tian; Ian Murray; Maria Makridaki; Rob LP van der Veen; Aize Kijlstra

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4124. doi:

Immunology and Microbiology January 2013

IL-1β Triggered by Peptidoglycan and Lipopolysaccharide through TLR2/4 and ROS-NLRP3 Inflammasome–Dependent Pathways Is Involved in Ocular Behçet's Disease

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Liang Liang; Xiaoyu Tan; Qingyun Zhou; Yi Zhu; Yuan Tian; Hongsong Yu; Aize Kijlstra; Peizeng Yang
TAGS: behcet syndrome, inflammasomes, lipopolysaccharides, pathogenesis, peptidoglycan, toll-like receptor 2, toll-like receptor 4
Invest. Ophthalmol. Vis. Sci.. 2013; 54(1):402-414. doi: https://doi.org/10.1167/iovs.12-11047

Immunology and Microbiology September 2012

Effect of 1,25-Dihydroxyvitamin D3 on Th17 and Th1 Response in Patients with Behçet's Disease

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Yuan Tian; Chaokui Wang; Zi Ye; Xiang Xiao; Aize Kijlstra; Peizeng Yang
TAGS: behcet syndrome, interleukin-17, th17 cells, t-lymphocytes, interleukin-10, enzyme-linked immunosorbent assay, cytokine, mechlorethamine
Invest. Ophthalmol. Vis. Sci.. 2012; 53(10):6434-6441. doi: https://doi.org/10.1167/iovs.12-10398

Immunology and Microbiology July 2012

Decreased IL-27 Expression in Association with an Increased Th17 Response in Vogt-Koyanagi-Harada Disease

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Chaokui Wang; Yuan Tian; Bo Lei; Xiang Xiao; Zi Ye; Fuzhen Li; Aize Kijlstra; Peizeng Yang
TAGS: interleukin-27, uveomeningoencephalitic syndrome, interleukin-17, enzyme-linked immunosorbent assay
Invest. Ophthalmol. Vis. Sci.. 2012; 53(8):4668-4675. doi: https://doi.org/10.1167/iovs.12-9863

Includes: Supplemental Content

ARVO Annual Meeting Abstract March 2012

Decreased Interleukin-27 Expression is Associated with Active Uveitis in Behcet’s Disease

Peizeng Yang; Chaokui Wang; Yuan Tian; Zi Ye; Aize Kijlstra

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6905. doi:

ARVO Annual Meeting Abstract April 2011

CD4+ T Cells In Vogt-koyanagi-harada Disease Show A Decreased Stimulation Of IL-27 Expression By Dendritic Cells

Peizeng Yang; Chaokui Wang; Lichun Tian; Ju Shao; Fuzhen Li; Yuan Tian; Lei Bo; Shengping Hou; Kijlstra Aize

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):6638. doi:

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Granzyme B Proteolyzes Thrombospondin-1 in RPE Cells and Choroidal Neovascularization

Preclinical evaluation of RTC-1119, a surface eroding intracameral implant composed entirely of a latanoprost acid prodrug, for long-term intraocular pressure control

Hyaluronic Acid based Therapeutic Bandage Contact Lenses for Corneal Wound Healing

Granzyme B degrades extracellular matrix and promotes choroidal neovascularization in an ex-vivo microvascular angiogenesis model

Granzyme B Promotes Early Stages of AMD by Degrading Extracellular Matrix and Cell-Cell Contact Proteins in Bruch’s Membrane and RPE

Phenylboronic Acid Based Mucoadhesive Polymeric Micelles for Anterior Drug Delivery

How the genetic evolution happened in Bechet’s diseases along the Silk Route: China, Turkery and United Kingdom?

Potential Role of Extracellular Granzyme B in the Pathogenesis of Age-related Macular Degeneration (AMD)

Deep learning approach to improve the efficiency and effectiveness of optical coherence tomography (OCT) scans

The essential role of gene GALC and CASC16-CHD9 in the pathogenesis of Ocular mucous membrane pemphigoid (OcMMP)

miRNA Copy Number Variants Confer Susceptibility to Acute Anterior Uveitis With or Without Ankylosing Spondylitis

Lutein supplementation leads to a decreased level of the circulating complement membrane attack complex sC5b-9.

Lutein leads to a decrease of complement factor D (CFD) secretion by in vitro cultured mature adipocytes

Lutein supplementation leads to a decreased level of circulating complement factors

IL-1β Triggered by Peptidoglycan and Lipopolysaccharide through TLR2/4 and ROS-NLRP3 Inflammasome–Dependent Pathways Is Involved in Ocular Behçet's Disease

Effect of 1,25-Dihydroxyvitamin D3 on Th17 and Th1 Response in Patients with Behçet's Disease

Decreased IL-27 Expression in Association with an Increased Th17 Response in Vogt-Koyanagi-Harada Disease

Decreased Interleukin-27 Expression is Associated with Active Uveitis in Behcet’s Disease

CD4+ T Cells In Vogt-koyanagi-harada Disease Show A Decreased Stimulation Of IL-27 Expression By Dendritic Cells

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