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Retina March 2025

Evaluation of Suprachoroidal Injection in Cadaveric and Preclinical Models

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Mark Hedgeland; Sergio Camacho Gonzalez; Dimitrios Stampoulis; Vivian Lee; Kate Powell; Yubin Qiu; Robert Hodge; Greg Bell; Amanda Fago; Rebecca Atkinson-Dell; Nadya Choti; Kirsten Stoner
TAGS: injections, eye, subcutaneous injections
Trans. Vis. Sci. Tech.. 2025; 14(3):20. https://doi.org/10.1167/tvst.14.3.20

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract June 2024

Improving Preclinical Suprachoroidal Injections

Sergio Camacho Gonzalez; Dimitris Stampoulis; Kate Powell; Yubin Qiu; Atkinson-Dell Rebecca; Viv Lee; Nadya Choti; Nalini Rangaswamy; Sukhdeep Sahambi; Mark Hedgeland; Kirsten Stoner

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3976.

ARVO Annual Meeting Abstract June 2023

Immunohistochemical grading of human glaucomatous eye globes to ascertain disease severity and correlation with glial reactivity

Chuanxi Xiang; Manisha Mehta; Yubin Qiu; Christopher W. Wilson; Ganesh Prasanna

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1014.

ARVO Annual Meeting Abstract June 2023

Neither C3 nor FB knockout mice exhibit increased CNV size compared to littermate controls in a laser-induced wet AMD model

Yubin Qiu; Siyuan Shen; Elizabeth Fassbender; Bruce Jaffee; Chad E Bigelow; Stephen Poor

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2961.

ARVO Annual Meeting Abstract June 2023

ABCA1 activity in the RPE is unnecessary for RPE reverse cholesterol transport (RCT) and AMD pathophysiology

Matthew Coble; Jorge Aranda; John T Demirs; Robert Esterberg; Shawn Hanks; Sandra Jose; Barrett Leehy; Sha-Mei Liao; Yiyun Zhang; Sheng-Yong Niu; Yubin Qiu; Junzheng Yang

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3515.

Physiology and Pharmacology June 2021

Differential and Altered Spatial Distribution of Complement Expression in Age-Related Macular Degeneration

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John T. Demirs; Junzheng Yang; Maura A. Crowley; Michael Twarog; Omar Delgado; Yubin Qiu; Stephen Poor; Dennis S. Rice; Thaddeus P. Dryja; Karen Anderson; Sha-Mei Liao
TAGS: complement system proteins, eye, rna, messenger, age-related macular degeneration, choroid, neural retina, donors
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):26. https://doi.org/10.1167/iovs.62.7.26

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Transcriptional profiling of glaucoma donor retina using axon analysis for sample stratification

Ernie Hixon; Angela Banks; Nhi Vo; Yubin Qiu; Lin Fan; oleg Iartchouk; Ganesh Prasanna; Amy Chen

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2379.

ARVO Annual Meeting Abstract June 2021

Identification of a spontaneous mutation in Adiponectin receptor 1 in a complement factor H knockout mouse

JUNZHENG YANG; Angela Banks; Natasha M Buchanan; Sha-Mei Liao; Erika Lima; Nalini Rangaswamy; Ivana Arellano; Shawn Hanks; Joanna Vrouvlianis; Yubin Qiu; Dennis S Rice

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2948.

ARVO Annual Meeting Abstract June 2021

Aged mice with AMD-associated genetic mutations in complement or extracellular matrix do not exhibit slow dark adaptation

Shawn Hanks; Ivana Arellano; Erika Lima; Joanna Vrouvlianis; Yubin Qiu; Natasha M Buchanan; Siyuan Shen; Garrett Klokman; Maura Crowley; Chad Bigelow; Stephen Poor

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):242.

ARVO Annual Meeting Abstract June 2021

AAVHSCs, a Nuclease-Independent Approach for Transduction in Non-human Primate Brain and Retina and Editing of Retinal Cells in Human Organotypic Explants

Sumeet Sarin; Huei Mei Chen; Tania Seabrook; Rachel Resendes; Samitha Venu; Jeff Ellsworth; Jason Wright; Shiva Krupa; Christie Bell; Terri McGee; Yubin Qiu; David A Ammar; Nicholas Sprehe; Omar Francone; Jacinthe Gingras; Albert Seymour

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1469.

ARVO Annual Meeting Abstract June 2017

A topical VEGF inhibitor optimized for ocular indications

Stephen H Poor; Christopher Adams; Chad E Bigelow; Debby Long; Penny Yao; Elizabeth Fassbender; Siyuan Shen; Jim Chastain; Yubin Qiu; Bruce D Jaffee

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1975.

ARVO Annual Meeting Abstract September 2016

Ocular inflammatory cell infiltrates and angiogenesis are augmented by administration of the toll-like receptor-2 (TLR-2) ligand in a mouse model of choroidal neovascularization (CNV)

Stephen H Poor; Yubin Qiu; Adrian Will-Orrego; Elizabeth Fassbender; Siyuan Shen; Maura Crowley; Sha-Mei Liao; Bruce D Jaffee

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):484.

ARVO Annual Meeting Abstract September 2016

Systemic VEGF Inhibition does not modulate ocular inflammatory cell infiltrate in the murine laser-induced choroidal neovascularization (CNV) Model

Adrian Will-Orrego; Sha-Mei Liao; Yubin Qiu; Elizabeth Fassbender; Siyuan Shen; Namrata Kotagiri; Bruce D Jaffee; Stephen H Poor

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3323.

ARVO Annual Meeting Abstract June 2015

Weekly oral delivery of a vascular endothelial growth factor receptor (VEGFR) inhibitor compound optimized for ocular exposure improves safety and maintains efficacy compared to daily dosing

Yubin Qiu; Siyuan Shen; Elizabeth S Fassbender; Amber Woolfenden; Debby Long; Ron Newton; Erik Meredith; Bruce D Jaffee; Stephen H Poor; Ophthalmology, Novartis Institutes for BioMedical Research, Inc.

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):151.

ARVO Annual Meeting Abstract June 2015

A vascular endothelial growth factor receptor inhibitor (VEGFRi) achieves topical efficacy in rat and monkey models of choroidal neovascularization (CNV)

Stephen H Poor; Yubin Qiu; Amber Woolfenden; Debby Long; Christopher M Adams; Jason Elliott; Vinayak Hosagrahara; Jeremy M Sivak; Bruce D Jaffee

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3380.

Retina October 2014

Reliability of the Mouse Model of Choroidal Neovascularization Induced by Laser Photocoagulation

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Stephen H. Poor; Yubin Qiu; Elizabeth S. Fassbender; Siyuan Shen; Amber Woolfenden; Andrea Delpero; Yong Kim; Natasha Buchanan; Thomas C. Gebuhr; Shawn M. Hanks; Erik L. Meredith; Bruce D. Jaffee; Thaddeus P. Dryja
TAGS: choroidal neovascularization, lasers, light coagulation, mice, reliability
Invest. Ophthalmol. Vis. Sci.. 2014; 55(10):6525-6534. https://doi.org/10.1167/iovs.14-15067

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Intravitreal (IVT) injection exacerbates murine choroidal neovascularization (CNV) area by a MYD88 dependent mechanism

Elizabeth Fassbender; Yubin Qiu; Siyuan Shen; Amber Woolfenden; Andrea Delpero; Yong Kim; Bruce D Jaffee; Stephen H Poor

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1194.

ARVO Annual Meeting Abstract April 2014

Recombinant human vascular endothelial growth factor165(VEGF) derived from different expression systems does not affect in vitro, but does impact in vivo activity profiles

Yubin Qiu; Chad E Bigelow; Luciana Ferrara; Siyuan Shen; Michael P Maker; Elizabeth Fassbender; Yong Kim; Andrea DeErkenez; Barrett Leehy; Stephen H Poor

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):600.

ARVO Annual Meeting Abstract June 2013

EphA2 Stimulation of Angiogenesis is Dependent on VEGFR2

Luciana Ferrara; Andrea De Erkenez; Elizabeth Fassbender; Siyuan Shen; Amber Woolfenden; Yubin Qiu; Stephen Poor; Karen Anderson; Bruce Jaffee

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5613.

ARVO Annual Meeting Abstract June 2013

Validation and Characterization of Murine Oxygen-induced Retinopathy of Prematurity Model

Yubin Qiu; Amber Woolfenden; Wei Zheng; Karen Anderson; Melinda Hubbard; John Demirs; Joseph Loureiro; Joy Ghosh; Stephen Poor; Bruce Jaffee

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):617.

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Evaluation of Suprachoroidal Injection in Cadaveric and Preclinical Models

Improving Preclinical Suprachoroidal Injections

Immunohistochemical grading of human glaucomatous eye globes to ascertain disease severity and correlation with glial reactivity

Neither C3 nor FB knockout mice exhibit increased CNV size compared to littermate controls in a laser-induced wet AMD model

ABCA1 activity in the RPE is unnecessary for RPE reverse cholesterol transport (RCT) and AMD pathophysiology

Differential and Altered Spatial Distribution of Complement Expression in Age-Related Macular Degeneration

Transcriptional profiling of glaucoma donor retina using axon analysis for sample stratification

Identification of a spontaneous mutation in Adiponectin receptor 1 in a complement factor H knockout mouse

Aged mice with AMD-associated genetic mutations in complement or extracellular matrix do not exhibit slow dark adaptation

AAVHSCs, a Nuclease-Independent Approach for Transduction in Non-human Primate Brain and Retina and Editing of Retinal Cells in Human Organotypic Explants

A topical VEGF inhibitor optimized for ocular indications

Ocular inflammatory cell infiltrates and angiogenesis are augmented by administration of the toll-like receptor-2 (TLR-2) ligand in a mouse model of choroidal neovascularization (CNV)

Systemic VEGF Inhibition does not modulate ocular inflammatory cell infiltrate in the murine laser-induced choroidal neovascularization (CNV) Model

Weekly oral delivery of a vascular endothelial growth factor receptor (VEGFR) inhibitor compound optimized for ocular exposure improves safety and maintains efficacy compared to daily dosing

A vascular endothelial growth factor receptor inhibitor (VEGFRi) achieves topical efficacy in rat and monkey models of choroidal neovascularization (CNV)

Reliability of the Mouse Model of Choroidal Neovascularization Induced by Laser Photocoagulation

Intravitreal (IVT) injection exacerbates murine choroidal neovascularization (CNV) area by a MYD88 dependent mechanism

Recombinant human vascular endothelial growth factor165(VEGF) derived from different expression systems does not affect in vitro, but does impact in vivo activity profiles

EphA2 Stimulation of Angiogenesis is Dependent on VEGFR2

Validation and Characterization of Murine Oxygen-induced Retinopathy of Prematurity Model

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