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ARVO Annual Meeting Abstract June 2023

AAV dose-dependent transduction efficiency in RGCs and functional efficacy of CoChR3M-mediated vision restoration

QI LU; Anna Wright; Gary W Abrams; Zhuo-Hua Pan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):214.

Retinal Cell Biology October 2022

Targeted Expression of Retinoschisin by Retinal Bipolar Cells in XLRS Promotes Resolution of Retinoschisis Cysts Sans RS1 From Photoreceptors

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Camasamudram Vijayasarathy; Yong Zeng; Dario Marangoni; Lijin Dong; Zhuo-Hua Pan; Elizabeth M. Simpson; Robert N. Fariss; Paul A. Sieving
TAGS: cysts, mice, photoreceptors, retina, retinal bipolar cells, retinoschisis, spatial vectors
Invest. Ophthalmol. Vis. Sci.. 2022; 63(11):8. https://doi.org/10.1167/iovs.63.11.8

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Optogenetic approaches to restoring vision

Zhuo-Hua Pan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5.

ARVO Annual Meeting Abstract July 2019

Impact of retinal degeneration on restoring functional vision by optogenetics in rd mice

Zhuo-Hua Pan; Qi Lu; Mitchell Fenner; Tushar Harishkumar Ganjawala; Gary W Abrams

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6438.

ARVO Annual Meeting Abstract July 2018

Retinal ganglion cell targeting is more efficient than bipolar cell targeting for optogenetic vision restoration

Qi Lu; Tushar H. Ganjawala; Gary W Abrams; Zhuo-Hua Pan

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2590.

ARVO Annual Meeting Abstract July 2018

An ultra light-sensitive CoChR mutant restores functional vison in a blind mouse model under ambient light conditions

Tushar H. Ganjawala; Qi Lu; Mitchell D Fenner; Gary W Abrams; Zhuo-Hua Pan

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5988.

ARVO Annual Meeting Abstract July 2018

An unique subtype of BCs provides excitatory input to both ON and OFF synaptic pathways from both rods and cones in the retina

Ning Tian; Brent Young; Charu Ramakrishnan; Ping Wang; Karl Deisseroth; Tushar H. Ganjawala; Zhuo-Hua Pan

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2995.

Visual Neuroscience March 2018

A Robust Optomotor Assay for Assessing the Efficacy of Optogenetic Tools for Vision Restoration

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Qi Lu; Tushar H. Ganjawala; Samer Hattar; Gary W. Abrams; Zhuo-Hua Pan
TAGS: mice, miosis disorder, optogenetics, pupil constriction, vision, light intensity, photophobia
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1288-1294. https://doi.org/10.1167/iovs.17-23278

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract June 2015

Evaluation and Optimization of A Highly Light-Sensitive Channelrhodopsin CoChR for Vision Restoration

Tushar Harishkumar Ganjawala; Qi Lu; Anding Bi; Edward S Boyden; Zhuo-Hua Pan

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):997.

ARVO Annual Meeting Abstract April 2014

AAV-Mediated Expression Targeting of Retinal Rod Bipolar Cells with An Optimized mGluR6 Promoter

Zhuo-Hua Pan; Qi Lu; Tushar Ganjawala; JrGang Cheng

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2638.

ARVO Annual Meeting Abstract June 2013

Development and Evaluation of Highly Light-Sensitive Channelrhodopsin-2 Mutants for Vision Restoration

Zhuo-Hua Pan; Tushar Ganjawala; Zhifei Zhang; Qi Lu; Elena Ivanova

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5100.

ARVO Annual Meeting Abstract April 2011

Characterization Of Voltage-gated Calcium Currents In Type 4 Cone Bipolar Cells In The Mouse Retina

Qi Lu; Jin-Juan Cui; Zhuo-Hua Pan

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1163.

ARVO Annual Meeting Abstract April 2011

Sodium Channel Clustering in an AII Amacrine Cell Process Revealed By Targeting Chop2-GFP with the Ankyrin Binding Domain Motif

Chaowen Wu; Elena Ivanova; Jinjuan Cui; Zhuo-Hua Pan

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1165.

Retina October 2010

Evaluation of AAV-Mediated Expression of Chop2-GFP in the Marmoset Retina

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Elena Ivanova; Grace-Soon Hwang; Zhuo-Hua Pan; David Troilo
TAGS: callithrix, neurons, retina, mass or substance concentration per volume
Invest. Ophthalmol. Vis. Sci.. 2010; 51(10):5288-5296. https://doi.org/10.1167/iovs.10-5389

ARVO Annual Meeting Abstract April 2010

AAV-Mediated Subcellular Targeting of Chop2-GFP in Retinal Ganglion Cells

C. Wu; E. Ivanova; Y. Zhang; Z.-H. Pan

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):3298.

ARVO Annual Meeting Abstract April 2010

Cell Type-Specific Targeting of Channelrhodopsin-2 in the Retina Through AAV-Mediated Cre/LoxP Recombination in Cre-Transgenic Mouse Lines

Z.-H. Pan; E. Ivanova

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):3466.

ARVO Annual Meeting Abstract April 2009

Evaluation of AAV-Mediated Expression of Channelrhodopsin-2 in the Marmoset Retina

E. Ivanova; G.-S. Hwang; Z.-H. Pan; D. Troilo

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):1027.

ARVO Annual Meeting Abstract April 2009

Ectopic Expression of Multiple Microbial Rhodopsins Restores ON and OFF Light Responses in Retinas With Photoreceptor Degeneration

Y. Zhang; E. Ivanova; A. Bi; Z.-H. Pan

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):3894.

ARVO Annual Meeting Abstract May 2008

Expression of 1H (CaV3.2) T-Type Calcium Channels in an OFF-Type Retinal Bipolar Cell and Lack of Optokinetic Reflex With Diminished Retinal Directional Selectivity in 1H-Deficient Mice

J. Cui; E. Ivanova; H. Chen; N. Tian; Z.-H. Pan

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):1421.

ARVO Annual Meeting Abstract May 2007

Evaluation of Virus Mediated Long-Term Expression of Channelrhodopsin-2 in the Mouse Retina

E. Ivanova; A. Bi; Z.-H. Pan

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):613.

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AAV dose-dependent transduction efficiency in RGCs and functional efficacy of CoChR3M-mediated vision restoration

Targeted Expression of Retinoschisin by Retinal Bipolar Cells in XLRS Promotes Resolution of Retinoschisis Cysts Sans RS1 From Photoreceptors

Optogenetic approaches to restoring vision

Impact of retinal degeneration on restoring functional vision by optogenetics in rd mice

Retinal ganglion cell targeting is more efficient than bipolar cell targeting for optogenetic vision restoration

An ultra light-sensitive CoChR mutant restores functional vison in a blind mouse model under ambient light conditions

An unique subtype of BCs provides excitatory input to both ON and OFF synaptic pathways from both rods and cones in the retina

A Robust Optomotor Assay for Assessing the Efficacy of Optogenetic Tools for Vision Restoration

Evaluation and Optimization of A Highly Light-Sensitive Channelrhodopsin CoChR for Vision Restoration

AAV-Mediated Expression Targeting of Retinal Rod Bipolar Cells with An Optimized mGluR6 Promoter

Development and Evaluation of Highly Light-Sensitive Channelrhodopsin-2 Mutants for Vision Restoration

Characterization Of Voltage-gated Calcium Currents In Type 4 Cone Bipolar Cells In The Mouse Retina

Sodium Channel Clustering in an AII Amacrine Cell Process Revealed By Targeting Chop2-GFP with the Ankyrin Binding Domain Motif

Evaluation of AAV-Mediated Expression of Chop2-GFP in the Marmoset Retina

AAV-Mediated Subcellular Targeting of Chop2-GFP in Retinal Ganglion Cells

Cell Type-Specific Targeting of Channelrhodopsin-2 in the Retina Through AAV-Mediated Cre/LoxP Recombination in Cre-Transgenic Mouse Lines

Evaluation of AAV-Mediated Expression of Channelrhodopsin-2 in the Marmoset Retina

Ectopic Expression of Multiple Microbial Rhodopsins Restores ON and OFF Light Responses in Retinas With Photoreceptor Degeneration

Expression of 1H (CaV3.2) T-Type Calcium Channels in an OFF-Type Retinal Bipolar Cell and Lack of Optokinetic Reflex With Diminished Retinal Directional Selectivity in 1H-Deficient Mice

Evaluation of Virus Mediated Long-Term Expression of Channelrhodopsin-2 in the Mouse Retina

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