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Clinical Trials April 2025

Effect of Repeated Low-Level Red Light Versus 0.01% Topical Atropine on Myopia Progression: A Randomized Crossover-Controlled Trial

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Xuena Pang; Xuemin Jin; Aicun Fu; Weiqun Wang; Bingxin Zhao; Lili Shang; Minghang Chang; Nana Ma; Guangying Zheng
TAGS: atropine, myopia, child, red light
Trans. Vis. Sci. Tech.. 2025; 14(4):22. https://doi.org/10.1167/tvst.14.4.22

Includes: Supplemental Content

Glaucoma April 2025

Targeted Neuroprotection of Retinal Ganglion Cells Via AAV2-hSyn-NGF Gene Therapy in Glaucoma Models

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Xinlei Zhu; Benxiang Qi; Zhongmei Ren; Lin Cong; Xiaojing Pan; Qingjun Zhou; Bi Ning Zhang; Lixin Xie
TAGS: glaucoma, injections, gene therapy, neuroprotection, retinal ganglion cells, intravitreal injections
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):48. https://doi.org/10.1167/iovs.66.4.48

Includes: Supplemental Content

Cornea March 2025

A Novel Model for Cornea Power Shift in Eyes Wearing Orthokeratology Lenses With Different Back Optic Zone Diameters for Myopia Control

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Ting Wang; Xiaoqin Chen; Mengdi Li; Hua Bi; Xiaoyan Yang; Muhan Sun; Yue Liu; Lihua Li; Bin Zhang
TAGS: cornea, eye, lens (device), lens, crystalline, myopia, orthokeratology contact lenses, optics
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):29. https://doi.org/10.1167/iovs.66.3.29

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

A Study of a Color Adaptation Mechanism on Visual Performance and Ocular Health

Jin Zi-Bing; Zehua Xu; Jiaying Lei; Jinfang Wu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3085.

ARVO Annual Meeting Abstract June 2024

Single-cell RNA sequencing analysis revealed rod photoreceptors are most sensitive to age-induced degeneration

Mei Chen; Miao Tang; Bin Zou; Lia wei; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):563.

ARVO Annual Meeting Abstract June 2024

Insulin for treatment of neurotrophic ulcers: Clinical evidence and potential mechanism

Victoria Elisabeth Birgit Zeisberg; Matthias Zenkel; Andreas Gießl; Ursula Schlötzer-Schrehardt; Theofilos Tourtas; Julia M Weller; Victor A. Augustin; Friedrich E Kruse

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):56.

ARVO Annual Meeting Abstract June 2024

The myopia control effect in children wearing orthokeratology lenses with different back optical zone diameters

Ting Wang; Nicholas Green; Hua Bi; Muhan Sun; Xiaoqin Chen; Bin Zhang; Lihua Li

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2835.

Artificial Intelligence April 2024

Trends in the Prevalence of Common Retinal and Optic Nerve Diseases in China: An Artificial Intelligence Based National Screening

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Ruiheng Zhang; Li Dong; Xuefei Fu; Lin Hua; Wenda Zhou; Heyan Li; Haotian Wu; Chuyao Yu; Yitong Li; Xuhan Shi; Yangjie Ou; Bing Zhang; Bin Wang; Zhiqiang Ma; Yuan Luo; Meng Yang; Xiangang Chang; Zhaohui Wang; Wenbin Wei
TAGS: artificial intelligence, china, optic nerve disorders, prevalence, screening, trend
Trans. Vis. Sci. Tech.. 2024; 13(4):28. https://doi.org/10.1167/tvst.13.4.28

Includes: Supplemental Content

Glaucoma March 2024

The Role and Mechanism of Nicotinamide Riboside in Oxidative Damage and a Fibrosis Model of Trabecular Meshwork Cells

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Yuping Zeng; Yijun Lin; Juhua Yang; Xiaohui Wang; Yihua Zhu; Biting Zhou

Trans. Vis. Sci. Tech.. 2024; 13(3):24. https://doi.org/10.1167/tvst.13.3.24

Includes: Supplemental Content

Cornea September 2023

Extracellular Vesicle MicroRNAs From Corneal Stromal Stem Cell Enhance Stemness of Limbal Epithelial Stem Cells by Targeting the Notch Pathway

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Leying Wang; Xizhan Xu; Qiankun Chen; Yuan Wei; Zhenyu Wei; Zi-Bing Jin; Qingfeng Liang
TAGS: cornea, epithelial stem cells, extracellular vesicles, mesenchymal stem cells, micrornas, phenotype
Invest. Ophthalmol. Vis. Sci.. 2023; 64(12):42. https://doi.org/10.1167/iovs.64.12.42

Includes: Supplemental Content

Genetics September 2023

Comprehensive Genetic Analysis Unraveled the Missing Heritability and a Founder Variant of BEST1 in a Chinese Cohort With Autosomal Recessive Bestrophinopathy

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Jie Shi; Lu Tian; Tengyang Sun; Xiao Zhang; Ke Xu; Yue Xie; Xiaoyan Peng; Xin Tang; Zi-Bing Jin; Yang Li
TAGS: autosomal recessive inheritance, best1 gene, bestrophinopathy, chinese (other dialects), chinese people, cohort studies, genetic analysis, polymerase chain reaction, haplotypes
Invest. Ophthalmol. Vis. Sci.. 2023; 64(12):37. https://doi.org/10.1167/iovs.64.12.37

Includes: Supplemental Content

Artificial Intelligence June 2023

Metagenome Investigation of Ocular Microbiota of Cataract Patients With and Without Type 2 Diabetes

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Zheng Shao; Xiaona Shan; Lili Jing; Weina Wang; Wenfeng Li; Zhichao Ren; Bi Ning Zhang; Yusen Huang
TAGS: cataract, diabetes mellitus, type 2, microbiome, ocular surfaces, conjunctival sac
Trans. Vis. Sci. Tech.. 2023; 12(6):1. https://doi.org/10.1167/tvst.12.6.1

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Worldwide multicenter ocular imaging study (EyeConic) to identify patients eligible for cone-based optogenetics therapy

Lucas Janeschitz-Kriegl; Zoltán Zsolt Nagy; Boris Rosin; Jacque L Duncan; Michel Michaelides; Byron L Lam; Samer Khateb; Katarina Stingl; Kaoru Fujinami; Giacomo Calzetti; Zi-Bing Jin; Karsten Borgwardt; Michael Adamer; Botond Roska; Bence Gyorgy; Hendrik P Scholl

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5517.

ARVO Annual Meeting Abstract June 2023

Postnatal eye size in mice is controlled by SREBP2-mediated transcriptional repression of Lrp2 and Bmp2

MAI SHUYI; Xiaoxuan Zhu; Esther Yi Ching Wan; Shengyu Wu; Jesslyn Nagalin Yonathan; Jun Wang; Ying Li; Jessica Yuen Wuen Ma; Bing Zuo; Dennis Yan-yin Tse; Pui-Chi Lo; Xin Wang; Kui Ming Chan; David M Wu; Wenjun Xiong

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):960.

ARVO Annual Meeting Abstract June 2023

Fuchs endothelial corneal dystrophy and epithelial basement membrane dystrophy - DMEK alone or combined with debridement of the corneal epithelium?

Victoria Elisabeth Birgit Zeisberg; Julia M. Weller; Theofilos Tourtas; Friedrich E. Kruse

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4792.

ARVO Annual Meeting Abstract June 2023

Associations of retinal layer thicknesses and regional brain volumes in UK Biobank

Zihan Sun; Bing Zhang; Robert Luben; Kelsey Vernon Stuart; Mahantesh Biradar; Tom MacGillivray; Praveen J Patel; Naomi Allen; Denize Atan; Peng Tee Khaw; Stephen Smith; Anthony Khawaja; Axel Petzold; Paul Foster

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1755.

ARVO Annual Meeting Abstract June 2023

Retinal mitochondrial dysfunction and neurodegeneration in a mouse model of type 2 diabetes mellites

Christie Hang-i Lam; Bing Zuo; Dennis Yan-yin Tse

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3899.

ARVO Annual Meeting Abstract June 2023

Quantifying the morphology of eyeballs with posterior staphyloma with Zernike polynomials

Hua Rong; Bin Zhang; Ruihua Wei

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4160.

Cornea May 2023

Norepinephrine as the Intrinsic Contributor to Contact Lens–Induced Pseudomonas aeruginosa Keratitis

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Bi Ning Zhang; Benxiang Qi; Wai Kit Chu; Fangying Song; Suxia Li; Qiaoqiao Dong; Zheng Shao; Bin Zhang; Xianli Du; Xiubin Ma; Vishal Jhanji; Qingjun Zhou
TAGS: adrb2 gene, beta-2 adrenergic receptors, contact lenses, cornea, infections, keratitis, mice, norepinephrine, pseudomonas aeruginosa, epithelium
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):26. https://doi.org/10.1167/iovs.64.5.26

Includes: Supplemental Content

Lens May 2023

MicroRNA-22-3p Regulates the Apoptosis of Lens Epithelial Cells Through Targeting KLF6 in Diabetic Cataracts

PDF

Xin Yin; Ling Chen; Jiachao Shen; Zhaojing Bi; Chen Chen; Xinmei Zhao; Shujun Liu; Yuanbin Li
TAGS: apoptosis, diabetic cataract, kruppel-like factor 6, lens epithelial cell, micrornas, glucose
Trans. Vis. Sci. Tech.. 2023; 12(5):9. https://doi.org/10.1167/tvst.12.5.9

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Effect of Repeated Low-Level Red Light Versus 0.01% Topical Atropine on Myopia Progression: A Randomized Crossover-Controlled Trial

Targeted Neuroprotection of Retinal Ganglion Cells Via AAV2-hSyn-NGF Gene Therapy in Glaucoma Models

A Novel Model for Cornea Power Shift in Eyes Wearing Orthokeratology Lenses With Different Back Optic Zone Diameters for Myopia Control

A Study of a Color Adaptation Mechanism on Visual Performance and Ocular Health

Single-cell RNA sequencing analysis revealed rod photoreceptors are most sensitive to age-induced degeneration

Insulin for treatment of neurotrophic ulcers: Clinical evidence and potential mechanism

The myopia control effect in children wearing orthokeratology lenses with different back optical zone diameters

Trends in the Prevalence of Common Retinal and Optic Nerve Diseases in China: An Artificial Intelligence Based National Screening

The Role and Mechanism of Nicotinamide Riboside in Oxidative Damage and a Fibrosis Model of Trabecular Meshwork Cells

Extracellular Vesicle MicroRNAs From Corneal Stromal Stem Cell Enhance Stemness of Limbal Epithelial Stem Cells by Targeting the Notch Pathway

Comprehensive Genetic Analysis Unraveled the Missing Heritability and a Founder Variant of BEST1 in a Chinese Cohort With Autosomal Recessive Bestrophinopathy

Metagenome Investigation of Ocular Microbiota of Cataract Patients With and Without Type 2 Diabetes

Worldwide multicenter ocular imaging study (EyeConic) to identify patients eligible for cone-based optogenetics therapy

Postnatal eye size in mice is controlled by SREBP2-mediated transcriptional repression of Lrp2 and Bmp2

Fuchs endothelial corneal dystrophy and epithelial basement membrane dystrophy - DMEK alone or combined with debridement of the corneal epithelium?

Associations of retinal layer thicknesses and regional brain volumes in UK Biobank

Retinal mitochondrial dysfunction and neurodegeneration in a mouse model of type 2 diabetes mellites

Quantifying the morphology of eyeballs with posterior staphyloma with Zernike polynomials

Norepinephrine as the Intrinsic Contributor to Contact Lens–Induced Pseudomonas aeruginosa Keratitis

MicroRNA-22-3p Regulates the Apoptosis of Lens Epithelial Cells Through Targeting KLF6 in Diabetic Cataracts

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