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Artificial Intelligence June 2025

Development of Deep Learning Models to Screen Posterior Staphylomas in Highly Myopic Eyes Using UWF-OCT Images

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Yining Wang; Changyu Chen; Ziye Wang; Yijin Wu; Hongshuang Lu; Jianping Xiong; Keigo Sugisawa; Koju Kamoi; Kyoko Ohno-Matsui
TAGS: datasets, deep learning, eye, staphyloma, retina, specialism
Trans. Vis. Sci. Tech.. 2025; 14(6):25. https://doi.org/10.1167/tvst.14.6.25

Includes: Supplemental Content

Article June 2025

The latent mechanism behind binocular advantage in reading

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Zhenyu Zhang; Tingting Wang; Zile Wang; Jinmei Xiao; Qingshang Ma; Xianyuan Yang; Fang-Fang Yan; Chang-Bing Huang
TAGS: reading (activity), ocular dominance, saccades
Journal of Vision. 2025; 25(7):6. https://doi.org/10.1167/jov.25.7.6

Lens May 2025

Identification of Age- and Cataract-Related Changes in High-Density Lens Protein Aggregates

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Zhen Wang; Michael G. Friedrich; Roger J. W. Truscott; Kevin L. Schey
TAGS: cataract, crystallins, lens (device), lens, crystalline, proteins, peptides
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):34. https://doi.org/10.1167/iovs.66.5.34

Includes: Supplemental Content

Cornea April 2025

Pax6 Directly Regulates the Raver2/sFlt-1 Expression in Corneal Epithelial Cells to Maintain the Cornea's Avascular Privilege

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Haiqi Xiao; Li Hu; Xiongshi Lin; Linchang Liu; Xing Dong; Liting Yang; Ying Liu; Zhichong Wang; Ying Tian; Shuangyong Wang
TAGS: pax6 transcription factor, soluble fms-like tyrosine kinase 1
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):52. https://doi.org/10.1167/iovs.66.4.52

Includes: Supplemental Content

Retina April 2025

Nicotinamide Riboside Mitigates Retinal Degeneration by Suppressing Damaged DNA-Stimulated Microglial Activation and STING-Mediated Pyroptosis

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Shanshan Zhu; Lusi Zhang; Ping Tong; Jiawei Chen; Cong Wang; Zewei Wang; Jingyuan Liu; Peiyun Duan; Qian Jiang; Yubing Zhou; Guangshuang Tan; Xian Zhang; Bing Jiang
TAGS: dna, niacinamide, pyroptosis, retinal degeneration, retina, light exposure, mice, neuroinflammatory diseases, photoreceptors, microglia
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):14. https://doi.org/10.1167/iovs.66.4.14

Includes: Supplemental Content

Anatomy and Pathology/Oncology March 2025

Whorl-Like Collagen Fiber Arrangement Around Emissary Canals in the Posterior Sclera

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Hongshuang Lu; Yijin Wu; Jianping Xiong; Nan Zhou; Masahiro Yamanari; Michiaki Okamoto; Keigo Sugisawa; Hiroyuki Takahashi; Changyu Chen; Yining Wang; Ziye Wang; Kyoko Ohno-Matsui
TAGS: collagen fiber, eye, sclera
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):35. https://doi.org/10.1167/iovs.66.3.35

Includes: Multimedia, Supplemental Content

Cornea February 2025

Identification of Wnt-5a Receptors Important in Diabetic and Non-Diabetic Corneal Epithelial Wound Healing

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Ruchi Shah; Cynthia Amador; Adam J. Poe; Tanya M. Spektor; Priyanka Bhandary; Yizhou Wang; Zhiping Paul Wang; Daniel J. Weisenberger; Vanessa F. Borges; Onkar B. Sawant; Ezra Maguen; Pedram Hamrah; Andrei A. Kramerov; Mehrnoosh Saghizadeh; Alexander V. Ljubimov
TAGS: cornea, diabetes mellitus, receptors, wnt, wnt-5a protein, wound healing, epithelium, receptor tyrosine kinase-like orphan receptor 2
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):64. https://doi.org/10.1167/iovs.66.2.64

Includes: Supplemental Content

Immunology and Microbiology February 2025

kexB Gene Correlates With Aspergillus flavus Keratitis Severity: A Whole-Genome Analysis

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Jiamin Liu; Min Kang; Yuan Wei; Zijun Zhang; Jinding Pang; Qiankun Chen; Xizhan Xu; Zhenyu Wei; Yang Zhang; Kexin Chen; Zhiqun Wang; Xinxin Lu; Qingfeng Liang
TAGS: genes, genome, keratitis, virulence, aspergillus flavus, cornea, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):42. https://doi.org/10.1167/iovs.66.2.42

Includes: Supplemental Content

Cornea & External Disease January 2025

Clinical Characteristics and In Vivo Confocal Microscopic Study in Candida Keratitis

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Yan Peng; Qiankun Chen; Yuan Wei; Leying Wang; Zijun Zhang; Zhenyu Wei; Jinding Pang; Bo Peng; Qingquan Shi; Zhiqun Wang; Yang Zhang; Kexin Chen; Xizhan Xu; Qingfeng Liang
TAGS: candida, keratitis, hyphae, plant spores, reproduction spores
Trans. Vis. Sci. Tech.. 2025; 14(1):23. https://doi.org/10.1167/tvst.14.1.23

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology January 2025

Fixation Stability Deficits in Anisometropic Amblyopia

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Yusong Zhou; Wentong Yu; Qingqing Ye; Zixuan Xu; Yunsi He; Ying Yao; Yangfei Pang; Yudan Zhong; Qiuying Li; Lei Feng; Yun Wen; Xuan Qiu; Zhonghao Wang; Jinrong Li
TAGS: amblyopia, anisometropic amblyopia, eye, vision, contrast sensitivity, visual acuity
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):14. https://doi.org/10.1167/iovs.66.1.14

Includes: Supplemental Content

Retina January 2025

Blue Light Damages Retinal Ganglion Cells Via Endoplasmic Reticulum Stress and Autophagy in Chickens

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Deng Pan; Ge Hu; Jiayue Li; Zixu Wang; Yaoxing Chen; Jing Cao
TAGS: autophagy, chickens, stress, retina, blue light, endoplasmic reticulum, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):3. https://doi.org/10.1167/iovs.66.1.3

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2024

Exploring the Relationship Between Refractive Errors and Common Chronic Diseases Via Blood Biochemistry Tests: A Large Prospective Cohort Study

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Yanze Yu; Hao Chen; Zhanying Wang; Yuhao Ye; Zhe Zhang; Yongle Bao; Yingnan Jia; Xingtao Zhou; Jing Zhao
TAGS: biochemistry, chronic disease, diabetes mellitus, type 2, myopia, prospective studies, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):26. https://doi.org/10.1167/iovs.65.13.26

Includes: Supplemental Content

Visual Neuroscience November 2024

Overcoming Low mRNA Expression in White Matter: A Protocol for RNA Extraction From the Optic Nerve in Large Animals for Transcriptomic Analysis

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Zhonghao Yu; Yue Guan; Tian Xia; Xuanwen Li; Mingyue Liu; Yujia Huo; Zhuowei Wang; Zhirong Liu; Yuting Luo; Wentao Yan; Lanfang Sun; Wencan Wu; Baoguo Shen; Yikui Zhang
TAGS: optic nerve, rna, rna, messenger, white matter
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):25. https://doi.org/10.1167/iovs.65.13.25

Includes: Multimedia, Supplemental Content

Pediatric Ophthalmology & Strabismus October 2024

Use of a Microelectromechanical Systems Sensor for Objective Measurements of Abnormal Head Posture in Congenital Superior Oblique Palsy Patients

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Xuan Qiu; Zhonghao Wang; Liuqing Pan; Tao Shen; Daming Deng; Qiwen Chen; Jianhua Yan
TAGS: fourth cranial nerve palsy, posture, sensor, standard operating procedure, head position
Trans. Vis. Sci. Tech.. 2024; 13(10):30. https://doi.org/10.1167/tvst.13.10.30

Includes: Supplemental Content

Visual Neuroscience September 2024

Delayed Surgical Reversal of Optic Nerve Compression Leads to Exponential Degeneration of Optic Nerve Fibers and Selective Sparing of the Small Fibers

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XiaoHui Jiang; Boyue Xu; Shuang Yao; Zhuowei Wang; Mingyue Liu; Yikui Zhang; Wencan Wu; Ende Wu
TAGS: axon, decompression, external, decompressive incision, optic nerve, optic nerve compression, optic nerve decompression, surgical procedures, operative, tissue degeneration, survival, apoptosis
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):40. https://doi.org/10.1167/iovs.65.11.40

Vision Sciences Society Annual Meeting Abstract September 2024

Attentional template activation and switch costs during preparation for predictable multiple-colour search

Ziyi Wang; Martin Eimer; Anna Grubert1

Journal of Vision. 2024; 24(10):820. https://doi.org/10.1167/jov.24.10.820

Vision Sciences Society Annual Meeting Abstract September 2024

Temporal dynamics of multiple attentional template activation during preparation for search

Anna Grubert; Ziyi Wang; Mikel Jimenez; Ella Wiliams; Roger Remington; Martin Eimer

Journal of Vision. 2024; 24(10):283. https://doi.org/10.1167/jov.24.10.283

Vision Sciences Society Annual Meeting Abstract September 2024

The effect of attentional load on modal and amodal completion

Zeyu Wang; Jinyou Zou; Peng Zhang

Journal of Vision. 2024; 24(10):921. https://doi.org/10.1167/jov.24.10.921

Vision Sciences Society Annual Meeting Abstract September 2024

Association between Proficiency and Idiosyncratic Biases in Medical Image Perception

Zhihang Ren; Julien Vignoud; Zixuan Wang; Heath Rutledge-Jukes; Tejas C. Sekhar; Kathy Fang; Erik P. Duhaime; David Whitney

Journal of Vision. 2024; 24(10):1155. https://doi.org/10.1167/jov.24.10.1155

Vision Sciences Society Annual Meeting Abstract September 2024

Oculomotor influences on extrafoveal sensitivity

Jie Z. Wang; Michele Rucci

Journal of Vision. 2024; 24(10):334. https://doi.org/10.1167/jov.24.10.334

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Development of Deep Learning Models to Screen Posterior Staphylomas in Highly Myopic Eyes Using UWF-OCT Images

The latent mechanism behind binocular advantage in reading

Identification of Age- and Cataract-Related Changes in High-Density Lens Protein Aggregates

Pax6 Directly Regulates the Raver2/sFlt-1 Expression in Corneal Epithelial Cells to Maintain the Cornea's Avascular Privilege

Nicotinamide Riboside Mitigates Retinal Degeneration by Suppressing Damaged DNA-Stimulated Microglial Activation and STING-Mediated Pyroptosis

Whorl-Like Collagen Fiber Arrangement Around Emissary Canals in the Posterior Sclera

Identification of Wnt-5a Receptors Important in Diabetic and Non-Diabetic Corneal Epithelial Wound Healing

kexB Gene Correlates With Aspergillus flavus Keratitis Severity: A Whole-Genome Analysis

Clinical Characteristics and In Vivo Confocal Microscopic Study in Candida Keratitis

Fixation Stability Deficits in Anisometropic Amblyopia

Blue Light Damages Retinal Ganglion Cells Via Endoplasmic Reticulum Stress and Autophagy in Chickens

Exploring the Relationship Between Refractive Errors and Common Chronic Diseases Via Blood Biochemistry Tests: A Large Prospective Cohort Study

Overcoming Low mRNA Expression in White Matter: A Protocol for RNA Extraction From the Optic Nerve in Large Animals for Transcriptomic Analysis

Use of a Microelectromechanical Systems Sensor for Objective Measurements of Abnormal Head Posture in Congenital Superior Oblique Palsy Patients

Delayed Surgical Reversal of Optic Nerve Compression Leads to Exponential Degeneration of Optic Nerve Fibers and Selective Sparing of the Small Fibers

Attentional template activation and switch costs during preparation for predictable multiple-colour search

Temporal dynamics of multiple attentional template activation during preparation for search

The effect of attentional load on modal and amodal completion

Association between Proficiency and Idiosyncratic Biases in Medical Image Perception

Oculomotor influences on extrafoveal sensitivity

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