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Meeting Abstract (11)
Journal Articles (3)

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Investigative Ophthalmology & Visual Science (14)

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ARVO Annual Meeting Abstract (11)
Visual Neuroscience (2)
Multidisciplinary Ophthalmic Imaging (1)

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Eye Anatomy and Disorders (3)
Visual Neuroscience (2)
Multidisciplinary Ophthalmic Imaging (1)
Retina (1)
Surgery (1)

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optic nerve (2)
tissue degeneration (2)
apoptosis (1)
axon (1)
compression (1)
dark adaptation (1)
decompression, external (1)
decompressive incision (1)
eye (1)
mice (1)

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Showing 1 – 14 of 14

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ARVO Annual Meeting Abstract June 2025

Multi-Species Single-Nuclear Analysis Reveals Species Heterogeneity in the Optic Nerve

xuanwen Li; Zhang Yikui; Zhonghao Yu; Yue Guan; Wencan Wu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1322.

ARVO Annual Meeting Abstract June 2025

Optic Nerve Protection Through Surgical Intervention at the Optic Canal

Zhang Yikui; Zhonghao Yu; Tian Xia; Wencan Wu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3447.

Visual Neuroscience November 2024

Overcoming Low mRNA Expression in White Matter: A Protocol for RNA Extraction From the Optic Nerve in Large Animals for Transcriptomic Analysis

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Zhonghao Yu; Yue Guan; Tian Xia; Xuanwen Li; Mingyue Liu; Yujia Huo; Zhuowei Wang; Zhirong Liu; Yuting Luo; Wentao Yan; Lanfang Sun; Wencan Wu; Baoguo Shen; Yikui Zhang
TAGS: optic nerve, rna, rna, messenger, white matter
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):25. https://doi.org/10.1167/iovs.65.13.25

Includes: Multimedia, Supplemental Content

Visual Neuroscience September 2024

Delayed Surgical Reversal of Optic Nerve Compression Leads to Exponential Degeneration of Optic Nerve Fibers and Selective Sparing of the Small Fibers

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XiaoHui Jiang; Boyue Xu; Shuang Yao; Zhuowei Wang; Mingyue Liu; Yikui Zhang; Wencan Wu; Ende Wu
TAGS: axon, decompression, external, decompressive incision, optic nerve, optic nerve compression, optic nerve decompression, surgical procedures, operative, tissue degeneration, survival, apoptosis
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):40. https://doi.org/10.1167/iovs.65.11.40

ARVO Annual Meeting Abstract June 2024

Optimized RNA isolation procedure for multi-transcriptomic techniques analysis of low mRNA-expressing optic nerve in large animals

Zhonghao Yu; Zhang Yikui; Wencan Wu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2460.

ARVO Annual Meeting Abstract June 2024

sn-seq & spatial-seq in a clinically-resembling model of optic nerve concussion reveals white matter protection strategies

Zhang Yikui; Zhonghao Yu; Shengjian Lu; Wencan Wu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3327.

ARVO Annual Meeting Abstract June 2024

A portal skull-base brain machine interface for real-time monitoring of optic nerve activity

Shengjian Lu; Zhang Yikui; Wencan Wu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2457.

ARVO Annual Meeting Abstract June 2020

In vivo e valuation of optic nerve’s function and structure in large animals by multi-modality analysis

Yu Xia; Si Zhang; Yuanfei Ji; Mengyun Li; Yikui Zhang; Wencan Wu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4583.

ARVO Annual Meeting Abstract June 2020

A novel clinically-relevant optic nerve injury model in goats and rhesus macaques by surgical exposure of optic canal in a safe and effective way

Yikui Zhang; Senmiao Zhu; Bo yu; Hui Zhu; Pingping Huang; Wenhao Jiang; Yu Xia; Mengyun Li; Wencan Wu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4584.

Multidisciplinary Ophthalmic Imaging February 2018

Light-Dependent OCT Structure Changes in Photoreceptor Degenerative rd 10 Mouse Retina

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Yichao Li; Yikui Zhang; Sonia Chen; Gregory Vernon; Wai T. Wong; Haohua Qian
TAGS: mice, photoreceptors, retina, dark adaptation, eye, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):1084-1094. https://doi.org/10.1167/iovs.17-23011

ARVO Annual Meeting Abstract June 2017

Microglia homeostasis in the adult mouse retina: restoration of microglial distribution, morphology, and function following acute depletion

Yikui Zhang; Lian Zhao; Xu Wang; Wenxin Ma; Adam Lazere; Haohua Qian; Robert N Fariss; Jun Zhang; Mones S Abu-Asab; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):806.

ARVO Annual Meeting Abstract June 2017

Tamoxifen provides structural and functional rescue in murine models of photoreceptor degeneration

Xu Wang; Lian Zhao; Wenxin Ma; Yikui Zhang; Shaimar Gonzalez; Jianguo Fan; Friedrich Kretschmer; Tudor C Badea; Haohua Qian; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5901.

ARVO Annual Meeting Abstract September 2016

CX3CR1 deficiency affects microglial phagocytosis in rd10 retinal degeneration

Lian Zhao; Matthew Zabel; Yikui Zhang; Shaimar Gonzalez; Wenxin Ma; Xu Wang; Robert N Fariss; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2267.

ARVO Annual Meeting Abstract September 2016

Repopulation of the retina by myeloid cells following depletion of endogenous retinal microglia in adult mice

Yikui Zhang; Lian Zhao; Xu Wang; Robert N Fariss; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4185.

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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