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Retinal Cell Biology January 2025

Inhibition of Retinal Neovascularization by BEZ235: Targeting the Akt/4EBP1/Cyclin D1 Pathway in Endothelial Cells

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Qi Liu; Ling-Xiao Xia; Wan-Zhao Yi; Ya-Ni Wu; Shuo-Shuo Gu; Jian-Ying Chen; Ting-Ting Liu; Ying-Hui Lu; Yu-Hong Cui; Jing Meng; Hong-Wei Pan
TAGS: cyclin d1, endothelial cells, proto-oncogene proteins c-akt, retinal neovascularization, cell cycle, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):66. https://doi.org/10.1167/iovs.66.1.66

Includes: Supplemental Content

Glaucoma October 2024

Low Intraocular Pressure Induces Fibrotic Changes in the Trabecular Meshwork and Schlemm's Canal of Sprague Dawley Rats

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Lijuan Xu; Yin Zhao; Xinyao Zhang; Xiaorui Gang; Jialing Han; Tao Zhou; Binyan Qi; Shuning Song; Ruiyi Ren; Yuanbo Liang
TAGS: intraocular pressure, rats, fibrosis, eye, schlemm's canal, trabecular meshwork
Trans. Vis. Sci. Tech.. 2024; 13(10):10. https://doi.org/10.1167/tvst.13.10.10

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology July 2024

Association of Retinal Biomarkers With the Subtypes of Ischemic Stroke and an Automated Classification Model

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Zhouwei Xiong; William R. Kwapong; Shouyue Liu; Tao Chen; Keyi Xu; Haiting Mao; Jinkui Hao; Le Cao; Jiang Liu; Yalin Zheng; Hang Wang; Yuying Yan; Chen Ye; Bo Wu; Hong Qi; Yitian Zhao
TAGS: ischemic stroke, biological markers
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):50. https://doi.org/10.1167/iovs.65.8.50

ARVO Annual Meeting Abstract June 2024

AIV007 Is a Potent Anti-angiogenic Agent with Anti-fibrotic Effect

Yi Zhao; Gerald W De Vries; Diane DS Tang-Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1946.

ARVO Annual Meeting Abstract June 2024

Assessing the effectiveness and feasibility of a community-based ocular screening model for the elderly in China: the Wenzhou Eye Study

GU ZHENG; Shiqi Hu; Yiming Zhao; Xinmin Wang; Yanyan Lin; Tianhao Huang; Shilei Wang; Cong Ye; Fan Lu; Xinting Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):614.

Biochemistry and Molecular Biology February 2024

Deficiency of Acetyltransferase nat10 in Zebrafish Causes Developmental Defects in the Visual Function

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Hou-Zhi Yang; Donghai Zhuo; Zongyu Huang; Gan Luo; Shuang Liang; Yonggang Fan; Ying Zhao; Xinxin Lv; Caizhen Qiu; Lingzhu Zhang; Yang Liu; Tianwei Sun; Xu Chen; Shan-Shan Li; Xin Jin
TAGS: zebrafish, congenital abnormality, vision, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):31. https://doi.org/10.1167/iovs.65.2.31

Clinical and Epidemiologic Research October 2023

Unsupervised Learning Based on Meibography Enables Subtyping of Dry Eye Disease and Reveals Ocular Surface Features

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Siyan Li; Yiyi Wang; Chunyu Yu; Qiyuan Li; Pingjun Chang; Dandan Wang; Zhangliang Li; Yinying Zhao; Hongfang Zhang; Ning Tang; Weichen Guan; Yana Fu; Yun-e Zhao
TAGS: dry eye syndromes, learning, ocular surfaces
Invest. Ophthalmol. Vis. Sci.. 2023; 64(13):43. https://doi.org/10.1167/iovs.64.13.43

Includes: Supplemental Content

Glaucoma July 2023

TBK1 Knockdown Alleviates Axonal Transport Deficits in Retinal Ganglion Cells Via mTORC1 Activation in a Retinal Damage Mouse Model

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Meng Ye; Yuanyuan Hu; Bowen Zhao; Qianxue Mou; Yueqi Ni; Jing Luo; Lu Li; Hong Zhang; Yin Zhao
TAGS: axonal transport, mechanistic target of rapamycin complex 1, mice, raptors, retinal ganglion cells, proteins, ubiquitination, phosphorylation, glaucoma, catabolism
Invest. Ophthalmol. Vis. Sci.. 2023; 64(10):1. https://doi.org/10.1167/iovs.64.10.1

Includes: Supplemental Content

Retina June 2023

Detection of Choroidal Neovascularization Using Optical Tissue Transparency

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Xiao-Hong Ma; Wen-Yang Feng; Ke Xiao; Zheng Zhong; Peng Fei; Yin Zhao; Xu-Fang Sun
TAGS: body tissue, choroidal neovascularization, optics, transparency, lasers, fluorescent antibody technique, eye
Trans. Vis. Sci. Tech.. 2023; 12(6):10. https://doi.org/10.1167/tvst.12.6.10

Includes: Multimedia, Supplemental Content

Retina June 2023

Low-Dose Trans -Resveratrol Ameliorates Diabetes-Induced Retinal Ganglion Cell Degeneration via TyrRS/c-Jun Pathway

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Ke Xiao; Xiao-Hong Ma; Zheng Zhong; Yin Zhao; Xu-Hui Chen; Xu-Fang Sun
TAGS: diabetes mellitus, ganglia, resveratrol, retinal ganglion cells, tissue degeneration, western blotting, nuclear translocation, apoptosis, phosphorylation
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):2. https://doi.org/10.1167/iovs.64.7.2

Includes: Supplemental Content

Artificial Intelligence October 2022

Characterization of the Retinal Microvasculature and FAZ Changes in Ischemic Stroke and Its Different Types

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Hongyu Duan; Jianyang Xie; Yifan Zhou; Hui Zhang; Yiyun Liu; Chuhao Tang; Yitian Zhao; Hong Qi
TAGS: ischemic stroke, retinal vasculature
Trans. Vis. Sci. Tech.. 2022; 11(10):21. https://doi.org/10.1167/tvst.11.10.21

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

ROLE OF CHROMATIN AND DNA METHYLATION IN MOUSE LENS DIFFERENTIATION

Ales Cvekl; William Chang; Yilin Zhao; Qing Xie; Masako Suzuki; Deyou Zheng

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):837.

Retina March 2022

LECT2 Ameliorates Blood–Retinal Barrier Impairment Secondary to Diabetes Via Activation of the Tie2/Akt/mTOR Signaling Pathway

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Yuan-Jun Qin; Ke Xiao; Zheng Zhong; Yin Zhao; Tian Yu; Xu-Fang Sun
TAGS: diabetes mellitus, diabetes mellitus, type 2, mtor signaling pathway, proto-oncogene proteins c-akt, retina, hyperglycemia, blood-retinal barrier, impairment, proteins, cadherins
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):7. https://doi.org/10.1167/iovs.63.3.7

Includes: Supplemental Content

Articles November 2021

Indocyanine Green Reduces the Viability of Human Lens Epithelial Cells and Promotes Cytolysis: An Ex Vivo Study

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Zi-Fang He; Ying-Di Zhao; Si Zhang; Fei-Fei Chen; Ya-Jun Liu; Wen-Wen Zhang; Zheng-Gao Xie
TAGS: cytolysis, epithelial cells, immersion, indocyanine green, lens, crystalline, microscopes, pharmacotherapy, mass or substance concentration per volume
Trans. Vis. Sci. Tech.. 2021; 10(13):30. https://doi.org/10.1167/tvst.10.13.30

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

An Aflibercept-derived Mini-VEGF-Trap as a Potential Next-Generation VEGF Inhibitor

Raymond Wilson Leidich; Krunal Patel; Ashique Rafique; Annabel Romero Hernandez; Matthew Franklin; Miguel Lazo; Aynur Hermann; Gitanjali Sharma; Yiming Zhao; Hunter Chen; Nina Liu; Michael Rosconi; Carmelo Romano; William Olson; Neil Stahl

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):204.

ARVO Annual Meeting Abstract June 2021

Quantification of Increased Corneal Subbasal Nerve Tortuosity in Dry Eye Disease and Its Correlation with Clinical Parameters

Hong Qi; Baikai Ma; jianyang xie; Tingting Yang; Rongjun Liu; Yifan Zhou; Yitian Zhao

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1233.

ARVO Annual Meeting Abstract June 2021

Objective analysis of corneal subbasal nerve tortuosity and its changes in patients with dry eye disease and diabetes

Baikai Ma; jianyang xie; Tingting Yang; Rongjun Liu; Yiyun(Jessie) Liu; Tong Sun; Yitian Zhao; Hong Qi

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1217.

Articles May 2021

Quantification of Increased Corneal Subbasal Nerve Tortuosity in Dry Eye Disease and Its Correlation With Clinical Parameters

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Baikai Ma; Jianyang Xie; Tingting Yang; Pan Su; Rongjun Liu; Tong Sun; Yifan Zhou; Haiwei Wang; Xue Feng; Siyi Ma; Yitian Zhao; Hong Qi
TAGS: cornea, dry eye syndromes, neurons
Trans. Vis. Sci. Tech.. 2021; 10(6):26. https://doi.org/10.1167/tvst.10.6.26

Includes: Supplemental Content

Retina December 2020

Immunosubunit β5i Knockout Suppresses Neovascularization and Restores Autophagy in Retinal Neovascularization by Targeting ATG5 for Degradation

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Liyang Ji; Li Li; Ying Zhao; Shengqiang Liu; Jingmin Li; Jinsong Zhang; Qi Zhao; Shuai Wang

Invest. Ophthalmol. Vis. Sci.. 2020; 61(14):30. https://doi.org/10.1167/iovs.61.14.30

Includes: Supplemental Content

Vision Sciences Society Annual Meeting Abstract October 2020

Deep Convolutional Neural Networks for Predicting Head Pose During Brain MRI Acquisition

Yijun Zhao; Hui Yuan; Jingjie Zhou; Samantha Martin; Heath Pardoe

Journal of Vision. 2020; 20(11):817. https://doi.org/10.1167/jov.20.11.817

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Inhibition of Retinal Neovascularization by BEZ235: Targeting the Akt/4EBP1/Cyclin D1 Pathway in Endothelial Cells

Low Intraocular Pressure Induces Fibrotic Changes in the Trabecular Meshwork and Schlemm's Canal of Sprague Dawley Rats

Association of Retinal Biomarkers With the Subtypes of Ischemic Stroke and an Automated Classification Model

AIV007 Is a Potent Anti-angiogenic Agent with Anti-fibrotic Effect

Assessing the effectiveness and feasibility of a community-based ocular screening model for the elderly in China: the Wenzhou Eye Study

Deficiency of Acetyltransferase nat10 in Zebrafish Causes Developmental Defects in the Visual Function

Unsupervised Learning Based on Meibography Enables Subtyping of Dry Eye Disease and Reveals Ocular Surface Features

TBK1 Knockdown Alleviates Axonal Transport Deficits in Retinal Ganglion Cells Via mTORC1 Activation in a Retinal Damage Mouse Model

Detection of Choroidal Neovascularization Using Optical Tissue Transparency

Low-Dose Trans -Resveratrol Ameliorates Diabetes-Induced Retinal Ganglion Cell Degeneration via TyrRS/c-Jun Pathway

Characterization of the Retinal Microvasculature and FAZ Changes in Ischemic Stroke and Its Different Types

ROLE OF CHROMATIN AND DNA METHYLATION IN MOUSE LENS DIFFERENTIATION

LECT2 Ameliorates Blood–Retinal Barrier Impairment Secondary to Diabetes Via Activation of the Tie2/Akt/mTOR Signaling Pathway

Indocyanine Green Reduces the Viability of Human Lens Epithelial Cells and Promotes Cytolysis: An Ex Vivo Study

An Aflibercept-derived Mini-VEGF-Trap as a Potential Next-Generation VEGF Inhibitor

Quantification of Increased Corneal Subbasal Nerve Tortuosity in Dry Eye Disease and Its Correlation with Clinical Parameters

Objective analysis of corneal subbasal nerve tortuosity and its changes in patients with dry eye disease and diabetes

Quantification of Increased Corneal Subbasal Nerve Tortuosity in Dry Eye Disease and Its Correlation With Clinical Parameters

Immunosubunit β5i Knockout Suppresses Neovascularization and Restores Autophagy in Retinal Neovascularization by Targeting ATG5 for Degradation

Deep Convolutional Neural Networks for Predicting Head Pose During Brain MRI Acquisition

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