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ARVO Annual Meeting Abstract June 2025

Translating nascent Geographic Atrophy definition into measurable biomarkers in OCT

Alicja Krzeminska-Sciga; Zhichao Wu; Joseph Blair; Romina M Lasagni Vitar; Robyn H Guymer; Carlos Ciller; Stefanos Apostolopoulos; Sandro De Zanet

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3491.

ARVO Annual Meeting Abstract June 2025

Comprehensive Evaluation of OCT Biomarkers in Intermediate Age-Related Macular Degeneration for Predicting Disease Progression

Ye He; Alireza Mahmoudi; Muneeswar G. Nittala; Swetha Bindu Velaga; Robyn H Guymer; SriniVas R Sadda; Zhichao Wu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3622.

ARVO Annual Meeting Abstract June 2025

Customized evaluation of progressive visual sensitivity loss in geographic atrophy to improve the power of clinical trials

Zhichao Wu; Abera Saeed; Xavier Hadoux; Maxime Jannaud; Darvy Dang; Lauren A. B. Hodgson; Emily K. Glover; Erin E Gee; Peter van Wijngaarden; Robyn H Guymer

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):674.

ARVO Annual Meeting Abstract June 2025

Detecting Nascent Geographic Atrophy and Large Choroidal Signal Hypertransmission on OCT using Deep Learning

John Strand; Yelena Bagdasarova; Erin E Gee; Robyn H Guymer; Aaron Y Lee; Zhichao Wu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):560.

ARVO Annual Meeting Abstract June 2025

Predicting Visual Sensitivity Loss in Eyes with Geographic Atrophy using OCT Imaging and Fundus Autofluorescence

Joseph Blair; Robyn H Guymer; Sandro De Zanet; Zhichao Wu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2793.

ARVO Annual Meeting Abstract June 2025

Targeted Defect-Mapping Microperimetry in Geographic Atrophy – A Sensitive Functional Outcome Measure for Intervention Trials

Abera Saeed; Robyn H Guymer; Xavier Hadoux; Maxime Jannaud; Darvy Dang; Lauren A. B. Hodgson; Emily K. Glover; Erin E Gee; Peter van Wijngaarden; Zhichao Wu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4133.

ARVO Annual Meeting Abstract June 2025

The chromosome 10 rs11200638 polymorphism, reticular pseudodrusen and rod-mediated dark adaptation

Carla J Abbott; Samaneh Farashi; Zhichao Wu; Brendan Robert E Ansell; Alice Pebay; Erica L Fletcher; Melanie Bahlo; Robyn H Guymer

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4103.

Retina December 2024

Longitudinal Changes of Visual Sensitivity With Geographic Atrophy Progression Assessed by Defect-Mapping Microperimetry

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Abera Saeed; Robyn H. Guymer; Xavier Hadoux; Maxime Jannaud; Darvy Dang; Lauren A. B. Hodgson; Emily K. Glover; Erin E. Gee; Peter van Wijngaarden; Zhichao Wu
TAGS: age-related macular degeneration, nonexudative, fundus autofluorescence imaging
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):13. https://doi.org/10.1167/iovs.65.14.13

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics October 2024

Multicenter Normative Data for Mesopic Microperimetry

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Maximilian Pfau; Jasleen K. Jolly; Jason Charng; Leon von der Emde; Philipp L. Müller; Georg Ansari; Kristina Pfau; Fred K. Chen; Zhichao Wu
TAGS: calibration, eye, goodness of fit, perimetry, regression analysis, vision, follow-up, performance measures, datasets
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):27. https://doi.org/10.1167/iovs.65.12.27

Includes: Supplemental Content

Retina July 2024

Microperimetry Characteristics of Regions With a Truly Nonresponding Location: Implications for Atrophic Age-Related Macular Degeneration

PDF

Zhichao Wu; Maximilian Pfau; Monika Fleckenstein; Robyn H. Guymer
TAGS: age-related macular degeneration, nonexudative, atrophic condition of skin, cohort studies, scotoma, false-positive results, eye, computer simulation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):44. https://doi.org/10.1167/iovs.65.8.44

Retina July 2024

Sequence of Morphological Changes Preceding Atrophy in Intermediate AMD Using Deep Learning

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Sophie Riedl; Ursula Schmidt-Erfurth; Antoine Rivail; Klaudia Birner; Julia Mai; Wolf-Dieter Vogl; Zhichao Wu; Robyn H. Guymer; Hrvoje Bogunović; Gregor S. Reiter
TAGS: atrophy, cohort studies, deep learning, drusen, diagnostic imaging, eye, atrophic condition of skin
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):30. https://doi.org/10.1167/iovs.65.8.30

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Association of Mesopic Visual Sensitivities with automatically segmented Retinal Pigment Epithelium and Outer Retinal Atrophy (RORA) on Ocular Coherence Tomography (OCT)

Ana Paula Ribeiro Reis; Taha Soomro; Dun Jack Fu; Gunjan Naik; Gongyu Zhang; Alan Sousa da Silva; Ismail Moghul; Pallavi Bagga; Praveen J Patel; Nikolas Pontikos; Robyn H Guymer; Zhichao Wu; Konstantinos Balaskas

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3760.

ARVO Annual Meeting Abstract June 2024

Patient-tailored fundus-controlled perimetry testing in intermediate and early atrophic age-related macular degeneration

Steffen Schmitz-Valckenberg; Petrus Chang; Monika Fleckenstein; Frank G Holz; Zhichao Wu; Robyn H Guymer; Liang Liu; Hao Chen; Maximilian Pfau

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2794.

ARVO Annual Meeting Abstract June 2024

Validating a Confirmatory Structure-Function Model Prognostic of Progression of Intermediate AMD: MACUSTAR Study Primary Endpoint Analysis

Charlotte Behning; Jan Henrik Terheyden; Robert Finger; Hannah M P Dunbar; Marlene Sassmannshausen; Adnan Tufail; David P. Crabb; Alison M Binns; Zhichao Wu; Robyn H Guymer; Nadia Zakaria; Sergio Leal; Steffen Schmitz-Valckenberg; Ulrich F O Luhmann; Matthias Schmid; Frank G Holz

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4314.

ARVO Annual Meeting Abstract June 2024

Cross-modality annotation software (XMAS) - a tool for retinal image analysis

Peter van Wijngaarden; Maime Jannaud; Darvy Dang; Francis Labrecque; Zhichao Wu; Lauren Hodgson; Himeesh Kumar; Kai Lyn Goh; Bhaj Grewal; David Cordeiro Sousa; Meghna Burmi; Gizem Ashraf; Robyn H Guymer; Roderick O'Day; Xavier Hadoux

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5949.

ARVO Annual Meeting Abstract June 2024

Artificial Intelligence Quantified Outer Retinal Disruption On Optical Coherence Tomography As Clinical Endpoints For Geographic Atrophy

Adam Pely; Simon S. Gao; Katie M Litts; Zhichao Wu; Theodore Leng; Verena Steffen; Hao Chen; Dolly Shuo-Teh Chang; Mohsen Hejrati; Miao Zhang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2344.

ARVO Annual Meeting Abstract June 2024

On the Edge: Quantitative Analysis of Retinal Layer Thickness Surrounding Geographic Atrophy Lesions Using OCT

Joseph Blair; Zhichao Wu; Romina Lasagni Vitar; Anastasiia Mishchuk; Lauren Hodgson; Robyn H Guymer; Sandro De Zanet

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5474.

ARVO Annual Meeting Abstract June 2024

Identification of Anatomical Risk Factors for Nascent Geographic Atrophy Onset Using Artificial Intelligence

Somaye Hashemifar; Claudia Iriondo; Heming Yao; Zhichao Wu; Robyn H Guymer; Simon S. Gao; Hao Chen; Jiameng Zhang; Mohsen Hejrati; Miao Zhang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5654.

Artificial Intelligence June 2024

Deep Neural Networks for Automated Outer Plexiform Layer Subsidence Detection on Retinal OCT of Patients With Intermediate AMD

PDF

Guilherme Aresta; Teresa Araujo; Gregor S. Reiter; Julia Mai; Sophie Riedl; Christoph Grechenig; Robyn H. Guymer; Zhichao Wu; Ursula Schmidt-Erfurth; Hrvoje Bogunovic
TAGS: biological markers, datasets, lead, volume, eye, deep learning
Trans. Vis. Sci. Tech.. 2024; 13(6):7. https://doi.org/10.1167/tvst.13.6.7

Retina January 2024

Visual Sensitivity Loss in Geographic Atrophy: Structure–Function Evaluation Using Defect-Mapping Microperimetry

PDF

Zhichao Wu; Xavier Hadoux; Maxime Jannaud; Emily K. Glover; Erin E. Gee; Lauren A. B. Hodgson; Peter van Wijngaarden; Robyn H. Guymer
TAGS: age-related macular degeneration, nonexudative, eye, vision
Invest. Ophthalmol. Vis. Sci.. 2024; 65(1):36. https://doi.org/10.1167/iovs.65.1.36

Includes: Supplemental Content

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Translating nascent Geographic Atrophy definition into measurable biomarkers in OCT

Comprehensive Evaluation of OCT Biomarkers in Intermediate Age-Related Macular Degeneration for Predicting Disease Progression

Customized evaluation of progressive visual sensitivity loss in geographic atrophy to improve the power of clinical trials

Detecting Nascent Geographic Atrophy and Large Choroidal Signal Hypertransmission on OCT using Deep Learning

Predicting Visual Sensitivity Loss in Eyes with Geographic Atrophy using OCT Imaging and Fundus Autofluorescence

Targeted Defect-Mapping Microperimetry in Geographic Atrophy – A Sensitive Functional Outcome Measure for Intervention Trials

The chromosome 10 rs11200638 polymorphism, reticular pseudodrusen and rod-mediated dark adaptation

Longitudinal Changes of Visual Sensitivity With Geographic Atrophy Progression Assessed by Defect-Mapping Microperimetry

Multicenter Normative Data for Mesopic Microperimetry

Microperimetry Characteristics of Regions With a Truly Nonresponding Location: Implications for Atrophic Age-Related Macular Degeneration

Sequence of Morphological Changes Preceding Atrophy in Intermediate AMD Using Deep Learning

Association of Mesopic Visual Sensitivities with automatically segmented Retinal Pigment Epithelium and Outer Retinal Atrophy (RORA) on Ocular Coherence Tomography (OCT)

Patient-tailored fundus-controlled perimetry testing in intermediate and early atrophic age-related macular degeneration

Validating a Confirmatory Structure-Function Model Prognostic of Progression of Intermediate AMD: MACUSTAR Study Primary Endpoint Analysis

Cross-modality annotation software (XMAS) - a tool for retinal image analysis

Artificial Intelligence Quantified Outer Retinal Disruption On Optical Coherence Tomography As Clinical Endpoints For Geographic Atrophy

On the Edge: Quantitative Analysis of Retinal Layer Thickness Surrounding Geographic Atrophy Lesions Using OCT

Identification of Anatomical Risk Factors for Nascent Geographic Atrophy Onset Using Artificial Intelligence

Deep Neural Networks for Automated Outer Plexiform Layer Subsidence Detection on Retinal OCT of Patients With Intermediate AMD

Visual Sensitivity Loss in Geographic Atrophy: Structure–Function Evaluation Using Defect-Mapping Microperimetry

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