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ARVO Annual Meeting Abstract June 2020

Development of pegylated arginase 1 as a therapy for retinal ischemic injury

Abdelrahman Y. Fouda; Zhimin Xu; Esraa Shosha; Paul Ning-Man Cheng; S. Priya Narayanan; Robert W Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4052. doi:

ARVO Annual Meeting Abstract June 2020

Sigma 1 Receptor (Sig1R) activation: a novel therapy for neurovascular injury in Retinopathy of Prematurity (ROP)

Jing Wang; Haiyan Xiao; Zhimin Xu; Ruth B Caldwell; Sylvia B Smith

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5411. doi:

Retina March 2020

Utility of LysM-cre and Cdh5-cre Driver Mice in Retinal and Brain Research: An Imaging Study Using tdTomato Reporter Mouse

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Abdelrahman Y. Fouda; Zhimin Xu; S. Priya Narayanan; R. William Caldwell; Ruth B. Caldwell
TAGS: adult, brain, mice, retina, diagnostic imaging, microglia, neurons
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):51. doi: https://doi.org/10.1167/iovs.61.3.51

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract July 2019

Targeting neurovascular injury: Arginase 1 promotes angiogenic repair and limits neurodegeneration

Ruth B Caldwell; Abdelrahman Y Fouda; Zhimin Xu; Jutamas Suwanpradid; Modesto Rojas; Esraa Shosha; Chintan Patel; Ji Xing; S. Priya Narayanan; Robert W. Caldwell

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3258. doi:

Retina May 2018

Neurofibromin Deficiency Induces Endothelial Cell Proliferation and Retinal Neovascularization

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Hanfang Zhang; Farlyn Z. Hudson; Zhimin Xu; Rebekah Tritz; Modesto Rojas; Chintan Patel; Stephen B. Haigh; Zsuzsanna Bordán; David A. Ingram; David J. Fulton; Neal L. Weintraub; Ruth B. Caldwell; Brian K. Stansfield
TAGS: endothelial cells, neovascularization, pathologic, neurofibromatosis type 1 protein, retinal neovascularization, vascular endothelial growth factor a, mice, oxygen, hypoxia, proto-oncogene proteins c-akt, retinal diseases
Invest. Ophthalmol. Vis. Sci.. 2018; 59(6):2520-2528. doi: https://doi.org/10.1167/iovs.17-22588

ARVO Annual Meeting Abstract June 2017

Protective Role of Arginase 1 in Retinal Ischemia Reperfusion Injury

Abdelrahman Fouda; Zhimin Xu; Esraa Shosha; William Caldwell; S. Priya Narayanan; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5895. doi:

ARVO Annual Meeting Abstract June 2017

Spermine Oxidase: a novel mediator of diabetes-induced retinal neurodegeneration

S. Priya Narayanan; Alan Saul; Zhimin Xu; Prahalathan Pichavaram

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5198. doi:

ARVO Annual Meeting Abstract June 2017

Overexpression of spermine oxidase increases neuronal death and glial activation in a model of retinal excitotoxicity

PRAHALATHAN PICHAVARAM; Chintan Patel; Zhimin Xu; Esraa Shosha; Manuela Cervelli; Ruth B Caldwell; S. Priya Narayanan

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5891. doi:

ARVO Annual Meeting Abstract June 2017

Retinal Ischemia Reperfusion: Role of Arginase 2

Esraa Shosha; Abdelrahman Fouda; Ahmed Ibrahim; Mohamed Al-Sayed Al-Shabrawey; Zhimin Xu; Tahira Lemtalsi; William Caldwell; S. Priya Narayanan; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5899. doi:

ARVO Annual Meeting Abstract June 2017

Arginase 2 deletion prevents optic nerve crush-induced retinal degeneration

Ruth B Caldwell; Zhimin Xu; S. Priya Narayanan; Tahira Lemtalsi; Chintan Patel; Esraa Shosha; William Caldwell

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1760. doi:

ARVO Annual Meeting Abstract September 2016

Arginase 2 deletion limits neuroglial injury following optic nerve trauma

Zhimin Xu; S.Priya Narayanan; Chintan Patel; Esraa Shosha; R. William Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):742. doi:

ARVO Annual Meeting Abstract September 2016

Neurovascular Injury after Retinal Ischemia Reperfusion Insult: Contrasting Roles of Arginase Enzyme Isoforms

Esraa Shosha; Zhimin Xu; Harumasa Yokota; Ji Xing; R. William Caldwell; Alan Saul; S.Priya Narayanan; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):746. doi:

ARVO Annual Meeting Abstract September 2016

Treatment with polyamine oxidase inhibitor reduces excitotoxicity-mediated retinal neuro-inflammation

Chintan Patel; Prahalathan Pichavaram; Zhimin Xu; Esraa Shosha; Ruth B Caldwell; S.Priya Narayanan

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4416. doi:

ARVO Annual Meeting Abstract September 2016

Blockade of NOX2 or arginase prevents diabetes-induced retinal endothelial cell senescence by restoring NO bioavailability

Modesto Rojas; Tahira Lemtalsi; Haroldo A Toque; Zhimin Xu; Esraa Shosha; David Fulton; R. William Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3224. doi:

ARVO Annual Meeting Abstract June 2015

Mechanisms of Neurovascular protection in Retinal Ischemia Reperfusion Injury: Role of Arginase

Esraa Shosha; Zhimin Xu; Tahira Lemtalsi; S Priya Narayanan; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):14. doi:

ARVO Annual Meeting Abstract June 2015

Polyamine oxidase: a novel mediator of hyperoxia-induced retinal neuro-vascular injury

Chintan Patel; Ji Xing; Zhimin Xu; Tahira Lemtalsi; Diego G Espinosa-Heidmann; Tam Nguyen; Ruth B Caldwell; S Priya Narayanan

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):19. doi:

ARVO Annual Meeting Abstract April 2014

Inhibition of polyamine oxidase reduces hyperoxia-mediated retinal neuro-vascular injury in a model of retinopathy of prematurity

S. Priya Narayanan; Zhimin Xu; Tahira Lemtalsi; Robert William Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1716. doi:

ARVO Annual Meeting Abstract April 2014

Endoplasmic Reticulum Stress-regulated CXCL10/CXCR3 pathway mediates inflammation and neuronal injury after retinal ischemia

Yonju Ha; Hua Liu; Zhimin Xu; Harumasa Yokota; Tahira Lemtalsi; Sylvia B Smith; Robert William Caldwell; Massoud Motamedi; Ruth B Caldwell; Wenbo Zhang

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2178. doi:

ARVO Annual Meeting Abstract April 2014

Mechanistic role of arginase in inducing endothelial cell senescence in diabetic retinopathy

Esraa Shosha; Tahira Lemtalsi; Zhimin Xu; Robert William Caldwell; Ruth B Caldwell; S. Priya Narayanan

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3557. doi:

ARVO Annual Meeting Abstract April 2014

Diabetes induced-injury in retina and bone marrow cells involves NOX2-induced activation of arginase

Modesto Antonio Rojas; S. Priya Narayanan; Haroldo A Toque; Tahira Lemtalsi; Zhimin Xu; David Fulton; Robert William Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4905. doi:

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Development of pegylated arginase 1 as a therapy for retinal ischemic injury

Sigma 1 Receptor (Sig1R) activation: a novel therapy for neurovascular injury in Retinopathy of Prematurity (ROP)

Utility of LysM-cre and Cdh5-cre Driver Mice in Retinal and Brain Research: An Imaging Study Using tdTomato Reporter Mouse

Targeting neurovascular injury: Arginase 1 promotes angiogenic repair and limits neurodegeneration

Neurofibromin Deficiency Induces Endothelial Cell Proliferation and Retinal Neovascularization

Protective Role of Arginase 1 in Retinal Ischemia Reperfusion Injury

Spermine Oxidase: a novel mediator of diabetes-induced retinal neurodegeneration

Overexpression of spermine oxidase increases neuronal death and glial activation in a model of retinal excitotoxicity

Retinal Ischemia Reperfusion: Role of Arginase 2

Arginase 2 deletion prevents optic nerve crush-induced retinal degeneration

Arginase 2 deletion limits neuroglial injury following optic nerve trauma

Neurovascular Injury after Retinal Ischemia Reperfusion Insult: Contrasting Roles of Arginase Enzyme Isoforms

Treatment with polyamine oxidase inhibitor reduces excitotoxicity-mediated retinal neuro-inflammation

Blockade of NOX2 or arginase prevents diabetes-induced retinal endothelial cell senescence by restoring NO bioavailability

Mechanisms of Neurovascular protection in Retinal Ischemia Reperfusion Injury: Role of Arginase

Polyamine oxidase: a novel mediator of hyperoxia-induced retinal neuro-vascular injury

Inhibition of polyamine oxidase reduces hyperoxia-mediated retinal neuro-vascular injury in a model of retinopathy of prematurity

Endoplasmic Reticulum Stress-regulated CXCL10/CXCR3 pathway mediates inflammation and neuronal injury after retinal ischemia

Mechanistic role of arginase in inducing endothelial cell senescence in diabetic retinopathy

Diabetes induced-injury in retina and bone marrow cells involves NOX2-induced activation of arginase

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