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ARVO Annual Meeting Abstract June 2024

Does targeting the ornithine decarboxylase/polyamine pathway offer a novel therapy for retinopathy of prematurity?

Syed Adeel Zaidi; Porsche Sandow; Rayyan Khan; Zhimin Xu; Tahira Lemtalsi; Modesto Antonio Rojas; Brian Stansfield; R.William Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):265.

ARVO Annual Meeting Abstract June 2023

Is acyl-coenzyme A: cholesterol transferase (ACAT1) a mediator of neurovascular injury in diabetic retinopathy?

MODESTO ANTONIO ROJAS; Syed Adeel Zaidi; Tahira Lemtalsi; Zhimin Xu; Porsche Sandow; R William Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3776.

ARVO Annual Meeting Abstract June 2022

Retinal ganglion cell specific deletion of arginase-2 preserves visual function after optic nerve crush

Syed Adeel Zaidi; zhimin Xu; Tahira Lemtalsi; Abdelrahman Fouda; R. William Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):863.

ARVO Annual Meeting Abstract June 2022

Sigma 1 Receptor (Sig1R) activation attenuates vasculopathy associated with Retinopathy of Prematurity (ROP)

Jing Wang; Haiyan Xiao; zhimin Xu; Ruth B Caldwell; Sylvia B Smith

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):784 – F0343.

ARVO Annual Meeting Abstract June 2022

Investigation of the retinal metabolic function in type 1 diabetic Akita mice

Abdelrahman Fouda; Esraa Shosha; Luke Qin; Tahira Lemtalsi; Syed Adeel Zaidi; Modesto Antonio Rojas; zhimin xu; R. William Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3598 – A0053.

ARVO Annual Meeting Abstract June 2021

Pegylated Arginase 1 as a Treatment for Acute Central Nervous System (CNS) Injury

Abdelrahman Fouda; Wael Eldahshan; Zhimin Xu; Tahira Lemtalsi; Esraa Shosha; Paul Ning-Man Cheng; S. Priya Narayanan; Robert W Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2999.

ARVO Annual Meeting Abstract June 2020

Development of pegylated arginase 1 as a therapy for retinal ischemic injury

Abdelrahman Y. Fouda; Zhimin Xu; Esraa Shosha; Paul Ning-Man Cheng; S. Priya Narayanan; Robert W Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4052.

ARVO Annual Meeting Abstract June 2020

Sigma 1 Receptor (Sig1R) activation: a novel therapy for neurovascular injury in Retinopathy of Prematurity (ROP)

Jing Wang; Haiyan Xiao; Zhimin Xu; Ruth B Caldwell; Sylvia B Smith

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5411.

Retina March 2020

Utility of LysM-cre and Cdh5-cre Driver Mice in Retinal and Brain Research: An Imaging Study Using tdTomato Reporter Mouse

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Abdelrahman Y. Fouda; Zhimin Xu; S. Priya Narayanan; R. William Caldwell; Ruth B. Caldwell
TAGS: adult, brain, mice, retina, diagnostic imaging, microglia, neurons
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):51. https://doi.org/10.1167/iovs.61.3.51

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract July 2019

Targeting neurovascular injury: Arginase 1 promotes angiogenic repair and limits neurodegeneration

Ruth B Caldwell; Abdelrahman Y Fouda; Zhimin Xu; Jutamas Suwanpradid; Modesto Rojas; Esraa Shosha; Chintan Patel; Ji Xing; S. Priya Narayanan; Robert W. Caldwell

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3258.

Retina May 2018

Neurofibromin Deficiency Induces Endothelial Cell Proliferation and Retinal Neovascularization

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Hanfang Zhang; Farlyn Z. Hudson; Zhimin Xu; Rebekah Tritz; Modesto Rojas; Chintan Patel; Stephen B. Haigh; Zsuzsanna Bordán; David A. Ingram; David J. Fulton; Neal L. Weintraub; Ruth B. Caldwell; Brian K. Stansfield
TAGS: endothelial cells, neovascularization, pathologic, neurofibromatosis type 1 protein, retinal neovascularization, vascular endothelial growth factor a, mice, oxygen, hypoxia, proto-oncogene proteins c-akt, retinal diseases
Invest. Ophthalmol. Vis. Sci.. 2018; 59(6):2520-2528. https://doi.org/10.1167/iovs.17-22588

ARVO Annual Meeting Abstract June 2017

Protective Role of Arginase 1 in Retinal Ischemia Reperfusion Injury

Abdelrahman Fouda; Zhimin Xu; Esraa Shosha; William Caldwell; S. Priya Narayanan; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5895.

ARVO Annual Meeting Abstract June 2017

Arginase 2 deletion prevents optic nerve crush-induced retinal degeneration

Ruth B Caldwell; Zhimin Xu; S. Priya Narayanan; Tahira Lemtalsi; Chintan Patel; Esraa Shosha; William Caldwell

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1760.

ARVO Annual Meeting Abstract June 2017

Spermine Oxidase: a novel mediator of diabetes-induced retinal neurodegeneration

S. Priya Narayanan; Alan Saul; Zhimin Xu; Prahalathan Pichavaram

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5198.

ARVO Annual Meeting Abstract June 2017

Overexpression of spermine oxidase increases neuronal death and glial activation in a model of retinal excitotoxicity

PRAHALATHAN PICHAVARAM; Chintan Patel; Zhimin Xu; Esraa Shosha; Manuela Cervelli; Ruth B Caldwell; S. Priya Narayanan

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5891.

ARVO Annual Meeting Abstract June 2017

Retinal Ischemia Reperfusion: Role of Arginase 2

Esraa Shosha; Abdelrahman Fouda; Ahmed Ibrahim; Mohamed Al-Sayed Al-Shabrawey; Zhimin Xu; Tahira Lemtalsi; William Caldwell; S. Priya Narayanan; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5899.

ARVO Annual Meeting Abstract September 2016

Arginase 2 deletion limits neuroglial injury following optic nerve trauma

Zhimin Xu; S.Priya Narayanan; Chintan Patel; Esraa Shosha; R. William Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):742.

ARVO Annual Meeting Abstract September 2016

Neurovascular Injury after Retinal Ischemia Reperfusion Insult: Contrasting Roles of Arginase Enzyme Isoforms

Esraa Shosha; Zhimin Xu; Harumasa Yokota; Ji Xing; R. William Caldwell; Alan Saul; S.Priya Narayanan; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):746.

ARVO Annual Meeting Abstract September 2016

Blockade of NOX2 or arginase prevents diabetes-induced retinal endothelial cell senescence by restoring NO bioavailability

Modesto Rojas; Tahira Lemtalsi; Haroldo A Toque; Zhimin Xu; Esraa Shosha; David Fulton; R. William Caldwell; Ruth B Caldwell

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3224.

ARVO Annual Meeting Abstract September 2016

Treatment with polyamine oxidase inhibitor reduces excitotoxicity-mediated retinal neuro-inflammation

Chintan Patel; Prahalathan Pichavaram; Zhimin Xu; Esraa Shosha; Ruth B Caldwell; S.Priya Narayanan

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4416.

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Does targeting the ornithine decarboxylase/polyamine pathway offer a novel therapy for retinopathy of prematurity?

Is acyl-coenzyme A: cholesterol transferase (ACAT1) a mediator of neurovascular injury in diabetic retinopathy?

Retinal ganglion cell specific deletion of arginase-2 preserves visual function after optic nerve crush

Sigma 1 Receptor (Sig1R) activation attenuates vasculopathy associated with Retinopathy of Prematurity (ROP)

Investigation of the retinal metabolic function in type 1 diabetic Akita mice

Pegylated Arginase 1 as a Treatment for Acute Central Nervous System (CNS) Injury

Development of pegylated arginase 1 as a therapy for retinal ischemic injury

Sigma 1 Receptor (Sig1R) activation: a novel therapy for neurovascular injury in Retinopathy of Prematurity (ROP)

Utility of LysM-cre and Cdh5-cre Driver Mice in Retinal and Brain Research: An Imaging Study Using tdTomato Reporter Mouse

Targeting neurovascular injury: Arginase 1 promotes angiogenic repair and limits neurodegeneration

Neurofibromin Deficiency Induces Endothelial Cell Proliferation and Retinal Neovascularization

Protective Role of Arginase 1 in Retinal Ischemia Reperfusion Injury

Arginase 2 deletion prevents optic nerve crush-induced retinal degeneration

Spermine Oxidase: a novel mediator of diabetes-induced retinal neurodegeneration

Overexpression of spermine oxidase increases neuronal death and glial activation in a model of retinal excitotoxicity

Retinal Ischemia Reperfusion: Role of Arginase 2

Arginase 2 deletion limits neuroglial injury following optic nerve trauma

Neurovascular Injury after Retinal Ischemia Reperfusion Insult: Contrasting Roles of Arginase Enzyme Isoforms

Blockade of NOX2 or arginase prevents diabetes-induced retinal endothelial cell senescence by restoring NO bioavailability

Treatment with polyamine oxidase inhibitor reduces excitotoxicity-mediated retinal neuro-inflammation

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