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ARVO Annual Meeting Abstract June 2023

Digital droplet PCR enables genotyping the red-green opsin array for clinical diagnostics

Amelia Naik; Bin Guan; Deena Elul; Edda Haggerty; Wadih M Zein; Cara Lwin; Zhiyu Li; Delphine Blain; Brian Patrick Brooks; Santa J Tumminia; David H Brainard; Geoffrey K Aguirre; Robert B. Hufnagel

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4534.

ARVO Annual Meeting Abstract June 2023

A precision genomics approach to validating NOLC1 as the cause of a unique nanophthalmos-microcephaly syndrome

Sairah Yousaf; Blake Carrington; Zhiyu Li; Mones Abu-Asab; Laryssa Huryn; Raman Sood; Robert B. Hufnagel

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4525.

ARVO Annual Meeting Abstract June 2022

Models of Autosomal Dominant Optic Atrophy (ADOA) using OPA1 haploinsufficient iPSCs and response to Targeted Augmentation of Nuclear Gene Output (TANGO) Antisense Oligonucleotides (ASOs) Treatment

Raymond Oh; Brittany Slipp; Aditya Venkatesh; Syed Ali; Zhiyu Li; Robert B Hufnagel; Isabel Aznarez; Gene Liau; Jeff Hoger

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1895 – A0041.

ARVO Annual Meeting Abstract June 2021

Antisense oligonucleotide mediated increase in OPA1 improves mitochondrial function in fibroblasts derived from patients with autosomal dominant optic atrophy (ADOA)

Aditya Venkatesh; Syed Ali; Raymond S Oh; Donna Sonntag; Zhiyu Li; Taylor McKenty; Brittany A Slipp; Robert B Hufnagel; Jeffrey Hoger; Gene Liau

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1482.

ARVO Annual Meeting Abstract June 2020

Antisense oligonucleotide mediated increase of OPA1 expression using TANGO technology for the treatment of autosomal dominant optic atrophy

ADITYA VENKATESH; Zhiyu Li; Anne Christiansen; Kian Huat Lim; Jacob Kach; Robert Hufnagel; Isabel Aznarez; Gene Liau

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2755.

ARVO Annual Meeting Abstract July 2019

Human Umbilical Cord Mesenchymal Stem Cells protect against ocular hypertension induced retinal injury via toll-like receptor 4 (TLR4) pathway

Shangli Ji; Jie Xiao; Zhiyuan LI; Shibo Tang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):634.

ARVO Annual Meeting Abstract July 2018

Efficacy of IL-12/23 inhibition for the Treatment of Active Sight-Threatening Uveitis: A Pilot Study

Lotta Utriainen; Jung Wha Lee; Zhiyu Li; Benjamin Chaon; Ian Thompson; Benjamin Chaigne-Delalande; H Nida Nida Sen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5948.

ARVO Annual Meeting Abstract July 2018

Rescue of retinal ganglion cells by human umbilical cord mesenchymal stem cells in a microbead induced ocular hypertension rat model

Shangli Ji; Zhiyuan Li; Heping Xu; Jiansu Chen; Shibo Tang

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6111.

ARVO Annual Meeting Abstract June 2017

The suppressive effect of the epigenetic drug, Givinostat (ITF2357), on peripheral blood leukocytes from uveitis patients

Lauren P Schewitz-Bowers; Philippa J P Lait; Wei Chen; Ester Carreno; Xiao Hu; Zhiyu Li; Jing Chen; Kara M Ponsford; Andrew D Dick; Lai Wei; Rachel R Caspi; Richard W J Lee; Benjamin Chaigne-Delalande

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):510.

ARVO Annual Meeting Abstract June 2017

Gut Microbiome in Uveitis

H Nida Sen; Benjamin Chaigne-Delalande; Zhiyu Li; Venu Lagishetty; Jonathan Jacobs; Jonathan Braun

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):846.

Immunology and Microbiology August 2016

Modulation of Immune Responses by Extracellular Vesicles From Retinal Pigment Epithelium

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Jared E. Knickelbein; Baoying Liu; Anush Arakelyan; Sonia Zicari; Susan Hannes; Ping Chen; Zhiyu Li; Jean-Charles Grivel; Benjamin Chaigne-Delalande; H. Nida Sen; Leonid Margolis; Robert B. Nussenblatt
TAGS: cytokine, extracellular vesicles, immune response, monocytes, retinal pigment epithelium, t-lymphocytes, tumor necrosis factors, flow cytometry, phenotype, western blotting
Invest. Ophthalmol. Vis. Sci.. 2016; 57(10):4101-4107. https://doi.org/10.1167/iovs.15-18353

Immunology and Microbiology April 2016

Elevated CD1c + Myeloid Dendritic Cell Proportions Associate With Clinical Activity and Predict Disease Reactivation in Noninfectious Uveitis

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Ping Chen; Cristhian A. Urzua; Jared E. Knickelbein; Jane S. Kim; Zhiyu Li; Susan Hannes; David Kuo; Benjamin Chaigne-Delalande; Karen Armbrust; William Tucker; Baoying Liu; Elvira Agrón; H. Nida Sen; Robert B. Nussenblatt
TAGS: dendritic cells, mdc protocol, uveitis
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):1765-1772. https://doi.org/10.1167/iovs.15-18357

ARVO Annual Meeting Abstract June 2015

Whole transcriptome profiling of peripheral CD4 + T-cells in age-related macular degeneration patients using RNA-seq

Han Si; Cristhian A Urzua; Baoying Liu; Zhiyu Li; Amol Sura; adrianna lee; Robert B Nussenblatt

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):820.

ARVO Annual Meeting Abstract June 2015

Expression of MSR-1—a Class-A Macrophage Scavenger Receptor—May Be Altered in Ocular Sarcoidosis

Amol Sura; Baoying Liu; Zhiyu Li; Susan Hannes; Siamon Gordon; Robert B Nussenblatt

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):854.

ARVO Annual Meeting Abstract June 2015

Effect of HDACi Givinostat in Treating Experimental Ocular Autoimmunity

Baoying Liu; Zhiyu Li; Phyllis Silver; Cuiyan Tan; Ping Chen; Chi-Chao Chan; Robert B Nussenblatt

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):882.

ARVO Annual Meeting Abstract June 2015

Peripheral Monocyte Subset-Derived Macrophages Show Distinct Expression Kinetics of Immune Biomarkers Associated with Ocular Autoimmunity

Susan Hannes; Baoying Liu; Zhiyu Li; Diamond Ling; H Nida Sen; Robert B Nussenblatt

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):884.

ARVO Annual Meeting Abstract April 2014

Increased expression of p21 in CD14+ human monocytes correlates with telomere shortening in ocular sarcoidosis patients

Susan K Hannes; Baoying Liu; H Nida Sen; Shayma Jawad; Zhiyu Li; Robert B Nussenblatt

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1857.

ARVO Annual Meeting Abstract April 2014

Increased Blood CD1c(high) Myeloid Dendritic Cells with Low Antigen Uptake Enhance CD4 Helper T cell Responses in Noninfectious Uveitis

Ping Chen; Lai Wei; Baoying Liu; Tiaojiang Xiao; Sima Hirani; Zhiyu Li; Shayma Jawad; Richard W J Lee; H Nida Sen; Robert B Nussenblatt

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4062.

Immunology and Microbiology September 2013

The Role of Macrophage Class A Scavenger Receptors in a Laser-Induced Murine Choroidal Neovascularization Model

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Shayma Jawad; Baoying Liu; Zhiyu Li; Robert Katamay; Mercedes Campos; Lai Wei; H. Nida Sen; Diamond Ling; Fernando Martinez Estrada; Juan Amaral; Chi-Chao Chan; Robert Fariss; Siamon Gordon; Robert B. Nussenblatt
TAGS: choroidal neovascularization, eye, lasers, macrophages, receptors, scavenger
Invest. Ophthalmol. Vis. Sci.. 2013; 54(9):5959-5970. https://doi.org/10.1167/iovs.12-11380

ARVO Annual Meeting Abstract June 2013

Dendritic cells from uveitis patients have a mature phenotype and a reduced capacity to take up antigen

Ping Chen; Baoying Liu; Richard Lee; H Nida Sen; Zhiyu Li; Shayma Jawad; Sima Hirani; Lai Wei; Robert Nussenblatt

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2034.

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Digital droplet PCR enables genotyping the red-green opsin array for clinical diagnostics

A precision genomics approach to validating NOLC1 as the cause of a unique nanophthalmos-microcephaly syndrome

Models of Autosomal Dominant Optic Atrophy (ADOA) using OPA1 haploinsufficient iPSCs and response to Targeted Augmentation of Nuclear Gene Output (TANGO) Antisense Oligonucleotides (ASOs) Treatment

Antisense oligonucleotide mediated increase in OPA1 improves mitochondrial function in fibroblasts derived from patients with autosomal dominant optic atrophy (ADOA)

Antisense oligonucleotide mediated increase of OPA1 expression using TANGO technology for the treatment of autosomal dominant optic atrophy

Human Umbilical Cord Mesenchymal Stem Cells protect against ocular hypertension induced retinal injury via toll-like receptor 4 (TLR4) pathway

Efficacy of IL-12/23 inhibition for the Treatment of Active Sight-Threatening Uveitis: A Pilot Study

Rescue of retinal ganglion cells by human umbilical cord mesenchymal stem cells in a microbead induced ocular hypertension rat model

The suppressive effect of the epigenetic drug, Givinostat (ITF2357), on peripheral blood leukocytes from uveitis patients

Gut Microbiome in Uveitis

Modulation of Immune Responses by Extracellular Vesicles From Retinal Pigment Epithelium

Elevated CD1c + Myeloid Dendritic Cell Proportions Associate With Clinical Activity and Predict Disease Reactivation in Noninfectious Uveitis

Whole transcriptome profiling of peripheral CD4 + T-cells in age-related macular degeneration patients using RNA-seq

Expression of MSR-1—a Class-A Macrophage Scavenger Receptor—May Be Altered in Ocular Sarcoidosis

Effect of HDACi Givinostat in Treating Experimental Ocular Autoimmunity

Peripheral Monocyte Subset-Derived Macrophages Show Distinct Expression Kinetics of Immune Biomarkers Associated with Ocular Autoimmunity

Increased expression of p21 in CD14+ human monocytes correlates with telomere shortening in ocular sarcoidosis patients

Increased Blood CD1c(high) Myeloid Dendritic Cells with Low Antigen Uptake Enhance CD4 Helper T cell Responses in Noninfectious Uveitis

The Role of Macrophage Class A Scavenger Receptors in a Laser-Induced Murine Choroidal Neovascularization Model

Dendritic cells from uveitis patients have a mature phenotype and a reduced capacity to take up antigen

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