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ARVO Annual Meeting Abstract June 2020

Oral delivery of a novel small molecule drug, OCX063, protects against vascular leakage and fibrosis in a rodent model of neovascular age-related macular degeneration.

Michelle Pauline Papadimitriou; Zsolt Ablonczy; Andy Whitlock; Erica Fletcher; Fay Lin Khong; Darren Kelly

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3975. doi:

ARVO Annual Meeting Abstract July 2019

Quantitation of fibrosis in a rat model of laser-induced CNV

Zsolt Ablonczy; Christopher Schillo; David A Hollander; Andy Whitlock

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1256. doi:

ARVO Annual Meeting Abstract July 2018

Delay of oscillatory potentials links animal models to diabetes in the human eye

Zsolt Ablonczy; Cristiana Giancarlo; Christopher Schillo; Kortni Violette; Dennis Guberski; Barak Yahalom; Laura Belen; Claire Gelfman; April Hall; David Hollander; Andy Whitlock

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4445. doi:

ARVO Annual Meeting Abstract June 2017

Association between IOP and retinal thickness following intravitreal triamcinolone injections in DME patients

Mohammad Dahrouj; Jan A Kylstra; Bethany Wolf; Zsolt Ablonczy; Craig E Crosson

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):243. doi:

ARVO Annual Meeting Abstract June 2017

Improved spectral recovery and tissue localization of autofluorescence (AF) signatures in donor eyes with age-related macular degeneration (AMD) using multi excitation hyperspectral AF imaging.

Taariq Mohammed; Yuehong Tong; Julia Margaret Agee; Neel Dey; Sungmin Hong; Rainer Heintzmann; Martin Hammer; Christine Curcio; Thomas Ach; Zsolt Ablonczy; Theodore Smith

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):383. doi:

ARVO Annual Meeting Abstract June 2017

Consistent Automatic Spectral Signature Recovery of Human retinal pigment epithelium (RPE) Lipofuscin Components and Drusen in Donors with Age-related Macular Degeneration (AMD) using Multi-Excitation Hyperspectral Autofluorescence (AF) Imaging.

Neel Dey; Sungmin Hong; Yuehong Tong; Taariq Mohammed; Rainer Heintzmann; Martin Hammer; Guido Gerig; Christine Curcio; Thomas Ach; Zsolt Ablonczy; Theodore Smith

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):399. doi:

ARVO Annual Meeting Abstract June 2017

Hyperspectral Autofluorescence (AF) and Mechanisms of Retinal Pigment Epithelium (RPE) Lipofuscin Loss in Age-Related Macular Degeneration (AMD)

Yuehong Tong; Julia Margaret Agee; Taariq Mohammed; Neel Dey; Sungmin Hong; Rainer Heintzmann; Martin Hammer; Guido Gerig; Christine A. Curcio; Thomas Ach; Zsolt Ablonczy; Theodore Smith

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):404. doi:

ARVO Annual Meeting Abstract September 2016

VEGF induced changes in RPE function are dependent on increased HDAC activity.

Zsolt Ablonczy; Danielle Desjardins; Yueying Liu; Jie Fan; Craig E Crosson

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

A2E adducts in the human retinal pigment epithelium

Masahiro Kono; Zsolt Ablonczy; Patrice W. Goletz; Joe G Hollyfield; Rosalie K Crouch

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1737. doi:

ARVO Annual Meeting Abstract September 2016

Hyperspectral Autofluorescence Characterization of Transition to Atrophy in Donor Eyes with Advanced Age-Related Macular Degeneration (AMD)

Yuehong Tong; Tal Ben Ami; Sungmin Hong; Rainer Heintzmann; Guido Gerig; Zsolt Ablonczy; Christine A Curcio; Thomas Ach; Theodore Smith

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):54. doi:

ARVO Annual Meeting Abstract September 2016

Hyperspectral Autofluorescence (AF) of Melanin-containing Organelles in Human Retinal Pigment Epithelium (RPE) with Late Age-related Macular Degeneration (AMD)

Tal Ben Ami; Yuehong Tong; Sungmin Hong; Rainer Heintzmann; Guido Gerig; Zsolt Ablonczy; Christine A Curcio; Thomas Ach; Theodore Smith

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1705. doi:

ARVO Annual Meeting Abstract September 2016

Altered Transepithelial Resistance of Induced Pluripotent Stem Cell-derived Retinal Pigment Epithelium Obtained from Age-related Macular Degeneration (AMD) Patients

Ernesto F Moreira; Jie Gong; Sibylle Rosendahl; Amanda Barrett; Mark Anthony Fields; Zsolt Ablonczy; Baerbel Rohrer; Lucian V Del Priore

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6034. doi:

ARVO Annual Meeting Abstract September 2016

Glycated-albumin induced RPE barrier breakdown is mediated by HDAC6

Danielle Desjardins; Yueying Liu; Jie Fan; Craig E Crosson; Zsolt Ablonczy

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

Retina May 2016

Progressive Early Breakdown of Retinal Pigment Epithelium Function in Hyperglycemic Rats

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Danielle M. Desjardins; Phil W. Yates; Mohammad Dahrouj; Yueying Liu; Craig E. Crosson; Zsolt Ablonczy
TAGS: hyperglycemia, hyperglycemic agents, rats, vascular endothelial growth factor a, retinal pigment epithelium, streptozocin, injections, diabetes mellitus
Invest. Ophthalmol. Vis. Sci.. 2016; 57(6):2706-2713. doi: https://doi.org/10.1167/iovs.15-18397

Articles May 2016

Spatial and Spectral Characterization of Human Retinal Pigment Epithelium Fluorophore Families by Ex Vivo Hyperspectral Autofluorescence Imaging

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Tal Ben Ami; Yuehong Tong; Alauddin Bhuiyan; Carrie Huisingh; Zsolt Ablonczy; Thomas Ach; Christine A. Curcio; R. Theodore Smith
TAGS: autofluorescence, biological response modifiers, body tissue, diagnostic imaging, eye, family
Trans. Vis. Sci. Tech.. 2016; 5(3):5. doi: https://doi.org/10.1167/tvst.5.3.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Ex Vivo Hyperspectral Autofluorescence (AF) Imaging of Retinal Pigment Epithelium (RPE) in Human Donor Eyes with Age-related Macular Degeneration (AMD)

Tal Ben Ami; Yuehong Tong; Paul Sajda; Zsolt Ablonczy; Christine A Curcio; Theodore Smith; Thomas Ach

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4369. doi:

ARVO Annual Meeting Abstract June 2015

The hyperglycemia-induced early retinal pigment epithelium dysfunction is mediated by vascular endothelial growth factor

Zsolt Ablonczy; Danielle Desjardins; Mohammad Dahrouj; Yueying Liu; Kumar Sambamurti; Craig E Crosson

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5176. doi:

ARVO Annual Meeting Abstract June 2015

Trichostatin A Rescues RPE Function in Diabetic Rats

Danielle Desjardins; Philip Yates; Yueying Liu; Craig E Crosson; Zsolt Ablonczy

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5178. doi:

ARVO Annual Meeting Abstract June 2015

Fluorescence and mass spectrometric imaging of monkey ( Cynomolgus) retinal pigment epithelium confirms the mismatching of lipofuscin and A2E distributions observed in human tissue

Patrick Pallitto; Zsolt Ablonczy; John E Donello; Yiannis Koutalos; Julia E Herrmann; Rosalie K Crouch

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2352. doi:

ARVO Annual Meeting Abstract June 2015

Components of human lipofuscin

Masahiro Kono; John E. Oatis; Zsolt Ablonczy; Patrice W. Goletz; Joe G Hollyfield; Rosalie K Crouch

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2381. doi:

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Oral delivery of a novel small molecule drug, OCX063, protects against vascular leakage and fibrosis in a rodent model of neovascular age-related macular degeneration.

Quantitation of fibrosis in a rat model of laser-induced CNV

Delay of oscillatory potentials links animal models to diabetes in the human eye

Association between IOP and retinal thickness following intravitreal triamcinolone injections in DME patients

Improved spectral recovery and tissue localization of autofluorescence (AF) signatures in donor eyes with age-related macular degeneration (AMD) using multi excitation hyperspectral AF imaging.

Consistent Automatic Spectral Signature Recovery of Human retinal pigment epithelium (RPE) Lipofuscin Components and Drusen in Donors with Age-related Macular Degeneration (AMD) using Multi-Excitation Hyperspectral Autofluorescence (AF) Imaging.

Hyperspectral Autofluorescence (AF) and Mechanisms of Retinal Pigment Epithelium (RPE) Lipofuscin Loss in Age-Related Macular Degeneration (AMD)

VEGF induced changes in RPE function are dependent on increased HDAC activity.

A2E adducts in the human retinal pigment epithelium

Hyperspectral Autofluorescence Characterization of Transition to Atrophy in Donor Eyes with Advanced Age-Related Macular Degeneration (AMD)

Hyperspectral Autofluorescence (AF) of Melanin-containing Organelles in Human Retinal Pigment Epithelium (RPE) with Late Age-related Macular Degeneration (AMD)

Altered Transepithelial Resistance of Induced Pluripotent Stem Cell-derived Retinal Pigment Epithelium Obtained from Age-related Macular Degeneration (AMD) Patients

Glycated-albumin induced RPE barrier breakdown is mediated by HDAC6

Progressive Early Breakdown of Retinal Pigment Epithelium Function in Hyperglycemic Rats

Spatial and Spectral Characterization of Human Retinal Pigment Epithelium Fluorophore Families by Ex Vivo Hyperspectral Autofluorescence Imaging

Ex Vivo Hyperspectral Autofluorescence (AF) Imaging of Retinal Pigment Epithelium (RPE) in Human Donor Eyes with Age-related Macular Degeneration (AMD)

The hyperglycemia-induced early retinal pigment epithelium dysfunction is mediated by vascular endothelial growth factor

Trichostatin A Rescues RPE Function in Diabetic Rats

Fluorescence and mass spectrometric imaging of monkey ( Cynomolgus) retinal pigment epithelium confirms the mismatching of lipofuscin and A2E distributions observed in human tissue

Components of human lipofuscin

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