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Retinal Cell Biology April 2019

Activation of the BMP4/Smad1 Pathway Promotes Retinal Ganglion Cell Survival and Axon Regeneration

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Adam Thompson; Martin Berry; Ann Logan; Zubair Ahmed
TAGS: rapamycin, peptides, neuronal outgrowth, rna, messenger, retinal ganglion cells, axon, neurites
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1748-1759. doi: 10.1167/iovs.18-26449

Glaucoma November 2018

Mesenchymal Stem Cell–Derived Small Extracellular Vesicles Promote Neuroprotection in a Genetic DBA/2J Mouse Model of Glaucoma

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Ben Mead; Zubair Ahmed; Stanislav Tomarev
TAGS: glaucoma, ocular hypertension, genetics, mice, stem cell, mesenchymal, neuroprotection, exosomes, extracellular vesicles
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5473-5480. doi: 10.1167/iovs.18-25310

Includes: Supplemental Content

Retinal Cell Biology September 2018

Caspase-2 Mediates Site-Specific Retinal Ganglion Cell Death After Blunt Ocular Injury

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Chloe N. Thomas; Adam M. Thompson; Eleanor McCance; Martin Berry; Ann Logan; Richard J. Blanch; Zubair Ahmed
TAGS: caspases, eye injuries, photoreceptors, retinal ganglion cells, wounds and injuries, ocular trauma
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4453-4462. doi: 10.1167/iovs.18-24045

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Early biomarkers of retinal injury in rat optic nerve crush and blunt injury models of ocular trauma.

Adam Morgan Thompson; Chloe Naomi Thomas; Ghazala Begum; Zubair Ahmed; Ann Logan; Richard J Blanch; Martin Berry

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2366. doi:

ARVO Annual Meeting Abstract July 2018

BMSC-derived exosomes promote retinal ganglion cell survival in multiple rodent models of glaucoma

Ben Mead; Juan Amaral; Zubair Ahmed; Stanislav I Tomarev

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2615. doi:

ARVO Annual Meeting Abstract July 2018

Caspase-2 increases in RGC and its inhibition protects against optic nerve degeneration in a murine repeated blast ocular trauma model.

Chloe Naomi Thomas; Tonia S Rex; Alexandra Bernardo-Colon; Richard J Blanch; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4450. doi:

ARVO Annual Meeting Abstract June 2017

Usher Syndrome protein, CIB2, is essential for murine retinal sensory cells maintenance and function

Saumil Sethna; Patrick A Scott; Arnaud Giese; Mary A Johnson; Saima Riazuddin; Steven L Bernstein; Maureen A McCall; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):270. doi:

ARVO Annual Meeting Abstract June 2017

Necroptosis is responsible for RGC but not photoreceptor degeneration after blunt ocular trauma.

Chloe Naomi Thomas; Adam Thompson; Ann Logan; Richard J Blanch; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1759. doi:

ARVO Annual Meeting Abstract June 2017

Variable penetrance of Fraser syndrome-associated FREM2 allele and candidate genetic modifier

Sairah Yousaf; Rehan Sadiq Shaikh; Rehana Iqbal; Saima Riazuddin; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4527. doi:

ARVO Annual Meeting Abstract September 2016

Influence of Risk Alleles for Age-Related Macular Degeneration on Recessive Stargardt Disease Phenotypes

Robert Sisk; Robert B Hufnagel; Brent Zanke; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3164. doi:

ARVO Annual Meeting Abstract September 2016

Survey of ophthalmic and systemic features in patients with PNPLA6 -related disorders

Robert B Hufnagel; Sarah Hull; Jose Luiz Pedroso; Shuan Dai; Andrea Nemeth; Helene Dollfus; Brian Patrick Brooks; Robert Sisk; Michel Michaelides; Anthony T Moore; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6564. doi:

ARVO Annual Meeting Abstract September 2016

The Therapeutic Utility of Decorin Eye Drops for the Prevention of Corneal Scarring

Maryam Esmaeili; Zubair Ahmed; Saaeha Rauz; Liam M. Grover; Ann Logan

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1291. doi:

ARVO Annual Meeting Abstract September 2016

Caspase-2 mediates retinal ganglion cell apoptosis in traumatic optic neuropathy caused by blunt ocular trauma.

Chloe Naomi Thomas; Ann Logan; Zubair Ahmed; Richard J Blanch

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):744. doi:

ARVO Annual Meeting Abstract September 2016

Variable expression of TIMP3 -related maculopathy due to an atypical mutation in a large family

Jerry Lee; Robert Sisk; Courtney Linne; Laura Krueger; Scott Schoenberger; Lars Fritsche; Emily Y Chew; Brian Patrick Brooks; Anita Agarwal; Zubair Ahmed; Robert B Hufnagel

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3145. doi:

ARVO Annual Meeting Abstract September 2016

RhoA-mediated contractility of the trabecular meshwork regulates intraocular pressure in the early but not in the late fibrotic phase of Primary Open Angle Glaucoma

Lisa J Hill; Ben Mead; Felicity de Cogan; Elena Feinstein; Zubair Ahmed; Richard J Blanch; Peter Morgan-Warren; Martin Berry; Ann Logan

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4690. doi:

ARVO Annual Meeting Abstract September 2016

The role of pigment epithelium-derived factor in the progression of primary open angle glaucoma

Richard J Blanch; Lisa J Hill; Jenna O'Neill; Philip Ian Murray; Imran Masood; Ann Logan; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

Visual Psychophysics and Physiological Optics July 2016

Cone Photoreceptor Structure in Patients With X-Linked Cone Dysfunction and Red-Green Color Vision Deficiency

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Emily J. Patterson; Melissa Wilk; Christopher S. Langlo; Melissa Kasilian; Michael Ring; Robert B. Hufnagel; Adam M. Dubis; James J. Tee; Angelos Kalitzeos; Jessica C. Gardner; Zubair M. Ahmed; Robert A. Sisk; Michael Larsen; Stacy Sjoberg; Thomas B. Connor; Alfredo Dubra; Jay Neitz; Alison J. Hardcastle; Maureen Neitz; Michel Michaelides; Joseph Carroll
TAGS: phenotype, color vision defect, retinal cone, mosaicism, x-linked inheritance, pathophysiology
Invest. Ophthalmol. Vis. Sci.. 2016; 57(8):3853-3863. doi: 10.1167/iovs.16-19608

Includes: Supplemental Content

Retinal Cell Biology February 2016

siRNA-Mediated Knockdown of the mTOR Inhibitor RTP801 Promotes Retinal Ganglion Cell Survival and Axon Elongation by Direct and Indirect Mechanisms

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Peter J. Morgan-Warren; Jenna O'Neill; Felicity de Cogan; Igor Spivak; Hagit Ashush; Hagar Kalinski; Zubair Ahmed; Martin Berry; Elena Feinstein; Robert A. H. Scott; Ann Logan
TAGS: rapamycin, axon, glial fibrillary acidic protein, nerve growth factors, neurites, neuroglia, retinal ganglion cells, wounds and injuries, rna, small interfering, mtor inhibitors, intravitreal injections
Invest. Ophthalmol. Vis. Sci.. 2016; 57(2):429-443. doi: 10.1167/iovs.15-17511

Includes: Supplemental Content

Glaucoma June 2015

Decorin Reduces Intraocular Pressure and Retinal Ganglion Cell Loss in Rodents Through Fibrolysis of the Scarred Trabecular Meshwork

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Lisa J. Hill; Ben Mead; Richard J. Blanch; Zubair Ahmed; Felicity De Cogan; Peter J. Morgan-Warren; Shabbir Mohamed; Wendy Leadbeater; Robert A. H. Scott; Martin Berry; Ann Logan
TAGS: immunohistochemistry, fibrosis, cicatrix, injection of therapeutic agent, retinal ganglion cells, rodentia, trabecular meshwork, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2015; 56(6):3743-3757. doi: 10.1167/iovs.14-15622

ARVO Annual Meeting Abstract June 2015

Executioner Caspase Activity and Photoreceptor Apoptosis After Blunt Ocular Trauma

Richard J Blanch; Zubair Ahmed; Adam Morgan Thompson; Nsikan Akpan; david RJ snead; Martin Berry; Carol Troy; Robert A H Scott; Ann Logan

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):6023. doi:

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Activation of the BMP4/Smad1 Pathway Promotes Retinal Ganglion Cell Survival and Axon Regeneration

Mesenchymal Stem Cell–Derived Small Extracellular Vesicles Promote Neuroprotection in a Genetic DBA/2J Mouse Model of Glaucoma

Caspase-2 Mediates Site-Specific Retinal Ganglion Cell Death After Blunt Ocular Injury

Early biomarkers of retinal injury in rat optic nerve crush and blunt injury models of ocular trauma.

BMSC-derived exosomes promote retinal ganglion cell survival in multiple rodent models of glaucoma

Caspase-2 increases in RGC and its inhibition protects against optic nerve degeneration in a murine repeated blast ocular trauma model.

Usher Syndrome protein, CIB2, is essential for murine retinal sensory cells maintenance and function

Necroptosis is responsible for RGC but not photoreceptor degeneration after blunt ocular trauma.

Variable penetrance of Fraser syndrome-associated FREM2 allele and candidate genetic modifier

Influence of Risk Alleles for Age-Related Macular Degeneration on Recessive Stargardt Disease Phenotypes

Survey of ophthalmic and systemic features in patients with PNPLA6 -related disorders

The Therapeutic Utility of Decorin Eye Drops for the Prevention of Corneal Scarring

Caspase-2 mediates retinal ganglion cell apoptosis in traumatic optic neuropathy caused by blunt ocular trauma.

Variable expression of TIMP3 -related maculopathy due to an atypical mutation in a large family

RhoA-mediated contractility of the trabecular meshwork regulates intraocular pressure in the early but not in the late fibrotic phase of Primary Open Angle Glaucoma

The role of pigment epithelium-derived factor in the progression of primary open angle glaucoma

Cone Photoreceptor Structure in Patients With X-Linked Cone Dysfunction and Red-Green Color Vision Deficiency

siRNA-Mediated Knockdown of the mTOR Inhibitor RTP801 Promotes Retinal Ganglion Cell Survival and Axon Elongation by Direct and Indirect Mechanisms

Decorin Reduces Intraocular Pressure and Retinal Ganglion Cell Loss in Rodents Through Fibrolysis of the Scarred Trabecular Meshwork

Executioner Caspase Activity and Photoreceptor Apoptosis After Blunt Ocular Trauma

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