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ARVO Annual Meeting Abstract June 2022

Regulation of Protocadherin-15 function in the outer retina by alternative splicing of cytoplasmic domain

Sehar Riaz; Saumil Sethna; Saima Riazuddin; Livia Carvalho; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1934 – F0352. doi:

ARVO Annual Meeting Abstract June 2022

Title. Development of human retinal pigment epithelial cells with inducible VEGF expression

Inesa Lelyte; Vidhya R. Rao; Zubair Ahmed; Giedrius Kalesnykas; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3608 – A0063. doi:

ARVO Annual Meeting Abstract June 2022

Improving the penetration of Dexamethasone to the posterior segment of eye using topically applied penetration enhancing agents

Abhinav Thareja; Thomas Leigh; Jenni J. Hakkarainen; Carmen Alvarez-Lorenzo; Helen Hughes; Francisco Fernandez-Trillo; Richard J Blanch; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4156 – F0148. doi:

ARVO Annual Meeting Abstract June 2021

PCDH15-associated retinopathy in an orthologous Usher mouse and evaluation of potential therapies for progressive vision loss

Sehar Riaz; Saumil Sethna; Luk H Vandenberghe; Livia Carvalho; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1186. doi:

Visual Neuroscience February 2020

TNFα-Mediated Priming of Mesenchymal Stem Cells Enhances Their Neuroprotective Effect on Retinal Ganglion Cells

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Ben Mead; Xitiz Chamling; Donald J. Zack; Zubair Ahmed; Stanislav Tomarev
TAGS: culture media, conditioned, exosomes, neuroprotection, neuroprotective effect, retinal ganglion cells, stem cell, mesenchymal, cell culture techniques
Invest. Ophthalmol. Vis. Sci.. 2020; 61(2):6. doi: https://doi.org/10.1167/iovs.61.2.6

Retina November 2019

Homozygous Variant in ARL3 Causes Autosomal Recessive Cone Rod Dystrophy

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Shakeel A. Sheikh; Robert A. Sisk; Cara R. Schiavon; Yar M. Waryah; Muhammad A. Usmani; David H. Steel; John A. Sayer; Ashok K. Narsani; Robert B. Hufnagel; Saima Riazuddin; Richard A. Kahn; Ali M. Waryah; Zubair M. Ahmed
TAGS: autosomal recessive inheritance, family, homozygote, mutation, phenotype, progressive cone-rod dystrophy, proteins, retinitis pigmentosa
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4811-4819. doi: https://doi.org/10.1167/iovs.19-27263

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

CIB2 is essential for autophagy in the retinal pigment epithelium and visual function

Zubair Ahmed; Saumil Sethna; Patrick A. Scott; Arnaud P. Giese; Todd Duncan; Sheikh Riazuddin; T Michael Redmond; Steven L Bernstein; Saima Riazuddin

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3868. doi:

ARVO Annual Meeting Abstract July 2019

Necroptosis in a murine repeated primary blast injury model

Chloe Naomi Thomas; Tonia S Rex; Alexandra Bernardo-Colon; Ella Courtie; Gareth Essex; Zubair Ahmed; Richard J Blanch

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4404. doi:

ARVO Annual Meeting Abstract July 2019

Neuroprotection of retinal ganglion cells by BMSC-derived exosomes

Ben Mead; Donald J Zack; Zubair Ahmed; Stanislav I Tomarev

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5174. doi:

Retinal Cell Biology April 2019

Activation of the BMP4/Smad1 Pathway Promotes Retinal Ganglion Cell Survival and Axon Regeneration

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Adam Thompson; Martin Berry; Ann Logan; Zubair Ahmed
TAGS: axon, neurites, neuronal outgrowth, retinal ganglion cells, rapamycin, rna, messenger, peptides
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1748-1759. doi: https://doi.org/10.1167/iovs.18-26449

Glaucoma November 2018

Mesenchymal Stem Cell–Derived Small Extracellular Vesicles Promote Neuroprotection in a Genetic DBA/2J Mouse Model of Glaucoma

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Ben Mead; Zubair Ahmed; Stanislav Tomarev
TAGS: exosomes, glaucoma, mice, neuroprotection, extracellular vesicles, genetics, stem cell, mesenchymal, ocular hypertension
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5473-5480. doi: https://doi.org/10.1167/iovs.18-25310

Includes: Supplemental Content

Retinal Cell Biology September 2018

Caspase-2 Mediates Site-Specific Retinal Ganglion Cell Death After Blunt Ocular Injury

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Chloe N. Thomas; Adam M. Thompson; Eleanor McCance; Martin Berry; Ann Logan; Richard J. Blanch; Zubair Ahmed
TAGS: caspases, eye injuries, wounds and injuries, retinal ganglion cells, photoreceptors, ocular trauma
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4453-4462. doi: https://doi.org/10.1167/iovs.18-24045

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Early biomarkers of retinal injury in rat optic nerve crush and blunt injury models of ocular trauma.

Adam Morgan Thompson; Chloe Naomi Thomas; Ghazala Begum; Zubair Ahmed; Ann Logan; Richard J Blanch; Martin Berry

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2366. doi:

ARVO Annual Meeting Abstract July 2018

BMSC-derived exosomes promote retinal ganglion cell survival in multiple rodent models of glaucoma

Ben Mead; Juan Amaral; Zubair Ahmed; Stanislav I Tomarev

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2615. doi:

ARVO Annual Meeting Abstract July 2018

Caspase-2 increases in RGC and its inhibition protects against optic nerve degeneration in a murine repeated blast ocular trauma model.

Chloe Naomi Thomas; Tonia S Rex; Alexandra Bernardo-Colon; Richard J Blanch; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4450. doi:

ARVO Annual Meeting Abstract June 2017

Usher Syndrome protein, CIB2, is essential for murine retinal sensory cells maintenance and function

Saumil Sethna; Patrick A Scott; Arnaud Giese; Mary A Johnson; Saima Riazuddin; Steven L Bernstein; Maureen A McCall; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):270. doi:

ARVO Annual Meeting Abstract June 2017

Necroptosis is responsible for RGC but not photoreceptor degeneration after blunt ocular trauma.

Chloe Naomi Thomas; Adam Thompson; Ann Logan; Richard J Blanch; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1759. doi:

ARVO Annual Meeting Abstract June 2017

Variable penetrance of Fraser syndrome-associated FREM2 allele and candidate genetic modifier

Sairah Yousaf; Rehan Sadiq Shaikh; Rehana Iqbal; Saima Riazuddin; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4527. doi:

ARVO Annual Meeting Abstract September 2016

Caspase-2 mediates retinal ganglion cell apoptosis in traumatic optic neuropathy caused by blunt ocular trauma.

Chloe Naomi Thomas; Ann Logan; Zubair Ahmed; Richard J Blanch

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):744. doi:

ARVO Annual Meeting Abstract September 2016

Variable expression of TIMP3 -related maculopathy due to an atypical mutation in a large family

Jerry Lee; Robert Sisk; Courtney Linne; Laura Krueger; Scott Schoenberger; Lars Fritsche; Emily Y Chew; Brian Patrick Brooks; Anita Agarwal; Zubair Ahmed; Robert B Hufnagel

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3145. doi:

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Regulation of Protocadherin-15 function in the outer retina by alternative splicing of cytoplasmic domain

Title. Development of human retinal pigment epithelial cells with inducible VEGF expression

Improving the penetration of Dexamethasone to the posterior segment of eye using topically applied penetration enhancing agents

PCDH15-associated retinopathy in an orthologous Usher mouse and evaluation of potential therapies for progressive vision loss

TNFα-Mediated Priming of Mesenchymal Stem Cells Enhances Their Neuroprotective Effect on Retinal Ganglion Cells

Homozygous Variant in ARL3 Causes Autosomal Recessive Cone Rod Dystrophy

CIB2 is essential for autophagy in the retinal pigment epithelium and visual function

Necroptosis in a murine repeated primary blast injury model

Neuroprotection of retinal ganglion cells by BMSC-derived exosomes

Activation of the BMP4/Smad1 Pathway Promotes Retinal Ganglion Cell Survival and Axon Regeneration

Mesenchymal Stem Cell–Derived Small Extracellular Vesicles Promote Neuroprotection in a Genetic DBA/2J Mouse Model of Glaucoma

Caspase-2 Mediates Site-Specific Retinal Ganglion Cell Death After Blunt Ocular Injury

Early biomarkers of retinal injury in rat optic nerve crush and blunt injury models of ocular trauma.

BMSC-derived exosomes promote retinal ganglion cell survival in multiple rodent models of glaucoma

Caspase-2 increases in RGC and its inhibition protects against optic nerve degeneration in a murine repeated blast ocular trauma model.

Usher Syndrome protein, CIB2, is essential for murine retinal sensory cells maintenance and function

Necroptosis is responsible for RGC but not photoreceptor degeneration after blunt ocular trauma.

Variable penetrance of Fraser syndrome-associated FREM2 allele and candidate genetic modifier

Caspase-2 mediates retinal ganglion cell apoptosis in traumatic optic neuropathy caused by blunt ocular trauma.

Variable expression of TIMP3 -related maculopathy due to an atypical mutation in a large family

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