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Visual Neuroscience February 2020

TNFα-Mediated Priming of Mesenchymal Stem Cells Enhances Their Neuroprotective Effect on Retinal Ganglion Cells

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Ben Mead; Xitiz Chamling; Donald J. Zack; Zubair Ahmed; Stanislav Tomarev
TAGS: culture media, conditioned, exosomes, neuroprotection, neuroprotective effect, retinal ganglion cells, stem cell, mesenchymal, cell culture techniques
Invest. Ophthalmol. Vis. Sci.. 2020; 61(2):6. doi: https://doi.org/10.1167/iovs.61.2.6

Retina November 2019

Homozygous Variant in ARL3 Causes Autosomal Recessive Cone Rod Dystrophy

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Shakeel A. Sheikh; Robert A. Sisk; Cara R. Schiavon; Yar M. Waryah; Muhammad A. Usmani; David H. Steel; John A. Sayer; Ashok K. Narsani; Robert B. Hufnagel; Saima Riazuddin; Richard A. Kahn; Ali M. Waryah; Zubair M. Ahmed
TAGS: autosomal recessive inheritance, family, homozygote, mutation, phenotype, progressive cone-rod dystrophy, proteins, retinitis pigmentosa
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4811-4819. doi: https://doi.org/10.1167/iovs.19-27263

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

CIB2 is essential for autophagy in the retinal pigment epithelium and visual function

Zubair Ahmed; Saumil Sethna; Patrick A. Scott; Arnaud P. Giese; Todd Duncan; Sheikh Riazuddin; T Michael Redmond; Steven L Bernstein; Saima Riazuddin

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3868. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Necroptosis in a murine repeated primary blast injury model

Chloe Naomi Thomas; Tonia S Rex; Alexandra Bernardo-Colon; Ella Courtie; Gareth Essex; Zubair Ahmed; Richard J Blanch

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4404. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Neuroprotection of retinal ganglion cells by BMSC-derived exosomes

Ben Mead; Donald J Zack; Zubair Ahmed; Stanislav I Tomarev

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5174. doi: https://doi.org/

Retinal Cell Biology April 2019

Activation of the BMP4/Smad1 Pathway Promotes Retinal Ganglion Cell Survival and Axon Regeneration

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Adam Thompson; Martin Berry; Ann Logan; Zubair Ahmed
TAGS: axon, neurites, neuronal outgrowth, retinal ganglion cells, rapamycin, rna, messenger, peptides
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1748-1759. doi: https://doi.org/10.1167/iovs.18-26449

Glaucoma November 2018

Mesenchymal Stem Cell–Derived Small Extracellular Vesicles Promote Neuroprotection in a Genetic DBA/2J Mouse Model of Glaucoma

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Ben Mead; Zubair Ahmed; Stanislav Tomarev
TAGS: exosomes, glaucoma, mice, neuroprotection, extracellular vesicles, genetics, stem cell, mesenchymal, ocular hypertension
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5473-5480. doi: https://doi.org/10.1167/iovs.18-25310

Includes: Supplemental Content

Retinal Cell Biology September 2018

Caspase-2 Mediates Site-Specific Retinal Ganglion Cell Death After Blunt Ocular Injury

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Chloe N. Thomas; Adam M. Thompson; Eleanor McCance; Martin Berry; Ann Logan; Richard J. Blanch; Zubair Ahmed
TAGS: caspases, eye injuries, wounds and injuries, retinal ganglion cells, photoreceptors, ocular trauma
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4453-4462. doi: https://doi.org/10.1167/iovs.18-24045

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Early biomarkers of retinal injury in rat optic nerve crush and blunt injury models of ocular trauma.

Adam Morgan Thompson; Chloe Naomi Thomas; Ghazala Begum; Zubair Ahmed; Ann Logan; Richard J Blanch; Martin Berry

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2366. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

BMSC-derived exosomes promote retinal ganglion cell survival in multiple rodent models of glaucoma

Ben Mead; Juan Amaral; Zubair Ahmed; Stanislav I Tomarev

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2615. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Caspase-2 increases in RGC and its inhibition protects against optic nerve degeneration in a murine repeated blast ocular trauma model.

Chloe Naomi Thomas; Tonia S Rex; Alexandra Bernardo-Colon; Richard J Blanch; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4450. doi: https://doi.org/

ARVO Annual Meeting Abstract June 2017

Variable penetrance of Fraser syndrome-associated FREM2 allele and candidate genetic modifier

Sairah Yousaf; Rehan Sadiq Shaikh; Rehana Iqbal; Saima Riazuddin; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4527. doi: https://doi.org/

ARVO Annual Meeting Abstract June 2017

Usher Syndrome protein, CIB2, is essential for murine retinal sensory cells maintenance and function

Saumil Sethna; Patrick A Scott; Arnaud Giese; Mary A Johnson; Saima Riazuddin; Steven L Bernstein; Maureen A McCall; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):270. doi: https://doi.org/

ARVO Annual Meeting Abstract June 2017

Necroptosis is responsible for RGC but not photoreceptor degeneration after blunt ocular trauma.

Chloe Naomi Thomas; Adam Thompson; Ann Logan; Richard J Blanch; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1759. doi: https://doi.org/

ARVO Annual Meeting Abstract September 2016

Caspase-2 mediates retinal ganglion cell apoptosis in traumatic optic neuropathy caused by blunt ocular trauma.

Chloe Naomi Thomas; Ann Logan; Zubair Ahmed; Richard J Blanch

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):744. doi: https://doi.org/

ARVO Annual Meeting Abstract September 2016

Variable expression of TIMP3 -related maculopathy due to an atypical mutation in a large family

Jerry Lee; Robert Sisk; Courtney Linne; Laura Krueger; Scott Schoenberger; Lars Fritsche; Emily Y Chew; Brian Patrick Brooks; Anita Agarwal; Zubair Ahmed; Robert B Hufnagel

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3145. doi: https://doi.org/

ARVO Annual Meeting Abstract September 2016

Influence of Risk Alleles for Age-Related Macular Degeneration on Recessive Stargardt Disease Phenotypes

Robert Sisk; Robert B Hufnagel; Brent Zanke; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3164. doi: https://doi.org/

ARVO Annual Meeting Abstract September 2016

RhoA-mediated contractility of the trabecular meshwork regulates intraocular pressure in the early but not in the late fibrotic phase of Primary Open Angle Glaucoma

Lisa J Hill; Ben Mead; Felicity de Cogan; Elena Feinstein; Zubair Ahmed; Richard J Blanch; Peter Morgan-Warren; Martin Berry; Ann Logan

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4690. doi: https://doi.org/

ARVO Annual Meeting Abstract September 2016

The role of pigment epithelium-derived factor in the progression of primary open angle glaucoma

Richard J Blanch; Lisa J Hill; Jenna O'Neill; Philip Ian Murray; Imran Masood; Ann Logan; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi: https://doi.org/

ARVO Annual Meeting Abstract September 2016

Survey of ophthalmic and systemic features in patients with PNPLA6 -related disorders

Robert B Hufnagel; Sarah Hull; Jose Luiz Pedroso; Shuan Dai; Andrea Nemeth; Helene Dollfus; Brian Patrick Brooks; Robert Sisk; Michel Michaelides; Anthony T Moore; Zubair Ahmed

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6564. doi: https://doi.org/

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TNFα-Mediated Priming of Mesenchymal Stem Cells Enhances Their Neuroprotective Effect on Retinal Ganglion Cells

Homozygous Variant in ARL3 Causes Autosomal Recessive Cone Rod Dystrophy

CIB2 is essential for autophagy in the retinal pigment epithelium and visual function

Necroptosis in a murine repeated primary blast injury model

Neuroprotection of retinal ganglion cells by BMSC-derived exosomes

Activation of the BMP4/Smad1 Pathway Promotes Retinal Ganglion Cell Survival and Axon Regeneration

Mesenchymal Stem Cell–Derived Small Extracellular Vesicles Promote Neuroprotection in a Genetic DBA/2J Mouse Model of Glaucoma

Caspase-2 Mediates Site-Specific Retinal Ganglion Cell Death After Blunt Ocular Injury

Early biomarkers of retinal injury in rat optic nerve crush and blunt injury models of ocular trauma.

BMSC-derived exosomes promote retinal ganglion cell survival in multiple rodent models of glaucoma

Caspase-2 increases in RGC and its inhibition protects against optic nerve degeneration in a murine repeated blast ocular trauma model.

Variable penetrance of Fraser syndrome-associated FREM2 allele and candidate genetic modifier

Usher Syndrome protein, CIB2, is essential for murine retinal sensory cells maintenance and function

Necroptosis is responsible for RGC but not photoreceptor degeneration after blunt ocular trauma.

Caspase-2 mediates retinal ganglion cell apoptosis in traumatic optic neuropathy caused by blunt ocular trauma.

Variable expression of TIMP3 -related maculopathy due to an atypical mutation in a large family

Influence of Risk Alleles for Age-Related Macular Degeneration on Recessive Stargardt Disease Phenotypes

RhoA-mediated contractility of the trabecular meshwork regulates intraocular pressure in the early but not in the late fibrotic phase of Primary Open Angle Glaucoma

The role of pigment epithelium-derived factor in the progression of primary open angle glaucoma

Survey of ophthalmic and systemic features in patients with PNPLA6 -related disorders

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