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Clinical and Epidemiologic Research January 2021

Assessment of Choroidal Vascularity and Choriocapillaris Blood Perfusion in Anisomyopic Adults by SS-OCT/OCTA

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Hao Wu; Guoyun Zhang; Meixiao Shen; Renchang Xu; Pengqi Wang; Zhenqi Guan; Zhu Xie; Zi Jin; Sisi Chen; Xinjie Mao; Jia Qu; Xiangtian Zhou

Invest. Ophthalmol. Vis. Sci.. 2021; 62(1):8. doi: https://doi.org/10.1167/iovs.62.1.8

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology December 2020

Interocular Suppression as Revealed by Dichoptic Masking Is Orientation-Dependent and Imbalanced in Amblyopia

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Ling Gong; Alexandre Reynaud; Zili Wang; Suqi Cao; Fan Lu; Jia Qu; Robert F. Hess; Jiawei Zhou

Invest. Ophthalmol. Vis. Sci.. 2020; 61(14):28. doi: https://doi.org/10.1167/iovs.61.14.28

Includes: Supplemental Content

Physiology and Pharmacology November 2020

Increased Choroidal Blood Perfusion Can Inhibit Form Deprivation Myopia in Guinea Pigs

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Xuan Zhou; Sen Zhang; Guoyun Zhang; Yizhong Chen; Yi Lei; Jing Xiang; Renchang Xu; Jia Qu; Xiangtian Zhou

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):25. doi: https://doi.org/10.1167/iovs.61.13.25

Immunology and Microbiology October 2020

Co-Expression of Mitochondrial Genes and ACE2 in Cornea Involved in COVID-19

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Jian Yuan; Dandan Fan; Zhengbo Xue; Jia Qu; Jianzhong Su
TAGS: cornea, covid-19, genes, mitochondria, disease susceptibility
Invest. Ophthalmol. Vis. Sci.. 2020; 61(12):13. doi: https://doi.org/10.1167/iovs.61.12.13

Biochemistry and Molecular Biology July 2020

Crosstalk between EP2 and PPARα Modulates Hypoxic Signaling and Myopia Development in Guinea Pigs

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Nethrajeith Srinivasalu; Sen Zhang; Renchang Xu; Peter Sol Reinach; Yongchao Su; Yun Zhu; Jia Qu; Xiangtian Zhou
TAGS: caviidae, cyclic amp, hypoxia, myopia, ppar alpha, sclera, signal transduction, injections, gene expression
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):44. doi: https://doi.org/10.1167/iovs.61.8.44

Includes: Supplemental Content

Biochemistry and Molecular Biology June 2020

The Role of the Dopamine D2 Receptor in Form-Deprivation Myopia in Mice: Studies With Full and Partial D2 Receptor Agonists and Knockouts

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Furong Huang; Qiongsi Wang; Tingting Yan; Jing Tang; Xueqin Hou; Ziheng Shu; Fen Wan; Yanan Yang; Jia Qu; Xiangtian Zhou
TAGS: agonists, aripiprazole, mice, myopia, quinpirole, dopamine d2 receptor, body weight, cyclic amp, eye
Invest. Ophthalmol. Vis. Sci.. 2020; 61(6):47. doi: https://doi.org/10.1167/iovs.61.6.47

Includes: Supplemental Content

Genetics September 2019

Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients

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Xue-Bi Cai; Yi-Han Zheng; De-Fu Chen; Fang-Yue Zhou; Lu-Qi Xia; Xin-Ran Wen; Yi-Min Yuan; Fang Han; Shun-Yu Piao; Wenjuan Zhuang; Fan Lu; Jia Qu; A-Yong Yu; Zi-Bing Jin
TAGS: chinese (other dialects), chinese people, genotype, myopia, phenotype, refractive errors, retinal diseases, mutation, visual impairment, genes
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):4052-4062. doi: https://doi.org/10.1167/iovs.19-27921

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Scleral macrophages contribute to myopia development via MMP-2 upregulation

Xiangtian Zhou; Fei Zhao; Hao Wu; Li Ma; Yi Wu; Jia Qu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5866. doi:

ARVO Annual Meeting Abstract July 2019

Sclera-specific Hif-1α knockdown attenuates form deprivation myopia (FDM) development in mice

Fei Zhao; Qingyi Zhou; Ying Zhai; Jia Qu; Xiangtian Zhou

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5898. doi:

ARVO Annual Meeting Abstract July 2019

Inverse occlusion, a binocularly motivated treatment for amblyopia

Jiawei Zhou; Yidong Wu; Yiya Chen; Xiaoxin Chen; Yunjie Liang; Yu Mao; Zhimo Yao; Zhifen He; Fan Lu; Jia Qu; Robert Hess

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):214. doi:

ARVO Annual Meeting Abstract July 2019

Drebrin plasma levels elevated with RGCs axonopathy in glaucoma patients

GAN YIJING; ZAILONG CHI; JIA QU

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):681. doi:

ARVO Annual Meeting Abstract July 2019

Corneal collagen cross-linking pretreatment mitigates inflammation, hemangiogenesis and lymphangiogenesis in rats

Wei Chen; Yirui Zhu; Peter Reinach; Jia Qu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):899. doi:

ARVO Annual Meeting Abstract July 2019

Crosstalk between prostanoid receptor (EP2) and peroxisome proliferator-activated receptor (PPAR)-linked cyclic adenosine monophosphate (cAMP) signaling affects myopia in guinea pigs

Nethrajeith Srinivasalu; Sen Zhang; Yang Hu; Xiangtian Zhou; Jia Qu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3151. doi:

Anatomy and Pathology/Oncology July 2019

Changes in Choroidal Thickness and Choroidal Blood Perfusion in Guinea Pig Myopia

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Sen Zhang; Guoyun Zhang; Xuan Zhou; Renchang Xu; Siyao Wang; Zhenqi Guan; Juan Lu; Nethrajeith Srinivasalu; Meixiao Shen; Zi Jin; Jia Qu; Xiangtian Zhou
TAGS: guinea, myopia, perfusion, eye, refraction, dislocations
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3074-3083. doi: https://doi.org/10.1167/iovs.18-26397

Includes: Supplemental Content

Glaucoma February 2019

Parapapillary Choroidal Microvasculature Dropout Is Associated With the Decrease in Retinal Nerve Fiber Layer Thickness: A Prospective Study

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Sigeng Lin; Huanhuan Cheng; Shaodan Zhang; Cong Ye; Xiafei Pan; Aizhu Tao; Xiang Xu; Jia Qu; Yuanbo Liang
TAGS: glaucoma, microvascular network, prospective studies, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):838-842. doi: https://doi.org/10.1167/iovs.18-26115

Biochemistry and Molecular Biology December 2018

Opposing Effects of PPARα Agonism and Antagonism on Refractive Development and Form Deprivation Myopia in Guinea Pigs

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Miaozhen Pan; Shiming Jiao; Peter S. Reinach; Jiaofeng Yan; Yanan Yang; Qihang Li; Nethrajeith Srinivasalu; Jia Qu; Xiangtian Zhou
TAGS: eye, myopia, ppar alpha, bezafibrate, caviidae, injections, apolipoprotein a-ii
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5803-5815. doi: https://doi.org/10.1167/iovs.17-22297

Includes: Supplemental Content

Biochemistry and Molecular Biology November 2018

SIRT1 Deletion Impairs Retinal Endothelial Cell Migration Through Downregulation of VEGF-A/VEGFR-2 and MMP14

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Yong Lin; Li Li; Junjie Liu; Xiaoting Zhao; Juxiu Ye; Peter S. Reinach; Jia Qu; Dongsheng Yan
TAGS: angiogenesis, down-regulation, endothelial cells, mice, vascular endothelial growth factor a, vascular endothelial growth factor receptor-2, western blotting, rna, small interfering
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5431-5440. doi: https://doi.org/10.1167/iovs.17-23558

Includes: Supplemental Content

Articles November 2018

Measuring the Contrast Sensitivity Function Using the qCSF Method With 10 Digits

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Haiyan Zheng; Chenxiao Wang; Rong Cui; Xianghang He; Menglu Shen; Luis Andres Lesmes; Zhong-Lin Lu; Jia Qu; Fang Hou
TAGS: colony-stimulating factors, contrast sensitivity, spatial frequency, precision
Trans. Vis. Sci. Tech.. 2018; 7(6):9. doi: https://doi.org/10.1167/tvst.7.6.9

Biochemistry and Molecular Biology September 2018

Effects of the Tyrosinase-Dependent Dopaminergic System on Refractive Error Development in Guinea Pigs

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Liqin Jiang; Sen Zhang; Rongfang Chen; Li Ma; Xiaojun Wang; Yingying Wen; Jia Qu; Xiangtian Zhou
TAGS: caviidae, dopamine, eye, monophenol monooxygenase, refractive errors, uvea, kojic acid
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4631-4638. doi: https://doi.org/10.1167/iovs.17-22315

Biochemistry and Molecular Biology September 2018

Dopamine Receptor Subtypes Mediate Opposing Effects on Form Deprivation Myopia in Pigmented Guinea Pigs

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Sen Zhang; Jinglei Yang; Peter S. Reinach; Fengjiao Wang; Lishuai Zhang; Miaomiao Fan; Huangfang Ying; Miaozhen Pan; Jia Qu; Xiangtian Zhou
TAGS: caviidae, dopamine receptors, myopia, eye, 3,4-dihydroxyphenylacetic acid, sk&f-38393, refractive errors, quinpirole, sulpiride
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4441-4448. doi: https://doi.org/10.1167/iovs.17-21574

Includes: Supplemental Content

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Assessment of Choroidal Vascularity and Choriocapillaris Blood Perfusion in Anisomyopic Adults by SS-OCT/OCTA

Interocular Suppression as Revealed by Dichoptic Masking Is Orientation-Dependent and Imbalanced in Amblyopia

Increased Choroidal Blood Perfusion Can Inhibit Form Deprivation Myopia in Guinea Pigs

Co-Expression of Mitochondrial Genes and ACE2 in Cornea Involved in COVID-19

Crosstalk between EP2 and PPARα Modulates Hypoxic Signaling and Myopia Development in Guinea Pigs

The Role of the Dopamine D2 Receptor in Form-Deprivation Myopia in Mice: Studies With Full and Partial D2 Receptor Agonists and Knockouts

Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients

Scleral macrophages contribute to myopia development via MMP-2 upregulation

Sclera-specific Hif-1α knockdown attenuates form deprivation myopia (FDM) development in mice

Inverse occlusion, a binocularly motivated treatment for amblyopia

Drebrin plasma levels elevated with RGCs axonopathy in glaucoma patients

Corneal collagen cross-linking pretreatment mitigates inflammation, hemangiogenesis and lymphangiogenesis in rats

Crosstalk between prostanoid receptor (EP2) and peroxisome proliferator-activated receptor (PPAR)-linked cyclic adenosine monophosphate (cAMP) signaling affects myopia in guinea pigs

Changes in Choroidal Thickness and Choroidal Blood Perfusion in Guinea Pig Myopia

Parapapillary Choroidal Microvasculature Dropout Is Associated With the Decrease in Retinal Nerve Fiber Layer Thickness: A Prospective Study

Opposing Effects of PPARα Agonism and Antagonism on Refractive Development and Form Deprivation Myopia in Guinea Pigs

SIRT1 Deletion Impairs Retinal Endothelial Cell Migration Through Downregulation of VEGF-A/VEGFR-2 and MMP14

Measuring the Contrast Sensitivity Function Using the qCSF Method With 10 Digits

Effects of the Tyrosinase-Dependent Dopaminergic System on Refractive Error Development in Guinea Pigs

Dopamine Receptor Subtypes Mediate Opposing Effects on Form Deprivation Myopia in Pigmented Guinea Pigs

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