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Articles August 2020

Hyperglycemia Augments Endothelin-1–Induced Constriction of Human Retinal Venules

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Yen-Lin Chen; Robert H. Rosa, Jr.; Lih Kuo; Travis W. Hein
TAGS: constriction procedure, endothelin-1, hyperglycemia, retinal venule, glucose, suidae
Trans. Vis. Sci. Tech.. 2020; 9(9):1. doi: https://doi.org/10.1167/tvst.9.9.1

Includes: Supplemental Content

Physiology and Pharmacology May 2020

Role of Arginase in Selective Impairment of Endothelium-Dependent Nitric Oxide Synthase-Mediated Dilation of Retinal Arterioles during Early Diabetes

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Travis W. Hein; Tsuneaki Omae; Wenjuan Xu; Akitoshi Yoshida; Lih Kuo
TAGS: arginase, arteriole, diabetes mellitus, dilatation, pathologic, endothelium, nitric oxide, impairment
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):36. doi: https://doi.org/10.1167/iovs.61.5.36

ARVO Annual Meeting Abstract July 2019

Stanniocalcin-1 enhances ellipsoid zone intensity and cone function in the P23H rhodopsin transgenic pig

Wankun Xie; Min Zhao; Shu-Huai Tsai; Maxwell Su; Travis W Hein; Lih Kuo; Robert H Rosa

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):452. doi:

ARVO Annual Meeting Abstract July 2019

Intravitreal stanniocalcin-2 reduces photoreceptor degeneration and improves oscillatory potentials with elevated ocular blood flow in retinitis pigmentosa

Min Zhao; Wankun Xie; Wencong Chen; Travis W Hein; Lih Kuo; Robert H Rosa

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4876. doi:

Physiology and Pharmacology October 2018

Constriction of Retinal Venules to Endothelin-1: Obligatory Roles of ET A Receptors, Extracellular Calcium Entry, and Rho Kinase

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Yen-Lin Chen; Yi Ren; Wenjuan Xu; Robert H. Rosa, Jr; Lih Kuo; Travis W. Hein
TAGS: calcium, constriction procedure, endothelin-1, phosphotransferases, retinal venule, suidae
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5167-5175. doi: https://doi.org/10.1167/iovs.18-25369

ARVO Annual Meeting Abstract July 2018

Stanniocalcin-1 rescues photoreceptor degeneration in a porcine model of retinitis pigmentosa

Wankun Xie; Min Zhao; Shu-Huai Tsai; Maxwell G. Su; Gavin W Roddy; Patrick D. Bradley; Matthew M LaVail; Travis W Hein; Lih Kuo; Robert H Rosa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1008. doi:

ARVO Annual Meeting Abstract July 2018

Stanniocalcin-2 preserves retinal function in a rat model of retinitis pigmentosa

Min Zhao; Wankun Xie; Shu-Huai Tsai; Maxwell G. Su; Travis W Hein; Lih Kuo; Robert H Rosa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):997. doi:

Physiology and Pharmacology February 2018

Intravitreal Stanniocalcin-1 Enhances New Blood Vessel Growth in a Rat Model of Laser-Induced Choroidal Neovascularization

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Min Zhao; Wankun Xie; Shu-Huai Tsai; Travis W. Hein; Brent A. Rocke; Lih Kuo; Robert H. Rosa, Jr
TAGS: choroidal neovascularization, lasers
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):1125-1133. doi: https://doi.org/10.1167/iovs.17-23083

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Progression of photoreceptor degeneration in a porcine model of retinitis pigmentosa

Wankun Xie; Min Zhao; Shu-Huai Tsai; Travis W Hein; Lih Kuo; Robert H Rosa

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):274. doi:

ARVO Annual Meeting Abstract June 2017

Correlation of Fundus Autofluorescence and Histology of Laser-induced Choroidal Neovascularization in the Rat

Min Zhao; Wankun Xie; Shu-Huai Tsai; Brent A. Rocke; Travis W Hein; Lih Kuo; Robert H Rosa

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2310. doi:

ARVO Annual Meeting Abstract June 2017

Alteration of ocular blood pressure and flow leads to ophthalmic vascular and neuroretinal dysfunction

Shu-Huai Tsai; Wankun Xie; Min Zhao; Robert H Rosa; Travis W Hein; Lih Kuo

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3029. doi:

ARVO Annual Meeting Abstract June 2017

Acute and Chronic Hyperglycemia Enhance Constriction of Retinal Venules to Endothelin-1

Yen-Lin Chen; Wenjuan Xu; Lih Kuo; Travis W. Hein

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5800. doi:

ARVO Annual Meeting Abstract September 2016

Correlation of spectral domain optical coherence tomography and histology in the porcine retina

Wankun Xie; Min Zhao; Shu-Huai Tsai; William Burkes; Yi Ren; Wenjuan Xu; Christina Du; Travis W Hein; Lih Kuo; Robert H Rosa

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2197. doi:

ARVO Annual Meeting Abstract September 2016

Intravitreal Stanniocalcin-1 enhances new blood vessel growth in a rat model of laser-induced choroidal neovascularization

Min Zhao; Wankun Xie; Shu-Huai Tsai; Yi Ren; Travis W Hein; Lih Kuo; Robert H Rosa

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4519. doi:

ARVO Annual Meeting Abstract September 2016

Arterial hypertension induces ocular vascular dysfunction in mice with pressure-overload cardiac hypertrophy

Shu-Huai Tsai; Wankun Xie; Min Zhao; Robert H Rosa; Travis W Hein; Lih Kuo

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4629. doi:

Retina September 2016

Histamine-Induced Dilation of Isolated Porcine Retinal Arterioles: Role of Endothelium-Derived Hyperpolarizing Factor

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Shinichi Otani; Taiji Nagaoka; Tsuneaki Omae; Ichiro Tanano; Takayuki Kamiya; Shinji Ono; Travis W. Hein; Lih Kuo; Akitoshi Yoshida

Invest. Ophthalmol. Vis. Sci.. 2016; 57(11):4791-4798. doi: https://doi.org/10.1167/iovs.15-19038

Physiology and Pharmacology August 2016

Acute and Chronic Hyperglycemia Elicit JIP1/JNK-Mediated Endothelial Vasodilator Dysfunction of Retinal Arterioles

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Travis W. Hein; Wenjuan Xu; Xin Xu; Lih Kuo

Invest. Ophthalmol. Vis. Sci.. 2016; 57(10):4333-4340. doi: https://doi.org/10.1167/iovs.16-19990

Physiology and Pharmacology August 2015

VEGF Receptor-2–Linked PI3K/Calpain/SIRT1 Activation Mediates Retinal Arteriolar Dilations to VEGF and Shear Stress

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Travis W. Hein; Robert H. Rosa, Jr; Yi Ren; Wenjuan Xu; Lih Kuo
TAGS: 1-phosphatidylinositol 3-kinase, arteriole, calpain, dilatation, pathologic, endothelium, fluid flow, phosphoinositide 3-kinase, shear stress, vascular endothelial growth factor a, vascular endothelial growth factor receptor-2
Invest. Ophthalmol. Vis. Sci.. 2015; 56(9):5381-5389. doi: https://doi.org/10.1167/iovs15-16950

ARVO Annual Meeting Abstract June 2015

Arterial hypertension induces retinal degeneration in mice with pressure-overload cardiac hypertrophy

Shu-Huai Tsai; Wankun Xie; Robert H Rosa; Travis W Hein; Lih Kuo

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4862. doi:

ARVO Annual Meeting Abstract June 2015

In vivo correlation of retinal morphological and functional changes in a porcine model of inherited retinal degeneration

Wankun Xie; Gavin W Roddy; Patrick D. Bradley; Shu-Huai Tsai; Luke B Potts; Wenjuan Xu; Christina Du; Travis W Hein; Lih Kuo; Robert H Rosa

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5399. doi:

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Hyperglycemia Augments Endothelin-1–Induced Constriction of Human Retinal Venules

Role of Arginase in Selective Impairment of Endothelium-Dependent Nitric Oxide Synthase-Mediated Dilation of Retinal Arterioles during Early Diabetes

Stanniocalcin-1 enhances ellipsoid zone intensity and cone function in the P23H rhodopsin transgenic pig

Intravitreal stanniocalcin-2 reduces photoreceptor degeneration and improves oscillatory potentials with elevated ocular blood flow in retinitis pigmentosa

Constriction of Retinal Venules to Endothelin-1: Obligatory Roles of ET A Receptors, Extracellular Calcium Entry, and Rho Kinase

Stanniocalcin-1 rescues photoreceptor degeneration in a porcine model of retinitis pigmentosa

Stanniocalcin-2 preserves retinal function in a rat model of retinitis pigmentosa

Intravitreal Stanniocalcin-1 Enhances New Blood Vessel Growth in a Rat Model of Laser-Induced Choroidal Neovascularization

Progression of photoreceptor degeneration in a porcine model of retinitis pigmentosa

Correlation of Fundus Autofluorescence and Histology of Laser-induced Choroidal Neovascularization in the Rat

Alteration of ocular blood pressure and flow leads to ophthalmic vascular and neuroretinal dysfunction

Acute and Chronic Hyperglycemia Enhance Constriction of Retinal Venules to Endothelin-1

Correlation of spectral domain optical coherence tomography and histology in the porcine retina

Intravitreal Stanniocalcin-1 enhances new blood vessel growth in a rat model of laser-induced choroidal neovascularization

Arterial hypertension induces ocular vascular dysfunction in mice with pressure-overload cardiac hypertrophy

Histamine-Induced Dilation of Isolated Porcine Retinal Arterioles: Role of Endothelium-Derived Hyperpolarizing Factor

Acute and Chronic Hyperglycemia Elicit JIP1/JNK-Mediated Endothelial Vasodilator Dysfunction of Retinal Arterioles

VEGF Receptor-2–Linked PI3K/Calpain/SIRT1 Activation Mediates Retinal Arteriolar Dilations to VEGF and Shear Stress

Arterial hypertension induces retinal degeneration in mice with pressure-overload cardiac hypertrophy

In vivo correlation of retinal morphological and functional changes in a porcine model of inherited retinal degeneration

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