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ARVO Annual Meeting Abstract June 2020

Sex determines the off-target effects of Bevacizumab (Avastin) in mouse models

Dionne Argyle; Felipe Pereira; Ivana Apicella; Nagaraj Kerur; Jayakrishna Ambati; Bradley Gelfand

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4346. doi:

ARVO Annual Meeting Abstract June 2020

Voluntary exercise attenuates choroidal neovascularization in mice

Ryan Daniel Makin; Dionne Argyle; Yosuke Nagasaka; Shuichiro Hirahara; Nagaraj Kerur; Jayakrishna Ambati; Bradley Gelfand

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5392. doi:

ARVO Annual Meeting Abstract June 2020

Alu RNA exacerbates experimental choroidal neovascularization via an inflammasome-dependent pathway

Felipe Pereira; Ivana Apicella; Ryan Makin; Younghee Kim; Charles Wright; Tetsuhiro Yasuma; Reo Yasuma; Shuichiro Hirahara; Shinichi Fukuda; Siddharth Narendran; Romulo Albuquerque; Benjamin Fowler; Nagaraj Kerur; Jayakrishna Ambati; Bradley Gelfand

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5394. doi:

Retinal Cell Biology May 2020

Voluntary Exercise Suppresses Choroidal Neovascularization in Mice

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Ryan D. Makin; Dionne Argyle; Shuichiro Hirahara; Yosuke Nagasaka; Mei Zhang; Zhen Yan; Nagaraj Kerur; Jayakrishna Ambati; Bradley D. Gelfand
TAGS: choroidal neovascularization, exercise, mice
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):52. doi: https://doi.org/10.1167/iovs.61.5.52

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ARVO Annual Meeting Abstract July 2019

Title: Soluble oligomeric Amyloid-β induced retinal pigment epithelial degeneration requires non-canonical inflammsome activation

Siddharth Narendran; DAIPAYAN BANERJEE; Ivana Apicella; Shaobin Wang; Akhil Varshney; Shinichi Fukuda; Nagaraj Kerur; Bradley Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):990. doi:

ARVO Annual Meeting Abstract July 2019

TELOMERASE IN CHOROIDAL NEOVASCULARIZATION

Nagaraj Kerur; Jayakrishna Ambati; Shaobin Wang; DAIPAYAN BANERJEE; Shuichiro Hirahara; Eric Odermatt

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4319. doi:

ARVO Annual Meeting Abstract July 2019

Multifarious evidence for NLRP3 inflammasome expression and activation in retinal pigment epithelium

Ivana Apicella; Shinichi Fukuda; Shuichiro Hirahara; Shaobin Wang; Siddharth Narendran; Nagaraj Kerur; Bradley Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):765. doi:

Retinal Cell Biology December 2018

RF/6A Chorioretinal Cells Do Not Display Key Endothelial Phenotypes

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Ryan D. Makin; Ivana Apicella; Yosuke Nagasaka; Hiroki Kaneko; Stephen D. Turner; Nagaraj Kerur; Jayakrishna Ambati; Bradley D. Gelfand
TAGS: endothelial cells, endothelium, phenotype
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5795-5802. doi: https://doi.org/10.1167/iovs.18-25215

ARVO Annual Meeting Abstract July 2018

Non-integrated, reverse transcribed Alu complementary DNAs in Geographic Atrophy cause RPE toxicity

Shinichi Fukuda; Benjamin J Fowler; Tetsuhiro Yasuma; Akhil Varshney; Kameshwari Ambati; Nagaraj Kerur; Bradley Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2456. doi:

ARVO Annual Meeting Abstract July 2018

Nucleoside reverse transcriptase inhibitors are broad-spectrum RPE protectants

Shuichiro Hirahara; Shinichi Fukuda; Younghee Kim; Reo Yasuma; Kameshwari Ambati; Junichi Fukuhara; Dongxu Fu; DAIPAYAN BANERJEE; Benjamin J Fowler; Tetsuhiro Yasuma; Nagaraj Kerur; Bradley Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2459. doi:

ARVO Annual Meeting Abstract July 2018

Nucleoside reverse transcriptase inhibitors (NRTI) prevent inflammasome activation in retinal pigmented epithelium cells.

DAIPAYAN BANERJEE; Junichi Fukuhara; Dongxu Fu; Shinichi Fukuda; Shuichiro Hirahara; Younghee Kim; Benjamin J Fowler; Tetsuhiro Yasuma; Reo Yasuma; Kameshwari Ambati; Nagaraj Kerur; Bradley Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2475. doi:

ARVO Annual Meeting Abstract June 2017

Endogenous complementary DNA in age-related macular degeneration

Shinichi Fukuda; Tetsuhiro Yasuma; Benjamin J Fowler; Bradley D Gelfand; Nagaraj Kerur; Reo Yasuma; Brian Werner; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5262. doi:

ARVO Annual Meeting Abstract September 2016

Non-canonical NLRP3 Inflammasome activation in Geographic Atrophy

Nagaraj Kerur; Younghee Kim; Shinichi Fukuda; Reo Yasuma; Ana Bastos-Carvalho; Daipayan Banerjee; Benjamin Fowler; Tetsuhiro Yasuma; Bradley D Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):486. doi:

ARVO Annual Meeting Abstract September 2016

Role of interferon signaling in Alu RNA-induced AMD

Daipayan Banerjee; Younghee Kim; Shinichi Fukuda; Reo Yasuma; Ana Bastos-Carvalho; Benjamin Fowler; Tetsuhiro Yasuma; Bradley D Gelfand; Nagaraj Kerur; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):487. doi:

ARVO Annual Meeting Abstract September 2016

Subcutaneous IL-18 administration does not inhibit laser CNV in mice

Tetsuhiro Yasuma; Reo Yasuma; Bradley D Gelfand; Nagaraj Kerur; Ana Bastos-Carvalho; Younghee Kim; Charles B Wright; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4518. doi:

ARVO Annual Meeting Abstract September 2016

Nucleoside reverse transcriptase inhibitors prevent iron-induced retinal pigment epithelium cell death

Junichi Fukuhara; Younghee Kim; Tetsuhiro Yasuma; Reo Yasuma; Benjamin Fowler; Shinichi Fukuda; Takako Fukuhara; Nagaraj Kerur; Bradley D Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5005. doi:

ARVO Annual Meeting Abstract September 2016

Nucleoside reverse transcriptase inhibitors are anti-inflammatory and inhibit poly I:C-induced retinal pigment epithelium degeneration

Shinichi Fukuda; Junichi Fukuhara; Younghee Kim; Benjamin Fowler; Tetsuhiro Yasuma; Reo Yasuma; Takako Fukuhara; Nagaraj Kerur; Bradley D Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6551. doi:

ARVO Annual Meeting Abstract September 2016

Nucleoside reverse transcriptase inhibitors attenuate amyloid-beta-induced retinal pigment epithelium degeneration

Takako Fukuhara; Junichi Fukuhara; Younghee Kim; Tetsuhiro Yasuma; Reo Yasuma; Benjamin Fowler; Shinichi Fukuda; Nagaraj Kerur; Bradley D Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6552. doi:

ARVO Annual Meeting Abstract April 2014

The Fc fragments of Bevacizumab or IVIG suppress choroidal neovascularization

shengjian li; Nagaraj Kerur; Sasha Bogdanovich; Reo Yasuma; Younghee Kim; Takeshi Mizutani; Ana Bastos-Carvalho; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1191. doi:

ARVO Annual Meeting Abstract April 2014

Dideoxy-nucleosides are anti-inflammatory and inhibit RPE degeneration independent of reverse transcriptase inhibition

Benjamin Fowler; Younghee Kim; Yoshio Hirano; Nagaraj Kerur; Valeria Tarallo; Bradley D Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1735. doi:

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Sex determines the off-target effects of Bevacizumab (Avastin) in mouse models

Voluntary exercise attenuates choroidal neovascularization in mice

Alu RNA exacerbates experimental choroidal neovascularization via an inflammasome-dependent pathway

Voluntary Exercise Suppresses Choroidal Neovascularization in Mice

Title: Soluble oligomeric Amyloid-β induced retinal pigment epithelial degeneration requires non-canonical inflammsome activation

TELOMERASE IN CHOROIDAL NEOVASCULARIZATION

Multifarious evidence for NLRP3 inflammasome expression and activation in retinal pigment epithelium

RF/6A Chorioretinal Cells Do Not Display Key Endothelial Phenotypes

Non-integrated, reverse transcribed Alu complementary DNAs in Geographic Atrophy cause RPE toxicity

Nucleoside reverse transcriptase inhibitors are broad-spectrum RPE protectants

Nucleoside reverse transcriptase inhibitors (NRTI) prevent inflammasome activation in retinal pigmented epithelium cells.

Endogenous complementary DNA in age-related macular degeneration

Non-canonical NLRP3 Inflammasome activation in Geographic Atrophy

Role of interferon signaling in Alu RNA-induced AMD

Subcutaneous IL-18 administration does not inhibit laser CNV in mice

Nucleoside reverse transcriptase inhibitors prevent iron-induced retinal pigment epithelium cell death

Nucleoside reverse transcriptase inhibitors are anti-inflammatory and inhibit poly I:C-induced retinal pigment epithelium degeneration

Nucleoside reverse transcriptase inhibitors attenuate amyloid-beta-induced retinal pigment epithelium degeneration

The Fc fragments of Bevacizumab or IVIG suppress choroidal neovascularization

Dideoxy-nucleosides are anti-inflammatory and inhibit RPE degeneration independent of reverse transcriptase inhibition

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