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Meeting Abstract (12)
Journal Articles (1)

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Investigative Ophthalmology & Visual Science (13)

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ARVO Annual Meeting Abstract (12)
Retina (1)

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Eye Anatomy and Disorders (1)
Genetics (1)
Retina (1)

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buffers (1)
cytomegalovirus infections (1)
disease vectors (1)
equine infectious anemia virus (1)
eye (1)
gene transfer techniques (1)
lentiviral vector (1)
macaca (1)
oryctolagus cuniculus (1)
photoreceptors (1)

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ARVO Annual Meeting Abstract June 2020

Neutralising antibody responses to intravitreally delivered AAV2 and exosome-associated AAV2 vectors are associated with a failure of repeated gene transfer following vector readministration in the ipsilateral eye

Michael Whitehead; Andrew Osborne; Peter Widdowson; Patrick Yu-Wai-Man; Keith R Martin

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2441. doi:

ARVO Annual Meeting Abstract July 2018

Tau dysfunction in glaucoma: modulation of optic nerve axonal transport via gene therapy

Tasneem Khatib; Andrew Osborne; Peter S Widdowson; Keith R Martin

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3716. doi:

ARVO Annual Meeting Abstract July 2018

QTA020V, a novel rAAV2 vector, reduces retinal ganglion cell body and axon loss in rats with laser-induced intraocular pressure elevation

Peter S Widdowson; Andrew Osborne; Tasneem Khatib; Katie Hall; Keith R Martin

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6132. doi:

ARVO Annual Meeting Abstract July 2018

Sustained up-regulation of neuroprotective intracellular signalling pathways in retinal ganglion cells following intravitreal injection of QTA020V, a novel rAAV2 vector

Andrew Osborne; Lalana Songra; Peter S Widdowson; Keith R Martin

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6133. doi:

ARVO Annual Meeting Abstract June 2017

Transgene expression, processing and activity following intravitreal Injection of QTA020V, a novel rAAV2 vector for retinal ganglion cell neuroprotection

Andrew Osborne; Peter S Widdowson; Keith R Martin

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2568. doi:

ARVO Annual Meeting Abstract June 2017

Design and characterisation of an AAV2 vector aiming to achieve long term modulation of BDNF signalling as a treatment for glaucoma

Peter S Widdowson; Andrew Osborne; Alessia Tassoni; Keith R Martin

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2569. doi:

ARVO Annual Meeting Abstract June 2017

QTA020V, a novel rAAV2 vector, delays retinal ganglion cell loss following optic nerve crush in the mouse

Keith R Martin; Andrew Osborne; Tasneem Khatib; Amanda Barber; George Kong; Peter S Widdowson

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2954. doi:

Retina June 2013

Transduction of Photoreceptors With Equine Infectious Anemia Virus Lentiviral Vectors: Safety and Biodistribution of StarGen for Stargardt Disease

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Katie Binley; Peter Widdowson; Julie Loader; Michelle Kelleher; Sharifah Iqball; Georgina Ferrige; Jackie de Belin; Marie Carlucci; Diana Angell-Manning; Felicity Hurst; Scott Ellis; James Miskin; Alcides Fernandes; Paul Wong; Rando Allikmets; Christopher Bergstrom; Thomas Aaberg; Jiong Yan; Jian Kong; Peter Gouras; Annick Prefontaine; Mark Vezina; Martin Bussieres; Stuart Naylor; Kyriacos A. Mitrophanous
TAGS: disease vectors, equine infectious anemia virus, eye, gene transfer techniques, lentiviral vector, macaca, oryctolagus cuniculus, photoreceptors, safety, spatial vectors
Invest. Ophthalmol. Vis. Sci.. 2013; 54(6):4061-4071. doi: https://doi.org/10.1167/iovs.13-11871

ARVO Annual Meeting Abstract April 2011

Efficacy, Safety And Tolerability Of StargenTM, A Lentiviral-vector Based Gene Therapy For The Treatment Of Stargardt Disease, In Rabbits And Macaques

Peter Widdowson; Scott Ellis; Katie Binley; Martin Bussières; Annick Prefontaine; Mark Vezina; Rando Allikmets; Jian Kong; Kyriacos Mitrophanous; Stuart Naylor

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):479. doi:

ARVO Annual Meeting Abstract April 2011

Biodistribution and Immunological Response of the Subretinally Injected Lentiviral-Vector StarGenTM in Rabbits and Macaques

Graham Price; Jackie de Belin; Julie Loader; Michelle Kelleher; James Miskin; Georgina Ferrige; Marie Carlucci; Diana Angell-Manning; Stuart Naylor; Peter Widdowson

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):482. doi:

ARVO Annual Meeting Abstract April 2011

Biodistribution and Immunological Responses to the Lentiviral-Vector Based Gene Therapy Product RetinoStat® Following Subretinal Injection in Rabbits and Rhesus Macaques

Stuart M. Naylor; Michelle Kelleher; Julie Loader; Jackie de Belin; James Miskin; Georgina Ferrige; Marie Carlucci; Margaret Esapa; Scott Ellis; Peter Widdowson

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):484. doi:

ARVO Annual Meeting Abstract April 2011

Safety And Tolerability Of Retinostat®, A Lentiviral-vector Based Gene Therapy Product For The Treatment Of Wet Age-related Macular Degeneration, In Rabbits And Monkeys

Scott Ellis; Peter Widdowson; Katie Binley; T. Michael Nork; Paul Miller; Vlad Bantseev; Brian Christian; Kyriacos Mitrophanous; Stuart Naylor

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):488. doi:

ARVO Annual Meeting Abstract April 2011

Subretinal Delivery Of Eiav-based Lentiviral Vectors In The Shaker1 Mouse Model For Usher Syndrometype 1b : Development Of Ushstat®

Marisa L. Zallocchi; Katie Binely; Yatish Lad; Scott Ellis; Peter Widdowson; Kyri Mitrophanous; You-Wei Peng; Linda Cheung; Dominic Cosgrove

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):489. doi:

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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Copyright © 2015 Association for Research in Vision and Ophthalmology.

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