Clinical and Epidemiologic Research

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Clinical and Epidemiologic Research September 2019

Effect of Anesthesia on Intraocular Pressure Measured With Continuous Wireless Telemetry in Nonhuman Primates

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Jessica V. Jasien; Christopher A. Girkin; J. Crawford Downs
TAGS: intraocular pressure, primates, telemetry, wireless technology, ketamine, dexmedetomidine, xylazine
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3830-3834. doi: 10.1167/iovs.19-27758

Clinical and Epidemiologic Research August 2019

Ocular Axial Length and Diabetic Retinopathy: The Kailuan Eye Study

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Qian Wang; Ya Xing Wang; Shou Ling Wu; Shuo Hua Chen; Yan Ni Yan; Mo Chi Yang; Jing Yan Yang; Wen Jia Zhou; Szy Yann Chan; Xiao Hui Zhang; Xuan Yang; Ya Hui Lei; Shu Qi Qin; Meng Xi Chen; Jost B. Jonas; Wen Bin Wei
TAGS: axial length, eye, diabetic retinopathy, eye, diabetes mellitus, diabetes mellitus, type 2, mass or substance concentration per volume, prevalence
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3689-3695. doi: 10.1167/iovs.19-27531

Clinical and Epidemiologic Research August 2019

Visual Function and Functional Decline in Patients With Waterclefts

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Naoki Tanimura; Natsuko Hatsusaka; Hisanori Miyashita; Teppei Shibata; Hidetoshi Ishida; Akane Kunisho; Eri Kubo; Hiroshi Sasaki
TAGS: vision, developmental venous anomaly, cerebral, eye, lens (device)
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3652-3658. doi: 10.1167/iovs.19-26793

Clinical and Epidemiologic Research August 2019

Diabetic Optic Neuropathy and Its Risk Factors in Chinese Patients With Diabetic Retinopathy

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Rui Hua; Lihang Qu; Bing Ma; Peishi Yang; Hao Sun; Limin Liu
TAGS: diabetes mellitus, diabetic retinopathy, optic nerve disorders, risk factors, chinese (other dialects), china, chinese people
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3514-3519. doi: 10.1167/iovs.19-26825

Clinical and Epidemiologic Research August 2019

Increased Nonexudative Age-Related Macular Degeneration Diagnosis Among Medicare Beneficiaries With Rheumatoid Arthritis

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Gloriane Schnabolk; Bärbel Rohrer; Kit N. Simpson
TAGS: age-related macular degeneration, nonexudative, medicare, rheumatoid arthritis, survival analysis, cohort studies, tumor necrosis factors
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3520-3526. doi: 10.1167/iovs.18-26444

Includes: Supplemental Content

Clinical and Epidemiologic Research August 2019

Role of Parental Refractive Status in Myopia Progression: 12-Year Annual Observation From the Guangzhou Twin Eye Study

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Chimei Liao; Xiaohu Ding; Xiaotong Han; Yu Jiang; Jian Zhang; Jane Scheetz; Mingguang He
TAGS: eye, myopia, parent, twins, child
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3499-3506. doi: 10.1167/iovs.19-27164

Includes: Supplemental Content

Clinical and Epidemiologic Research July 2019

Longitudinal Changes in Spherical Equivalent of Moderate to High Hyperopia: 2- to 8-Year Follow-Up of Children at an Initial Age of 5.5 to 8.4 Years

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Yin Hu; Xiaohu Ding; Junwen Zeng; Dongmei Cui; Cong Li; Mingguang He; Xiao Yang
TAGS: child, follow-up, hyperopia, refraction, school-age child, refractive errors, eye
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3127-3134. doi: 10.1167/iovs.18-26435

Clinical and Epidemiologic Research July 2019

Impact of the Morphologic Characteristics of Optic Disc on Choroidal Thickness in Young Myopic Patients

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Qiuying Chen; Jiangnan He; Yao Yin; Hongfeng Zhou; Huifen Jiang; Jianfeng Zhu; Kyoko Ohno-Matsui; Haidong Zou; Ying Fan; Xun Xu
TAGS: myopia, optic disk, tilted optic disc, atrophy
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2958-2967. doi: 10.1167/iovs.18-26393

Clinical and Epidemiologic Research July 2019

Placental CpG Methylation of Inflammation, Angiogenic, and Neurotrophic Genes and Retinopathy of Prematurity

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Catherine M. Bulka; Olaf Dammann; Hudson P. Santos, Jr; Deborah K. VanderVeen; Lisa Smeester; Raina Fichorova; T. Michael O'Shea; Rebecca C. Fry
TAGS: angiogenesis, genes, inflammation, methylation, placenta, retinopathy of prematurity, newborn
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2888-2894. doi: 10.1167/iovs.18-26466

Clinical and Epidemiologic Research July 2019

Trends in the Prevalence of Myopia and Myopic Maculopathy in a Japanese Population: The Hisayama Study

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Emi Ueda; Miho Yasuda; Kohta Fujiwara; Sawako Hashimoto; Kyoko Ohno-Matsui; Jun Hata; Tatsuro Ishibashi; Toshiharu Ninomiya; Koh-Hei Sonoda
TAGS: japanese, macular disorders, myopia, prevalence, trend
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2781-2786. doi: 10.1167/iovs.19-26580

Includes: Supplemental Content

Clinical and Epidemiologic Research June 2019

Overt Proteinuria, Moderately Reduced eGFR and Their Combination Are Predictive of Severe Diabetic Retinopathy or Diabetic Macular Edema in Diabetes

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Masahiko Yamamoto; Kazuya Fujihara; Masahiro Ishizawa; Taeko Osawa; Masanori Kaneko; Hajime Ishiguro; Yasuhiro Matsubayashi; Hiroyasu Seida; Nauta Yamanaka; Shiro Tanaka; Satoru Kodama; Hiruma Hasebe; Hirohito Sone
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, eye diseases, macular edema, diabetic, proteinuria, renal function
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2685-2689. doi: 10.1167/iovs.19-26749

Clinical and Epidemiologic Research June 2019

Size and Shape of Bruch's Membrane Opening in Relationship to Axial Length, Gamma Zone, and Macular Bruch's Membrane Defects

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Qi Zhang; Liang Xu; Wen Bin Wei; Ya Xing Wang; Jost B. Jonas
TAGS: bruch's basal membrane, diameter, eye, shape, beijing, optic disk, hypertrophy
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2591-2598. doi: 10.1167/iovs.19-27331

Clinical and Epidemiologic Research June 2019

Subfoveal Choroidal Thickness, Cardiovascular History, and Risk Factors in the Elderly: The Montrachet Study

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Louis Arnould; Alassane Seydou; Pierre-Henry Gabrielle; Charles Guenancia; Christophe Tzourio; Abderrahmane Bourredjem; Youssef El Alami; Vincent Daien; Christine Binquet; Alain Marie Bron; Catherine Creuzot-Garcher
TAGS: cardiovascular disease risk factors, risk factors, medical history, elderly
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2431-2437. doi: 10.1167/iovs.18-26488

Cornea May 2019

Human Meibum Cholesteryl and Wax Ester Variability With Age, Sex, and Meibomian Gland Dysfunction

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Douglas Borchman; Aparna Ramasubramanian; Gary N. Foulks
TAGS: cohort studies, dry eye syndromes, esters, meibomian gland, lipids, molar tooth, vibration, pathophysiology, donors
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2286-2293. doi: 10.1167/iovs.19-26812

Clinical and Epidemiologic Research May 2019

Factors Associated With Retinal Vessel Diameters in an Elderly Population: the Thessaloniki Eye Study

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Nikolaos Dervenis; Anne L. Coleman; Alon Harris; M. Roy Wilson; Fei Yu; Eleftherios Anastasopoulos; Panayiota Founti; Theofanis Pappas; Vassilis Kilintzis; Fotis Topouzis
TAGS: cardiovascular diseases, glaucoma, retinal vessels, eye, medical history, elderly
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2208-2217. doi: 10.1167/iovs.18-26276

Clinical and Epidemiologic Research May 2019

Vitreomacular Interface Abnormalities and Glaucoma in an Elderly Population (The MONTRACHET Study)

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Julie Blanc; Alassane Seydou; Inès Ben Ghezala; Clémence Deschasse; Cyril Meillon; Alain M. Bron; Christine Binquet; Catherine Creuzot-Garcher
TAGS: glaucoma, elderly
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):1996-2002. doi: 10.1167/iovs.18-26510

Includes: Supplemental Content

Clinical and Epidemiologic Research April 2019

InflammAging at Ocular Surface: Clinical and Biomolecular Analyses in Healthy Volunteers

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Antonio Di Zazzo; Alessandra Micera; Marco Coassin; Giuseppe Varacalli; William Foulsham; Maria De Piano; Stefano Bonini
TAGS: polymerase chain reaction, fluorescent antibody technique, intercellular adhesion molecule 1, middle-aged adult, signs and symptoms, voluntary workers, inflammation, tear film finding
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1769-1775. doi: 10.1167/iovs.18-25822

Includes: Supplemental Content

Clinical and Epidemiologic Research April 2019

Retinal Layer Thicknesses in Early Age-Related Macular Degeneration: Results From the German AugUR Study

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Caroline Brandl; Christiane Brücklmayer; Felix Günther; Martina E. Zimmermann; Helmut Küchenhoff; Horst Helbig; Bernhard H. F. Weber; Iris M. Heid; Klaus J. Stark
TAGS: sample size, biological response modifiers, color, photoreceptors, reference values, software, diagnostic imaging, eye, age-related macular degeneration, reliability
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1581-1594. doi: 10.1167/iovs.18-25332

Includes: Supplemental Content

Clinical and Epidemiologic Research April 2019

The Common Antidiabetic Drug Metformin Reduces Odds of Developing Age-Related Macular Degeneration

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Emily E. Brown; Jacob D. Ball; Zhaoyi Chen; Gibran S. Khurshid; Mattia Prosperi; John D. Ash
TAGS: metformin, age-related macular degeneration, antidiabetics
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1470-1477. doi: 10.1167/iovs.18-26422

Clinical and Epidemiologic Research April 2019

Small Hard Macular Drusen and Associations in 11- to 12-Year-Old Children in the Copenhagen Child Cohort 2000 Eye Study

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Inger Christine Munch; Xiao Qiang Li; Shaista Sumbal Mulk Ahmad; Else Marie Olsen; Anne Mette Skovgaard; Michael Larsen
TAGS: drusen, child, cohort studies, retinal drusen, eye
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1454-1460. doi: 10.1167/iovs.18-25877

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Effect of Anesthesia on Intraocular Pressure Measured With Continuous Wireless Telemetry in Nonhuman Primates

Ocular Axial Length and Diabetic Retinopathy: The Kailuan Eye Study

Visual Function and Functional Decline in Patients With Waterclefts

Diabetic Optic Neuropathy and Its Risk Factors in Chinese Patients With Diabetic Retinopathy

Increased Nonexudative Age-Related Macular Degeneration Diagnosis Among Medicare Beneficiaries With Rheumatoid Arthritis

Role of Parental Refractive Status in Myopia Progression: 12-Year Annual Observation From the Guangzhou Twin Eye Study

Longitudinal Changes in Spherical Equivalent of Moderate to High Hyperopia: 2- to 8-Year Follow-Up of Children at an Initial Age of 5.5 to 8.4 Years

Impact of the Morphologic Characteristics of Optic Disc on Choroidal Thickness in Young Myopic Patients

Placental CpG Methylation of Inflammation, Angiogenic, and Neurotrophic Genes and Retinopathy of Prematurity

Trends in the Prevalence of Myopia and Myopic Maculopathy in a Japanese Population: The Hisayama Study

Overt Proteinuria, Moderately Reduced eGFR and Their Combination Are Predictive of Severe Diabetic Retinopathy or Diabetic Macular Edema in Diabetes

Size and Shape of Bruch's Membrane Opening in Relationship to Axial Length, Gamma Zone, and Macular Bruch's Membrane Defects

Subfoveal Choroidal Thickness, Cardiovascular History, and Risk Factors in the Elderly: The Montrachet Study

Human Meibum Cholesteryl and Wax Ester Variability With Age, Sex, and Meibomian Gland Dysfunction

Factors Associated With Retinal Vessel Diameters in an Elderly Population: the Thessaloniki Eye Study

Vitreomacular Interface Abnormalities and Glaucoma in an Elderly Population (The MONTRACHET Study)

InflammAging at Ocular Surface: Clinical and Biomolecular Analyses in Healthy Volunteers

Retinal Layer Thicknesses in Early Age-Related Macular Degeneration: Results From the German AugUR Study

The Common Antidiabetic Drug Metformin Reduces Odds of Developing Age-Related Macular Degeneration

Small Hard Macular Drusen and Associations in 11- to 12-Year-Old Children in the Copenhagen Child Cohort 2000 Eye Study

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