Cornea

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Cornea October 2019

Hyperglycemia Suppresses Age-Related Increases in Corneal Peripheral Sensory Nerves in Wistar Bon Kobori (WBN/Kob) Rats

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Kiyokazu Ozaki; Yui Terayama; Tetsuro Matsuura
TAGS: cornea, hyperglycemia, neurons, rats, sensory nerves, diabetes mellitus
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4151-4158. doi: 10.1167/iovs.19-28060

Glaucoma October 2019

Association of Corneal Hysteresis With Lamina Cribrosa Curvature in Primary Open Angle Glaucoma

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Kyoung Min Lee; Tae-Woo Kim; Eun Ji Lee; Michaël J. A. Girard; Jean Martial Mari; Robert N. Weinreb
TAGS: cornea, corneal hysteresis, cribriform plate, genu varum, open-angle glaucoma, eye, glaucoma, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4171-4177. doi: 10.1167/iovs.19-27087

Includes: Supplemental Content

Cornea October 2019

Influence of Vitamin D on Corneal Epithelial Cell Desmosomes and Hemidesmosomes

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Xiaowen Lu; Mitchell A. Watsky
TAGS: corneal epithelial cells, corneal epithelium, desmosomes, hemidesmosomes, integrins, mice, proteins, vitamin d, cornea
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4074-4083. doi: 10.1167/iovs.19-27796

Includes: Supplemental Content

Physiology and Pharmacology September 2019

In Vivo Fluorescence Visualization of Anterior Chamber Injected Human Corneal Endothelial Cells Labeled With Quantum Dots

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Munetoyo Toda; Hiroshi Yukawa; Jun Yamada; Morio Ueno; Shigeru Kinoshita; Yoshinobu Baba; Junji Hamuro
TAGS: anterior chamber of eye, cornea, endothelial cells, eye, fluorescence, mice, quantum dots, diagnostic imaging, injections
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):4008-4020. doi: 10.1167/iovs.19-27788

Includes: Supplemental Content

Immunology and Microbiology September 2019

CCR6-Positive γδ T Cells Provide Protection Against Intracorneal HSV-1 Infection

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Steffani Fitzpatrick; Robert Lausch; Robert A. Barrington
TAGS: cornea, human herpesvirus 1, infection, t-lymphocytes, mice, interleukin-17
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3952-3962. doi: 10.1167/iovs.19-27810

Cornea September 2019

Quantitative Studies of Muscleblind Proteins and Their Interaction With TCF4 RNA Foci Support Involvement in the Mechanism of Fuchs' Dystrophy

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Ziye Rong; Jiaxin Hu; David R. Corey; V. Vinod Mootha
TAGS: proteins, rna, cornea, body tissue
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3980-3991. doi: 10.1167/iovs.19-27641

Includes: Supplemental Content

Cornea September 2019

The Role of the miR-21/SPRY2 Axis in Modulating Proangiogenic Factors, Epithelial Phenotypes, and Wound Healing in Corneal Epithelial Cells

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Yun Zhang; Fukang Yuan; Lin Liu; Zufeng Chen; Xiaoyun Ma; Zhen Lin; Jun Zou
TAGS: corneal epithelial cells, epithelium, phenotype, wound healing, hypoxia
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3854-3862. doi: 10.1167/iovs.19-27013

Cornea September 2019

Relations Among Corneal Curvature, Thickness, and Volume in Keratoconus as Evaluated by Anterior Segment–Optical Coherence Tomography

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Naoyuki Morishige; Kazuyoshi Magome; Akifumi Ueno; Taka-Aki Matsui; Teruo Nishida
TAGS: cicatrix, cornea, keratoconus, optical coherence tomography, volume, eye
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3794-3802. doi: 10.1167/iovs.19-27619

Includes: Supplemental Content

Cornea September 2019

Therapeutic Effects of STAT3 Inhibition on Experimental Murine Dry Eye

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Mingli Qu; Xia Qi; Qian Wang; Lei Wan; Jing Li; Wei Li; Yingli Li; Qingjun Zhou
TAGS: dry eye syndromes, mice, stat3 protein
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3776-3785. doi: 10.1167/iovs.19-26928

Cornea September 2019

The Effect of Chloroquine on the Development of Dry Eye in Sjögren Syndrome Animal Model

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Hyun Jung Lee; Soojung Shin; Seul-Gi Yoon; Eun Jeong Cheon; So-Hyang Chung
TAGS: animal model, chloroquine, dry eye syndromes, mice, sjogren's syndrome, syndrome, autophagy, sjogren's syndrome a antibody, phenotype, cornea
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3708-3716. doi: 10.1167/iovs.19-27469

Includes: Supplemental Content

Cornea September 2019

Effects of Amniotic Membrane–Derived Fibroblast Supernatant on Corneal Epithelium

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Kazunari Higa; Junko Higuchi; Reona Kimoto; Yoshiyuki Satake; Takefumi Yamaguchi; Daisuke Tomida; Jun Shimazaki
TAGS: amnion, cornea, corneal epithelium, epithelium, fibroblasts, wound healing, oryctolagus cuniculus, antibodies, flow cytometry
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3718-3726. doi: 10.1167/iovs.19-27041

Cornea August 2019

Induction of Fibroblast Senescence During Mouse Corneal Wound Healing

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Xiaolei Wang; Mingli Qu; Jing Li; Patrik Danielson; Lingling Yang; Qingjun Zhou
TAGS: aging, cornea, fibroblasts, mice, wound healing, myofibroblasts
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3669-3679. doi: 10.1167/iovs.19-26983

Includes: Supplemental Content

Cornea August 2019

Gene Expression and Missplicing in the Corneal Endothelium of Patients With a TCF4 Trinucleotide Repeat Expansion Without Fuchs' Endothelial Corneal Dystrophy

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Eric D. Wieben; Keith H. Baratz; Ross A. Aleff; Krishna R. Kalari; Xiaojia Tang; Leo J. Maguire; Sanjay V. Patel; Michael P. Fautsch
TAGS: corneal endothelium, endothelium, gene expression, genes, hereditary corneal dystrophy, trinucleotide repeat expansion, rna splicing, dna, rna
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3636-3643. doi: 10.1167/iovs.19-27689

Includes: Supplemental Content

Cornea August 2019

Single-Cell RNA Transcriptome Helps Define the Limbal/Corneal Epithelial Stem/Early Transit Amplifying Cells and How Autophagy Affects This Population

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Nihal Kaplan; Junyi Wang; Brian Wray; Priyam Patel; Wending Yang; Han Peng; Robert M. Lavker
TAGS: cornea, epithelium, mice, rna, small cytoplasmic, autophagy, genes, rna, beclin-1
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3570-3583. doi: 10.1167/iovs.19-27656

Includes: Supplemental Content

Cornea August 2019

Corneal Denervation Causes Epithelial Apoptosis Through Inhibiting NAD + Biosynthesis

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Ya Li; Xiubin Ma; Jing Li; Lingling Yang; Xiaowen Zhao; Xia Qi; Xiaoping Zhang; Qingjun Zhou; Weiyun Shi
TAGS: apoptosis, biosynthesis, cornea, denervation, epithelium, corneal epithelium
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3538-3546. doi: 10.1167/iovs.19-26909

Includes: Supplemental Content

Cornea August 2019

Small Molecule Modulation of the Integrated Stress Response Governs the Keratoconic Phenotype In Vitro

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Uri Simcha Soiberman; Ahmed Elsayed Mahmoud Shehata; Michelle Xiaoyi Lu; Tempest Young; Yassine J. Daoud; Shukti Chakravarti; Albert S. Jun; James William Foster
TAGS: keratoconus, phenotype, regulation, small molecule, stress response, fibroblasts, proteins, cell count, collagen synthesis, cornea
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3422-3431. doi: 10.1167/iovs.19-27151

Includes: Supplemental Content

Immunology and Microbiology August 2019

Loss of ICP22 in HSV-1 Elicits Immune Infiltration and Maintains Stromal Keratitis Despite Reduced Primary and Latent Virus Infectivity

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Harry H. Matundan; Ujjaldeep Jaggi; Shaohui Wang; Homayon Ghiasi
TAGS: eye, human herpesvirus 1, mice, viruses, keratitis, stromal, pathogenicity, cornea, cd80 antigens, infection
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3398-3406. doi: 10.1167/iovs.19-27701

Cornea August 2019

Evaluation of Corneal Damage After Lacrimal Gland Excision in Male and Female Mice

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Neal E. Mecum; Dan Cyr; Jennifer Malon; Danielle Demers; Ling Cao; Ian D. Meng
TAGS: corneal injuries, excision, lacrimal gland, linear gingival erythema, mice, cornea, fluorescein, surgical procedures, operative, mice, inbred c57bl, dry eye syndromes
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3264-3274. doi: 10.1167/iovs.18-26457

Cornea July 2019

Corneal Properties of Keratoconus Based on Scheimpflug Light Intensity Distribution

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Alejandra Consejo; Karolina Gławdecka; Karol Karnowski; Jędrzej Solarski; Jos J. Rozema; Maciej Wojtkowski; D. Robert Iskander
TAGS: cornea, keratoconus, light intensity
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3197-3203. doi: 10.1167/iovs.19-26963

Cornea July 2019

Modulation of Contact Inhibition by ZO-1/ZONAB Gene Transfer—A New Strategy to Increase the Endothelial Cell Density of Corneal Grafts

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Daniel Kampik; Mark Basche; Anastasios Georgiadis; Ulrich F. O. Luhmann; D. Frank Larkin; Alexander J. Smith; Robin R. Ali
TAGS: contact inhibition, cornea, endothelial cells, endothelium, keratoplasty, gene therapy, gene transfer techniques
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3170-3177. doi: 10.1167/iovs.18-26260

Includes: Supplemental Content

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Hyperglycemia Suppresses Age-Related Increases in Corneal Peripheral Sensory Nerves in Wistar Bon Kobori (WBN/Kob) Rats

Association of Corneal Hysteresis With Lamina Cribrosa Curvature in Primary Open Angle Glaucoma

Influence of Vitamin D on Corneal Epithelial Cell Desmosomes and Hemidesmosomes

In Vivo Fluorescence Visualization of Anterior Chamber Injected Human Corneal Endothelial Cells Labeled With Quantum Dots

CCR6-Positive γδ T Cells Provide Protection Against Intracorneal HSV-1 Infection

Quantitative Studies of Muscleblind Proteins and Their Interaction With TCF4 RNA Foci Support Involvement in the Mechanism of Fuchs' Dystrophy

The Role of the miR-21/SPRY2 Axis in Modulating Proangiogenic Factors, Epithelial Phenotypes, and Wound Healing in Corneal Epithelial Cells

Relations Among Corneal Curvature, Thickness, and Volume in Keratoconus as Evaluated by Anterior Segment–Optical Coherence Tomography

Therapeutic Effects of STAT3 Inhibition on Experimental Murine Dry Eye

The Effect of Chloroquine on the Development of Dry Eye in Sjögren Syndrome Animal Model

Effects of Amniotic Membrane–Derived Fibroblast Supernatant on Corneal Epithelium

Induction of Fibroblast Senescence During Mouse Corneal Wound Healing

Gene Expression and Missplicing in the Corneal Endothelium of Patients With a TCF4 Trinucleotide Repeat Expansion Without Fuchs' Endothelial Corneal Dystrophy

Single-Cell RNA Transcriptome Helps Define the Limbal/Corneal Epithelial Stem/Early Transit Amplifying Cells and How Autophagy Affects This Population

Corneal Denervation Causes Epithelial Apoptosis Through Inhibiting NAD + Biosynthesis

Small Molecule Modulation of the Integrated Stress Response Governs the Keratoconic Phenotype In Vitro

Loss of ICP22 in HSV-1 Elicits Immune Infiltration and Maintains Stromal Keratitis Despite Reduced Primary and Latent Virus Infectivity

Evaluation of Corneal Damage After Lacrimal Gland Excision in Male and Female Mice

Corneal Properties of Keratoconus Based on Scheimpflug Light Intensity Distribution

Modulation of Contact Inhibition by ZO-1/ZONAB Gene Transfer—A New Strategy to Increase the Endothelial Cell Density of Corneal Grafts

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