Cornea

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Cornea September 2022

METTL3 Attenuates Inflammation in Fusarium solani –Induced Keratitis via the PI3K/AKT Signaling Pathway

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Liwei Huang; Hanfeng Tang; Jianzhang Hu
TAGS: 1-phosphatidylinositol 3-kinase, akt signaling pathway, cornea, inflammation, keratitis, mice, signal pathway, signal transduction pathways, fusarium solani, infections
Invest. Ophthalmol. Vis. Sci.. 2022; 63(10):20. doi: https://doi.org/10.1167/iovs.63.10.20

Cornea September 2022

SIRT1 Protects Against Particulate Matter-Induced Oxidative Stress in Human Corneal and Conjunctival Epithelial Cells

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Xiangzhe Li; Boram Kang; Youngsub Eom; Jingxiang Zhong; Hyung Keun Lee; Hyo Myung Kim; Jong Suk Song
TAGS: apoptosis, cellular senescence, conjunctival epithelial cells, cornea, cytotoxicity, oxidative stress, prevention, transcriptional activation, ocular surfaces, proteins
Invest. Ophthalmol. Vis. Sci.. 2022; 63(10):19. doi: https://doi.org/10.1167/iovs.63.10.19

Includes: Supplemental Content

Cornea September 2022

AKR1C1 Protects Corneal Epithelial Cells Against Oxidative Stress-Mediated Ferroptosis in Dry Eye

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Xin Zuo; Hao Zeng; Bowen Wang; Xue Yang; Dalian He; Li Wang; Hong Ouyang; Jin Yuan
TAGS: corneal epithelial cells, dry eye syndromes, ferroptosis, stress
Invest. Ophthalmol. Vis. Sci.. 2022; 63(10):3. doi: https://doi.org/10.1167/iovs.63.10.3

Includes: Supplemental Content

Retina August 2022

Quantification and Predictors of OCT-Based Macular Curvature and Dome-Shaped Configuration: Results From the UK Biobank

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Philipp L. Müller; Yuka Kihara; Abraham Olvera-Barrios; Alasdair N. Warwick; Catherine Egan; Katie M. Williams; Aaron Y. Lee; Adnan Tufail; for the UK Biobank Eyes and Vision Consortium
TAGS: biobanks, cohort studies, eye, myopia, refractive errors, diagnostic imaging, ethnic group, hyperopia, smoking in pregnancy, congenital abnormality
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):28. doi: https://doi.org/10.1167/iovs.63.9.28

Includes: Supplemental Content

Clinical and Epidemiologic Research July 2022

Foveal Curvature and Its Associations in UK Biobank Participants

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Abraham Olvera-Barrios; Yuka Kihara; Yue Wu; Alasdair N. Warwick; Philipp L. Müller; Katie M. Williams; Alicja R. Rudnicka; Christopher G. Owen; Aaron Y. Lee; Catherine Egan; Adnan Tufail; on behalf of the UK Biobank Eyes and Vision Consortium
TAGS: biobanks, ethnic group, income, eye, astigmatism, fovea centralis
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):26. doi: https://doi.org/10.1167/iovs.63.8.26

Includes: Supplemental Content

Cornea July 2022

Labial Mucosa Stem Cells: Isolation, Characterization, and Their Potential for Corneal Epithelial Reconstruction

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Kirill E. Zhurenkov; Elga I. Alexander-Sinkler; Ilya O. Gavrilyik; Natalia M. Yartseva; Svetlana A. Aleksandrova; Tatiana V. Mashel; Julia I. Khorolskaya; Miralda I. Blinova; Alexei N. Kulikov; Sergei V. Churashov; Valery F. Chernysh; Natalia A. Mikhailova
TAGS: cornea, epithelium, lip, mucous membrane, oryctolagus cuniculus, patient isolation, reconstructive surgical procedures, social isolation, stem cells, tissue transplants
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):16. doi: https://doi.org/10.1167/iovs.63.8.16

Includes: Supplemental Content

Cornea July 2022

The NLRP3 Activation in Infiltrating Macrophages Contributes to Corneal Fibrosis by Inducing TGF-β1 Expression in the Corneal Epithelium

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Jing Xu; Peng Chen; Xiaoyu Luan; Xinying Yuan; Susu Wei; Yaxin Li; Chuanlong Guo; Xianggen Wu; Guohu Di
TAGS: cicatrix, cornea, fibrosis, macrophages, nlr family, pyrin domain-containing 3 protein, corneal epithelium
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):15. doi: https://doi.org/10.1167/iovs.63.8.15

Includes: Supplemental Content

Cornea July 2022

Altered Regulation of mRNA and miRNA Expression in Epithelial and Stromal Tissue of Keratoconus Corneas

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Tanja Stachon; Mahsa Nastaranpour; Berthold Seitz; Eckart Meese; Lorenz Latta; Suphi Taneri; Navid Ardjomand; Nóra Szentmáry; Nicole Ludwig
TAGS: cornea, epithelium, micrornas, rna, messenger, keratoconus, body tissue, regulation
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):7. doi: https://doi.org/10.1167/iovs.63.8.7

Includes: Supplemental Content

Cornea July 2022

Integrated Stress Response Regulation of Corneal Epithelial Cell Motility and Cytokine Production

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Hsiao-Sang Chu; Cornelia Peterson; Xitiz Chamling; Cynthia Berlinicke; Donald Zack; Albert S. Jun; James Foster
TAGS: agonists, cell lines, cell motility, corneal epithelial cells, corneal epithelium, cyclophosphamide, doxorubicin, prednisone, and vincristine, cytokine, regulation, stress response, cornea
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):1. doi: https://doi.org/10.1167/iovs.63.8.1

Includes: Supplemental Content

Biochemistry and Molecular Biology June 2022

Early Dry Eye Disease Onset in a NOD.H-2 h4 Mouse Model of Sjögren's Syndrome

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Lili Li; Kimberly J. Jasmer; Jean M. Camden; Lucas T. Woods; Adam L. Martin; Yong Yang; Maria Layton; Michael J. Petris; Olga J. Baker; Gary A. Weisman; Carisa K. Petris
TAGS: mice, dry eye syndromes, sjogren's syndrome
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):18. doi: https://doi.org/10.1167/iovs.63.6.18

Includes: Supplemental Content

Cornea June 2022

Lysozyme Protects Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Inflammation in Human Corneal Epithelial Cells

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Yinting Song; Haokun Zhang; Yanfang Zhu; Xiao Zhao; Yi Lei; Wei Zhou; Jinguo Yu; Xue Dong; Xiaohong Wang; Mei Du; Hua Yan
TAGS: covid-19, infections, inflammation, muramidase, proteins, severe acute respiratory syndrome, corneal epithelial cells, sars-cov-2, coronavirus
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):16. doi: https://doi.org/10.1167/iovs.63.6.16

Cornea June 2022

Corneal Epithelium–Derived Netrin-1 Alleviates Dry Eye Disease via Regulating Dendritic Cell Activation

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Chaoqun Yu; Peng Chen; Jing Xu; Susu Wei; Qilong Cao; Chuanlong Guo; Xianggen Wu; Guohu Di
TAGS: cornea, corneal epithelium, dendritic cells, dry eye syndromes, mice, netrin-1, regulation, antibodies
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):1. doi: https://doi.org/10.1167/iovs.63.6.1

Anatomy and Pathology/Oncology May 2022

Scleral Cross-Linking in Form-Deprivation Myopic Guinea Pig Eyes Leads to Glaucomatous Changes

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Lei Guo; Rui Hua; Xinxin Zhang; Ting Yu Yan; Yang Tong; Xin Zhao; Shi Chao Chen; Moying Wang; Neil M. Bressler; Jun Kong
TAGS: corneal collagen cross-linking, cross-linking, eye, glaucoma, guinea, sclera, myopia
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):24. doi: https://doi.org/10.1167/iovs.63.5.24

Cornea May 2022

Comprehensive Analysis Identified the Circadian Clock and Global Circadian Gene Expression in Human Corneal Endothelial Cells

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Hiroko Nakai; Yoshiki Tsuchiya; Nobuya Koike; Taiki Asano; Morio Ueno; Yasuhiro Umemura; Yuh Sasawaki; Ryutaro Ono; Junji Hamuro; Chie Sotozono; Kazuhiro Yagita
TAGS: circadian clocks, cornea, endothelial cells, gene expression, chronic exertional compartment syndrome, genes, rhythm, bioluminescence
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):16. doi: https://doi.org/10.1167/iovs.63.5.16

Includes: Multimedia, Supplemental Content

Cornea May 2022

Shotgun Proteomics for the Identification and Profiling of the Tear Proteome of Keratoconus Patients

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Maite López-López; Uxía Regueiro; Susana Belén Bravo; María del Pilar Chantada-Vázquez; Carmen Pena; Elío Díez-Feijoo; Pablo Hervella; Isabel Lema
TAGS: keratoconus, proteins, proteome, proteomics, enzyme-linked immunosorbent assay
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):12. doi: https://doi.org/10.1167/iovs.63.5.12

Includes: Supplemental Content

Cornea May 2022

Melatonin Attenuates LPS-Induced Proinflammatory Cytokine Response and Lipogenesis in Human Meibomian Gland Epithelial Cells via MAPK/NF-κB Pathway

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Ren Liu; Jing Li; Yue Xu; Ziyan Chen; Huijing Ye; Jinhui Tang; Lai Wei; Lingyi Liang
TAGS: cytokine, epithelial cells, lipogenesis, meibomian gland, melatonin, mitogen-activated protein kinases, proteins, toll-like receptor 4
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):6. doi: https://doi.org/10.1167/iovs.63.5.6

Includes: Supplemental Content

Cornea May 2022

Limbal Niche Cells and Three-Dimensional Matrigel-Induced Dedifferentiation of Mature Corneal Epithelial Cells

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Hui Zhu; Wei Wang; Yongyao Tan; Guanyu Su; Lingjuan Xu; Meng lin Jiang; Shen Li; Yaa-Jyuhn James Meir; Yunming Wang; Guigang Li; Huamin Zhou
TAGS: anaplasia, corneal epithelial cells, epithelial cells, epithelium, cornea, stem cells
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):1. doi: https://doi.org/10.1167/iovs.63.5.1

Includes: Supplemental Content

Cornea April 2022

Repressed miR-34a Expression Dictates the Cell Fate to Corneal Endothelium Failure

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Junji Hamuro; Kazuko Asada; Morio Ueno; Tomoko Yamashita; Atsushi Mukai; Tomoko Fujita; Eiko Ito; Nao Hiramoto; Munetoyo Toda; Chie Sotozono; Shigeru Kinoshita
TAGS: cd44 antigens, cells, corneal endothelium, gelatinase a, homing-associated cell adhesion molecule, micrornas, mitochondria, patient simulation, prostate health index, protected health information
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):22. doi: https://doi.org/10.1167/iovs.63.4.22

Includes: Supplemental Content

Cornea April 2022

Analysis of MicroRNA Expression in Tears of Patients with Herpes Epithelial Keratitis: A Preliminary Study

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Yu Jeong Kim; Yeji Yeon; Won June Lee; Yong Un Shin; Heeyoon Cho; Han Woong Lim; Min Ho Kang
TAGS: micrornas, epithelial keratitis, simplexvirus, ulcer
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):21. doi: https://doi.org/10.1167/iovs.63.4.21

Cornea April 2022

Forkhead Domain Inhibitor-6 Suppresses Corneal Neovascularization and Subsequent Fibrosis After Alkali Burn in Rats

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Chunlin Lan; Guo Liu; Longxiang Huang; Xizhen Wang; Junkai Tan; Yun Wang; Ning Fan; Yihua Zhu; Man Yu; Xuyang Liu
TAGS: alkalies, burns, cornea, corneal neovascularization, fibrosis, inflammation, rats
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):14. doi: https://doi.org/10.1167/iovs.63.4.14

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METTL3 Attenuates Inflammation in Fusarium solani –Induced Keratitis via the PI3K/AKT Signaling Pathway

SIRT1 Protects Against Particulate Matter-Induced Oxidative Stress in Human Corneal and Conjunctival Epithelial Cells

AKR1C1 Protects Corneal Epithelial Cells Against Oxidative Stress-Mediated Ferroptosis in Dry Eye

Quantification and Predictors of OCT-Based Macular Curvature and Dome-Shaped Configuration: Results From the UK Biobank

Foveal Curvature and Its Associations in UK Biobank Participants

Labial Mucosa Stem Cells: Isolation, Characterization, and Their Potential for Corneal Epithelial Reconstruction

The NLRP3 Activation in Infiltrating Macrophages Contributes to Corneal Fibrosis by Inducing TGF-β1 Expression in the Corneal Epithelium

Altered Regulation of mRNA and miRNA Expression in Epithelial and Stromal Tissue of Keratoconus Corneas

Integrated Stress Response Regulation of Corneal Epithelial Cell Motility and Cytokine Production

Early Dry Eye Disease Onset in a NOD.H-2 h4 Mouse Model of Sjögren's Syndrome

Lysozyme Protects Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Inflammation in Human Corneal Epithelial Cells

Corneal Epithelium–Derived Netrin-1 Alleviates Dry Eye Disease via Regulating Dendritic Cell Activation

Scleral Cross-Linking in Form-Deprivation Myopic Guinea Pig Eyes Leads to Glaucomatous Changes

Comprehensive Analysis Identified the Circadian Clock and Global Circadian Gene Expression in Human Corneal Endothelial Cells

Shotgun Proteomics for the Identification and Profiling of the Tear Proteome of Keratoconus Patients

Melatonin Attenuates LPS-Induced Proinflammatory Cytokine Response and Lipogenesis in Human Meibomian Gland Epithelial Cells via MAPK/NF-κB Pathway

Limbal Niche Cells and Three-Dimensional Matrigel-Induced Dedifferentiation of Mature Corneal Epithelial Cells

Repressed miR-34a Expression Dictates the Cell Fate to Corneal Endothelium Failure

Analysis of MicroRNA Expression in Tears of Patients with Herpes Epithelial Keratitis: A Preliminary Study

Forkhead Domain Inhibitor-6 Suppresses Corneal Neovascularization and Subsequent Fibrosis After Alkali Burn in Rats

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