Eye Anatomy and Disorders

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Cornea November 2018

Sleep Deprivation Induces Dry Eye Through Inhibition of PPARα Expression in Corneal Epithelium

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Liying Tang; Xue Wang; Jieli Wu; San Ming Li; Zhaoqiang Zhang; Sangang Wu; Ting Su; Zhirong Lin; Xueting Chen; Xulin Liao; Ting Bai; Yan Qiu; Peter Sol Reinach; Wei Li; Yongxiong Chen; Zuguo Liu
TAGS: dry eye syndromes, corneal epithelium, microvilli, sleep deprivation, cornea, lipids, mice, sleep, morphology, ppar alpha, language morphology
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5494-5508. doi: 10.1167/iovs.18-24504

Cornea November 2018

Assessment of Topical Therapies for Improving the Optical Clarity Following Stromal Wounding in a Novel Ex Vivo Canine Cornea Model

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William M. Berkowski; Daniel J. Gibson; SooJung Seo; Laura R. Proietto; R. David Whitley; Gregory S. Schultz; Caryn E. Plummer
TAGS: fibrosis, optics, placebos, sepharose, wounds and injuries, cornea, epithelialization, vorinostat, pirfenidone, dog, domestic, corneal opacity
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5509-5521. doi: 10.1167/iovs.17-23085

Article November 2018

An object-tracking model that combines position and speed explains spatial and temporal responses in a timing task

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David Aguilar-Lleyda; Elisabet Tubau; Joan López-Moliner
TAGS: motion, reaction time, noise, reward, filters
Journal of Vision. 2018; 18(12):12. doi: 10.1167/18.12.12

Article November 2018

Natural visual behavior in individuals with peripheral visual-field loss

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Ricardo Ramos Gameiro; Kristin Jünemann; Anne Herbik; Anika Wolff; Peter König; Michael B. Hoffmann
TAGS: saccades, visual fields
Journal of Vision. 2018; 18(12):10. doi: 10.1167/18.12.10

Article November 2018

Investigating overt and covert shifts of attention within social naturalistic scenes

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Aleya Flechsenhar; Olivia Larson; Albert End; Matthias Gamer
TAGS: attention
Journal of Vision. 2018; 18(12):11. doi: 10.1167/18.12.11

Visual Psychophysics and Physiological Optics November 2018

Orientation Tuning and Contrast Dependence of Continuous Flash Suppression in Amblyopia and Normal Vision

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Tina Y. Gao; Timothy Ledgeway; Alyssa L. Lie; Nicola Anstice; Joanna Black; Paul V. McGraw; Benjamin Thompson
TAGS: amblyopia, eye, noise, emmetropia
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5462-5472. doi: 10.1167/iovs.18-23954

Includes: Supplemental Content

Glaucoma November 2018

Mesenchymal Stem Cell–Derived Small Extracellular Vesicles Promote Neuroprotection in a Genetic DBA/2J Mouse Model of Glaucoma

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Ben Mead; Zubair Ahmed; Stanislav Tomarev
TAGS: glaucoma, ocular hypertension, genetics, mice, stem cell, mesenchymal, neuroprotection, exosomes, extracellular vesicles
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5473-5480. doi: 10.1167/iovs.18-25310

Includes: Supplemental Content

Retina November 2018

Disorganization of Retinal Inner Layers (DRIL) and Neuroretinal Dysfunction in Early Diabetic Retinopathy

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Katherine A. Joltikov; Christopher A. Sesi; Vinícius M. de Castro; José R. Davila; Rohit Anand; Sami M. Khan; Neil Farbman; Gregory R. Jackson; Chris A. Johnson; Thomas W. Gardner
TAGS: diabetes mellitus, diabetic retinopathy, contrast sensitivity, perimetry, visual acuity, fundus photography, pathophysiology, shedler-westen assessment procedure–200, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5481-5486. doi: 10.1167/iovs.18-24955

Visual Psychophysics and Physiological Optics November 2018

Macular Inner Retinal Layer Thickness in Relation to Photopic and Mesopic Contrast Sensitivity in Healthy Young and Older Subjects

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María Cinta Puell; Catalina Palomo-Álvarez; María Jesús Pérez-Carrasco
TAGS: glaucoma, contrast sensitivity, eye, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5487-5493. doi: 10.1167/iovs.18-25334

Methods November 2018

Curveball: A tool for rapid measurement of contrast sensitivity based on smooth eye movements

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Scott W. J. Mooney; N. Jeremy Hill; Melis S. Tuzun; Nazia M. Alam; Jason B. Carmel; Glen T. Prusky
TAGS: eye movement, colony-stimulating factors, contrast sensitivity, noise, stairs, spatial frequency
Journal of Vision. 2018; 18(12):7. doi: 10.1167/18.12.7

Includes: Multimedia, Supplemental Content

Visual Psychophysics and Physiological Optics November 2018

Estimation of Contrast Sensitivity From Fixational Eye Movements

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Jonathan Denniss; Chris Scholes; Paul V. McGraw; Se-Ho Nam; Neil W. Roach
TAGS: eye movement, contrast sensitivity
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5408-5416. doi: 10.1167/iovs.18-24674

Retina November 2018

Clinically Relevant Outcome Measures for the I307N Rhodopsin Mouse: A Model of Inducible Autosomal Dominant Retinitis Pigmentosa

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Michael T. Massengill; Brianna Young; Deep Patel; Farwa Jafri; Ernesto Sabogal; Neil Ash; Hong Li; Cristhian J. Ildefonso; Alfred S. Lewin
TAGS: photoreceptors, retinal degeneration, retinitis pigmentosa, mice, retina, outcome measures, spectral-domain optical coherence tomography, rhodopsin
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5417-5430. doi: 10.1167/iovs.18-25345

Includes: Supplemental Content

Biochemistry and Molecular Biology November 2018

SIRT1 Deletion Impairs Retinal Endothelial Cell Migration Through Downregulation of VEGF-A/VEGFR-2 and MMP14

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Yong Lin; Li Li; Junjie Liu; Xiaoting Zhao; Juxiu Ye; Peter S. Reinach; Jia Qu; Dongsheng Yan
TAGS: angiogenesis, vascular endothelial growth factor a, western blotting, endothelial cells, vascular endothelial growth factor receptor-2, down-regulation, mice, rna, small interfering
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5431-5440. doi: 10.1167/iovs.17-23558

Includes: Supplemental Content

Anatomy and Pathology/Oncology November 2018

Blood Flow in Monocular Retinoblastoma Assessed by Color Doppler and Correlations With High-Risk Pathologic Features

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Maria Teresa B. C. Bonanomi; Osmar C. Saito; Patricia Picciarelli de Lima; Roberta Chizzotti Bonanomi; Maria Cristina Chammas
TAGS: doppler color flow, vascular flow, doppler echocardiography, retinoblastoma, eye, neoplasms, optic nerve, particle image velocimetry
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5441-5446. doi: 10.1167/iovs.18-24777

Glaucoma November 2018

The Relationship Between the Sighting Eye and Functional and Structural Asymmetries in Glaucoma

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Jin A Choi; Il-Young Jung; Donghyun Jee
TAGS: glaucoma, eye
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5447-5454. doi: 10.1167/iovs.18-24083

Includes: Supplemental Content

Articles November 2018

Prevalence and Determinants Associated With Spectacle-Wear Compliance in Aphakic Infants

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Qianzhong Cao; Xiaoyan Li; Duoru Lin; Zhenzhen Liu; Jing Li; Haofeng Jiang; Zhuoling Lin; Jingjing Chen; Xiaohang Wu; Erping Long; Yingfen Lin; Jinzhu Tang; Xing Chen; Sijian Huang; Haotian Lin; Weirong Chen; Yizhi Liu
TAGS: caregivers, eyeglasses, infant, prevalence
Trans. Vis. Sci. Tech.. 2018; 7(6):5. doi: 10.1167/tvst.7.6.5

Includes: Supplemental Content

Articles November 2018

Rho-Kinase Inhibition Reduces Myofibroblast Differentiation and Proliferation of Scleral Fibroblasts Induced by Transforming Growth Factor β and Experimental Glaucoma

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Ian Pitha; Ericka Oglesby; Amanda Chow; Elizabeth Kimball; Mary Ellen Pease; Julie Schaub; Harry Quigley
TAGS: fibroblasts, glaucoma, collagen, patient isolation, phosphotransferases, transforming growth factors, eye, intraocular pressure, sclera, myofibroblasts
Trans. Vis. Sci. Tech.. 2018; 7(6):6. doi: 10.1167/tvst.7.6.6

Includes: Supplemental Content

Articles November 2018

Noninvasive Assessment of Retinal Blood Flow Using a Novel Handheld Laser Speckle Contrast Imager

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Abhishek Rege; Samantha I. Cunningham; Yusi Liu; Karan Raje; Sachin Kalarn; M. Jason Brooke; Lisa Schocket; Sunni Scott; Asifa Shafi; Luis Toledo; Osamah J. Saeedi
TAGS: vascular flow, lasers, diagnostic imaging, fundus photography, mobile devices
Trans. Vis. Sci. Tech.. 2018; 7(6):7. doi: 10.1167/tvst.7.6.7

Letters to the Editor November 2018

Hyperreflective Intraretinal Foci as an OCT Biomarker of Retinal Inflammation in Diabetic Macular Edema

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Edoardo Midena; Elisabetta Pilotto; Silvia Bini
TAGS: biological markers, retinitis, macular edema, diabetic
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5366-5366. doi: 10.1167/iovs.18-25611

Letters to the Editor November 2018

Author Response: Hyperreflective Intraretinal Foci as an OCT Biomarker of Retinal Inflammation in Diabetic Macular Edema

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Hyungwoo Lee; Hyewon Chung
TAGS: biological markers, retinitis, macular edema, diabetic
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5367-5367. doi: 10.1167/iovs.18-25825

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Sleep Deprivation Induces Dry Eye Through Inhibition of PPARα Expression in Corneal Epithelium

Assessment of Topical Therapies for Improving the Optical Clarity Following Stromal Wounding in a Novel Ex Vivo Canine Cornea Model

An object-tracking model that combines position and speed explains spatial and temporal responses in a timing task

Natural visual behavior in individuals with peripheral visual-field loss

Investigating overt and covert shifts of attention within social naturalistic scenes

Orientation Tuning and Contrast Dependence of Continuous Flash Suppression in Amblyopia and Normal Vision

Mesenchymal Stem Cell–Derived Small Extracellular Vesicles Promote Neuroprotection in a Genetic DBA/2J Mouse Model of Glaucoma

Disorganization of Retinal Inner Layers (DRIL) and Neuroretinal Dysfunction in Early Diabetic Retinopathy

Macular Inner Retinal Layer Thickness in Relation to Photopic and Mesopic Contrast Sensitivity in Healthy Young and Older Subjects

Curveball: A tool for rapid measurement of contrast sensitivity based on smooth eye movements

Estimation of Contrast Sensitivity From Fixational Eye Movements

Clinically Relevant Outcome Measures for the I307N Rhodopsin Mouse: A Model of Inducible Autosomal Dominant Retinitis Pigmentosa

SIRT1 Deletion Impairs Retinal Endothelial Cell Migration Through Downregulation of VEGF-A/VEGFR-2 and MMP14

Blood Flow in Monocular Retinoblastoma Assessed by Color Doppler and Correlations With High-Risk Pathologic Features

The Relationship Between the Sighting Eye and Functional and Structural Asymmetries in Glaucoma

Prevalence and Determinants Associated With Spectacle-Wear Compliance in Aphakic Infants

Rho-Kinase Inhibition Reduces Myofibroblast Differentiation and Proliferation of Scleral Fibroblasts Induced by Transforming Growth Factor β and Experimental Glaucoma

Noninvasive Assessment of Retinal Blood Flow Using a Novel Handheld Laser Speckle Contrast Imager

Hyperreflective Intraretinal Foci as an OCT Biomarker of Retinal Inflammation in Diabetic Macular Edema

Author Response: Hyperreflective Intraretinal Foci as an OCT Biomarker of Retinal Inflammation in Diabetic Macular Edema

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