Eye Anatomy and Disorders

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Special Issue September 2021

High-Fluence Accelerated Epithelium-Off Corneal Cross-Linking Protocol Provides Dresden Protocol–Like Corneal Strengthening

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Reyhaneh Abrishamchi; Hormoz Abdshahzadeh; Mark Hillen; Nikki Hafezi; Emilio A. Torres-Netto; Ioannis M. Aslanides; Shihao Chen; J. Bradley Randleman; Farhad Hafezi
TAGS: cornea, corneal collagen cross-linking, epithelium, chiari malformation type ii
Trans. Vis. Sci. Tech.. 2021; 10(5):10. doi: https://doi.org/10.1167/tvst.10.5.10

Anatomy and Pathology/Oncology September 2021

Dual Inhibition of Histone Deacetylases and the Mechanistic Target of Rapamycin Promotes Apoptosis in Cell Line Models of Uveal Melanoma

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Ruchi P. Patel; Joanna R. Thomas; Katherine M. Curt; Christina M. Fitzsimmons; Pedro J. Batista; Susan E. Bates; Michael M. Gottesman; Robert W. Robey
TAGS: apoptosis, cell lines, histone deacetylase, intraocular melanoma, mtor inhibitors, mtor serine-threonine kinases, rapamycin, romidepsin, proteins
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):16. doi: https://doi.org/10.1167/iovs.62.12.16

Includes: Supplemental Content

Cornea September 2021

Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy

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Rajalekshmy Shyam; Diego G. Ogando; Moonjung Choi; Paloma B. Liton; Joseph A. Bonanno
TAGS: animal model, autophagy, cornea, endothelial cells, endothelium, impairment, mitochondria, mitoq compound, pathophysiology, proteins
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):15. doi: https://doi.org/10.1167/iovs.62.12.15

Includes: Supplemental Content

Retina September 2021

Retinal Degeneration Caused by Ago2 Disruption

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Xue-Jiao Chen; Chang-Jun Zhang; Ya-Han Wang; Zi-Bing Jin
TAGS: mice, retina, retinal degeneration, micrornas
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):14. doi: https://doi.org/10.1167/iovs.62.12.14

Includes: Supplemental Content

Special Issue September 2021

Long-Term Study of Corneal Stroma and Endothelium on Structure and Cells After Genipin Treatment of Rabbit Corneas

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Wenjing Song; Yu Cheng; Xiaoming Yan; Songlin Yang
TAGS: cornea, corneal stroma, endothelium, oryctolagus cuniculus, ultraviolet a radiation, longitudinal studies
Trans. Vis. Sci. Tech.. 2021; 10(5):9. doi: https://doi.org/10.1167/tvst.10.5.9

Immunology and Microbiology September 2021

Ocular Surface Microbiota in Diabetic Patients With Dry Eye Disease

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Zhang Zhang; Xinrong Zou; Wenwen Xue; Pei Zhang; Shanshan Wang; Haidong Zou
TAGS: diabetes mellitus, dry eye syndromes, microbiome
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):13. doi: https://doi.org/10.1167/iovs.62.12.13

Includes: Supplemental Content

Articles September 2021

Deep-Learning–Based Pre-Diagnosis Assessment Module for Retinal Photographs: A Multicenter Study

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Vincent Yuen; Anran Ran; Jian Shi; Kaiser Sham; Dawei Yang; Victor T. T. Chan; Raymond Chan; Jason C. Yam; Clement C. Tham; Gareth J. McKay; Michael A. Williams; Leopold Schmetterer; Ching-Yu Cheng; Vincent Mok; Christopher L. Chen; Tien Y. Wong; Carol Y. Cheung
TAGS: datasets, deep learning, eye, handedness, image quality, multicenter studies, macula lutea, optics, eye diseases
Trans. Vis. Sci. Tech.. 2021; 10(11):16. doi: https://doi.org/10.1167/tvst.10.11.16

Includes: Multimedia, Supplemental Content

Articles September 2021

AAV-Mediated Expression of Human VEGF, TNF-α, and IL-6 Induces Retinal Pathology in Mice

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Carina M. Weigelt; Holger Fuchs; Tanja Schönberger; Birgit Stierstorfer; Benjamin Strobel; Thorsten Lamla; Thomas Ciossek; Remko A. Bakker; Norbert H. Redemann
TAGS: eye, interleukin-6, mice, retinal diseases, tumor necrosis factors, vascular endothelial growth factor a, injections, pathology, inflammation, retina
Trans. Vis. Sci. Tech.. 2021; 10(11):15. doi: https://doi.org/10.1167/tvst.10.11.15

Includes: Supplemental Content

Articles September 2021

In Vivo Efficacy of Imatinib Mesylate, a Tyrosine Kinase Inhibitor, in the Treatment of Chemically Induced Dry Eye in Animal Models

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Yi-Yong Baek; Bokyung Sung; Jun-Sub Choi; Hyeon-Kyu Go; Do-Hyung Kim; Joon Young Hyon; Ji Chang You
TAGS: animal model, dry eye syndromes, imatinib mesylate, protein-tyrosine kinase inhibitor, bronchioloalveolar carcinoma, blood alcohol concentration
Trans. Vis. Sci. Tech.. 2021; 10(11):14. doi: https://doi.org/10.1167/tvst.10.11.14

Article September 2021

Perceptual influence of auditory pitch on motion speed

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Gangsheng Zhang; Wei Wang; Jue Qu; Hengwei Li; Xincheng Song; Qingli Wang
TAGS: motion, judgment, perception
Journal of Vision. 2021; 21(10):11. doi: https://doi.org/10.1167/jov.21.10.11

Articles September 2021

Comparison of Corneal Irregularity After Recurrent and Primary Pterygium Surgery Using Fourier Harmonic Analysis

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Takashi Ono; Yosai Mori; Ryohei Nejima; Takuya Iwasaki; Takashi Miyai; Makoto Aihara; Kazunori Miyata
TAGS: cornea, harmonics, pterygium, recurrence, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2021; 10(11):13. doi: https://doi.org/10.1167/tvst.10.11.13

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology September 2021

Binocular Integration of Perceptually Suppressed Visual Information in Amblyopia

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Amy Chow; Andrew E. Silva; Katelyn Tsang; Gabriel Ng; Cindy Ho; Benjamin Thompson
TAGS: amblyopia, eye, motion
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):11. doi: https://doi.org/10.1167/iovs.62.12.11

Article September 2021

Local and global context repetitions in contextual cueing

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Nils Bergmann; Anna Schubö
TAGS: attention, learning, reaction time, reward, color, use techniques of reflection and clarification in communication
Journal of Vision. 2021; 21(10):9. doi: https://doi.org/10.1167/jov.21.10.9

Glaucoma September 2021

Binocular Interactions in Glaucoma Patients With Nonoverlapping Visual Field Defects: Contrast Summation, Rivalry, and Phase Combination

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Catarina A. R. João; Lorenzo Scanferla; Nomdo M. Jansonius
TAGS: eye, glaucoma, summation, vision, visual field defects
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):9. doi: https://doi.org/10.1167/iovs.62.12.9

Retina September 2021

Oxidative Stress Resistance 1 Gene Therapy Retards Neurodegeneration in the rd1 Mutant Mouse Model of Retinopathy

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Bhubanananda Sahu; Laura Moreno Leon; Wei Zhang; Nikita Puranik; Ramesh Periasamy; Hemant Khanna; Michael Volkert
TAGS: gene therapy, injections, mice, nerve degeneration, oxidative stress, retinal degeneration, retinal diseases, photoreceptors, caspases, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):8. doi: https://doi.org/10.1167/iovs.62.12.8

Includes: Supplemental Content

Glaucoma September 2021

Using CRISPR Interference as a Therapeutic Approach to Treat TGFβ2-Induced Ocular Hypertension and Glaucoma

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Naga Pradeep Rayana; Chenna Kesavulu Sugali; Jiannong Dai; Michael Peng; Shaohui Liu; Yucheng Zhang; Jun Wan; Weiming Mao
TAGS: crispr, eye, glaucoma, mice, ocular hypertension, cytomegalovirus, lentiviral vector, adenoviruses, genes
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):7. doi: https://doi.org/10.1167/iovs.62.12.7

Includes: Supplemental Content

Glaucoma September 2021

U-Shaped Effect of Blood Pressure on Structural OCT Metrics and Retinal Perfusion in Ophthalmologically Healthy Subjects

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Konstantinos Pappelis; Nomdo M. Jansonius
TAGS: blood pressure, glaucoma, homeostasis, hypotension, perfusion, vascular flow, ventricular rate rapid, mediation analysis, hypertension, did not receive therapy or drug
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):5. doi: https://doi.org/10.1167/iovs.62.12.5

Includes: Supplemental Content

Cornea September 2021

Mitochondrial Targeting of the Ammonia-Sensitive Uncoupler SLC4A11 by the Chaperone-Mediated Carrier Pathway in Corneal Endothelium

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Moonjung Choi; Joseph A. Bonanno
TAGS: hsp90 heat-shock proteins, mitochondria, molecular chaperones, ammonia
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):4. doi: https://doi.org/10.1167/iovs.62.12.4

Includes: Supplemental Content

Glaucoma September 2021

The Relationship Between Optic Disc and Retinal Artery Position and Glaucomatous Visual Field Progression

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Yuri Fujino; Ryo Asaoka; Hiroshi Murata; Takehiro Yamashita
TAGS: central retinal artery, glaucoma, intraocular pressure, optic disk, retina, visual fields, maximum tolerated dose
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):6. doi: https://doi.org/10.1167/iovs.62.12.6

Articles September 2021

Aqueous Cytokine Levels Are Associated With Progression of Peripheral Anterior Synechiae After Descemet Stripping Automated Endothelial Keratoplasty

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Yuki Kusano; Takefumi Yamaguchi; Sota Nishisako; Takehiro Matsumura; Masaki Fukui; Kazunari Higa; Toshihiro Inoue; Jun Shimazaki
TAGS: cytokine, descemet stripping endothelial keratoplasty, isolated tumor cells, peripheral anterior synechiae, protein measurement, total, eye
Trans. Vis. Sci. Tech.. 2021; 10(11):12. doi: https://doi.org/10.1167/tvst.10.11.12

Includes: Supplemental Content

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High-Fluence Accelerated Epithelium-Off Corneal Cross-Linking Protocol Provides Dresden Protocol–Like Corneal Strengthening

Dual Inhibition of Histone Deacetylases and the Mechanistic Target of Rapamycin Promotes Apoptosis in Cell Line Models of Uveal Melanoma

Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy

Retinal Degeneration Caused by Ago2 Disruption

Long-Term Study of Corneal Stroma and Endothelium on Structure and Cells After Genipin Treatment of Rabbit Corneas

Ocular Surface Microbiota in Diabetic Patients With Dry Eye Disease

Deep-Learning–Based Pre-Diagnosis Assessment Module for Retinal Photographs: A Multicenter Study

AAV-Mediated Expression of Human VEGF, TNF-α, and IL-6 Induces Retinal Pathology in Mice

In Vivo Efficacy of Imatinib Mesylate, a Tyrosine Kinase Inhibitor, in the Treatment of Chemically Induced Dry Eye in Animal Models

Perceptual influence of auditory pitch on motion speed

Comparison of Corneal Irregularity After Recurrent and Primary Pterygium Surgery Using Fourier Harmonic Analysis

Binocular Integration of Perceptually Suppressed Visual Information in Amblyopia

Local and global context repetitions in contextual cueing

Binocular Interactions in Glaucoma Patients With Nonoverlapping Visual Field Defects: Contrast Summation, Rivalry, and Phase Combination

Oxidative Stress Resistance 1 Gene Therapy Retards Neurodegeneration in the rd1 Mutant Mouse Model of Retinopathy

Using CRISPR Interference as a Therapeutic Approach to Treat TGFβ2-Induced Ocular Hypertension and Glaucoma

U-Shaped Effect of Blood Pressure on Structural OCT Metrics and Retinal Perfusion in Ophthalmologically Healthy Subjects

Mitochondrial Targeting of the Ammonia-Sensitive Uncoupler SLC4A11 by the Chaperone-Mediated Carrier Pathway in Corneal Endothelium

The Relationship Between Optic Disc and Retinal Artery Position and Glaucomatous Visual Field Progression

Aqueous Cytokine Levels Are Associated With Progression of Peripheral Anterior Synechiae After Descemet Stripping Automated Endothelial Keratoplasty

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