Eye Anatomy and Disorders

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Cornea October 2019

Hyperglycemia Suppresses Age-Related Increases in Corneal Peripheral Sensory Nerves in Wistar Bon Kobori (WBN/Kob) Rats

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Kiyokazu Ozaki; Yui Terayama; Tetsuro Matsuura
TAGS: cornea, hyperglycemia, neurons, rats, sensory nerves, diabetes mellitus
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4151-4158. doi: 10.1167/iovs.19-28060

Glaucoma October 2019

Association of Corneal Hysteresis With Lamina Cribrosa Curvature in Primary Open Angle Glaucoma

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Kyoung Min Lee; Tae-Woo Kim; Eun Ji Lee; Michaël J. A. Girard; Jean Martial Mari; Robert N. Weinreb
TAGS: cornea, corneal hysteresis, cribriform plate, genu varum, open-angle glaucoma, eye, glaucoma, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4171-4177. doi: 10.1167/iovs.19-27087

Includes: Supplemental Content

Retina October 2019

Blast Preconditioning Protects Retinal Ganglion Cells and Reveals Targets for Prevention of Neurodegeneration Following Blast-Mediated Traumatic Brian Injury

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Matthew M. Harper; Addison W. Woll; Lucy P. Evans; Michael Delcau; Abhigna Akurathi; Adam Hedberg-Buenz; Dana A. Soukup; Nickolas Boehme; Marco M. Hefti; Laura M. Dutca; Michael G. Anderson; Alexander G. Bassuk
TAGS: basic local alignment search tool, blast injuries, mice, wounds and injuries, nerve degeneration, retinal ganglion cells, prevention, rna
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4159-4170. doi: 10.1167/iovs.19-27565

Includes: Supplemental Content

Glaucoma October 2019

The Relationship Between Scleral Strain Change and Differential Cumulative Intraocular Pressure Exposure in the Nonhuman Primate Chronic Ocular Hypertension Model

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Massimo A. Fazio; Michael J. A. Girard; Wonyul Lee; Jeffrey S. Morris; Claude F. Burgoyne; J. Crawford Downs
TAGS: eye, intraocular pressure, ocular hypertension, sclera, primates
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4141-4150. doi: 10.1167/iovs.19-27060

Visual Psychophysics and Physiological Optics October 2019

Emmetropia Is Maintained Despite Continued Eye Growth From 16 to 18 Years of Age

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Lene A. Hagen; Stuart J. Gilson; Muhammad Nadeem Akram; Rigmor C. Baraas
TAGS: adolescent, biometry, emmetropia, eye, follow-up, refractive errors, cholecalciferol, myopia, hyperopia, lens, crystalline
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4178-4186. doi: 10.1167/iovs.19-27289

Biochemistry and Molecular Biology October 2019

Elevated Endogenous SDHA Drives Pathological Metabolism in Highly Metastatic Uveal Melanoma

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Chandrani Chattopadhyay; Junna Oba; Jason Roszik; Joseph R. Marszalek; Ken Chen; Yuan Qi; Karina Eterovic; A. Gordon Robertson; Jared K. Burks; Tara A. McCannel; Elizabeth A. Grimm; Scott E. Woodman
TAGS: genes, intraocular melanoma, metabolism, neoplasms, sdha gene, cancer, cell lines, monosomy, mitomycin, mitochondria
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4187-4195. doi: 10.1167/iovs.19-28082

Includes: Supplemental Content

Retina October 2019

Induced Expression of VEGFC , ANGPT , and EFNB2 and Their Receptors Characterizes Neovascularization in Proliferative Diabetic Retinopathy

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Yaping Li; Dong Chen; Luguo Sun; Yannan Wu; Ying Zou; Chen Liang; Yongli Bao; Jingwen Yi; Yu Zhang; Jing Hou; Zhen Li; Fengyun Yu; Yanxin Huang; Chunlei Yu; Lei Liu; Zaoxia Liu; Yi Zhang; Yuxin Li
TAGS: diabetes mellitus, type 2, genes, neovascularization, pathologic, proliferative diabetic retinopathy, retina, vascular endothelial growth factor c, gene expression, vascular endothelial growth factor a, rna, growth factor
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4084-4096. doi: 10.1167/iovs.19-26767

Includes: Supplemental Content

Physiology and Pharmacology October 2019

Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow

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Evan A. Thackaberry; Yi Zhou; Christina L. Zuch de Zafra; Germaine Fuh; Chingwei V. Lee; Sarah Sanowar; John B. Ridgway; Aija M. Kusi; Cindy Farman; Helen Booler; Daniel Sheinson; Carol A. Rasmussen; Paul E. Miller; Eric Wakshull; Minhong Yan; Vladimir Bantseev
TAGS: antibodies, anti-vascular endothelial growth factor therapy, aqueous humor, eye, glaucoma, intraocular pressure, macaca fascicularis, primates, signal transduction, mice
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4097-4108. doi: 10.1167/iovs.18-26349

Retina October 2019

Characteristics and Utility of Fundus Autofluorescence in Congenital Aniridia Using Scanning Laser Ophthalmoscopy

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Erlend C. S. Landsend; Hilde R. Pedersen; Øygunn A. Utheim; Corina S. Rueegg; Rigmor C. Baraas; Neil Lagali; Ragnheidur Bragadóttir; Morten C. Moe; Tor P. Utheim
TAGS: aniridia, foveal hypoplasia, fundus autofluorescence imaging, scanning laser ophthalmoscopy
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4120-4128. doi: 10.1167/iovs.19-26994

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology October 2019

Differential Experience-Dependent Plasticity of Form and Motion Mechanisms in Anisometropic Amblyopia

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Sean I. Chen; Arvind Chandna; Spero Nicholas; Anthony M. Norcia
TAGS: amblyopia, anisometropia, anisometropic amblyopia, child, eye, motion, neuronal plasticity, evoked potentials, visual
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4109-4119. doi: 10.1167/iovs.19-27005

Includes: Supplemental Content

Cornea October 2019

Influence of Vitamin D on Corneal Epithelial Cell Desmosomes and Hemidesmosomes

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Xiaowen Lu; Mitchell A. Watsky
TAGS: corneal epithelial cells, corneal epithelium, desmosomes, hemidesmosomes, integrins, mice, proteins, vitamin d, cornea
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4074-4083. doi: 10.1167/iovs.19-27796

Includes: Supplemental Content

Visual Neuroscience September 2019

Reductions in Calcium Signaling Limit Inhibition to Diabetic Retinal Rod Bipolar Cells

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Johnnie M. Moore-Dotson; Erika D. Eggers
TAGS: amacrine cells, diabetes mellitus, gamma-aminobutyric acid, retinal bipolar cells, rod photoreceptors, diabetes mellitus, type 2
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):4063-4073. doi: 10.1167/iovs.19-27137

Physiology and Pharmacology September 2019

In Vivo Fluorescence Visualization of Anterior Chamber Injected Human Corneal Endothelial Cells Labeled With Quantum Dots

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Munetoyo Toda; Hiroshi Yukawa; Jun Yamada; Morio Ueno; Shigeru Kinoshita; Yoshinobu Baba; Junji Hamuro
TAGS: anterior chamber of eye, cornea, endothelial cells, eye, fluorescence, mice, quantum dots, diagnostic imaging, injections
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):4008-4020. doi: 10.1167/iovs.19-27788

Includes: Supplemental Content

Immunology and Microbiology September 2019

CCR6-Positive γδ T Cells Provide Protection Against Intracorneal HSV-1 Infection

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Steffani Fitzpatrick; Robert Lausch; Robert A. Barrington
TAGS: cornea, human herpesvirus 1, infection, t-lymphocytes, mice, interleukin-17
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3952-3962. doi: 10.1167/iovs.19-27810

Visual Neuroscience September 2019

The Detection Of Misrouting In Albinism: Evaluation of Different VEP Procedures in a Heterogeneous Cohort

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Charlotte C. Kruijt; Gerard C. de Wit; Herman E. Talsma; Nicoline E. Schalij-Delfos; Maria M. van Genderen
TAGS: albinism, cohort studies, evoked potentials, visual, heterogeneity
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3963-3969. doi: 10.1167/iovs.19-27364

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology September 2019

Abnormal Eye Position Signals in Interstitial Nucleus of Cajal in Monkeys With “A” Pattern Strabismus

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Adam Pallus; Michael Mustari; Mark M. G. Walton
TAGS: cercopithecidae, eye, strabismus, interstitial nucleus of cajal, neurons
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3970-3979. doi: 10.1167/iovs.19-27490

Cornea September 2019

Quantitative Studies of Muscleblind Proteins and Their Interaction With TCF4 RNA Foci Support Involvement in the Mechanism of Fuchs' Dystrophy

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Ziye Rong; Jiaxin Hu; David R. Corey; V. Vinod Mootha
TAGS: proteins, rna, cornea, body tissue
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3980-3991. doi: 10.1167/iovs.19-27641

Includes: Supplemental Content

Retina September 2019

Light Sensitivity Within Areas of Geographic Atrophy Secondary to Age-Related Macular Degeneration

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Maximilian Pfau; Leon von der Emde; Chantal Dysli; Sarah Thiele; Philipp T. Möller; Moritz Lindner; Jennifer Nadal; Matthias Schmid; Steffen Schmitz-Valckenberg; Frank G. Holz; Monika Fleckenstein
TAGS: age-related macular degeneration, atrophy, photophobia, false-positive results, perimetry, spectral-domain optical coherence tomography, frequency of responses
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3992-4001. doi: 10.1167/iovs.19-27178

Includes: Supplemental Content

Glaucoma September 2019

NOS3 Deletion in Cav1 Deficient Mice Decreases Drug Sensitivity to a Nitric Oxide Donor and Two Nitric Oxide Synthase Inhibitors

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Maomao Song; Liping Li; Yuan Lei; Xinghuai Sun
TAGS: donors, intraocular pressure, mice, nitric oxide, nitric oxide synthase, nitric oxide synthase inhibitors, cyclic gmp, ng-nitroarginine methyl ester, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):4002-4007. doi: 10.1167/iovs.19-27582

Includes: Supplemental Content

Lens September 2019

Connexin 50 and AQP0 are Essential in Maintaining Organization and Integrity of Lens Fibers

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Sumin Gu; Sondip Biswas; Luis Rodriguez; Zhen Li; Yuting Li; Manuel A. Riquelme; Wen Shi; Ke Wang; Thomas W. White; Matthew Reilly; Woo-Kuen Lo; Jean X. Jiang
TAGS: lens (device), lens, crystalline, gap junction protein, mice, personal integrity
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):4021-4032. doi: 10.1167/iovs.18-26270

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Hyperglycemia Suppresses Age-Related Increases in Corneal Peripheral Sensory Nerves in Wistar Bon Kobori (WBN/Kob) Rats

Association of Corneal Hysteresis With Lamina Cribrosa Curvature in Primary Open Angle Glaucoma

Blast Preconditioning Protects Retinal Ganglion Cells and Reveals Targets for Prevention of Neurodegeneration Following Blast-Mediated Traumatic Brian Injury

The Relationship Between Scleral Strain Change and Differential Cumulative Intraocular Pressure Exposure in the Nonhuman Primate Chronic Ocular Hypertension Model

Emmetropia Is Maintained Despite Continued Eye Growth From 16 to 18 Years of Age

Elevated Endogenous SDHA Drives Pathological Metabolism in Highly Metastatic Uveal Melanoma

Induced Expression of VEGFC , ANGPT , and EFNB2 and Their Receptors Characterizes Neovascularization in Proliferative Diabetic Retinopathy

Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow

Characteristics and Utility of Fundus Autofluorescence in Congenital Aniridia Using Scanning Laser Ophthalmoscopy

Differential Experience-Dependent Plasticity of Form and Motion Mechanisms in Anisometropic Amblyopia

Influence of Vitamin D on Corneal Epithelial Cell Desmosomes and Hemidesmosomes

Reductions in Calcium Signaling Limit Inhibition to Diabetic Retinal Rod Bipolar Cells

In Vivo Fluorescence Visualization of Anterior Chamber Injected Human Corneal Endothelial Cells Labeled With Quantum Dots

CCR6-Positive γδ T Cells Provide Protection Against Intracorneal HSV-1 Infection

The Detection Of Misrouting In Albinism: Evaluation of Different VEP Procedures in a Heterogeneous Cohort

Abnormal Eye Position Signals in Interstitial Nucleus of Cajal in Monkeys With “A” Pattern Strabismus

Quantitative Studies of Muscleblind Proteins and Their Interaction With TCF4 RNA Foci Support Involvement in the Mechanism of Fuchs' Dystrophy

Light Sensitivity Within Areas of Geographic Atrophy Secondary to Age-Related Macular Degeneration

NOS3 Deletion in Cav1 Deficient Mice Decreases Drug Sensitivity to a Nitric Oxide Donor and Two Nitric Oxide Synthase Inhibitors

Connexin 50 and AQP0 are Essential in Maintaining Organization and Integrity of Lens Fibers

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