Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

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Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology April 2025

Multiterminal En Plaque Motor Endplates in Extraocular Muscles Are Conserved Across Vertebrate Species

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Jing-Xia Liu; Abraha Kahsay; Nils Dennhag; Jonas von Hofsten; Fatima Pedrosa Domellöf
TAGS: mice, motor endplate, muscle of orbit, neuromuscular junction, vertebrates, zebrafish, oryctolagus cuniculus, antibodies, muscle
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):77. https://doi.org/10.1167/iovs.66.4.77

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology April 2025

The Influence of Changes in Microglia Development on the Plasticity of the Developing Visual Cortex Circuit in Juvenile Mice

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Xuechun Wang; Kuan Li; Lingzhi Guo; Xinlong Liu; Yatu Guo; Wei Zhang
TAGS: mice, microglia, visual cortex, interneurons, neurons, small nuclear rna, child
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):45. https://doi.org/10.1167/iovs.66.4.45

Includes: Supplemental Content

Genetics April 2025

Clinical Spectrum and Molecular Characteristics of Inherited Ocular Diseases in a Cohort of Pediatric Patients With Infantile Nystagmus Syndrome

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Xiaoming Gong; Ian P. Boydstun; William T. Lawhon; Nancy N. Hanna; Palak B. Wall; Aaron Flickinger; E. Eugenie Hartmann; Richard W. Hertle
TAGS: cohort studies, eye diseases, genes, genetics, pathologic nystagmus, pediatrics, syndrome, genetic screening
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):39. https://doi.org/10.1167/iovs.66.4.39

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics April 2025

Temporal Contour Integration Deficits in Children With Amblyopia

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Yan-Ru Chen; Shu-Qi Jiang; Xiang-Yun Liu; Jun-Yun Zhang
TAGS: amblyopia, child
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):27. https://doi.org/10.1167/iovs.66.4.27

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology April 2025

Temporal Frequency Modulation of Binocular Balance in Normal and Amblyopic Vision

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Chenyan Zhou; Jiawei Zhou; Seung Hyun Min
TAGS: amblyopia, balance, device, equilibrium, eye, attention, vision, photopsia
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):8. https://doi.org/10.1167/iovs.66.4.8

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology March 2025

Gene Identification for Ocular Congenital Cranial Motor Neuron Disorders Using Human Sequencing, Zebrafish Screening, and Protein Binding Microarrays

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Julie A. Jurgens; Paola M. Matos Ruiz; Jessica King; Emma E. Foster; Lindsay Berube; Wai-Man Chan; Brenda J. Barry; Raehoon Jeong; Elisabeth Rothman; Mary C. Whitman; Sarah MacKinnon; Cristina Rivera-Quiles; Brandon M. Pratt; Teresa Easterbrooks; Fiona M. Mensching; Silvio Alessandro Di Gioia; Lynn Pais; Eleina M. England; Teresa de Berardinis; Adriano Magli; Feray Koc; Kazuhide Asakawa; Koichi Kawakami; Anne O'Donnell-Luria; David G. Hunter; Caroline D. Robson; Martha L. Bulyk; Elizabeth C. Engle
TAGS: cranium, genes, motor neurons, protein binding, screening, zebrafish, transcription factor, candidate disease gene, pathogenicity
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):62. https://doi.org/10.1167/iovs.66.3.62

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology March 2025

Distribution of Globe Excursions Within the Orbits Monitored by Eye Tracking Glasses in Ambulatory Subjects Engaged in Their Normal Daily Activities

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Yicen J. Zheng; Thomas N. Gentry; John R. Economides; Jonathan C. Horton
TAGS: eye, eyeglasses, eye-tracking, orbit, gaze
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):20. https://doi.org/10.1167/iovs.66.3.20

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology March 2025

One-Month-Old Rabbits Exhibit a Longer Postoperative Remodeling in Extraocular Muscles Compared to 3-Month-Old Rabbits

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Jiangtao Lou; Hailu Huang; Yiyi Peng; Chunxiao Wang; Meiping Xu; Xinping Yu
TAGS: muscle of orbit, oryctolagus cuniculus, postoperative care, surgical procedures, operative, embryo, russell-silver syndrome, surgery specialty, somatostatin receptor scintigraphy, preoperative care
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):12. https://doi.org/10.1167/iovs.66.3.12

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology February 2025

Chiasmal Decussation in Oculo-Cutaneous Albinism Type 8

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Maxence Rateaux; Smaïl Hadj-Rabia; Rémi Barrois; Olivia Zambrowski; Vincent Michaud; Ester Moreno-Artero; Dominique Bremond-Gignac; Sophie Javerzat; Matthieu P. Robert
TAGS: albinism
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):44. https://doi.org/10.1167/iovs.66.2.44

Letters to the Editor February 2025

Comment on: “Effects of Monocular Flicker on Binocular Imbalance in Amblyopic and Nonamblyopic Adults”

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Alexandre Reynaud
TAGS: adult, amblyopia, imbalance, photopsia
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):29. https://doi.org/10.1167/iovs.66.2.29

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology January 2025

Horizontal Gaze Tolerance and Its Effects on Visual Sensitivity in Glaucoma

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Takashi Nishida; Takuhei Shoji; Robert N. Weinreb; Saori Yamaguchi; Izumi Mine; Akane Kosaka; Kei Shinoda
TAGS: eye movement, gaze, glaucoma, adduction, optic disk, eye, abduction
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):59. https://doi.org/10.1167/iovs.66.1.59

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology January 2025

Simvastatin-Induced Ferroptosis in Orbital Fibroblasts in Graves’ Ophthalmopathy

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Lujue Wang; Yuan Li; Tongxin Niu; Jing Deng; Yuxian Shi; Yating Liu; Boding Tong; Xin Qi; Dan Cao; Yongguang Tao; Yunping Li
TAGS: ferroptosis, graves' ophthalmopathy, simvastatin, fibroblasts
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):56. https://doi.org/10.1167/iovs.66.1.56

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology January 2025

Eye Movements and the Intraorbital Subarachnoid Space: Potential Contribution of Altered Cerebrospinal Fluid Pumping in Optic Neuropathies

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Joseph L. Demer; Robert A. Clark; Soh Youn Suh; JoAnn A. Giaconi; Kouros Nouri-Mahdavi; Simon K. Law; Laura Bonelli; Anthony C. Arnold; Peter Quiros; Anne L. Coleman; Joseph Caprioli
TAGS: adduction, cerebrospinal fluid, eye, eye movement, magnetic resonance imaging, open-angle glaucoma, optic nerve, optic nerve disorders, subarachnoid space, volume
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):53. https://doi.org/10.1167/iovs.66.1.53

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology January 2025

Fixation Stability Deficits in Anisometropic Amblyopia

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Yusong Zhou; Wentong Yu; Qingqing Ye; Zixuan Xu; Yunsi He; Ying Yao; Yangfei Pang; Yudan Zhong; Qiuying Li; Lei Feng; Yun Wen; Xuan Qiu; Zhonghao Wang; Jinrong Li
TAGS: amblyopia, anisometropic amblyopia, eye, vision, contrast sensitivity, visual acuity
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):14. https://doi.org/10.1167/iovs.66.1.14

Includes: Supplemental Content

Clinical and Epidemiologic Research January 2025

Validating Rules for Defining No Improvement of Visual Acuity in Childhood Amblyopia

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Rui Wu; Ruth E. Manny; Jonathan M. Holmes; B. Michele Melia; Zhuokai Li; David K. Wallace; Eileen E. Birch; Raymond T. Kraker; Susan A. Cotter; on behalf of the Pediatric Eye Disease Investigator Group
TAGS: amblyopia, amblyopia, pediatric, visual acuity, false-negative results, false-positive results, visual analogue pain scale, eyeglasses, sensitivity analysis
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):4. https://doi.org/10.1167/iovs.66.1.4

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics December 2024

Serial Dependence in Smooth Pursuit Eye Movements of Preadolescent Children and Adults

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Bao Hong; Jing Chen; Wenjun Huang; Li Li
TAGS: adult, anisotropy, child, motion, pursuit, smooth, pre-teen, precision
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):37. https://doi.org/10.1167/iovs.65.14.37

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology December 2024

Evaluating Eye Tracking During Dichoptic Video Viewing With Varied Fellow Eye Contrasts in Amblyopia

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Ibrahim M. Quagraine; Jordan Murray; Gokce Busra Cakir; Sinem Balta Beylergil; Alexa Kaudy; Aasef G. Shaikh; Fatema F. Ghasia
TAGS: amblyopia, eye, eye-tracking, eye deviation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):11. https://doi.org/10.1167/iovs.65.14.11

Retina November 2024

Influencing Factors on Pupillary Light Responses as a Biomarker for Local Retinal Function in a Large Normative Cohort

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Ricarda Jendritza; Krunoslav Stingl; Torsten Strasser; Ronja Jung; Felix Tonagel; Paul Richter; Anton Sonntag; Tobias Peters; Helmut Wilhelm; Barbara Wilhelm; Carina Kelbsch
TAGS: biological markers, cardiac progenitor cells, cohort studies, pupil, pupil light reflex, retinal cone, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):3. https://doi.org/10.1167/iovs.65.6.3

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology November 2024

Fine Motor Skills, Reading Speed, and Self-Reported Quality of Life in Adults With Amblyopia and/or Strabismus

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Archayeeta Rakshit; Debasmita Majhi; Katrina L. Schmid; Vivek Warkad; David A. Atchison; Ann L. Webber
TAGS: adult, amblyopia, fine motor skills, quality of life, reading (activity), reading speed, self-report, strabismus, vision
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):48. https://doi.org/10.1167/iovs.65.13.48

Retinal Cell Biology November 2024

Blind But Alive – Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish

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Juliane Hammer; Paul Röppenack; Sarah Yousuf; Anja Machate; Marika Fischer; Stefan Hans; Michael Brand
TAGS: adult, zebrafish, phenotype, visual system, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):42. https://doi.org/10.1167/iovs.65.13.42

Includes: Supplemental Content

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Multiterminal En Plaque Motor Endplates in Extraocular Muscles Are Conserved Across Vertebrate Species

The Influence of Changes in Microglia Development on the Plasticity of the Developing Visual Cortex Circuit in Juvenile Mice

Clinical Spectrum and Molecular Characteristics of Inherited Ocular Diseases in a Cohort of Pediatric Patients With Infantile Nystagmus Syndrome

Temporal Contour Integration Deficits in Children With Amblyopia

Temporal Frequency Modulation of Binocular Balance in Normal and Amblyopic Vision

Gene Identification for Ocular Congenital Cranial Motor Neuron Disorders Using Human Sequencing, Zebrafish Screening, and Protein Binding Microarrays

Distribution of Globe Excursions Within the Orbits Monitored by Eye Tracking Glasses in Ambulatory Subjects Engaged in Their Normal Daily Activities

One-Month-Old Rabbits Exhibit a Longer Postoperative Remodeling in Extraocular Muscles Compared to 3-Month-Old Rabbits

Chiasmal Decussation in Oculo-Cutaneous Albinism Type 8

Comment on: “Effects of Monocular Flicker on Binocular Imbalance in Amblyopic and Nonamblyopic Adults”

Horizontal Gaze Tolerance and Its Effects on Visual Sensitivity in Glaucoma

Simvastatin-Induced Ferroptosis in Orbital Fibroblasts in Graves’ Ophthalmopathy

Eye Movements and the Intraorbital Subarachnoid Space: Potential Contribution of Altered Cerebrospinal Fluid Pumping in Optic Neuropathies

Fixation Stability Deficits in Anisometropic Amblyopia

Validating Rules for Defining No Improvement of Visual Acuity in Childhood Amblyopia

Serial Dependence in Smooth Pursuit Eye Movements of Preadolescent Children and Adults

Evaluating Eye Tracking During Dichoptic Video Viewing With Varied Fellow Eye Contrasts in Amblyopia

Influencing Factors on Pupillary Light Responses as a Biomarker for Local Retinal Function in a Large Normative Cohort

Fine Motor Skills, Reading Speed, and Self-Reported Quality of Life in Adults With Amblyopia and/or Strabismus

Blind But Alive – Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish

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