Imaging

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Retina August 2022

Dependence of Retinal Pigment Epithelium Integrity on the NRF2–Heme Oxygenase-1 Axis

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Yida Jiang; Li-Juan Duan; Jingbo Pi; Yun-Zheng Le; Guo-Hua Fong
TAGS: body tissue, heme, mice, oxidative stress, oxygenases, painful bladder syndrome, personal integrity, retinal pigment cell, retinal pigment epithelium, eye
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):30. doi: https://doi.org/10.1167/iovs.63.9.30

Includes: Supplemental Content

Retina August 2022

Quantification and Predictors of OCT-Based Macular Curvature and Dome-Shaped Configuration: Results From the UK Biobank

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Philipp L. Müller; Yuka Kihara; Abraham Olvera-Barrios; Alasdair N. Warwick; Catherine Egan; Katie M. Williams; Aaron Y. Lee; Adnan Tufail; for the UK Biobank Eyes and Vision Consortium
TAGS: biobanks, cohort studies, eye, myopia, refractive errors, diagnostic imaging, ethnic group, hyperopia, smoking in pregnancy, congenital abnormality
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):28. doi: https://doi.org/10.1167/iovs.63.9.28

Includes: Supplemental Content

Clinical Trials August 2022

Lateral Geniculate Nucleus Volume Determined on MRI Correlates With Corresponding Ganglion Cell Layer Loss in Acquired Human Postgeniculate Lesions

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Cyril Fabian Simmen; Fabienne Catherine Fierz; Lars Michels; Njoud Aldusary; Klara Landau; Marco Piccirelli; Ghislaine Lieselotte Traber
TAGS: ganglia, lateral geniculate body, magnetic resonance imaging, volume
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):18. doi: https://doi.org/10.1167/iovs.63.9.18

Clinical and Epidemiologic Research August 2022

Macular Layer Thickness and Effect of BMI, Body Fat, and Traditional Cardiovascular Risk Factors: The Tromsø Study

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Therese von Hanno; Live Lund Hareide; Lars Småbrekke; Bente Morseth; Monica Sneve; Maja Gran Erke; Ellisiv Bøgeberg Mathiesen; Geir Bertelsen
TAGS: body fat, body mass index procedure, heart disease risk factors, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):16. doi: https://doi.org/10.1167/iovs.63.9.16

Includes: Supplemental Content

Retina August 2022

Correlation of Diabetic Disease Severity to Degree of Quadrant Asymmetry in En Face OCTA Metrics

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Jesse J. Jung; Shen Yi Lim; Xavier Chan; Srinivas R. Sadda; Quan V. Hoang
TAGS: diabetes mellitus, diabetic retinopathy, eye, face, nonproliferative diabetic retinopathy, severity of illness, diagnostic imaging, parafoveal region
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):12. doi: https://doi.org/10.1167/iovs.63.9.12

Multidisciplinary Ophthalmic Imaging August 2022

Subcellular Comparison of Visible-Light Optical Coherence Tomography and Electron Microscopy in the Mouse Outer Retina

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Pooja Chauhan; Aaron M. Kho; Paul FitzGerald; Bradley Shibata; Vivek J. Srinivasan
TAGS: mice, optical coherence tomography, retina, visible light, embryonic lethal mutation
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):10. doi: https://doi.org/10.1167/iovs.63.9.10

Includes: Supplemental Content

Retina August 2022

Longitudinal Evaluation of Changes in Retinal Architecture Using Optical Coherence Tomography in Achromatopsia

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Magdalini Triantafylla; Eleni Papageorgiou; Mervyn G. Thomas; Rebecca McLean; Susanne Kohl; Viral Sheth; Zhanhan Tu; Frank A. Proudlock; Irene Gottlob
TAGS: achromatopsia, follow-up, optical coherence tomography, foveal hypoplasia, charcot-marie-tooth disease, orthodromic circus-movement tachycardia, child, genetics, molecular
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):6. doi: https://doi.org/10.1167/iovs.63.9.6

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging July 2022

Photoreceptor and Retinal Pigment Epithelium Relationships in Eyes With Vitelliform Macular Dystrophy Revealed by Multimodal Adaptive Optics Imaging

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Tao Liu; Nancy Aguilera; Andrew J. Bower; Joanne Li; Ehsan Ullah; Alfredo Dubra; Catherine Cukras; Brian P. Brooks; Brett G. Jeffrey; Robert B. Hufnagel; Laryssa A. Huryn; Wadih M. Zein; Johnny Tam
TAGS: diagnostic imaging, eye, retinal cone, vitelliform dystrophy, optics, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):27. doi: https://doi.org/10.1167/iovs.63.8.27

Includes: Supplemental Content

Clinical and Epidemiologic Research July 2022

Foveal Curvature and Its Associations in UK Biobank Participants

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Abraham Olvera-Barrios; Yuka Kihara; Yue Wu; Alasdair N. Warwick; Philipp L. Müller; Katie M. Williams; Alicja R. Rudnicka; Christopher G. Owen; Aaron Y. Lee; Catherine Egan; Adnan Tufail; on behalf of the UK Biobank Eyes and Vision Consortium
TAGS: biobanks, ethnic group, income, eye, astigmatism, fovea centralis
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):26. doi: https://doi.org/10.1167/iovs.63.8.26

Includes: Supplemental Content

Retina July 2022

Quantitative Evaluations of Posterior Staphylomas in Highly Myopic Eyes by Ultra-Widefield Optical Coherence Tomography

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Noriko Nakao; Tae Igarashi-Yokoi; Hiroyuki Takahashi; Shiqi Xie; Kosei Shinohara; Kyoko Ohno-Matsui
TAGS: eye, optical coherence tomography, staphyloma, shape
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):20. doi: https://doi.org/10.1167/iovs.63.8.20

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging July 2022

Functional Changes Within the Rod Inner Segment Ellipsoid in Wildtype Mice: An Optical Coherence Tomography and Electron Microscopy Study

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Bruce A. Berkowitz; Robert H. Podolsky; Karen Lins Childers; Tom Burgoyne; Giulia De Rossi; Haohua Qian; Robin Roberts; Ryan Katz; Rida Waseem; Cole Goodman
TAGS: mice, mitochondria, optical coherence tomography, rod photoreceptors, shape, signal intensity, embryonic lethal mutation
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):8. doi: https://doi.org/10.1167/iovs.63.8.8

Includes: Supplemental Content

Retina June 2022

Retinal Oxygen Delivery and Metabolism Response to Hyperoxia During Bilateral Common Carotid Artery Occlusion in Rats

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Sophie Leahy; Nathanael Matei; Norman P. Blair; Mahnaz Shahidi
TAGS: common carotid artery, hyperoxia, metabolism, oxygen delivery, rats, oxygen, vascular flow
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):30. doi: https://doi.org/10.1167/iovs.63.6.30

Retina June 2022

Characteristics of the Optic Nerve Head in Myopic Eyes Using Swept-Source Optical Coherence Tomography

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Dan Cheng; Kaiming Ruan; Minhui Wu; Yilin Qiao; Weiqian Gao; Hengli Lian; Meixiao Shen; Fangjun Bao; Yizeng Yang; Jun Zhu; Haiying Huang; Xianwei Meng; Lijun Shen; Yufeng Ye
TAGS: eye, myopia, optic disk, optical coherence tomography, microvascular network
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):20. doi: https://doi.org/10.1167/iovs.63.6.20

Retina June 2022

Exploring Reticular Pseudodrusen Extent and Impact on Mesopic Visual Sensitivity in Intermediate Age-Related Macular Degeneration

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Himeesh Kumar; Robyn H. Guymer; Lauren A. B. Hodgson; Xavier Hadoux; Zhichao Wu
TAGS: age-related macular degeneration, drusen, eye, reticular pseudodrusen, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):14. doi: https://doi.org/10.1167/iovs.63.6.14

Includes: Supplemental Content

Retina May 2022

High-Density Optical Coherence Tomography Analysis Provides Insights Into Early/Intermediate Age-Related Macular Degeneration Retinal Layer Changes

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Matt Trinh; Michael Kalloniatis; David Alonso-Caneiro; Lisa Nivison-Smith
TAGS: age-related macular degeneration, eye, optical coherence tomography, retina, correlation studies, propensity score method, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):36. doi: https://doi.org/10.1167/iovs.63.5.36

Includes: Supplemental Content

Visual Neuroscience May 2022

The Association Between Acquired Color Deficiency and PET Imaging of Neurodegeneration in Mild Cognitive Impairment and Alzheimer Disease

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Kallene Summer Moreira Vidal; Diego Decleva; Mirella Telles Salgueiro Barboni; Balàzs Vince Nagy; Paulo Augusto Hidalgo de Menezes; Avinash Aher; Artur Martins Coutinho; Paula Squarzoni; Daniele de Paula Faria; Fabio Luis de Souza Duran; Carlos Alberto Buchpiguel; Jan Kremers; Geraldo Busatto Filho; Dora Fix Ventura
TAGS: alzheimer's disease, brain, color, color vision, electroretinography, heart failure, minimal cognitive impairment, nerve degeneration, positron-emission tomography
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):20. doi: https://doi.org/10.1167/iovs.63.5.20

Includes: Supplemental Content

Retina April 2022

Depletion of miR-96 Delays, But Does Not Arrest, Photoreceptor Development in Mice

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Lue Xiang; Juan Zhang; Feng-Qin Rao; Qiao-Li Yang; Hui-Yi Zeng; Sheng-Hai Huang; Zhen-Xiang Xie; Ji-Neng Lv; Dan Lin; Xue-Jiao Chen; Kun-Chao Wu; Fan Lu; Xiu-Feng Huang; Qi Chen
TAGS: mice, photoreceptors, developmental delay
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):24. doi: https://doi.org/10.1167/iovs.63.4.24

Includes: Supplemental Content

Retina April 2022

Impact of Reference Center Choice on Adaptive Optics Imaging Cone Mosaic Analysis

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Danial Roshandel; Danuta M. Sampson; David A. Mackey; Fred K. Chen
TAGS: diagnostic imaging, mosaicism, optics, retinal cone, fovea centralis
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):12. doi: https://doi.org/10.1167/iovs.63.4.12

Includes: Supplemental Content

Retina April 2022

Function of the Retinal Pigment Epithelium in Patients With Neurofibromatosis Type 1

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Romain Touzé; Marc M. Abitbol; Dominique Bremond-Gignac; Matthieu P. Robert
TAGS: electrooculography, neurofibromatosis 1, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):6. doi: https://doi.org/10.1167/iovs.63.4.6

Includes: Supplemental Content

Retinal Cell Biology April 2022

Identification of CD157-Positive Vascular Endothelial Stem Cells in Mouse Retinal and Choroidal Vessels: Fluorescence-Activated Cell Sorting Analysis

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Taku Wakabayashi; Hisamichi Naito; Tomohiro Iba; Kohji Nishida; Nobuyuki Takakura
TAGS: cell separation, choroid, endothelium, fluorescence, mice, retina, stem cells, electroconvulsive therapy, cd31 antigens, epidural cortical stimulation
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):5. doi: https://doi.org/10.1167/iovs.63.4.5

Includes: Supplemental Content

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Dependence of Retinal Pigment Epithelium Integrity on the NRF2–Heme Oxygenase-1 Axis

Quantification and Predictors of OCT-Based Macular Curvature and Dome-Shaped Configuration: Results From the UK Biobank

Lateral Geniculate Nucleus Volume Determined on MRI Correlates With Corresponding Ganglion Cell Layer Loss in Acquired Human Postgeniculate Lesions

Macular Layer Thickness and Effect of BMI, Body Fat, and Traditional Cardiovascular Risk Factors: The Tromsø Study

Correlation of Diabetic Disease Severity to Degree of Quadrant Asymmetry in En Face OCTA Metrics

Subcellular Comparison of Visible-Light Optical Coherence Tomography and Electron Microscopy in the Mouse Outer Retina

Longitudinal Evaluation of Changes in Retinal Architecture Using Optical Coherence Tomography in Achromatopsia

Photoreceptor and Retinal Pigment Epithelium Relationships in Eyes With Vitelliform Macular Dystrophy Revealed by Multimodal Adaptive Optics Imaging

Foveal Curvature and Its Associations in UK Biobank Participants

Quantitative Evaluations of Posterior Staphylomas in Highly Myopic Eyes by Ultra-Widefield Optical Coherence Tomography

Functional Changes Within the Rod Inner Segment Ellipsoid in Wildtype Mice: An Optical Coherence Tomography and Electron Microscopy Study

Retinal Oxygen Delivery and Metabolism Response to Hyperoxia During Bilateral Common Carotid Artery Occlusion in Rats

Characteristics of the Optic Nerve Head in Myopic Eyes Using Swept-Source Optical Coherence Tomography

Exploring Reticular Pseudodrusen Extent and Impact on Mesopic Visual Sensitivity in Intermediate Age-Related Macular Degeneration

High-Density Optical Coherence Tomography Analysis Provides Insights Into Early/Intermediate Age-Related Macular Degeneration Retinal Layer Changes

The Association Between Acquired Color Deficiency and PET Imaging of Neurodegeneration in Mild Cognitive Impairment and Alzheimer Disease

Depletion of miR-96 Delays, But Does Not Arrest, Photoreceptor Development in Mice

Impact of Reference Center Choice on Adaptive Optics Imaging Cone Mosaic Analysis

Function of the Retinal Pigment Epithelium in Patients With Neurofibromatosis Type 1

Identification of CD157-Positive Vascular Endothelial Stem Cells in Mouse Retinal and Choroidal Vessels: Fluorescence-Activated Cell Sorting Analysis

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