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Clinical and Epidemiologic Research September 2022

Longitudinal Changes in Lens Thickness and Lens Power Among Persistent Non-Myopic and Myopic Children

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Xiaotong Han; Ruilin Xiong; Ling Jin; Qianyun Chen; Decai Wang; Shida Chen; Xiang Chen; Jason Ha; Yuting Li; Yabin Qu; Rong Lin; Mingguang He; Ian G. Morgan; Yangfa Zeng; Yizhi Liu
TAGS: child, eye development, lens, crystalline, myopia, persistence, follow-up
Invest. Ophthalmol. Vis. Sci.. 2022; 63(10):10. doi: https://doi.org/10.1167/iovs.63.10.10

Includes: Supplemental Content

Lens September 2022

Deficiency of Jamc Leads to Congenital Nuclear Cataract and Activates the Unfolded Protein Response in Mouse Lenses

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Jiani Li; Xuhua Tan; Qihang Sun; Xuri Li; Rongyuan Chen; Lixia Luo
TAGS: cataract, cataract, nuclear, lens (device), lens, crystalline, mice, unfolded protein response
Invest. Ophthalmol. Vis. Sci.. 2022; 63(10):1. doi: https://doi.org/10.1167/iovs.63.10.1

Includes: Supplemental Content

Biochemistry and Molecular Biology August 2022

Gene Expression Signatures of Contact Lens-Induced Myopia in Guinea Pig Retinal Pigment Epithelium

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So Goto; Sandra E. Muroy; Yan Zhang; Kaoru Saijo; Sree Rohit Raj Kolora; Qiurong Zhu; Christine F. Wildsoet
TAGS: eye, gene expression, guinea, lens (device), lens, crystalline, myopia, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):25. doi: https://doi.org/10.1167/iovs.63.9.25

Includes: Supplemental Content

Clinical and Epidemiologic Research August 2022

Ambient Air Pollution and Age-Related Eye Disease: A Systematic Review and Meta-Analysis

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Alyssa Grant; Gareth Leung; Ellen E. Freeman
TAGS: air pollution, eye diseases, meta-analysis, systematic reviews, glaucoma, cataract, air pollutants
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):17. doi: https://doi.org/10.1167/iovs.63.9.17

Includes: Supplemental Content

Lens July 2022

Lens Aquaporin-5 Inserts Into Bovine Fiber Cell Plasma Membranes Via Unconventional Protein Secretion

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Romell B. Gletten; Lee S. Cantrell; Sujoy Bhattacharya; Kevin L. Schey
TAGS: cattle, cell membrane, lens (device), lens, crystalline, water channels, protein secretion, cytoplasmic vesicles
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):5. doi: https://doi.org/10.1167/iovs.63.8.5

Includes: Supplemental Content

Lens June 2022

TFEB-Mediated Lysosomal Restoration Alleviates High Glucose-Induced Cataracts Via Attenuating Oxidative Stress

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Yan Sun; Xiaoran Wang; Baoxin Chen; Mi Huang; Pengjuan Ma; Lang Xiong; Jingqi Huang; Jieping Chen; Shan Huang; Yizhi Liu
TAGS: autophagy, cataract, diabetes mellitus, glucose, lens (device), lens, crystalline, oxidative stress, proteins, western blotting, pathophysiology
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):26. doi: https://doi.org/10.1167/iovs.63.6.26

Includes: Supplemental Content

Genetics June 2022

Sonic Hedgehog Intron Variant Associated With an Unusual Pediatric Cortical Cataract

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Terri L. Young; Kristina N. Whisenhunt; Sarah M. LaMartina; Alex W. Hewitt; David A. Mackey; Stuart W. Tompson
TAGS: cataract, childhood, cortical cataract, introns, pediatrics, shh gene, enhancer of transcription, genes, genetic pedigree
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):25. doi: https://doi.org/10.1167/iovs.63.6.25

Lens May 2022

Oxysterol Compounds in Mouse Mutant αA- and αB-Crystallin Lenses Can Improve the Optical Properties of the Lens

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Kehao Wang; Masato Hoshino; Kentaro Uesugi; Naoto Yagi; Barbara K. Pierscionek; Usha P. Andley
TAGS: crystallins, lens (device), lens, crystalline, mice, optics, oxysterols, refractive index, alpha-crystallin b chain, cataract
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):15. doi: https://doi.org/10.1167/iovs.63.5.15

Includes: Supplemental Content

Lens April 2022

Znhit1 Regulates p21 Cip1 to Control Mouse Lens Differentiation

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Juan Lu; Jianhong An; Jiawei Wang; Xiaowen Cao; Yuqing Cao; Chengjie Huang; Shiming Jiao; Dongsheng Yan; Xinhua Lin; Xiangtian Zhou
TAGS: lens (device), lens, crystalline, mice
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):18. doi: https://doi.org/10.1167/iovs.63.4.18

Includes: Supplemental Content

Lens April 2022

The E3 Ligase RNF157 Inhibits Lens Epithelial Cell Apoptosis by Negatively Regulating p53 in Age-Related Cataracts

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Tiantian Qi; Ruihua Jing; Bo Ma; Conghui Hu; Chan Wen; Yongping Shao; Cheng Pei
TAGS: apoptosis, cataract, cataract, senile, hydrogen peroxide, ubiquitin-protein ligases, lens, crystalline, lens (device), proteins, lens epithelial cell
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):11. doi: https://doi.org/10.1167/iovs.63.4.11

Includes: Supplemental Content

Lens April 2022

Patterns of Crystallin Gene Expression in Differentiation State Specific Regions of the Embryonic Chicken Lens

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Zhiwei Ma; Daniel Chauss; Joshua Disatham; Xiaodong Jiao; Lisa Ann Brennan; A. Sue Menko; Marc Kantorow; J. Fielding Hejtmancik
TAGS: crystallins, genes, lens (device), lens, crystalline, chickens, gene expression, embryo
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):8. doi: https://doi.org/10.1167/iovs.63.4.8

Includes: Supplemental Content

Glaucoma March 2022

RNA Sequencing of Lens Capsular Epithelium Implicates Novel Pathways in Pseudoexfoliation Syndrome

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Sean Mullany; Henry Marshall; Tiger Zhou; Daniel Thomson; Joshua M. Schmidt; Ayub Qassim; Lachlan S. W. Knight; Georgina Hollitt; Ella C. Berry; Thi Nguyen; Minh-Son To; David Dimasi; Abraham Kuot; Joshua Dubowsky; Rhys Fogarty; Michelle Sun; Luke Chehade; Shilpa Kuruvilla; Devaraj Supramaniam; James Breen; Shiwani Sharma; John Landers; Stewart Lake; Richard A. Mills; Mark M. Hassall; Weng O. Chan; Sonja Klebe; Emmanuelle Souzeau; Owen M. Siggs; Jamie E. Craig
TAGS: genes, lens, crystalline, epithelium, exfoliation syndrome, sequence analysis, rna
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):26. doi: https://doi.org/10.1167/iovs.63.3.26

Includes: Supplemental Content

Anatomy and Pathology/Oncology March 2022

Axial Elongation During Short-Term Accommodation in Myopic and Nonmyopic Children

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Rohan P. J. Hughes; Scott A. Read; Michael J. Collins; Stephen J. Vincent
TAGS: child, visual accommodation
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):12. doi: https://doi.org/10.1167/iovs.63.3.12

Retina March 2022

Aqueous Humor Biomarkers of Retinal Glial Cell Activation in Patients With or Without Age-Related Cataracts and With Different Stages of Diabetic Retinopathy

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Minjie Zhao; Shuzhi Zhao; Min Tang; Tao Sun; Zhi Zheng; Mingming Ma
TAGS: hypertension, biological markers, diabetic retinopathy, neuroglia, aquaporin 1, cataract, senile, cataract, aqueous humor, glial fibrillary acidic protein
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):8. doi: https://doi.org/10.1167/iovs.63.3.8

Lens February 2022

Analyzing Effect of Waterclefts on Visual Functions Via Optical Simulations

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Yusuke Seki; Takushi Kawamorita; Naoki Yamamoto; Takashi Tanigawa; Norihiro Mita; Natsuko Hatsusaka; Eri Kubo; Hiroshi Sasaki
TAGS: optics, vision, lens, crystalline, eye, shape, lens (device)
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):22. doi: https://doi.org/10.1167/iovs.63.2.22

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology January 2022

A Novel Tectal/Pretectal Population of Premotor Lens Accommodation Neurons

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Paul J. May; Paul D. Gamlin; Susan Warren
TAGS: lens (device), lens, crystalline, neurons, rabies, visual accommodation, superior colliculus, injections, rabies virus, ciliary body
Invest. Ophthalmol. Vis. Sci.. 2022; 63(1):35. doi: https://doi.org/10.1167/iovs.63.1.35

Glaucoma January 2022

Occurrence of Oxidative Stress and Premature Senescence in the Anterior Segment of Acute Primary Angle-Closure Eyes

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Dan Ye; Yue Xu; Yuxun Shi; Jianping Ji; Xi Lu; Hailiu Chen; Rong Huang; Peng Lu; Yunxuan Li; Lu Cheng; Yangyunhui Li; Kaixuan Cui; Xiaoyu Tang; Lixia Luo; Jingjing Huang
TAGS: aging, cytokine, eye, older adult, oxidative stress, iris, intraocular pressure, dna, mitochondrial, apoptosis
Invest. Ophthalmol. Vis. Sci.. 2022; 63(1):34. doi: https://doi.org/10.1167/iovs.63.1.34

Includes: Supplemental Content

Lens January 2022

EphA2 Affects Development of the Eye Lens Nucleus and the Gradient of Refractive Index

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Catherine Cheng; Kehao Wang; Masato Hoshino; Kentaro Uesugi; Naoto Yagi; Barbara Pierscionek
TAGS: cell nucleus, lens (device), lens, crystalline, refractive index, ephrins, mice
Invest. Ophthalmol. Vis. Sci.. 2022; 63(1):2. doi: https://doi.org/10.1167/iovs.63.1.2

Includes: Supplemental Content

Lens December 2021

Mitotic Activation Around Wound Edges and Epithelialization Repair in UVB-Induced Capsular Cataracts

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Zongbo Wei; Caili Hao; Ramkumar Srinivasagan; Hongli Wu; Jian-Kang Chen; Xingjun Fan
TAGS: cataract, epithelialization, lens epithelial cell, ultraviolet b radiation, wounds and injuries, mice, lens capsule, crystalline, lens, crystalline, lens (device)
Invest. Ophthalmol. Vis. Sci.. 2021; 62(15):29. doi: https://doi.org/10.1167/iovs.62.15.29

Includes: Supplemental Content

Glaucoma December 2021

Compositional Analysis of Extracellular Aggregates in the Eyes of Patients With Exfoliation Syndrome and Exfoliation Glaucoma

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Alicia De Maria; Keith D. Zientek; Larry L. David; Phillip A. Wilmarth; Anjali M. Bhorade; George J. Harocopos; Andrew J.W. Huang; Augustine R. Hong; Carla J. Siegfried; Linda M. Tsai; Arsham Sheybani; Steven Bassnett
TAGS: exfoliation syndrome, eye, hypertension, lens capsule, crystalline, peeling of skin, proteins, fibrillin-1, proteome, mass spectrometry
Invest. Ophthalmol. Vis. Sci.. 2021; 62(15):27. doi: https://doi.org/10.1167/iovs.62.15.27

Includes: Supplemental Content

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Longitudinal Changes in Lens Thickness and Lens Power Among Persistent Non-Myopic and Myopic Children

Deficiency of Jamc Leads to Congenital Nuclear Cataract and Activates the Unfolded Protein Response in Mouse Lenses

Gene Expression Signatures of Contact Lens-Induced Myopia in Guinea Pig Retinal Pigment Epithelium

Ambient Air Pollution and Age-Related Eye Disease: A Systematic Review and Meta-Analysis

Lens Aquaporin-5 Inserts Into Bovine Fiber Cell Plasma Membranes Via Unconventional Protein Secretion

TFEB-Mediated Lysosomal Restoration Alleviates High Glucose-Induced Cataracts Via Attenuating Oxidative Stress

Sonic Hedgehog Intron Variant Associated With an Unusual Pediatric Cortical Cataract

Oxysterol Compounds in Mouse Mutant αA- and αB-Crystallin Lenses Can Improve the Optical Properties of the Lens

Znhit1 Regulates p21 Cip1 to Control Mouse Lens Differentiation

The E3 Ligase RNF157 Inhibits Lens Epithelial Cell Apoptosis by Negatively Regulating p53 in Age-Related Cataracts

Patterns of Crystallin Gene Expression in Differentiation State Specific Regions of the Embryonic Chicken Lens

RNA Sequencing of Lens Capsular Epithelium Implicates Novel Pathways in Pseudoexfoliation Syndrome

Axial Elongation During Short-Term Accommodation in Myopic and Nonmyopic Children

Aqueous Humor Biomarkers of Retinal Glial Cell Activation in Patients With or Without Age-Related Cataracts and With Different Stages of Diabetic Retinopathy

Analyzing Effect of Waterclefts on Visual Functions Via Optical Simulations

A Novel Tectal/Pretectal Population of Premotor Lens Accommodation Neurons

Occurrence of Oxidative Stress and Premature Senescence in the Anterior Segment of Acute Primary Angle-Closure Eyes

EphA2 Affects Development of the Eye Lens Nucleus and the Gradient of Refractive Index

Mitotic Activation Around Wound Edges and Epithelialization Repair in UVB-Induced Capsular Cataracts

Compositional Analysis of Extracellular Aggregates in the Eyes of Patients With Exfoliation Syndrome and Exfoliation Glaucoma

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