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Retina April 2025

PCARE -Associated Retinopathy – Genetics, Clinical Characteristics, and Natural History

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Lorenzo Bianco; Alessio Antropoli; Amine Benadji; Raphaël Atia; Oana Palacci; Christel Condroyer; Aline Antonio; Julien Navarro; Maurizio Battaglia Parodi; José-Alain Sahel; Christina Zeitz; Isabelle Audo
TAGS: genetics, natural history, retinal diseases, visual impairment, follow-up, eye
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):61. https://doi.org/10.1167/iovs.66.4.61

Includes: Supplemental Content

Genetics April 2025

Detailed Clinical, Ophthalmic, and Genetic Characterization of MYO7A -Associated Usher Syndrome

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Juan C. Romo-Aguas; Thales A. C. de Guimarães; Angelos Kalitzeos; Nancy Aychoua; Chrysanthi Tsika; Anthony G. Robson; Yu Fujinami-Yokokawa; Kaoru Fujinami; Omar A. Mahroo; Andrew R. Webster; Michel Michaelides
TAGS: eye, follow-up, genetics, natural history, usher syndrome, cohort studies, phenotype, retinal imaging, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):60. https://doi.org/10.1167/iovs.66.4.60

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics April 2025

The Relationship Between Binocular Imbalance and Myopic Shift in Unoperated Eyes After Unilateral SMILE and tPRK

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Kaiyan Huang; Mi Xia; Qianwen Gong; Kexin Li; Yijie Xu; Hui Wang; Yuzhou Wang; Jiawei Zhou; Liang Hu
TAGS: eye, imbalance, spatial frequency
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):32. https://doi.org/10.1167/iovs.66.4.32

Includes: Supplemental Content

Visual Neuroscience April 2025

Depth-Related Visuomotor Performance in Keratoconus and Its Relationship to Stereopsis

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Preetirupa Devi; Christa M. Bhengra; Deepak Kumar; Rashmi Deshmukh; Pravin K. Vaddavalli; Joshua A. Solomon; Christopher W. Tyler; Shrikant R. Bharadwaj
TAGS: depth perception, keratoconus, task performance and analysis, vision, contact lenses, muscle rigidity, image quality
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):31. https://doi.org/10.1167/iovs.66.4.31

Visual Psychophysics and Physiological Optics April 2025

Arabic Reading Performance With a Chromatic Acuity Chart

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Balsam Alabdulkader; Ali Almustanyir; Norah Alsalem; Essam Almutleb; Mosaad Alhassan; Jeffery K. Hovis
TAGS: arabic, reading (activity), luminance, color
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):3. https://doi.org/10.1167/iovs.66.4.3

Retina March 2025

Comparison Between MAIA and MP-3 In Healthy Subjects and Patients With Diabetes, Diabetic Retinopathy, and Age-Related Macular Degeneration

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Anna Marmalidou; Haleema Siddiqui; Muhammad Usman Jamil; Kwang Min Woo; Antonio Yaghy; A. Yasin Alibhai; Hiroyuki Takahashi; Stephanie Kaiser; Keith Effert; Peter Y. Zhao; Shilpa J. Desai; Christopher C. Robinson; Jay S. Duker; Nadia K. Waheed
TAGS: age-related macular degeneration, diabetes mellitus, diabetic retinopathy, eye, linear regression
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):59. https://doi.org/10.1167/iovs.66.3.59

Multidisciplinary Ophthalmic Imaging March 2025

Three-Dimensional Choroidal Vessels Assessment in Diabetic Retinopathy

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Elham Sadeghi; Katherine Du; Oluwaseyi Ajayi; Elli Davis; Nicola Valsecchi; Mohammed Nasar Ibrahim; Sandeep Chandra Bollepalli; Kiran Kumar Vupparaboina; Jose Alain Sahel; Jay Chhablani
TAGS: cortical blindness, diabetic retinopathy, eye, cardiovascular imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):50. https://doi.org/10.1167/iovs.66.3.50

Low Vision March 2025

EFEMP1-Mediated Regulation of Choroidal Vascular Dysfunction in Myopia: Insights Into the FOXO3/VEGFA Pathway as a Therapeutic Target

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Wen-Qing Shi; Bing Li; Yuting Shao; Wenting Han; Yule Xu; Qing Jiang; Shen Qu; Xiaodong Zhou; Yanlong Bi
TAGS: forkhead box protein o3, myopia, pathophysiology, caviidae, regulation, choroid, proteins
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):43. https://doi.org/10.1167/iovs.66.3.43

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics March 2025

Age-Related Changes in Mesopic Reading Vision Across Adulthood

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Boris Peñaloza; Traci-Lin Goddin; David S. Friedman; Cynthia Owsley; MiYoung Kwon
TAGS: reading (activity), vision, adult
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):40. https://doi.org/10.1167/iovs.66.3.40

Cornea March 2025

A Novel Model for Cornea Power Shift in Eyes Wearing Orthokeratology Lenses With Different Back Optic Zone Diameters for Myopia Control

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Ting Wang; Xiaoqin Chen; Mengdi Li; Hua Bi; Xiaoyan Yang; Muhan Sun; Yue Liu; Lihua Li; Bin Zhang
TAGS: cornea, eye, lens (device), lens, crystalline, myopia, orthokeratology contact lenses, optics
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):29. https://doi.org/10.1167/iovs.66.3.29

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology March 2025

Distribution of Globe Excursions Within the Orbits Monitored by Eye Tracking Glasses in Ambulatory Subjects Engaged in Their Normal Daily Activities

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Yicen J. Zheng; Thomas N. Gentry; John R. Economides; Jonathan C. Horton
TAGS: eye, eyeglasses, eye-tracking, orbit, gaze
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):20. https://doi.org/10.1167/iovs.66.3.20

Includes: Supplemental Content

Retina February 2025

Correlations Between Visual Field Defects and Macular Thinning in Sickle Cell Disease

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Alexandre Bourdin; Brigitte Ranque; Edouard Flamarion; Jacques Charlier; Jean-Benoît Arlet; Christophe Orssaud
TAGS: drepanocytes, macular disorders, sickle cell anemia, visual field defects, visual fields
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):67. https://doi.org/10.1167/iovs.66.2.67

Includes: Supplemental Content

Low Vision February 2025

Is the Normal Periphery in Young Adults a Good Model for Reading in the Presence of Central Vision Loss?

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Susana T. L. Chung; Gordon E. Legge
TAGS: blindness, reading (activity), reading speed, young adult
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):62. https://doi.org/10.1167/iovs.66.2.62

Visual Neuroscience February 2025

OCT-Based Retina Assessment Reflects Visual Impairment in Multiple Sclerosis

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Natacha Stolowy; Lilija Gutmann; Margareta Lüpke; Thierry David; Michael Dorr; Christina Mayer; Christoph Heesen; Frederike Cosima Oertel; Ting-Yi Lin; Friedemann Paul; Hanna Gwendolyn Zimmermann; Jan-Patrick Stellmann
TAGS: multiple sclerosis, optic neuritis, retina, vision, visual impairment, eye, medical history
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):39. https://doi.org/10.1167/iovs.66.2.39

Includes: Supplemental Content

Cornea February 2025

Contact Lens Wear Alters Transcriptional Responses to Pseudomonas aeruginosa in Both the Corneal Epithelium and the Bacteria

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Naren Gajenthra Kumar; Melinda R. Grosser; Stephanie Wan; Daniel Schator; Eugene Ahn; Eric Jedel; Vincent Nieto; David J. Evans; Suzanne M. J. Fleiszig
TAGS: bacteria, contact lenses, cornea, corneal epithelium, genes, lens (device), lens, crystalline, pseudomonas aeruginosa, transcription, genetic, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):31. https://doi.org/10.1167/iovs.66.2.31

Includes: Supplemental Content

Genetics February 2025

Characterizing the Genetic Basis for Inherited Retinal Disease: Lessons Learned From the Foundation Fighting Blindness Clinical Consortium's Gene Poll

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Kari Branham; Lassana Samarakoon; Isabelle Audo; Allison R. Ayala; Janet K. Cheetham; Stephen P. Daiger; Patty Dhooge; Jacque L. Duncan; Todd A. Durham; Abigail T. Fahim; Rachel M. Huckfeldt; Robert B. Hufnagel; Susanne Kohl; Ramiro S. Maldonado; Michele Melia; Michel Michaelides; Mark E. Pennesi; José-Alain Sahel; Juliana M. Ferraz Sallum; Mandeep S. Singh; Dror Sharon; Kimberly Stepien; Kaylie Jones; Christina Y. Weng; for the Foundation Fighting Blindness Clinical Consortium Investigator Group
TAGS: blindness, genes, genetics, retinal diseases, social survey
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):12. https://doi.org/10.1167/iovs.66.2.12

Includes: Supplemental Content

Clinical and Epidemiologic Research February 2025

Single and Multiple Visual Function Impairments and Associated- Vision-Related Quality of Life Impact in Older Adults Aged 60 to 100 Years

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Preeti Gupta; Tai Anh Vu; Chiew Meng Johnny Wong; Sahil Thakur; Alex A. Black; Joanne M. Wood; Ryan E. K. Man; Eva K. Fenwick; Ecosse L. Lamoureux
TAGS: older adult, prevalence, quality of life, vision
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):18. https://doi.org/10.1167/iovs.66.2.18

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics January 2025

Dynamic Accommodation Responses in Subjects Wearing Myopia Control Spectacles Modifying Peripheral Refraction

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Zhenghua Lin; Dimitrios Christaras; Raul Duarte-Toledo; Zhikuan Yang; Augusto Arias; Weizhong Lan; Pablo Artal
TAGS: eyeglasses, myopia, optics, refraction, visual accommodation, lens (device), lens, crystalline
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):55. https://doi.org/10.1167/iovs.66.1.55

Clinical and Epidemiologic Research January 2025

Ten-Year Change in Visual Function and Incidence of Visual Impairment in Highly Myopic Children and Adults

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Yanping Chen; Ruilin Xiong; Jian Zhang; Shaopeng Yang; Huangdong Li; Ziyu Zhu; Peiyuan Wang; Mingguang He; Yingfeng Zheng; Wei Wang
TAGS: adult, child, eye, incidence, myopia, vision, visual impairment, blindness, world health organization
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):2. https://doi.org/10.1167/iovs.66.1.2

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2024

Natural Course of Refractive Error in Congenital Stationary Night Blindness: Implications for Myopia Treatment

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Mariëlle M. F. Poels; Gerard C. de Wit; Mieke M. C. Bijveld; Maria M. van Genderen
TAGS: myopia, night blindness, congenital stationary, refraction, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):9. https://doi.org/10.1167/iovs.65.14.9

Includes: Supplemental Content

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PCARE -Associated Retinopathy – Genetics, Clinical Characteristics, and Natural History

Detailed Clinical, Ophthalmic, and Genetic Characterization of MYO7A -Associated Usher Syndrome

The Relationship Between Binocular Imbalance and Myopic Shift in Unoperated Eyes After Unilateral SMILE and tPRK

Depth-Related Visuomotor Performance in Keratoconus and Its Relationship to Stereopsis

Arabic Reading Performance With a Chromatic Acuity Chart

Comparison Between MAIA and MP-3 In Healthy Subjects and Patients With Diabetes, Diabetic Retinopathy, and Age-Related Macular Degeneration

Three-Dimensional Choroidal Vessels Assessment in Diabetic Retinopathy

EFEMP1-Mediated Regulation of Choroidal Vascular Dysfunction in Myopia: Insights Into the FOXO3/VEGFA Pathway as a Therapeutic Target

Age-Related Changes in Mesopic Reading Vision Across Adulthood

A Novel Model for Cornea Power Shift in Eyes Wearing Orthokeratology Lenses With Different Back Optic Zone Diameters for Myopia Control

Distribution of Globe Excursions Within the Orbits Monitored by Eye Tracking Glasses in Ambulatory Subjects Engaged in Their Normal Daily Activities

Correlations Between Visual Field Defects and Macular Thinning in Sickle Cell Disease

Is the Normal Periphery in Young Adults a Good Model for Reading in the Presence of Central Vision Loss?

OCT-Based Retina Assessment Reflects Visual Impairment in Multiple Sclerosis

Contact Lens Wear Alters Transcriptional Responses to Pseudomonas aeruginosa in Both the Corneal Epithelium and the Bacteria

Characterizing the Genetic Basis for Inherited Retinal Disease: Lessons Learned From the Foundation Fighting Blindness Clinical Consortium's Gene Poll

Single and Multiple Visual Function Impairments and Associated- Vision-Related Quality of Life Impact in Older Adults Aged 60 to 100 Years

Dynamic Accommodation Responses in Subjects Wearing Myopia Control Spectacles Modifying Peripheral Refraction

Ten-Year Change in Visual Function and Incidence of Visual Impairment in Highly Myopic Children and Adults

Natural Course of Refractive Error in Congenital Stationary Night Blindness: Implications for Myopia Treatment

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